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18篇 您的检索式：作者名="POBLET E"

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		题名	作者	年代	出处	被引量
	1	Expression of HER2 and bradykinin B_1 receptors in precursor lesions of gallbladder carcinoma显示文摘AIM:To determine the expression of HER2 and bradykinin B 1 receptors(B 1 R) in the two pathogenic models of gallbladder cancer:the metaplasia-dysplasia-carcinoma and the adenoma-carcinoma pathways.METHODS:Receptor proteins were visualized by immunohistochemistry on 5-μm sections of paraffin-embedded tissue.Expression of both receptors was studied in biopsy samples from 92 patients(6 males and 86 females;age ranging from 28 to 86 years,mean 56 years).High HER2 expression in specimens was additionally investigated by fluorescence in situ hybridiza-tion.Cell proliferation in each sample was assessed by using the Ki-67 proliferation marker.RESULTS:HER2 receptor protein was absent in adenomas and in normal gallbladder epithelium.On the contrary,there was intense staining for HER2 on the basolateral membrane of epithelial cells of intestinal metaplasia(22/24;91.7%) and carcinoma in situ(9/10;90%),the lesions that displayed a significantly high proliferation index.Protein up-regulation of HER2 in the epithelium with metaplasia or carcinoma in situ was not accompanied by HER2 gene amplification.A similar result was observed in invasive carcinomas(0/12).The B 1 R distribution pattern mirrored that of HER2 except that B 1 R was additionally observed in the adenomas.The B 1 R appeared either as cytoplasmic dots or labeling on the apical cell membrane of the cells composing the epithelia with intestinal metaplasia(24/24;100%) and carcinoma in situ(10/10;100%) and in the epithelial cells of adenomas.In contrast,both HER2(4/12;33%) and B 1 R(1/12;8.3%) showed a low expression in invasive gallbladder carcinomas.CONCLUSION:The up-regulation of HER2 and B1R in precursor lesions of gallbladder carcinoma suggests cross-talk between these two receptors that may be of importance in the modulation of cell proliferation in gallbladder carcinogenesis.	Cesar Toledo Carola E Matus Ximena Barraza Pamela Arroyo Pamela Ehrenfeld Carlos D Figueroa Kanti D Bhoola Maeva del Pozo Maria T Poblete	2012	World Journal of Gastroenterology2012，18，11：	6
	2	Primary adenoid cystic carcinoma of the mandible: case re- port and review of the literature显示文摘	Garcia de Marcos JA Calder6n-Polanco J Poblet E	2008	J Oral Maxillofac Surg2008，66，12：	1
	3	Different immunoreactivity of endothelial markers in well and poorly differentiated areas of angiosarcomas显示文摘	Poblet E Gonzalez-Palacios F Jimenez FJ	1996	Virchows Arch1996，428，45：	1
	4	The immunohistochemical expression of CD34 in human hair follicles:a comparative study with the bulge marker CK15显示文摘	POBLET E JIMéNEZ F GODíNEZz J M	2006	Clin Exp Dermatol2006，31，6：	1
	5	The Arrector Pili Muscle and the Follicular Unit of the Scalp:A Microscopic Anatomy Study显示文摘	Poblet E Ortega F Jimenez F	2002	Dermatol Surg2002，28，9：	1
	6	Different im- munoreaetivity of endothelial markers in well and poorly differentiated areas of angiosarcomas 显示文摘	Poblet E Gonzalez-Palacios F Jimenez FJ	1996	Virchows Arch1996，428，45：	1
	7	Molecular cloning of IGF-I and IGF-I receptor and their expression pattern in the Chilean flounder (Paralichthys adspersus) 显示文摘	Escobar S Fuentes E N Poblete E	2011	Comp Biochem Physiol B Biochem Mol Biol2011，159，3：	1
	8	Submicron copper-low-density polyethylene conducting composites:Structural electrical,and percolation threshold显示文摘	ALVAREZ M P POBLETE V H PILLEUX M E	2006	Journal of Applied Polymer Science2006，99，6：	1
	9	Photocatalytic degradation of humic acids and landfill leachate using a solid industrial by-product containing TiOz and Fe 显示文摘	Poblete R Otal E Vilches LF	2011	Appl Catal B2011，102，：	1
	10	Adler- JP : Clonidine-induced nitric oxide-dependent vasorelaxation mediated by endothelial alpha (2)-adrenoceptor activation 显示文摘	Figueroa X F Poblete M I Graschinsky E Huidobro-Toro Boric M P	2001	Br J Pharmacol2001，134，5：	1
	11	Single port access (SPA)cholecystectomy: a completely transumbil- ical approach显示文摘	Podolsky E R Rottman S J Poblete H	2009	J Laparoendosc Adv Surg Tech A2009，19，2：	1
	12	The arrector pili muscle and the follicular unit of the scalp : a mi-croscopic anatomy study 显示文摘	Poblet E Oega F Jimenez F	2002	DermatolSurg2002，28，9：	1
	13	Frontal fibrosing alopecia versus lichen planopilaris: a clinicopathologieal study显示文摘	Poblet E Jimenez F Pascual A	2006	Interna- tional Journal of Dermatology2006，45，4：	1
	14	The immunohistochemical expression of CD34 in human hair follicles:a comparative study with the bulge marker CK15显示文摘	POBLET E JIMENEZ F GODINEZ J M etal	2006	Clin Exp Dermatol2006，31，6：	1
	15	Identification of acetic acid bacteria by restriction fragment length polymorphism analysis of a PCR-amplified fragment of the gene coding for 16S rRNA显示文摘	POBLET M ROZ(E)S N GUILLAM(O)N J M	2000	Lett Appl Microbiol2000，31，1：	1
	16	Methyl jas-monate treatment induces changes in fruit ripening by modifyingthe expression of several ripening genes in FragaHa chiloensis fmit显示文摘	CONCHA C M FIGUEROA N E Poblete LA	2013	Plant Physiol Biochem2013，9，70：	1
	17	Molecular cloning of IGF-1and IGF-1receptor and their expression pattern in the Chilean flounder(Paralichthys adspersus)显示文摘	Escobar S Fuentes EN Poblete E	2011	Comp Biochem Physiol B Biochem Mol Biol2011，159，3：	1
	18	Photocatalytic degradation of humic acids and landfill leachate using a solid industrial by-pro- duct containing TiO2 and Fe 显示文摘	Poblete R Otal E Vilches L F	2011	Applied Catalysis B : Environmen- tal2011，102，12：	1

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