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| 1 | 美国国家卒中协会短暂性脑缺血发作处理指南显示文摘目的:短暂性脑缺血发作(TIA)是常见和重要的卒中先兆。其处理方法多样,大多数发表的指南在近年来均未被更新。我们试图制定一个全面的、无偏倚的、循证的TIA处理指南。方法:根据一种客观标准(可以预测在该研究领域中执业医师对专家提名的文献测量学方法)挑选出15名专家组成员。通过系统回顾检索到过去发表的指南,由专家对其中的推荐意见的质量进行独立评价。选择出质量最高的推荐意见,然后让专家组采用改良Delphi法通过多次问卷调查的方式进行修订,从而对新的修改达成共识。给专家们提供近期临床研究的系统评价,要求专家根据新的证据判断措辞修改的合理性并且根据证据等级和质量对最终的推荐意见进行评定。不允许专家在预期有可能存在任何利益冲突的专题方面提出推荐意见。结果:通过系统回顾检索到257个指南,其中有13篇文献包括的137条推荐意见符合所有纳入标准。需要6次重复的问卷调查对53条最终推荐意见的措辞达成共识。最终的推荐意见涉及TIA的初步处理、评价、内科治疗、外科治疗和危险因素控制。结论:对TIA患者医疗诊治的最终推荐意见强调了紧急评价和治疗的重要性。这种用于制定本指南的新方法是可行的,考虑到了快速更新并能减少偏倚。 | S. Claiborne Johnston Mai N. Nguyen-Huynh Miriam E. Schwarz Kate Fuller Christina Williams S. Andrew Josephsort Graeme J. Hankey Robert G. Hart Steven R. Levine Jose Biller Robert D. Brown Ralph L. Sacco L. Jaap Kappelle Peter J. Koudstaal Julien Bogousslavsky Louis R. Caplan Jan van Gijn Ale Algra Peter M. Rothwell Harold P. Adams Gregory W. Albers 李海峰(译) | 2007 | 国际脑血管病杂志2007，15，3： | 5 |
| 2 | Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘 | S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney | 2007 | 2007 (9558)2007，，9558： | 3 |
| 3 | Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials显示文摘 | Peter M Rothwell Michelle Wilson Jacqueline F Price Jill FF Belch Tom W Meade Ziyah Mehta | 2012 | The Lancet . 2012 (9826)2012，，： | 2 |
| 4 | Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘 | S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney | 2007 | The Lancet . 2007 (9558)2007，，9558： | 2 |
| 5 | Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials显示文摘 | Peter M Rothwell F Gerald R Fowkes Jill FF Belch Hisao Ogawa Charles P Warlow Tom W Meade | 2011 | The Lancet2011，，9759： | 2 |
| 6 | Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack显示文摘 | S Claiborne Johnston Peter M Rothwell Mai N Nguyen-Huynh Matthew F Giles Jacob S Elkins Allan L Bernstein Stephen Sidney | 2007 | The Lancet2007，，9558： | 2 |
| 7 | Angiographically Defined Collateral Circulation and Risk of Stroke in Patients With Severe Carotid Artery Stenosis显示文摘 | Robert D. Henderson Michael Eliasziw Allan J. Fox Peter M. Rothwell Henry J. M. Barnett | 2000 | Stroke: Journal of the American Heart Association2000，，1： | 2 |
| 8 | Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials显示文摘 | Peter M Rothwell Michelle Wilson Carl-Eric Elwin Bo Norrving Ale Algra Charles P Warlow Tom W Meade | 2010 | 2010 (9754)2010，，9754： | 1 |
| 9 | Limitations of the usual blood-pressure hypothesis and importance of variability,instability,and episodic hypertension显示文摘 | Rothwell Peter M | 2010 | The Lancet2010，375，9718： | 1 |
| 10 | Prognostic signifi cance of visit-to-visit variability,maximum systolic blood pressure,and episodic hypertension显示文摘 | Peter M Rothwell Sally C Howard | 2010 | The Lancet2010，375，9718： | 1 |
| 11 | Effects of beta blockers and calcium-channel blockers on within-individual variability in blood pressure and risk of stroke显示文摘 | Rothwell Peter M Howard Sally C Dolan Eamon | 2010 | Lancet neurology2010，9，5： | 1 |
| 12 | Effect of urgent treatment for transient ischaemic attack and minor stroke on disability and hospital costs (EXPRESS study): aprospective population-based se?quential comparison显示文摘 | Ramon Luengo- Fernandez Alastair M Gray Peter M Rothwell | 2007 | Lancet2007，370，95： | 1 |
