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30篇 您的检索式:作者名="Osipo"
    题名 作者 年代 出处 被引量
1Cancer stem cells and HER2 positive breast cancer:The story so far显示文摘Human Epidermal Growth Factor Receptor type 2(HER2)gene amplification and/or protein overexpression is observed in patients suffering from HER2t breast cancer.This subtype of breast cancer has improved prognosis due to availability of anti-HER2 therapy.However,drug resistance and tumor recurrence still remains a major concern.Cancer Stem Cells(CSCs)are believed to constitute the subset of cell population that is resistant to drug treatment and possesses characteristics of stem cells.CSCs enable the tumors to thrive despite major insults.This review provides a comprehensive idea about the concept of CSCs in context of HER2t breast cancer by providing the description of the markers that are used for the identification of CSCs and by elucidating the signaling pathways that are associated with HER2t breast CSCs.Furthermore,the review also describes the interaction of HER2 with those signaling pathways and the future of targeting CSCs in HER2t breast cancer.Deep Shah Clodia Osipo 2016Genes & Diseases2016,3,2:3
2Rational targeting of Notchsignaling in cancer 显示文摘Rizzo P Osipo C Foreman K 2008Oncogene2008,27,38:1
3Rational targeting of Notch signaling in cancer显示文摘Rizzo P Osipo C Foreman K 2008Oncogene2008,27,38:1
4ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor 显示文摘Osipo C Patel P Rizzo P 2008Oncogene2008,27,37:1
5Off the beaten path- way:the complex cross talk between Notch and NF-kappaB 显示文摘OSIPO C GOLDE T E OSBORNE B A 2008Lab Invest2008,88,1:1
6Notch-EGFR/HER2 Bidirectional Crosstalk in Breast Cancer 显示文摘Baker AT Zlobin A Osipo C 2014Front oncol2014,4,3:1
7ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor显示文摘Osipo C Patel P Rizzo P 2008Oncogene2008,27,37:1
8Notch-1 activates es-trogen receptor-alpha-dependent transcription via IKKal-pha in breast cancer cells显示文摘HAO L RIZZO P OSIPO C 2010Oncogene2010,29,2:1
9Notch-1 activates estrogen re- ceptor-alpha-dependent transcription via IKKalpha in breast cancer cells显示文摘Hao L Rizzo P Osipo C 2010Oncogene2010,29,2:1
10The liquefaction of layey soils under cylic loading 显示文摘Gratchev I B Sassa K Osipo V 2006Engineering Geo-lo- y2006,86,1:1
11Rational targeting of Notch signa- ling in cancer显示文摘Rizzo P Osipo C Foreman K 2008Oncngene2008,27,38:1
12Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation显示文摘Lewis JS Meeke K Osipo C 0,,23:1
13Trastuzumab resistance: role for Notch signaling 显示文摘Mehta K Osipo C 2009ScientificWoddJoumal2009,9,:1
14Hedgehog sjgnaling in hepatocellular carcinoma:novel therapeutic strategy targeting hedgehog signaling in HCC显示文摘Osipo C Miele L 2006Cancer Biol Ther2006,5,2:1
15Gamma secretase in- hibitors of Notch signaling显示文摘Olsanskas- Kuprys R Zlobin A Osipo C 2013OncoTargets and therapy2013,6,:1
16ERB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to garnma-secretase inhibitor 显示文摘Osipo C Patel P Rizzo P 2008Oneongene2008,27,37:1
17Off the beaten pathway: the complex cross talk between Notch and NF-kappaB显示文摘Osipo C Golde T E Osborne B A 2008Lab Invest2008,88,1:1
18ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor显示文摘Osipo C Patel P Rizzo P 2008Oncogene2008,27,37:1
19Trastuzumab therapy for tamoxifenstimulated endometrial cancer显示文摘Osipo C Meeke K Liu H 2005Cancer Res2005,65,18:1
20The apoptotic action of estrogen following exhaustive antihormonal therapy:a new clinical treatment strategy显示文摘Jordan V C Lewis J S Osipo C 2005Breast2005,14,6:1
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