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209篇 您的检索式:作者名="PHILIP J L"
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1Predictors of suboptimal bowel preparation in asymptomatic patients undergoing average-risk screening colonoscopy显示文摘AIM To identify risk factors for a suboptimal preparation among a population undergoing screening or surveillance colonoscopy.METHODS Retrospective review of the University of Michigan and Veteran's Administration(VA) Hospital records from 2009 to identify patients age 50 and older who underwent screening or surveillance procedure and had resection of polyps less than 1 cm in size and no more than 2 polyps. Patients with inflammatory bowel disease or a family history of colorectal cancer were excluded. Suboptimal procedures were defined as procedure preparations categorized as fair, poor or inadequate by the endoscopist. Multivariable logistic regression was used to identify predictors of suboptimal preparation.RESULTS Of 4427 colonoscopies reviewed, 2401 met our inclusion criteria and were analyzed. Of our population, 16% had a suboptimal preparation. African Americans were 70% more likely to have a suboptimal preparation(95%CI: 1.2-2.4). Univariable analysis revealed that narcotic and tricyclic antidepressants(TCA) use, diabetes, prep type, site(VA vs non-VA), and presence of a gastroenterology(GI) fellow were associated with suboptimal prep quality. In a multivariable model controlling for gender, age, ethnicity, procedure site and presence of a GI fellow, diabetes [odds ratio(OR) = 2.3; 95%CI: 1.6-3.2], TCA use(OR = 2.5; 95%CI: 1.3-4.9), narcotic use(OR = 1.7; 95%CI: 1.2-2.5) and Miralax-Gatorade prep vs 4L polyethylene glycol 3350(OR = 0.6; 95%CI: 0.4-0.9) were associated with a suboptimal prep quality. CONCLUSION Diabetes, narcotics use and TCA use were identified as predictors of poor preparation in screening colonoscopies while Miralax-Gatorade preps were associated with better bowel preparation.Shail M Govani Eric E Elliott Stacy B Menees Stephanie L Judd Sameer D Saini Constantinos P Anastassiades Annette L Urganus Suzanna J Boyce Philip S Schoenfeld 2016World Journal of Gastrointestinal Endoscopy2016,8,17:7
2Preoperative immunonutrition in patients undergoing liver resection:A prospective randomized trial显示文摘BACKGROUND Preoperative supplementation with immunonutrients, including arginine and n-3 fatty acids, has been shown in a number of systematic reviews to reduce infectious complications in patients who have undergone gastrointestinal surgery. Limited information, however, is available on the benefits of nutritional supplementation enriched with arginine and n-3 fatty acids in patients undergoing liver resection.AIM To evaluate the effects of preoperative nutritional supplementation enriched with arginine and n-3 fatty acids on inflammatory and immunologic markers and clinical outcome in patients undergoing liver resection.METHODS Thirty-four patients undergoing liver resection were randomized to either five days of preoperative Impact? [1020 kcal/d, immunonutrition(IMN) group], or standard care [no supplementation, standard care(STD) group]. Nutritional status was measured at study entry by subjective global assessment(SGA).Functional assessments(grip strength, fatigue and performance status) were carried out at study entry, on the day prior to surgery, and on postoperative day(POD) 7 and 30. Inflammatory and immune markers were measured at study entry, on the day prior to surgery, and POD 1, 3, 5, 7, 10 and 30. Postoperative complications were recorded prospectively until POD30.RESULTS A total of 32 patients(17 IMN and 15 STD) were analysed. All except four patients were SGA class A. The plasma ratio of(eicosapentaenoic acid plus docosahexaenoic acid) to arachidonic acid was higher in IMN patients on the day prior to surgery and POD 1, 3, 5 and 7(P < 0.05). Plasma