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| 1 | Effect of melatonin on the severity of L-arginine-induced experimental acute pancreatitis in rats显示文摘瞄准:决定 melatonin 预告的处理的效果并且在 L 精氨酸(L-Arg ) 的严厉上处理以后在老鼠的导致的试验性的胰腺炎。方法:男 Wistar 老鼠(25 ) 被划分成五个组。那些在 1h 的间隔在组 A 收到了 3.2g/kg 体重 L-Arg i.p 的二注射。在组麻省,老鼠与 50 mg/kg 体重 melatonin i.p 被对待在 L-Arg 管理以前的 30 min。在组 AM,在 L-Arg 被给以后,老鼠收到了 melatonin 1h 的一样的剂量。在组 M, melatonin 的单次量是以前描述了被管理。在组 C,对照动物收到了生理盐水注射 i.p 所有老鼠被给在第二 L-Arg 注射以后的 24 h。结果:引起严重引起坏死胰腺炎的 L-Arg 管理在浆液淀粉酶水平,胰腺的重量 / 身体重量比率(pw/bw ) ,胰腺的 IL-6 内容和 myeloperoxidase 由重要举起证实了活动,相对控制值。浆液淀粉酶水平的举起显著地在与仅仅与 L-Arg 注射的老鼠相比给 melatonin 追随者 L-Arg 的老鼠被减少。胰腺的抗氧化剂酶(Cu/Zn-superoxide 歧化酶(Cu/Zn-SOD ) 和过氧化氢酶(猫)) 的活动显著地被增加在胰腺炎以后的 24 h 感应。显著地在 L-Arg 之前给的 Melatonin 在独自与 L-Arg 对待的老鼠相对那减少了胰腺的猫活动。在肝, L-Arg 显著地每氧化水平,和谷胱甘肽过氧化物酶和 Cu/Zn-SOD 活动增加了类脂化合物,而 Mn 草皮活动作为与控制老鼠相比被减少。Melatonin 预告的处理阻止了这些变化。结论:Melatonin 是能在尖锐胰腺炎期间抵抗一些 L-Arg-induced 变化的一种抗氧化剂,并且可能因此在有尖锐引起坏死胰腺炎的病人的支持的治疗有用。 | Annamaria Szabolcs Russel J Reiter Tamas Letoha Peter Hegyi Gabor Papai Ilona Varga Katalin Jarmay Jozsef Kaszaki Reka Sari Zoltan Rakonczay Jr Janos Lonovics Tamas Takacs | 2006 | World Journal of Gastroenterology2006，12，2： | 13 |
| 2 | Combining Lithoclast and ultrasound power in one device for percutaneous nephrolithotomy: in vitro results of a novel and highly effective technology显示文摘 | Peter Olbert Jost Weber Axel Hegele Zoltan Varga Axel Heidenreich Rainer Hofmann | 2003 | Urology2003，，1： | 4 |
| 3 | Preparation and Structural Characterization of Rapidly Solidified Al-Cu Alloys显示文摘Rapidly solidified Al100-x—Cux alloys(x = 5,10,1 5,25,35 wt%) were prepared and analyzed.High cooling rate increased the Cu solubility in 9.-AI matrix.The influence of the cooling rate on Cu solubility extension in Al was experimentally simulated.Thus the pouring was performed in metallic die and by melt spinning-low pressure(MSLP) technique.Melt processing by liquid quenching was performed using a self-designed melt spinning set-up which combined the cooling technology of a melt jet on the spinning disc with the principle of the mold feeding from low pressure casting technology.The thickness of the melt-spun ribbons was in the range of30—70 μm.The cooling rate provided by MS-LP was within 105—106 K/s after the device calibration.The obtained alloys were characterized from structural,thermal and mechanical point of view.Optical microscopy and scanning electron microscopy were employed for the microstructural characterization which was followed by X-ray analysis.The thermal properties were evaluated by dilatometric and differential scanning calorimetric measurements.Vickers microhardness measurements were performed in the study.In the case of the hypereutectic alloy with 35 wt%Cu obtained by MS-LP method,the microhardness value increased by 45%compared to the same alloy obtained by gravity casting method.This was due to the extended solubility of the alloying element in the α-AI solid solution. | Iuliana Lichioiu Ildiko Peter Bela Varga Mario Rosso | 2014 | Journal of Materials Science & Technology2014，30，4： | 3 |
