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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | The alpha-adrenoceptor subtype mediating the tension of human prostatic smooth muscle显示文摘 | Lepor H Tang R Shapiro E | 1993 | Prostate1993，22，4： | 1 |
| 3 | Lipids and renal disease显示文摘 | Trevisan R Dodesini AR Lepore G | 2006 | J Am Soc Nephrol2006，17，42： | 1 |
| 4 | Tamsulosin reduces the incidence of acute u- rinary retention following early removal of the urinary catheter after radi- cal retropubic prostatectomy 显示文摘 | Patel R Fiske J Lepor H | 2003 | Urology2003，62，2： | 1 |
| 5 | Medical therapy for benign prostatic hyperplasia显示文摘 | Lepor H Tang R Meretyk S | 1993 | J Urol1993，149，： | 1 |
| 6 | Lipids and renal disease 显示文摘 | Trevisan R Dodesini AR Lepore G | 2006 | J Am Soc Nephrol2006，17，2： | 1 |
| 7 | Effects of hyperbaric oxygen therapy on experimental infarct size:Salvage versus delay of myocardial necrosis显示文摘 | Perrone-Filardi P Lepore S Tifano R | | 0，，： | 1 |
| 8 | Lipids and renal disease显示文摘 | Trevisan R DodesiniA R Lepore G | 2006 | Am Soc Nephrol2006，17，4： | 1 |
| 9 | Modeling and Control of Cement Grinding Processes 显示文摘 | M Boulvin A V Wouwer R Lepore | 2003 | IEEE Transactions on Control Systems Technology2003，11，5： | 1 |
| 10 | The alpha-adrenoceptor subtype mediating the tension of human prostatid smooth muscle显示文摘 | Lepor H Tang R Shapiro E | 1993 | Prostate1993，22，4： | 1 |
| 11 | Deter-mination of aromatic hydrocarbons in urban air of Rome 显示文摘 | Brocco D Fratarcangeli R Lepore L | 1997 | Atmospheric Environment1997，31，： | 1 |
| 12 | Enhancin,the granulosis virus protein that facilitates nucleopolyhedrovirus (NPV) infections,is a metalloprotease显示文摘 | LEPORE L S ROELVINK P R GRANADOS R R | 1996 | Invertebr Pathol1996，68，2： | 1 |
| 13 | Glycosaminoglycan composition of uninjured skin of scar tissue in fetal,newborn & adult sheep显示文摘 | KNIGHT K R HORNE R S LEPORE D A | 1994 | Res Exp Med1994，194，2： | 1 |
| 14 | Durg mixture which improves survival of ischemic rabbit epigastric skin flaps显示文摘 | Dlana A Lepore M S Kenneth R | 1994 | Microsurgery1994，15，： | 1 |
| 15 | Role of priming stresses and HSPT0 in protection from ischemia- reperfusion injury in cardiac and skeletal muscle 显示文摘 | Lepore D A Knight K R Anderson R L | 2001 | Cell Stress Chaperones2001，6，2： | 1 |
| 16 | Lipids and renal disease 显示文摘 | Trevisan R Dodesini AR Lepore G | 2006 | J Am Soe Nephrol2006，17，42： | 1 |
| 17 | Lipids and renal disease显示文摘 | Trevisan R Dodesini A R Lepore G | 2006 | JAm Soc Nephrol2006，17，42： | 1 |
| 18 | Determination of aromatic hydrocarbons in urban air of Rome 显示文摘 | Brocco D Fratarcangeli R Lepore L | 1997 | Atmospheric Environment1997，31，4： | 1 |
| 19 | Determination of aromatic hydrocarbons in urban air of Rome 显示文摘 | Brocco D Fratarcangeli R Lepore L | 1997 | Atmospheric Environment1997，31，4： | 1 |
| 20 | Category and stereotype activation is prejudice inevitable显示文摘 | Brown R | 1997 | Journal of Personality and Social Psychology1997，72，2： | 1 |
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