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| 1 | Metallogenesis related to Mesozoic Granitoids in the Nanling Range, South China and Their Geodynamic Settings显示文摘Affected by the compressive stress from the South-Central (Indo-China) Peninsula, the Indosinianorogenesis, characterized by collision, thrust and uplifting, took place inside the South China Plate during 250?230 Ma.The ages of the Indosinian granitoids in the Nanling Range and vicinity areas are mostly 240?205 Ma, indicating that theywere emplaced in both late collision and post-collision geodynamic environments. No important granite-relatedmetallogenesis occurred in this duration. A post-orogenic setting started at the beginning of the Yanshanian Period, whichcontrolled large-scale granitic magmatism and related metallogenesis. This paper makes the first attempt to divide theYanshanian Period into three sub-periods, i.e. the early, middle and late Yanshanian Periods, based mainly on the featuresof magmatism, especially granitoids and related metallogenesis and their geodynamic environments. The magmaticassociation of the Early Yanshanian (about 185?170 Ma) comprises four categories of magmatism, i.e. basalt, bimodalvolcanics, A-type granite and intraplate high-K calc-alkaline (HKCA) magmatism, which indicates an extension-thinningof lithosphere and upwelling of mantle material to a relative small and local extent. Pb-Zn, Cu and Au mineralizationsassociated with HKCA magmatism represents the first high tide of Mesozoic metallogenesis in the Nanling Range area.During the middle Yanshanian, the lithosphere was subjected to more extensive and intensive extending and thinning, andhence mantle upwelling and basaltic magma underplating caused a great amount of crust remelting granitoids. This periodcan be further divided into two stages. The first stage (170?150 Ma) is represented by large-scale emplacement of crustremelting granites with local tungsten mineralization at its end. The second stage (150?140 Ma) is the most important timeof large-scale mineralizations of non-ferrous and rare metals, e.g. W, Sn, Nb-Ta, Bi, Mo, Be, in the Nanling Range area.The late Yanshanian (140?65 Ma) was generally characterized by full extension and breakup of the lithosphere of SouthChina. However, owing to the influence of the Pacific Plate movement, the eastern part of South China was predominatedby subduction-related compression, which resulted in magmatism of calc-alkaline and shoshonite series and relatedmetallogeneses of Au, Ag, Pb-Zn, Cu and (Mo, Sn), followed by extension in its late stage. In the Nanling Range area, thelate Yanshanian magmatism was represented by granitic volcanic-intrusive complexes and mafic dikes, which aregenetically related to volcanic-type uranium and porphyry tin deposits, and the mobilization-mineralization of uraniumfrom pre-existing Indosinian granites. | HUA Renmin CHEN Peirong ZHANG Wenlan YAO Junming LIN Jinfu ZHANG Zhanshi GU Shengyan LIU Xiaodong QI Huawen | 2005 | Acta Geologica Sinica(English Edition)2005，79，6： | 22 |
| 2 | Cancer-associated fibroblasts in breast cancer:Challenges and opportunities显示文摘The tumor microenvironment is proposed to contribute substantially to the progression of cancers,including breast cancer.Cancer-associated fibroblasts(CAFs)are the most abundant components of the tumor microenvironment.Studies have revealed that CAFs in breast cancer originate from several types of cells and promote breast cancer malignancy by secreting factors,generating exosomes,releasing nutrients,reshaping the extracellular matrix,and suppressing the function of immune cells.CAFs are also becoming therapeutic targets for breast cancer due to their specific distribution in tumors and their unique biomarkers.Agents interrupting the effect of CAFs on surrounding cells have been developed and applied in clinical trials.Here,we reviewed studies examining the heterogeneity of CAFs in breast cancer and expression patterns of CAF markers in different subtypes of breast cancer.We hope that summarizing CAFrelated studies from a historical perspective will help to accelerate the development of CAF-targeted therapeutic strategies for breast cancer. | Dengdi Hu Zhaoqing Li Bin Zheng Xixi Lin Yuehong Pan Peirong Gong Wenying Zhuo Yujie Hu Cong Chen Lini Chen Jichun Zhou Linbo Wang | 2022 | Cancer Communications2022，42，5： | 9 |
| 3 | Systematic Hydrological Evaluation of the Noah-MP Land Surface Model over China显示文摘We evaluate water budget components-namely,soil moisture,runoff,evapotranspiration,and terrestrial water storage (TWS)-simulated by the Noah land surface model with multi-parameterization options (Noah-MP) in China,a large geographic domain challenging for hydrological modeling due to poor observational data and a lack of one single parameterization that can fit for complex hydrological processes.By comparing the model simulations with multi-source reference data,we show that Noah-MP can generally reproduce the overall spatiotemporal patterns of runoff and evapotranspiration over six major river basins,with the annual correlation coefficients generally greater than 0.8 and the Nash-Sutcliffe model efficiency coefficient exceeding 0.5.Among the six basins evaluated,the best model performance is seen over the Huaihe River basin.The temporal trend of the modeled TWS anomalies agrees well with GRACE (Gravity Recovery and Climate Experiment) observations,capturing major flood and drought events in different basins.Experiments with 12 selected physical parameterization options show that the runoff parameterization has a stronger impact on the simulated soil moisture-runoff-evapotranspiration relationships than the soil moisture factor for stomatal resistance schemes,a result consistent with previous studies.Overall,Noah-MP driven by GLDAS forcing simulates the hydrological variables well,except for the Songliao basin in northeastern China,likely because this is a transitional region with extensive freeze-thaw activity,while representations of human activities may also help improve the model performance. | Jingjing LIANG Zongliang YANG Peirong LIN | 2019 | Advances in Atmospheric Sciences2019，36，11： | 4 |
