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| 1 | Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery显示文摘AIM To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.METHODS This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy(RG), laparoscopic gastrectomy(LG), open gastrectomy(OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.RESULTS The present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients(RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative blood loss was significantly lower in the LG(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG(27.78 ± 11.45), LG(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay(P < 0.0001). A similar complications rate was found(P = 0.13). The leakage rate was not different(P = 0.78) between groups.CONCLUSION Laparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery. | Amilcare Parisi Daniel Reim Felice Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Alimoglu Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Olivier Facy Steven T Brower Zhi-Wei Jiang Lu Zang Arda Isik Alessandro Gemini Stefano Trastulli Alexander Novotny Alessandra Marano Tong Liu Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzolini Metin Leblebici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，13： | 17 |
| 2 | New totally intracorporeal reconstructive approach after robotic total gastrectomy: Technical details and short-term outcomes显示文摘AIM To show outcomes of our series of patients that underwent a total gastrectomy with a robotic approach and highlight the technical details of a proposed solution for the reconstruction phase.METHODS Data of gastrectomies performed from May 2014 to October 2016, were extracted and analyzed. Basic characteristics of patients, surgical and clinical outcomes were reported. The technique for reconstruction(Parisi Technique) consists on a loop of bowel shifted up antecolic to directly perform the esophago-enteric anastomosis followed by a second loop, measured up to 40 cm starting from the esojejunostomy, fixed to the biliary limb to create an enteroenteric anastomosis. The continuity between the two anastomoses is interrupted just firing a linear stapler, so obtaining the Roux-en-Y by avoiding to interrupt the mesentery.RESULTS Fifty-five patients were considered in the present analysis. Estimated blood loss was 126.55 ± 73 m L, no conversions to open surgery occurred, R0 resections were obtained in all cases. Hospital stay was 5(3-17) d, no anastomotic leakage occurred. Overall, a fast functional recovery was shown with a median of 3(3-6) d in starting a solid diet.CONCLUSION Robotic surgery and the adoption of a tailored reconstruction technique have increased the feasibility and safety of a minimally invasive approach for total gastrectomy. The present series of patients shows its implementation in a western center with satisfying short-term outcomes. | Amilcare Parisi Francesco Ricci Alessandro Gemini Stefano Trastulli Roberto Cirocchi Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，23： | 4 |
| 3 | Fluorescence image-guided lymphadenectomy using indocyanine green and near infrared technology in robotic gastrectomy显示文摘In recent years, some researchers have tried to find a way to improve the surgical identification of the lymphatic drainage routes and lymph node stations during radical gastrectomy, thus starting a new research frontier in this field called 'navigation surgery'. Among the different reported solutions, the introduction of the indocyanine green(ICG) has drawn attention for its characteristics, a fluorescence dye that can be detected in the near infrared spectral band(NIR). A fluorescence imaging technology has been integrated in the latest version of the Da Vinci robotic system and surgeons have extensively reported their experiences in colorectal and hepato-biliary surgery for tumors, vascular and lymphatic structures visualization. However, up to date, the combined use of fluorescence imaging and robotic technology has not been adequately investigated during lymphadenectomy in gastric cancer. | Jacopo Desiderio Stefano Trastulli AlessANDro Gemini Domenico Di Nardo Giorgio Palazzini Amilcare Parisi Vito D'ANDrea | 2018 | Chinese Journal of Cancer Research2018，30，5： | 3 |
| 4 | In vitro activity and fecal concentration of rifaximin after oral administration显示文摘 | Jiang ZD Ke S Palazzini E | 2000 | Antimicrob Agents Chemother2000，44，8： | 1 |
| 5 | In vitro activity and fecal concentration of rifaximin after oral administration显示文摘 | Jiang ZD Ke S Palazzini E | 2000 | Antimicrob Agents Chemothe2000，44，8： | 1 |
| 6 | Potential biocontrol agents for Fusarium head blight anddeoxynialenol production in wheat显示文摘 | Palazzini J M Ramirez M L Torres A M | 2007 | Crop Protection2007，26，11： | 1 |
| 7 | Pulmonary hypertension in primary Sj?gren’s syndrome: report of a case and review of the literature显示文摘 | M. Bertoni L. Niccoli G. Porciello L. Storri C. Nannini A. Manes M. Palazzini N. Galiè F. Cantini | 2005 | Clinical Rheumatology2005，，4： | 1 |
| 8 | Management of pulmonary arterial hypertension associated with con- genital systemic-to-pulmonary shunts and Eisen- mengers syndrome显示文摘 | Galie N Manes A Palazzini M | 2008 | Drugs2008，68，8： | 1 |
| 9 | In vitro activity and fecal concentration of rifaximin after oral administration显示文摘 | Jiang ZD Ke S Palazzini E | 2000 | Antimicrob Agent Chemother2000，44，： | 1 |
| 10 | Osteocyte differentiation in the tibia of newborn rabbit:an ultrastructural study of the formation of cytoplasmic processes显示文摘 | Palumbo C Palazzini S Zaffe D | 1990 | Acta Anat(Basel)1990，137，4： | 1 |
| 11 | In vitro activity and fecal concentration of fifaximin after oral administration 显示文摘 | JIABG ZD KE S PALAZZINI E | 2000 | Antimicrob Agents Chemother2000，44，8： | 1 |
| 12 | Biocontrol and population dynamics of Fusarium spp on wheat stubble in Araentina显示文摘 | Palazzini J M Groenenboom H B H Torres A M | 2012 | Plant Pathology2012，62，4： | 1 |
| 13 | Current era survival of patients with pulmonary arterial hypertension associated with congenital heart disease: a comparison between clinical subgroups 显示文摘 | Manes A Palazzini M Leci E | 2014 | Eur Heart J2014，35，： | 1 |
| 14 | Management of pulmo nary arterial hypertension associated with congenital systemic to pulmonary shunts and Eisenmengerls syndrome 显示文摘 | Galie N Manes A Palazzini M | 2008 | Drugs2008，68，10： | 1 |
| 15 | Morphological study of intercellular junctions during osteocyte differentiation显示文摘 | Palumbo C Palazzini S Marotti G | 1990 | Bone1990，11，6： | 1 |
| 16 | Management of pulmonary arterial hypertension associated with congenital systemic-to-pulmonary shunts and Eisenmenger 's syn- drome 显示文摘 | Galie N Manes A Palazzini M | 2008 | Drugs2008，68，8： | 1 |
| 17 | Current therapeutic approaches to pulmonary arterial hypertension显示文摘 | Galiè N Palazzini M Leci E | | 0，，06： | 1 |
| 18 | Critical evaluation of the variants influencing the clinical response of vitiligo : study of 60 cases treated with ultraviolet B narrow-band phototherapy 显示文摘 | Brazzelli V Antominetti M Palazzini S | 2007 | J Eur Acad Dermatol Venereol2007，21，10： | 1 |
| 19 | Management of pulmonary arterial hypertension associated with congenital systemic - to - pulmonary shunts and Eisenmenger's syndrome显示文摘 | Galie N Manes A Palazzini M | 2008 | Drugs2008，68，8： | 1 |
| 20 | Management of pulmonary arterial hypertension associated with congenital systemic-to- pulmonary shunts and Eisenmenger's syndrome显示文摘 | Galie N Manes A Palazzini M | 2008 | Drugs2008，68，： | 1 |
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