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14篇 您的检索式：作者名="Pardy R L"

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		题名	作者	年代	出处	被引量
	1	Gastro 2013 AP- DW/WCOG Shanghai Working Party Report:Chronic diar- rhea: Definition, classification, diagnosis 显示文摘	Schiller L R Pardi D S Robin S	2014	Journal of Gastroenterology & Hepatology2014，29，1：	1
	2	Evolution of the Kdo2-1ipid A biosynthesis in bacteria 显示文摘	Opiyo S O Pardy R L Moriyama H	2010	BMC Evolution Biology2010，10，：	1
	3	Regultory mechanism in leukocyte ad-hesion: flexible receptors for sophisticated travelers显示文摘	lmverard L Bender J R	1992	Immunol Today1992，，：	1
	4	Regulatory mechanisms in leukocyteadhesion:flexible receptors for sophisticated travelers显示文摘	Pardi R Inverardi L Bender JR	1992	Immunol Today1992，13，：	1
	5	Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions显示文摘	Hansen M R Mueller L Pardi A	1998	Nature Struc Biol1998，5，：	1
	6	Requlatory Mechanisms in Leukocyte Adhesion: Flexible Receptors for Sophisticated Travelers显示文摘	Pardi R Inverardi L Bender JR	1992	Immunol Today1992，13，6：	1
	7	Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions 显示文摘	Hansen M R Mueller L Pardi A	1998	Nat Struct Biol1998，5，12：	1
	8	Evolution of the Kdo2-1ipid A biosynthesis in bacteria 显示文摘	Opiyo S O Pardy R L Moriyama H	2010	BMC Evol Biol2010，10，：	1
	9	The effects of inspiratory muscle training in patients with cystic fibrosis显示文摘	ASHER M I PARDY R L COATES A L	1982	Am Rev Respir Dis1982，126，5：	1
	10	The effects of inspiratory muscle training on exercise per- formance in chronic airflow limitation显示文摘	Pardy R L Rivington R N Despas P J	1981	Am Rev Re- spir Dis1981，123，41：	1
	11	Ventilatory muscle training显示文摘	LEITH D E	1984	Respir Care1984，29，：	1
	12	The effects of inspiratory muscle training on exercise performance in chronic airflow limitation显示文摘	PARDY R L RIVINGTON R N DESPAS P J	1981	Am Rev Respir Dis1981，，41：	1
	13	Inspira- tory muscle training compared with physiotherapy in patients with chronic airflow limitation显示文摘	PARDY R L RIVINGTON R N DESPAS P J	1981	Am Rev Respir Dis1981，，41：	1
	14	Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury显示文摘Efficient in vivo delivery of anti-inflammatory proteins to modulate the microenvironment of an injured spinal cord and promote neuroprotection and functional recovery is a great challenge.Nucleoside-modified messenger RNA(mRNA)has become a promising new modality that can be utilized for the safe and efficient delivery of therapeutic proteins.Here,we used lipid nanoparticle(LNP)-encapsulated human interleukin-10(hIL-10)-encoding nucleoside-modified mRNA to induce neuroprotection and functional recovery following rat spinal cord contusion injury.Intralesional administration of hIL-10 mRNA-LNP to rats led to a remarkable reduction of the microglia/macrophage reaction in the injured spinal segment and induced significant functional recovery compared to controls.Furthermore,hIL-10 mRNA treatment induced increased expression in tissue inhibitor of matrix metalloproteinase 1 and ciliary neurotrophic factor levels in the affected spinal segment indicating a time-delayed secondary effect of IL-105 d after injection.Our results suggest that treatment with nucleoside-modified mRNAs encoding neuroprotective factors is an effective strategy for spinal cord injury repair.	LászlóGál Tamás Bellák Annamária Marton Zoltán Fekécs Drew Weissman Dénes Török Rachana Biju Csaba Vizler Rebeka Kristóf Mitchell B.Beattie Paulo J.C.Lin Norbert Pardi Antal Nógrádi Krisztián Pajer	2023	Research2023，，4：	0

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