| 4 | Machine learning-assisted systematical polymerization planning:case studies on reversible-deactivation radical polymerization显示文摘The combined influence of chemical composition,molecular weight(MW)and molecular weight distribution(D)on the functions and performances of polymeric materials necessitates simultaneous satisfaction of multidimensional requirements during polymer synthesis.However,the complexity of polymerization reactions often dissuades chemists when precisely accessing diversified polymer targets.Herein,we developed a machine learning(ML)-assisted systematical polymerization planning(SPP)platform for addressing this challenge.With ML model providing integrated navigation of the reaction space,this approach can conduct multivariate analysis to uncover complex interactions between the polymerization result and conditions,prescribing optimal reaction conditions to achieve discretionary polymer targets concerning three dimensions including chemical composition,MWandD values.Given the increasing importance of polymerization in advanced material engineering,this ML-assisted SPP platform provides a universal strategy to access tailored polymers with on-demand prediction of polymerization parameters. | Yu Gu Peirong Lin Chengda Zhou Mao Chen | 2021 | Science China Chemistry2021，64，6： | 2 |
| 5 | PAH in fossils and their geochemical significance显示文摘 | Lin Renzi Wang Peirong | 1991 | Journal of Southeast Asian Earth Sciences1991，5，： | 1 |
| 6 | Metallogenic systems related to Mesozoic and Cenozoic granitoids in South China显示文摘 | Hua Renmin Chen Peirong Zhang Wenlan Liu Xiaodong Lu Jianjun Lin Jinfu Yao Junming Qi Huawen Zhang Zhanshi Gu Shengyan | 2003 | Sci China (D)2003，46，8： | 1 |
| 7 | Organic geochemistry of oils and condensates in the Kekeya Field, Southwest Depression of the Tarim Basin (China) 1 Geological Survey of Canada contribution No. 1998014. 1显示文摘 | Maowen Li Renzi Lin Yongsheng Liao Lloyd R Snowdon Peirong Wang Peilong Li | 1999 | Organic Geochemistry1999，，1： | 1 |
| 8 | Modeling the Impacts of Nitrogen Dynamics on Regional Terrestrial Carbon and Water Cycles over China with Noah-MP-CN显示文摘As an important part of biogeochemical cycling,the nitrogen cycle modulates terrestrial ecosystem carbon storage,water consumption,and environmental quality.Modeling the complex interactions between nitrogen,carbon and water at a regional scale remains challenging.Using China as a testbed,this study presents the first application of the nitrogenaugmented community Noah land surface model with multi-parameterization options(Noah-MP-CN)at the regional scale.Noah-MP-CN parameterizes the constraints of nitrogen availability on photosynthesis based on the Fixation and Uptake of Nitrogen plant nitrogen model and the Soil and Water Assessment Tool soil nitrogen model.The impacts of nitrogen dynamics on the terrestrial carbon and water cycles are investigated by comparing the simulations with those from the original Noah-MP.The results show that incorporating nitrogen dynamics improves the carbon cycle simulations.NoahMP-CN outperforms Noah-MP in reproducing leaf area index(LAI)and gross primary productivity(GPP)for most of China,especially in the southern warm and humid regions,while the hydrological simulations only exhibit slight improvements in soil moisture and evapotranspiration.The impacts of fertilizer application over cropland on carbon fixation,water consumption and nitrogen leaching are investigated through a trade-off analysis.Compared to halved fertilizer use,the actual quantity of application increases GPP and water consumption by only 1.97%and 0.43%,respectively;however,the nitrogen leaching is increased by 5.35%.This indicates that the current level of fertilizer use is a potential concern for degrading the environment. | Jingjing LIANG Zong-Liang YANG Xitian CAI Peirong LIN Hui ZHENG Qingyun BIAN | 2020 | Advances in Atmospheric Sciences2020，37，7： | 0 |
| 9 | Advances of Studies on the Viral Proteins of PRRSV显示文摘Porcine reproductive and respiratory syndrome( PRRS) is one of viral diseases with severe reproductive obstacle of pregnant sows and respiratory tract symptoms and higher mortality of piglets as characteristics,which is caused by porcine reproductive and respiratory syndrome virus( PRRSV). PRRS has brought great threats to swine industry in the world. The advances of studies on the viral proteins of PRRSV were reviewed from the genome,non-structural proteins and structural proteins of PRRSV. | Cao Zongxi Shi Zhihai Lin Zhemin Jiao Peirong Zhang Guihong | 2014 | Animal Husbandry and Feed Science2014，6，2： | 0 |
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