interleukin(IL)-6 concentrations were elevated in the IMN group(P = 0.017 for POD7). No treatment effect was detected for functional measures, immune response(white cell count and total lymphocytes) or markers of inflammation(C-reactive protein,tumour necrosis factor-α, IL-8, IL-10). There were 10 patients with infectious complications in the IMN group and 4 in the STD group(P = 0.087). Median hospital stay was 9(range 4–49) d in the IMN group and 8(3-34) d in the STD group(P = 0.476).CONCLUSION In well-nourished patients undergoing elective liver resection, this study failed to show any benefit of preoperative immunonutrition.Kylie Russell Han-Guang Zhang Lyn K GillANDers Adam SJR Bartlett Helena L Fisk Philip C Calder Peter J Swan Lindsay D Plank 2019World Journal of Hepatology2019,11,3:3
3Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion显示文摘Philip N Newsome Ingolfur Johannessen Shelagh Boyle Evangelos Dalakas Karen A Mcaulay Kay Samuel Frances Rae Lesley Forrester Marc L Turner Peter C Hayes David J Harrison Wendy A Bickmore John N Plevris 2003Gastroenterology2003,,7:2
4Bioremediation of chromium contaminated soil: optimization of operating parameters under laboratory conditions显示文摘Jeyasingh J Philip L 2005Journal of Hazardous Materials2005,118,13:1
5Institutional repositories: evaluating the reasons for non-use of Comell University's Installation of DSpaee 显示文摘Philip M D Matthew J L 2007D-Lib Magazine2007,13,34:1
6Solvent-free oxidation of primary alcohols to aldehydes using Au-Pd/TiO2 catalysts显示文摘Enache D I Edwards J K Philip L 2006Science2006,311,:1
7Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson’s disease: an open-label, phase I trial显示文摘William J Marks Jill L Ostrem Leonard Verhagen Philip A Starr Paul S Larson Roy AE Bakay Robin Taylor Deborah A Cahn-Weiner A Jon Stoessl C Warren Olanow Raymond T Bartus 2008Lancet Neurology2008,,5:1
8An introduction toevaluating biometric systems显示文摘Philips P J martin A Wilson C L Computer0,32,2:1
9Staging of carcinoid tumours with 18 F-DOPA PET: a prospective, diagnostic accuracy study显示文摘Klaas P Koopmans Elisabeth GE de Vries Ido P Kema Philip H Elsinga Oliver C Neels Wim J Sluiter Anouk NA van der Horst-Schrivers Pieter L Jager 2006Lancet Oncology2006,,9:1
10Simple shearing flows inPolyisobutylene solutions 显示文摘Zapas L J Philips J C 1971Journal of ResearchNational Bureau Standards1971,75,1:1
11Effect of fat replacers on the sensory properties, colour, melting, and hardness of ice cream显示文摘Rland A M Philips L G Brook J 1999Journal of Dairy science1999,82,:1
12The growth of Mg(OH)2 crystals from MgCl2 and Ca(OH)2 in a brine environment显示文摘Philips V A Kolbe J L Opperharser H 1997Journal of Crystal Growth1997,41,:1
13RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX显示文摘Jennifer S Michaelson J S Philip L 2003Cell Science2003,116,:1
14Clinical review:biomarkers of acute kidney injury:where are we now?显示文摘Ostermann M Philips B J Forni L G 2012Critical Care2012,16,5:1
15The Contribution of Molecular Biology to the Development of Vaccines Against Nematode and Trematode Parasites of Domestic Ruminants显示文摘David P Knox Diane L Redmond Philip J Skuce 2001Veterinary Parasitology2001,101,34:1
16Reduced order modeling of an elastic panel in transonic flow 显示文摘David J Lucia Philip S Beran Paul L King 2002AIAA2002,1594,:1
17Problems of clay desiccation in composite lining systems显示文摘Hewitt P J Philip L K 0,,53:1
18Calcitonin and insulin in isobutylcyanoacrylate nanocap sules: protection against proteases and effect on intestinal absorption in rats显示文摘PHILIP J L CATHY S T 1994J Pharm Pharmacol1994,46,:1
19Reactivity of heat treated coals in air at 500 ℃ 显示文摘ROBERT G J SATYENDRA P N PHILIP L W J 1973Fuel1973,52,4:1
20Assessment of Hypertensive Target Organ Damage 显示文摘Joseph L Izzo J Philip R 2007Hypertension (First Edition)2007,,:1
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