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| 1 | Cirrhotic cardiomyopathy:Isn't stress evaluation alwaysrequired for the diagnosis?显示文摘AIM:To describe the proportion of patients with cirrhotic cardiomyopathy(CCM) evaluated by stress echocardiography and investigating its association with the severity of liver disease.METHODS:A cross-sectional study was conducted.Cirrhotic patients without risk factors for cardiovascular disease were included.Data regarding etiology and severity of liver disease(Child-Pugh score and model for end-stage liver disease),presence of ascites and gastroesophageal varices,pro-brain natriuretic peptide(proBNP) and corrected QT(QTc) interval were collected.Dobutamine stress echocardiography(conventional and tissue Doppler imaging) was performed.CCM was considered present when diastolic and/or systolic dysfunction was diagnosed at rest or after pharmacological stress.Therapy interfering with cardiovascular system was suspended 24 h before the examination.RESULTS:Twenty-six patients were analyzed,17(65.4%) Child-Pugh A,mean model for end-stage liver disease(MELD) score of 8.7.The global proportion of patients with CCM was 61.5%.At rest,only 2(7.7%)patients had diastolic dysfunction and none of the patients had systolic dysfunction.Dobutamine stress echocardiography revealed the presence of diastolic dysfunction in more 6(23.1%) patients and of systolic dysfunction in 10(38.5%) patients.QTc interval prolongation was observed in 68.8%of the patients and increased pro-BNP levels in 31.2%of them.There was no association between the presence of CCM and liver impairment assessed by Child-Pugh score or MELD(P= 0.775,P= 0.532,respectively).Patients with QTc interval prolongation had a significant higher rate of gastroesophageal varices comparing with those without QTc interval prolongation(95.0%vs 50.0%,P= 0.028).CONCLUSION:CCM is a frequent complication of cirrhosis that is independent of liver impairment.Stress evaluation should always be performed,otherwise it will remain an underdiagnosed condition. | mara barbosa joana guardado carla marinho bruno rosa isabel quelhas antónio lourenco josécotter | 2016 | World Journal of Hepatology2016，8，3： | 5 |
| 2 | High-precision geochronology of Mesozoic magmatism in Macao,Southeast China:Evidence for multistage granite emplacement显示文摘Six new high precision U-Pb zircon ID-TIMS ages plus thirteen in situ high spatial resolution U-Pb zircon LA-MC-ICPMS ages are reported from Jurassic plutonic(metaluminous to weakly peraluminous biotite granites)and Jurassic to Cretaceous hypabyssal(dacites)rocks from Macao.Despite its relatively small area(~30 km^2),the new ages tightly constrain the Macao granitic magmatism to two periods ranging from 164.5±0.6 Ma to 162.9±0.7 Ma and 156.6±0.2 Ma to 155.5±0.8 Ma,separated by ca.6 Ma.Inherited zircons point to the existence of a basement with ages up to Paleo-Proterozoic and late Archean in the region.In addition,younger dacitic rocks were dated at 150.6±0.6 Ma and<120 Ma.U-Pb zircon ages and whole-rock REE data of Macao granites indicate that the first pulse is also represented in Hong Kong and Southeast(SE)China,while magmatism with the chemical characteristics of the second pulse seems to not be represented outside Macao.The two granitic magmatic pulses have distinct mineralogical and geochemical features that support their discrete nature rather than a continuum of comagmatic activity and suggest that the Macao granitic suite was incrementally assembled during a period of ca.9 Ma,a hypothesis also extendable to the neighboring Hong Kong region for a time lapse of ca.24 Ma.In Macao,the transition from granitic magmatism(Middle to Upper Jurassic)to the younger dacite dykes(Upper Jurassic to Lower Cretaceous)most likely corresponds to a change in the regional tectonic setting,from an extensional regime related with foundering of the subducting paleoPacific plate during the Early Yanshanian period to the reestablishment of a normal subduction system in SE China during the Late Yanshanian period. | Pedro Quelhas Agata Alveirinho Dias Joao Mata Donald Wayne Davis Maria Luísa Ribeiro | 2020 | Geoscience Frontiers2020，11，1： | 2 |
