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| 1 | Diagnosis of interatrial block显示文摘 | Antoni Bay, s de Luna Adrian Baranchuk Luis Alberto Escobar Robledo Albert Masso van Roessel Manuel Martinez-Selles | 2017 | Journal of Geriatric Cardiology2017，14，3： | 6 |
| 2 | T_3-induced liver AMP-activated protein kinase signaling:Redox dependency and upregulation of downstream targets显示文摘AIM:To investigate the redox dependency and promotion of downstream targets in thyroid hormone(T3)-induced AMP-activated protein kinase(AMPK)signaling as cellular energy sensor to limit metabolic stresses in the liver.METHODS:Fed male Sprague-Dawley rats were given a single ip dose of 0.1 mg T3/kg or T3 vehicle(Na OH0.1 N;controls)and studied at 8 or 24 h after treatment.Separate groups of animals received 500 mg N-acetylcysteine(NAC)/kg or saline ip 30 min prior T3.Measurements included plasma and liver 8-isoprostane and serumβ-hydroxybutyrate levels(ELISA),hepaticlevels of m RNAs(q PCR),proteins(Western blot),and phosphorylated AMPK(ELISA).RESULTS:T3 upregulates AMPK signaling,including the upstream kinases Ca2+-calmodulin-dependent protein kinase kinase-βand transforming growth factor-β-activated kinase-1,with T3-induced reactive oxygen species having a causal role due to its suppression by pretreatment with the antioxidant NAC.Accordingly,AMPK targets acetyl-Co A carboxylase and cyclic AMP response element binding protein are phosphorylated,with the concomitant carnitine palmitoyltransferase-1α(CPT-1α)activation and higher expression of peroxisome proliferator-activated receptor-γco-activator-1αand that of the fatty acid oxidation(FAO)-related enzymes CPT-1α,acyl-Co A oxidase 1,and acylCo A thioesterase 2.Under these conditions,T3 induced a significant increase in the serum levels ofβ-hydroxybutyrate,a surrogate marker for hepatic FAO.CONCLUSION:T3 administration activates liver AMPK signaling in a redox-dependent manner,leading to FAO enhancement as evidenced by the consequent ketogenic response,which may constitute a key molecular mechanism regulating energy dynamics to support T3preconditioning against ischemia-reperfusion injury. | Luis A Videla Virginia Fernández Pamela Cornejo Romina Vargas Paula Morales Juan Ceballo Alvaro Fischer Nicolás Escudero Oscar Escobar | 2014 | World Journal of Gastroenterology2014，20，46： | 3 |
| 3 | Growth of CrN,films by DC reactive magnetron sputtering at constant N2/Ar gas flow显示文摘 | Forniés E Escobar Galindo R Sánchez O | 2006 | Surface & Coatings Technology2006，200，： | 1 |
| 4 | High-throughput viral expression of cDNA-green fluorescent protein fusions reveals novel subcellular addresses and identifies unique proteins that interact with plasmodesmata 显示文摘 | ESCOBAR N M HAUPT S THOW G | 2003 | The Plant Cell2003，15，： | 1 |
| 5 | High-throughput viral expression of cDNA-green fluorescent protein fusions reveals novel subcellular addresses and identifies unique proteins that interact with plasmodesmata显示文摘 | Escobar N M Haupt S Thow G | 2003 | Plant Cell2003，15，： | 1 |
| 6 | Novel robotic da Vinci instruments for lap aroendoscopic single-site surgery显示文摘 | Haber G P White M A Autorino R Escobar P F Kroh M D Chalikonda S | 2010 | Urology2010，76，： | 1 |
| 7 | Bacterial growth in distri- bution systems Effect of assimilable organic carbon and biode- gradable dissolved organic carbon显示文摘 | Escobar I C Randall A A Taylor J S | 2001 | Environmental Science -Technology2001，35，17： | 1 |
| 8 | Increased prevalence of gestational diabetes mellitus among women with diagnosed polycystic ovary syndrome: A population-based study 显示文摘 | Lo J C Feigenbaum S L Escobar G J | 2006 | Diabetes Care2006，29，： | 1 |
| 9 | Cyclooxygenase-2 and hypoxia-regulated proteins are modulated by basic fibroblast growth factor in acute renal failure显示文摘 | Villanueva S Escobar P JacubovskyI etal | 2012 | Biol Res2012，45，1： | 1 |
| 10 | Determination of aflatoxins B1 in food and feedstuffs in Cuba using a immunoenzymatic regent kit显示文摘 | Escobar A Regueiro O S | 2002 | Journal of Food protection2002，65，： | 1 |
| 11 | The effect of alumina on FCC catalyst in the presence of nickel and vanadium显示文摘 | Pinto F V Escobar A S Oliveira de B G | 2010 | AppliedCatalysis A: General2010，388，12： | 1 |
| 12 | Removal of assimilable organic carbon and biodegradable dissolved organic carbon by reverse osmosis and nanofiltration membranes 显示文摘 | ESCOBAR I C HONG S RANDALL A A | 2000 | Membr Sci2000，175，： | 1 |
| 13 | The changing role of maternal thyroid hormone in fetal brain development显示文摘 | de Escobar GM Ares S Berbel P | 2008 | Semin Perinatol2008，32，6： | 1 |
| 14 | Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity:possible role in cardioprotection显示文摘 | Sánchez G Escobar M Pedrozo Z | 2008 | Cardiovasc Res2008，77，2： | 1 |
| 15 | Biofuels~en- vironment,technology and food security显示文摘 | ESCOBAR J C LORA E S VENTURINI O J | 2009 | Renewable and Sus- tainable Energy Reviews2009，13，67： | 1 |
| 16 | Light regulation of the Arabidopsis respiratory chain multiple discrete photoreceptor responses contribute to induction of type II NAD(P) H dehydrogenase genes显示文摘 | Escobar M A Franklin K A Svensson A S | 2004 | Plant Physiology2004，136，： | 1 |
| 17 | Synthesis of acid protease from Mucor miehei integration of production and recovery显示文摘 | J Escobar S Barenett | 1995 | Process Biochemistry1995，30，8： | 1 |
| 18 | Photosyntheticelectron transport regulates the expression of cytosolic ascorbateperoxidase genes in Arabidopsis during excess light stress显示文摘 | KARPINSKI S ESCOBAR C KARPINSKA B | 1997 | ThePlant Cell Online1997，9，4： | 1 |
| 19 | Increased p revalenceof gestational diabetes mellitus among women with diagnosedpolycystic ovary syndrome:A population2based study显示文摘 | LoJC Feigenbaum S L Escobar G J | 2006 | D iabetesCare2006，29，19： | 1 |
| 20 | Structure function studies of human flt3 ligand显示文摘 | Escobar S Brasel K Anderberg R | 1995 | Blood1995，，： | 1 |
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