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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Psoriatic arthritis: a clinical entity distinct from psoriasis? 显示文摘 | Ruiz D G Azevedo M N Santos O L | 2012 | Rev Bras Reumatol2012，52，4： | 1 |
| 3 | Development Lengths of High-strength Self-consolidating Concrete Beams 显示文摘 | FLOYD R W RUIZ E O DO N H | 2011 | PCI Journal2011，56，4： | 1 |
| 4 | The genome of Theobroma cacao显示文摘 | Argout X Salse J Aury J M Guiltinan M J Droc G Gouzy J Allegre M Chaparro C Legavre T Maximova S N Abrouk M Murat F Fouet O Poulain J Ruiz M Roguet Y Rodier-Goud M Barbosa-Neto J F Sabot F Kudrna D Ammiraju J S Schuster S C Carlson J E Sallet E Sehiex T D | | 0，，： | 1 |
| 5 | Phytoremediation of Mercury and Organomercurials in Chloroplast Transgenic Plants: Enhanced Root Uptake, Translocation to Shoots, and Volatilization 显示文摘 | HUSSEIN H S RUIZ O N TERRY N | 2007 | Environmental Science and Technology2007，41，24： | 1 |
| 6 | The effect of a ruminal nitrogen (N) deficiency in dairy cows: evaluation of the Cornell Net Carbohydrate and Protein System ruminal nitrogen deficiency adjustment显示文摘 | Ruiz R Tedeschi L O Marini J C Fox D G Pell A N Jarvis G Russell J B | 2002 | Journal of Dairy Science2002，85，： | 1 |
| 7 | Phytoremediation of mercury and organomercurials in chloroplast transgenic plants: enhanced root uptake, translocation to shoots, and volatilization显示文摘 | HUSSEIN H S RUIZ O N TERRY N DANIELL H | 2007 | Environmental Science & Technology2007，41，24： | 1 |
| 8 | Human papillomavirus genotype attribution in invasive cervical cancer:a retrospective cross-sectional worldwide study显示文摘 | de Sanjose S Quint WG Alemany L Geraets DT Klaustermeier JE Lloveras B Tous S Felix A Bravo LE Shin HR Vallejos CS de Ruiz PA Lima MA Guimera N Clavero O Alejo M Llombart-Bosch A Cheng-Yang C Tatti SA Kasamatsu E Iljazovic E Odida M Prado R Seoud M Grce M Usubutun A Jain A Suarez GA Lombardi LE Banjo A Menéndez C Domingo EJ Velasco J Nessa A Chichareon SC Qiao YL Lerma E Garland SM Sasagawa T Ferrera A Hammouda D Mariani L Pelayo A Steiner I Oliva E Meijer CJ AlJassar WF Cruz E Wright TC Puras A Llave CL Tzardi M Agorastos T Garcia-Barriola V Clavel C Ordi J Andújar M Castellsagué X Sánchez GI Nowakowsld AM Bornstein J Mu(n)oz N Bosch FX Retrospective International Survey and HPV Time Trends Study Group | 2010 | Lancet Oncol2010，11，11： | 1 |
| 9 | Characterization of Mercury Bioremediation Bytransgenic Bacteria Expressing Metallothionein and Polyphosphate Kinase显示文摘 | Ruiz O N Alvarez D Gonzalez-Ruiz G | | 0，，： | 1 |
| 10 | The gene doublesex of the fruit fly Anastrepha obliqua ( Diptera, Tephritidae ) 显示文摘 | Ruiz M F Stefani R N Mascarenhas R O | 2005 | Genetics2005，171，2： | 1 |
| 11 | Phytoremediation of organo- mercurial compounds via chloroplast genetic engineering 显示文摘 | Ruiz O Hussein H Terry N | 2003 | Plant Physiology2003，132，3： | 1 |
| 12 | BMP-2 induces Osterix expression through up-regulation of Dlx5 and its phosphorylation by p38显示文摘 | Ulsamer A Ortu(n)o M J Ruiz S Susperregui A R Osses N Rosa J L | 2008 | J Biol Chem2008，283，： | 1 |
| 13 | Norfloxacin Modulates the Inflammatory Response and Directly Affects Neutrophils in Patients With Decompensated Cirrhosis显示文摘 | Pedro Zapater Rocío Ca?o Lucía Llanos Antonio J. Ruiz–Alcaraz Sonia Pascual Claudia Barquero Rocío Moreu Pablo Bellot José F. Horga Carlos Mu?oz Jara Pérez Pilar García–Pe?arrubia Miguel Pérez–Mateo José Such Rubén Francés | 2009 | Gastroenterology2009，，5： | 1 |
| 14 | Biogenic amine production by Oenococcus oeni isolates from malolactic fermen-tation of Tempranillo wine显示文摘 | IZQUIERDO-CA(N)AS P M G(O)MES ALONSO S RUIZ P(E)REZ P | | 0，，04： | 1 |
| 15 | Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients显示文摘 | María A. Nu?ez‐Sánchez Rocío García‐Villalba Tamara Monedero‐Saiz Noelia V. García‐Talavera María B. Gómez‐Sánchez Carmen Sánchez‐álvarez Ana M. García‐Albert Francisco J. Rodríguez‐Gil Miguel Ruiz‐Marín Francisco A. Pastor‐Quirante Francisco Martínez‐Día | 2014 | Food Res2014，，6： | 1 |
| 16 | Headspace solid phase microextraction for the analysis of volatiles in a meat product: dry-cured iberian ham显示文摘 | Jorge Ruiz Ram o n Cava Jes u s Ventanas | 1998 | J Agric Food Chem1998，，46： | 1 |
| 17 | Resveratrol in primary and secondary prevention of cardiovascular disease: a dietary and clinical perspective显示文摘 | Jo?o Tomé‐Carneiro Manuel Gonzálvez Mar Larrosa María J. Yá?ez‐Gascón Francisco J. García‐Almagro José A. Ruiz‐Ros Francisco A. Tomás‐Barberán María T. García‐Conesa Juan Carlos Espín | 2013 | Ann NY Acad Sci2013，，1： | 1 |
| 18 | Graphene oxide :a non- specific enhancer of cellular growth 显示文摘 | Ruiz O N Fernsndo K A S Wang B J | 2011 | American Chemical Society2011，5，10： | 1 |
| 19 | Phytoremediation of organomercurial compounds via chloroplast genetic engineering 显示文摘 | RUIZ O N HUSSEIN H S TERRY N | 2003 | Plant Physiology2003，132，3： | 1 |
| 20 | Phytoremediation of organomercurial compounds via chloroplast genetic engineering显示文摘 | RUIZ O N Hussein H Terry N | 2003 | Plant Physiol2003，132，： | 1 |
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