| 3 | Clinical trial of a self-etching adhesive for sealant application:success at 24 months with Prompt L-Pop显示文摘 | Feigal RJ Quelhas I | 2003 | Am J Dent2003，16，4： | 1 |
| 4 | Effect of green tea marinades on the formation of heterocyclic aromatic amines and sensory quality of pan-fried beef显示文摘 | Quelhas I Petisca C Viegas O | | 0，，01： | 1 |
| 5 | Detailed glycan analysis of serum glycoproteins of patients with congenital disorders of glycosylation indicates the specific defective glycan processing step and provides an insight into pathogenesis显示文摘 | Butler M Quelhas D Critchley A J | 2003 | Glycobiology2003，13，9： | 1 |
| 6 | Effect of green tea mari- nades on the formation of heterocyclic aromatic amines and sensory quality of pan-fried beef显示文摘 | QUELHAS I PETISCA C VIEGAS O | 2010 | Food Chemistry2010，122，1： | 1 |
| 7 | A thousand words in a scene显示文摘 | Quelhas P Monay F Odobez J M | 2007 | IEEE Transactions on Pattern Analysis and Machine Intelligence(S0162-8828)2007，29，15： | 1 |
| 8 | RTS,S/ASO2A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection显示文摘 | Enosse S Dobafio C Quelhas D | 2006 | PLoS Clin Trials2006，1，1： | 1 |
| 9 | A thousand words in a scene显示文摘 | Quelhas P Monay F Odobez J | 2007 | IEEE Transactions on Pattern Analysis and Machine Intelligence2007，29，9： | 1 |
| 10 | A thousand words in a scene 显示文摘 | Quelhas P Monay F Odobez J M | 2007 | IEEE Transactions on Pattern Analysis and Machine Intelligence2007，29，9： | 1 |
| 11 | Comparative effects of vaporized perfluorohexane and partial liquid ventilation in oleic acid-induced lung injury显示文摘 | De Abreu MG Quelhas AD | 2006 | Anesthesiol2006，104，2： | 1 |
| 12 | Automa-ted Arabidopsis plant root cell segmentation based on SVMclassification and region merging显示文摘 | Monica Marcuzzo Pedro Quelhas Ana Campilho | 2009 | Computers In Biologyand Medicine2009，39，9： | 1 |
| 13 | A thousand words in a scene 显示文摘 | Quelhas P Monay F Odobez J M | 2007 | IEEE Transactions on Pattern Analysis and Machine Intelligence2007，29，9： | 1 |
| 14 | A thousand words in ascene 显示文摘 | Quelhas P Monay F Odobez J M | 2007 | IEEE Transactions on Pattern Analysis and MachineIntelligence2007，29，9： | 1 |
| 15 | Effect of green tea marinades on the formation of heterocyclic aromatic amines and sensory quality of pan-fried beef显示文摘 | I. Quelhas C. Petisca O. Viegas A. Melo O. Pinho I.M.P.L.V.O. Ferreira | 2010 | Food Chemistry2010，，1： | 1 |
| 16 | Contextual Classification of Image Patches with Latent Aspect Models显示文摘 | Monay F Quelhas P Odobez J M | 2009 | EURASIP Journal on hnage and Video Processing2009，2009，： | 1 |
| 17 | Effect of green tea marinades on the formation of heterocyclic aromatic amines and sensory quality of pan-fried beef显示文摘 | QUELHAS I PETISCA C VIEGAS O | 2010 | Food Chemistry2010，122，1： | 1 |
| 18 | Effect of green tea marinades on the formation of heterocyclic aromatic amines and sensory quality of pan-fried beef显示文摘 | QUELHAS I PETISCA C VIEGAS O | 2010 | Food Chemistry2010，122，1： | 1 |
| 19 | A thousand words in a scene 显示文摘 | QUELHAS P MONAY F ODOBEZ J M | 2007 | IEEE Transactions on Pattern Analysis and Machine Intelligence2007，29，9： | 1 |
| 20 | A thousand words in a scene显示文摘 | QUELHAS P MONAY F ODOBEZ J M | 2007 | IEEE Transactions on Pattern Analysis and Machine Intelligence2007，29，9： | 1 |
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