| 4 | Autonomic and sensory nerve dysfunction in primary biliary cirrhosis显示文摘AIM: Cardiovascular autonomic and peripheral sensory neuropathy is a known complication of chronic alcoholic and non-alcoholic liver diseases. We aimed to assess the prevalence and risk factors for peripheral sensory nerve and autonomic dysfunction using sensitive methods in patients with primary biliary cirrhosis (PBC). METHODS: Twenty-four AMA M2 positive female patients with clinical, biochemical and histological evidence of PBC and 20 age matched healthy female subjects were studied. Five standard cardiovascular reflex tests and 24-h heart rate variability (HRV) analysis were performed to define autonomic function. Peripheral sensory nerve function on median and peroneal nerves was characterized by current perception threshold (CPT), measured by a neuroselective diagnostic stimulator (Neurotron, Baltimore, MD). RESULTS: Fourteen of 24 patients (58%) had at least one abnormal cardiovascular reflex test and thirteen (54%) had peripheral sensory neuropathy. Lower heart rate response to deep breathing (P=0.001), standing (P=0.03) and Valsalva manoeuvre (P=0.01), and more profound decrease of blood pressure after standing (P=0.03) was found in PBC patients than in controls. As a novel finding we proved that both time domain and frequency domain parameters of 24-h HRV were significantly reduced in PBC patients compared to controls. Each patient had at least one abnormal parameter of HRV. Lower CPT values indicated hyperaesthesia as a characteristic feature at peroneal nerve testing at three frequencies (2000 Hz: P=0.005; 250 Hz: P=0.002; 5 Hz: P=0.004) in PBC compared to controls. Correlation of autonomic dysfunction with the severity and duration of the disease was observed. Lower total power of HRV correlated with lower CPT values at median nerve testing at 250 Hz (P = 0.0001) and at 5 Hz (P=0.002), as well as with those at peroneal nerve testing at 2000 Hz (P=0.01). CONCLUSION: Autonomic and sensory nerve dysfunctions are frequent in PBC. Twenty-four-hour HRV analysis is more sensitive than standard cardiovascular tests for detecting of both parasympathetic and sympathetic impairments. Our novel data suggest that hyperaesthesia is a characteristic feature of peripheral sensory neuropathy and might contribute to itching in PBC. Autonomic dysfunction is related to the duration and severity of PBC. | Katalin Keresztes lldikó Istenes Aniko Folhoffer Peter L Lakatos Andrea Horvath Timea Csak Peter Varga Peter Kempler Ferenc Szalay | 2004 | World Journal of Gastroenterology2004，10，20： | 2 |
| 5 | Deep vein thrombosis resolution is modulated by monocyte CXCR2 -mediated activity in a mouse model 显示文摘 | Peter K Varga A Sumit D | 2004 | Arteriosclerosis Thrombosis and Vascular Biology2004，24，： | 1 |
| 6 | Staphylococcus aureus Panton-Valentine leukocidin is a very potent cytotoxic factor for human neutrophils 显示文摘 | Loffler B Hussain M Grundmeier M Brfick M Holzinger D Varga G Roth J Kahl BC Proctor RA Peters G | 2010 | PLoS Pathog2010，6，10： | 1 |
| 7 | The role of epigenetics in the regulation of apoptosis in myelodysplastic syndromes and acute myeloid leukemia显示文摘 | Heidrun Karlic Harald Herrmann Franz Varga Roman Thaler Rene Reitermaier Silvia Spitzer Viviane Ghanim Katharina Blatt Wolfgang R. Sperr Peter Valent Michael Pfeilst?cker | 2013 | Critical Reviews in Oncology / Hematology2013，，： | 1 |
| 8 | α-Galactosidase A Deficiency Accelerates Atherosclerosis in Mice With Apolipoprotein E Deficiency显示文摘 | Peter F. Bodary Yuechun Shen Fernando B. Vargas Xiaoming Bi Kristen A. Ostenso Shufang Gu James A. Shayman Daniel T. Eitzman | 2005 | Circulation2005，，5： | 1 |
