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您的检索式：作者名="Aniko Folhoffer"
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| 1 | Autonomic and sensory nerve dysfunction in primary biliary cirrhosis显示文摘AIM: Cardiovascular autonomic and peripheral sensory neuropathy is a known complication of chronic alcoholic and non-alcoholic liver diseases. We aimed to assess the prevalence and risk factors for peripheral sensory nerve and autonomic dysfunction using sensitive methods in patients with primary biliary cirrhosis (PBC). METHODS: Twenty-four AMA M2 positive female patients with clinical, biochemical and histological evidence of PBC and 20 age matched healthy female subjects were studied. Five standard cardiovascular reflex tests and 24-h heart rate variability (HRV) analysis were performed to define autonomic function. Peripheral sensory nerve function on median and peroneal nerves was characterized by current perception threshold (CPT), measured by a neuroselective diagnostic stimulator (Neurotron, Baltimore, MD). RESULTS: Fourteen of 24 patients (58%) had at least one abnormal cardiovascular reflex test and thirteen (54%) had peripheral sensory neuropathy. Lower heart rate response to deep breathing (P=0.001), standing (P=0.03) and Valsalva manoeuvre (P=0.01), and more profound decrease of blood pressure after standing (P=0.03) was found in PBC patients than in controls. As a novel finding we proved that both time domain and frequency domain parameters of 24-h HRV were significantly reduced in PBC patients compared to controls. Each patient had at least one abnormal parameter of HRV. Lower CPT values indicated hyperaesthesia as a characteristic feature at peroneal nerve testing at three frequencies (2000 Hz: P=0.005; 250 Hz: P=0.002; 5 Hz: P=0.004) in PBC compared to controls. Correlation of autonomic dysfunction with the severity and duration of the disease was observed. Lower total power of HRV correlated with lower CPT values at median nerve testing at 250 Hz (P = 0.0001) and at 5 Hz (P=0.002), as well as with those at peroneal nerve testing at 2000 Hz (P=0.01). CONCLUSION: Autonomic and sensory nerve dysfunctions are frequent in PBC. Twenty-four-hour HRV analysis is more sensitive than standard cardiovascular tests for detecting of both parasympathetic and sympathetic impairments. Our novel data suggest that hyperaesthesia is a characteristic feature of peripheral sensory neuropathy and might contribute to itching in PBC. Autonomic dysfunction is related to the duration and severity of PBC. | Katalin Keresztes lldikó Istenes Aniko Folhoffer Peter L Lakatos Andrea Horvath Timea Csak Peter Varga Peter Kempler Ferenc Szalay | 2004 | World Journal of Gastroenterology2004，10，20： | 2 |
| 2 | Holmes-Adie syndrome, autoimmune hepatitis and celiac disease: A case report显示文摘与 Holmes-Adie 的下列症状介绍的一个 35 岁的女病人:畏光,对光无答复的左学生的增大,阿奇里斯无反射。毛果芸香硷测试是阳性的。没有肿瘤或另外的神经病学的反常被发现。她有自体免疫的肝炎的 19 年的历史。闪光在上面被观察跟随每 3 交货。在 31 的年龄,她与腹泻和重量损失介绍了。腹的肿瘤被超声检测。通过手术移开的肿瘤是组织学地良性的 mes 伤寒多膀胱的淋巴管瘤。同时,乳糜泻是 diagnosed.Gluten 免费的饮食导致了乳糜泻,然而并非自体免疫的肝炎的重要改进。自治神经病被标准心血管的测试证明。病人是为为乳糜泻特征、为在自体免疫的肝疾病经常的 HLA DR3 B8 异质接合的 HLA DQ2 抗原的一个同型结合的搬运人。我们有自体免疫的肝炎和乳糜泻的 Holmes-Adie 的协会上的新奇观察为为在有 mes 伤寒的一个病人在场的所有三个实体的一个普通免疫学的背景是暗示的多膀胱的淋巴管瘤。 | Timea Csak Aniko Folhoffer Andrea Horvath Judit Halász Csaba Diczházi Zsuzsa Schaff Ferenc Szalay | 2006 | World Journal of Gastroenterology2006，12，9： | 1 |
| 3 | Serum leptin,soluble leptin receptor,free leptin index and bone mineral density in patients with primary biliary cirrhosis显示文摘 | Ferenc Szalay Aniko Folhoffer Andrea Horvath | 2005 | European Journal of Gastroenterology & Hepatology2005，17，9： | 1 |
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