| 13 | Endovascular treatment of patients with high-risk symptomatic intracranial vertebrobasilar stenoses:long-term outcomes显示文摘background and purpose We present the long-term outcome after endovascular treatment of symptomatic intracranial posterior circulation stenoses.Methods 30 patients with symptomatic intracranial posterior circulation stenoses exceeding 70% underwent endovascular treatment between 2006 and 2012.Data regarding presentation,follow-up,procedure details,complications and imaging follow-up were reviewed.All surviving patients underwent a phone interview to establish their current Modified Ranking Scales(MRS).results Stenoses of the intracranial vertebral artery(24 patients)and basilar artery(6 patients)were treated with stents(10 patients),angioplasty alone(13 patients)or both(5 patients).Two procedures failed.One patient(3.3%)died after the procedure,two had stroke(6.6%)and one a subarachnoid haemorrhage without ensuing deficit.Two patients(6.7%)had asymptomatic complications(dissection and pseudoaneurysm).The median clinical follow-up time was 7 years.Of the 29 patients who survived the procedure,6 died due to unrelated causes.Three patients(10%)had recurrent strokes and two(6.7%)a transient ischaemic attack in the posterior circulation.Two patients had subsequent middle cerebral artery strokes.Five(16.7%)patients had recurrent stenoses and three(10%)occlusions of the treated artery.Retreatment was performed in six patients,three(10%)with PTA and three(10%)with stenting.Current MRS scores were as follows:nine MRS 0,eight MRS 1,four MRS 2 and one MRS 4.Conclusions Long-term follow-up after endovascular treatment of high-risk symptomatic intracranial posterior circulation stenoses shows few stroke recurrences.Treatment of intracranial vertebral artery stenosis may be beneficial in appropriately selected patients. | Tanja Djurdjevic AndréCunha Ursula Schulz Dennis Briley Peter Rothwell Wilhelm Küker | 2019 | Stroke & Vascular Neurology2019，4，4： | 1 |
| 14 | Effects of β-blocker selectivity on blood pressure variability and stroke: A systematic review显示文摘 | Alastair John Stewart Webb Urs Fischer Peter Malcolm Rothwell | 2011 | Neurology2011，，8： | 1 |
| 15 | Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control: 10-Year Results From the Oxford Vascular Study显示文摘 | Dominic P.J. Howard Amitava Banerjee Jack F. Fairhead Jeremy Perkins Louise E. Silver Peter M. Rothwell | 2013 | Circulation2013，，20： | 1 |
| 16 | Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials显示文摘 | Peter M Rothwell F Gerald R Fowkes Jill FF Belch Hisao Ogawa Charles P Warlow Tom W Meade | 2011 | The Lancet . 2011 (9759)2011，，： | 1 |
| 17 | Genetic Heritability of Ischemic Stroke and the Contribution of Previously Reported Candidate Gene and Genomewide Associations显示文摘 | Steve Bevan Matthew Traylor Poneh Adib-Samii Rainer Malik Nicola L. M. Paul Caroline Jackson Martin Farrall Peter M. Rothwell Cathie Sudlow Martin Dichgans Hugh S. Markus | 2012 | Stroke2012，，12： | 1 |
| 18 | Prognostie signify canoe of visit-to-visit variability, maximum systolic blood pressure,and episodic hyper- tension显示文摘 | Peter M Rothwell Sally C Howard Eamon Dolan | 2010 | Lancet2010，375，9718： | 1 |
| 19 | Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials显示文摘 | Peter M Rothwell Michelle Wilson Carl-Eric Elwin Bo Norrving Ale Algra Charles P Warlow Tom W Meade | 2010 | The Lancet2010，，9754： | 1 |
| 20 | Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials显示文摘 | Peter M Rothwell Jacqueline F Price F Gerald R Fowkes Alberto Zanchetti Maria Carla Roncaglioni Gianni Tognoni Robert Lee Jill FF Belch Michelle Wilson Ziyah Mehta Tom W Meade | 2012 | The Lancet . 2012 (9826)2012，，： | 1 |
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