| 9 | O007 : All oral HCV therapy is safe and effective in patients with decompensated cirrhosis: Interim report from the HCV-target real world experience显示文摘 | R. Reddy J.K. Lim A. Kuo A.M. Di Bisceglie H.E. Vargas J.S. Galati G. Morelli G.T. Everson P.Y. Kwo R.S. Brown M.S. Sulkowski T.G. Stewart L. Akuskevich M. Vainorius J.A. Peter D.R. Nelson M.W. Fried M.P. Manns | 2015 | Journal of Hepatology2015，，： | 1 |
| 10 | FungalTraits:a user-friendly traits database of fungi and fungus-like stramenopiles显示文摘The cryptic lifestyle of most fungi necessitates molecular identification of the guild in environmental studies.Over the past decades,rapid development and affordability of molecular tools have tremendously improved insights of the fungal diversity in all ecosystems and habitats.Yet,in spite of the progress of molecular methods,knowledge about functional properties of the fungal taxa is vague and interpretation of environmental studies in an ecologically meaningful manner remains challenging.In order to facilitate functional assignments and ecological interpretation of environmental studies we introduce a user friendly traits and character database FungalTraits operating at genus and species hypothesis levels.Combining the information from previous efforts such as FUNGuild and FunFun together with involvement of expert knowledge,we reannotated 10,210 and 151 fungal and Stramenopila genera,respectively.This resulted in a stand-alone spreadsheet dataset covering 17 lifestyle related traits of fungal and Stramenopila genera,designed for rapid functional assignments of environmental stud-ies.In order to assign the trait states to fungal species hypotheses,the scientific community of experts manually categorised and assigned available trait information to 697,413 fungal ITS sequences.On the basis of those sequences we were able to summarise trait and host information into 92,623 fungal species hypotheses at 1%dissimilarity threshold. | Sergei Põlme Kessy Abarenkov RHenrik Nilsson Björn D.Lindahl Karina Engelbrecht Clemmensen Havard Kauserud Nhu Nguyen Rasmus Kjøller Scott T.Bates Petr Baldrian Tobias Guldberg Frøslev Kristjan Adojaan Alfredo Vizzini Ave Suija Donald Pfister Hans-Otto Baral Helle Järv Hugo Madrid Jenni Nordén Jian-Kui Liu Julia Pawlowska Kadri Põldmaa Kadri Pärtel Kadri Runnel Karen Hansen Karl-Henrik Larsson Kevin David Hyde Marcelo Sandoval-Denis Matthew E.Smith Merje Toome-Heller Nalin N.Wijayawardene Nelson Menolli Jr Nicole K.Reynolds Rein Drenkhan Sajeewa S.N.Maharachchikumbura Tatiana B.Gibertoni Thomas Læssøe William Davis Yuri Tokarev Adriana Corrales Adriene Mayra Soares Ahto Agan Alexandre Reis Machado Andrés Argüelles-Moyao Andrew Detheridge Angelina de Meiras-Ottoni Annemieke Verbeken Arun Kumar Dutta Bao-Kai Cui C.K.Pradeep César Marín Daniel Stanton Daniyal Gohar Dhanushka N.Wanasinghe Eveli Otsing Farzad Aslani Gareth W.Griffith Thorsten H.Lumbsch Hans-Peter Grossart Hossein Masigol Ina Timling Inga Hiiesalu Jane Oja John Y.Kupagme József Geml Julieta Alvarez-Manjarrez Kai Ilves Kaire Loit Kalev Adamson Kazuhide Nara Kati Küngas Keilor Rojas-Jimenez Krišs Bitenieks Laszlo Irinyi LászlóGNagy Liina Soonvald Li-Wei Zhou Lysett Wagner M.Catherine Aime MaarjaÖpik María Isabel Mujica Martin Metsoja Martin Ryberg Martti Vasar Masao Murata Matthew PNelsen Michelle Cleary Milan C.Samarakoon Mingkwan Doilom Mohammad Bahram