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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017,9,7: | 11 |
| 2 | Endoscopic submucosal dissection training with pig models in a Western country显示文摘AIM:To test a strategy for endoscopic submucosal dissection(ESD) training in animal models designed to overcome the initial learning curve.METHODS:ESD was attempted in ex vivo and in vivo pig models.Thirty ESD procedures were attempted in the esophagus(n=9) or the stomach(n=21).The ex vivo model was used until initial competence was achieved.In the in vivo model,several ESD procedures were performed in up to 3 sessions.The following variables were analyzed:specimen size,complete and en bloc resection rate,time for circumferential incision,time for submucosal dissection,total ESD duration,and complications.RESULTS:Complete resection was achieved in 28 cases(en bloc 27);2 could not be completed(one perforation,one technical diff iculty).The mean ± SD time for circumferential incision was 36.2±16.8 min(range:8-87 min),and the mean±SD time for submucosal dissection was 45.1±35.7 min(range:9-196 min).The mean±SD size of the resected specimens was 45.2±17.8 mm.The mean±SD total resection time was signif icantly increased for the gastric cases performed in the f irst half of the study(n=13) than in the second half(n=8)(98.9±62.4 min vs 61.7±17.6 min,P=0.04),although the specimen size did not differ.CONCLUSION:Training in animal models could help endoscopists overcome the learning curve before starting ESD in humans. | Adolfo Parra-Blanco María Rosa Arnau David Nicolás-Pérez Antonio Z Gimeno-García Nicolás González Juan A Díaz-Acosta Alejandro Jiménez Enrique Quintero | 2010 | World Journal of Gastroenterology2010,16,23: | 9 |
| 3 | Lipid-Rich Variant of Pancreatic Endocrine Neoplasms显示文摘 | Rajendra Singh Olca Basturk David S Klimstra Giuseppe Zamboni Runjan Chetty Sanaa Hussain Stefano La Rosa Asli Yilmaz Paola Capelli Carlo Capella Jeanette D Cheng N Volkan Adsay | 2006 | The American Journal of Surgical Pathology2006,,2: | 2 |
| 4 | Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico显示文摘 | Perez-Padilla R de la Rosa Zamboni D Ponce de Leon S | 2009 | N Engl J Med2009,361,7: | 1 |
| 5 | Historical CO2 emission and concentrations due to land use change of croplands and pastures by country显示文摘 | Campos C P D Muylaert M S Rosa L P | 2005 | Science of the Total Environment2005,346,: | 1 |
| 6 | Aeute pulmonary em bolism: clinical outcomes in the international cooperalive ppulmo nary embolism registry显示文摘 | Goldhaber S Z Visani L Rosa M D | 1999 | Lancet1999,353,9162: | 1 |
| 7 | The impact of household consumption patterns on emissions in Spain显示文摘 | Rosa D Alfredo M Julio S | 2010 | Energy Economics2010,32,1: | 1 |
| 8 | Trichinella pseudospiralispopulations of the Palearctic region and their relationship with populationsof the Nearctic and Australian regions显示文摘 | La Rosa G Marucci G Zarlenga D S | 2001 | Int J Parasitol2001,31,3: | 1 |
| 9 | Acute pulmonary em- bolismclinical outcomes in the international cooperative pulmo- nary embolism reqistry显示文摘 | Goldhaber S Z Visani L Rosa M D | 1999 | Lancet1999,353,9162: | 1 |
| 10 | Pneumonia and respiratory failure from swine origin influenzaA (H1N1) in Mexico显示文摘 | PerezPadilla R de la Rosa Zamboni D Ponce de Leon S etal | 2009 | N EnglJ Med2009,361,7: | 1 |
| 11 | Triterpenoids and sterol gl- ucoside from cell cultures of Lycopersicon esculentum显示文摘 | Rosa S D Giulio A D Tommonaro G | 1997 | Phyto- chemistry1997,44,5: | 1 |
| 12 | Pneumonia and respiratory failure from swine origin influenza A (H1N1) in Mexico显示文摘 | Perez- Padilla R de la Rosa - Zamboni D Ponce de Leon S | 2009 | N Engl J Med2009,361,7: | 1 |
| 13 | Assessment of heavy metal levels in Almendares River sediments -Havana City, Cuba显示文摘 | OLIVARES-RIEUMONT S DE LA ROSA D LIMA L | 2005 | Water Research2005,,39: | 1 |
| 14 | Post-Miocene expansion, colonization, and host switching drove speciation among extant nematodes of the archaic genus Trichinella 显示文摘 | Zarlenga D S Rosenthal B M La Rosa G | 2006 | Proc Natl Acad Sci U S A2006,103,19: | 1 |
| 15 | New malaria vaccine candidates based on the Plasmodium vivax merozoite surface protein-1 and the TLR-5 agonist Salmonella Typhimurium FliC flagellin显示文摘 | Bargieri D Y Rosa D S Braga C J | 2008 | Vaccine2008,26,: | 1 |
| 16 | An improved state-space method for coupled fluid-structure interaction analysis显示文摘 | CUNEFARE K A ROSA S D | 1999 | Journal of the Acoustical Society of America1999,105,1: | 1 |
| 17 | Sleep deprivation affects inflammatory marker expression in adipose tissue显示文摘 | Rosa N J Lira F S Venancio D P ct al | | 0,,: | 1 |
| 18 | The influence of starch gelatinization on the rheological,thermal,and morphological properties of poly(?-caprolactone)with corn starch blends显示文摘 | Rosa D S Guedes C G F Pedroso A G | 2004 | Materials Science and Engineering:C2004,24,5: | 1 |
| 19 | Neridronate improves bone mineral density and reduces back pain in β-thalassaemia patients with osteoporosis:results from a phase 2,randomized,parallel-arm,open-label study显示文摘 | Forni GL Perrotta S Giusti A Quarta G Pitrolo L Cappellini MD D'Ascola DG Borgna Pignatti C Rigano P Filosa A Iolascon G Nobili B Baldini M Rosa A Pinto V Palummeri E | | 0,,: | 1 |
| 20 | Melatonin protects the liver and erythrocytes aginst oxidative stress in cirrhotic rats显示文摘 | Rosa D P Bona S Simonetto D | 2010 | Arq Gastroenterol2010,47,1: | 1 |