Niloufar Hagh-Doust Olesya Dulya Peter Johnston Petr Kohout Qian Chen Qing Tian Rajasree Nandi Rasekh Amiri Rekhani Hansika Perera Renata dos Santos Chikowski Renato L.Mendes-Alvarenga Roberto Garibay-Orijel Robin Gielen Rungtiwa Phookamsak Ruvishika S.Jayawardena Saleh Rahimlou Samantha C.Karunarathna Saowaluck Tibpromma Shawn P.Brown Siim-Kaarel Sepp Sunil Mundra Zhu-Hua Luo Tanay Bose Tanel Vahter Tarquin Netherway Teng Yang Tom May Torda Varga Wei Li Victor Rafael Matos Coimbra Virton Rodrigo Targino de Oliveira Vitor Xavier de Lima Vladimir S.Mikryukov Yongzhong Lu Yosuke Matsuda Yumiko Miyamoto Urmas Kõljalg Leho Tedersoo | 2020 | Fungal Diversity2020，，6： | 1 |
| 11 | Degradation of ochratoxin A and other mycotoxin by Rhizopus isolates显示文摘 | Varga J Peter Z Tabori K | 2005 | Int J food icrobial2005，99，： | 1 |
| 12 | Drought stress and tropical maize: QTL-by-environment interactions and stability of QTLs across environments for yield components and secondary traits显示文摘 | Rainer Messmer Yvan Fracheboud Marianne B?nziger Mateo Vargas Peter Stamp Jean-Marcel Ribaut | 2009 | Theoretical and Applied Genetics2009，，5： | 1 |
| 13 | Magnetic Resonance Imaging for Predicting Prostate Biopsy Findings in Patients Considered for Active Surveillance of Clinically Low Risk Prostate Cancer显示文摘 | Hebert Alberto Vargas Oguz Akin Asim Afaq Debra Goldman Junting Zheng Chaya S. Moskowitz Amita Shukla-Dave James Eastham Peter Scardino Hedvig Hricak | 2012 | The Journal of Urology2012，，： | 1 |
| 14 | Advances in plant gene - targeted and functional markers : a review 显示文摘 | Poczai Peter Varga Ildiko Laos Maarja | 2013 | Plant Methods2013，9，： | 1 |
| 15 | Intrinsic defects on a TiO 2 (110)(1×1) surface and their reaction with oxygen: a scanning tunneling microscopy study显示文摘 | Ulrike Diebold Jeremiah Lehman Talib Mahmoud Markus Kuhn Georg Leonardelli Wilhelm Hebenstreit Michael Schmid Peter Varga | 1998 | Surface Science1998，，1： | 1 |
| 16 | Ion channels in T lymphocytes: An update on facts, mechanisms and therapeutic targeting in autoimmune diseases显示文摘 | Zoltan Varga Peter Hajdu Gyorgy Panyi | 2009 | Immunology Letters2009，，1： | 1 |
| 17 | Preparation and Structural Characterization of Rapidly Solidified Al–Cu Alloys显示文摘 | Iuliana Lichioiu Ildiko Peter Bela Varga Mario Rosso | 2012 | Journal of Materials Science & Technology2012，，： | 1 |
| 18 | 4-Fluorosulfonylpiperidines: Selective 5-HT 2A ligands for the treatment of insomnia显示文摘 | L. Rebecca Fish Myra T. Gilligan Alexander C. Humphries Magnus Ivarsson Tammy Ladduwahetty Kevin J. Merchant Desmond O’Connor Smita Patel Elisabeth Philipps Hugo M. Vargas Peter H. Hutson Angus M. MacLeod | 2005 | Bioorganic & Medicinal Chemistry Letters2005，，16： | 1 |
| 19 | High‐sensitivity C‐reactive protein for identification of disease phenotype, active disease, and clinical relapses in Crohn’s disease: A marker for patient classification?显示文摘 | Lajos Sandor Kiss Maria Papp Barbara Dorottya Lovasz Zsuzsanna Vegh Petra Anna Golovics Eszter Janka Eva Varga Miklos Szathmari Peter Laszlo Lakatos | 2011 | Inflamm Bowel Dis2011，，9： | 1 |
| 20 | Endoscopic diagnosis of cyromegalovirus infection of upper gastrointestinal tract in solid organ transplant recipients: Hungarian single-center experience显示文摘 | Peter A Telkers G Varga M | 2004 | Clin Transplant2004，18，5： | 1 |
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