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952篇 您的检索式：作者名="Ohlsson"

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	题名	作者	年代	出处	被引量
1	NOTUM inhibition increases endocortical bone formation and bone strength显示文摘The disability,mortality and costs caused by non-vertebral osteoporotic fractures are enormous.Existing osteoporosis therapies are highly effective at reducing vertebral but not non-vertebral fractures.Cortical bone is a major determinant of non-vertebral bone strength.To identify novel osteoporosis drug targets,we phenotyped cortical bone of 3 366 viable mouse strains with global knockouts of druggable genes.Cortical bone thickness was substantially elevated in Notum?/?mice.NOTUM is a secreted WNT lipase and we observed high NOTUM expression in cortical bone and osteoblasts but not osteoclasts.Three orally active small molecules and a neutralizing antibody inhibiting NOTUM lipase activity were developed.They increased cortical bone thickness and strength at multiple skeletal sites in both gonadal intact and ovariectomized rodents by stimulating endocortical bone formation.Thus,inhibition of NOTUM activity is a potential novel anabolic therapy for strengthening cortical bone and preventing non-vertebral fractures.	Robert Brommage Jeff Liu Peter Voge Faika Mseeh Andrea Y.Thompson David G.Potter Melanie K.Shadoan Gwenn M.Hansen Sabrina Jeter-Jones Jie Cui Dawn Bright Jennifer P.Bardenhagen Deon D.Doree Sofia Moverare-Skrtic Karin H.Nilsson Petra Henning Ulf H.Lerner Claes Ohlsson Arthur T.Sands James E.Tarver David R.Powell Brian Zambrowicz Qingyun Liu	2019	Bone Research2019，7，1：	2
2	Ibuprofen for the treatment of patent ductus arteriosus in preterm and / or low birth weight infants 显示文摘	Ohlsson A Walia R Shah S	2005	Cochrane Database Syst Rev2005，19，00：	1
3	Thoughts beyond words:When language overshadows insight显示文摘	Ohlsson S Brook K	1993	Journal of Experimental Psychology:General1993，，：	1
4	Surgical versus medical treatment with cyclooxygenase inhibitors for symptomatic patent ductus arteriosus in preterm infants显示文摘	Malviya M Ohlsson A Shah S	2008	Cochrane Database Syst Rev2008，1，00：	1
5	Growth and the Public Sector: A critical review 显示文摘	Agell Jonas Thomas Lindh and Henry Ohlsson	1997	European Journal of Political Economy1997，，13：	1
6	Ibuprofen for the treatment ofpatent ductus arteriosus in preterm and for low birth weight infants显示文摘	Ohlsson A Walia R Shah SS	2010	Cochrane Database Syst Rev2010，14，00：	1
7	The role of liverderived insulin-like growth factor-Ⅰ显示文摘	Ohlsson C Mohan S Sj(o)gren K		0，，05：	1
8	Surgical versus medical treatment with cyclooxygenase inhibitors for symptomatic patent ductus arteriosus in preterm infants显示文摘	Malviya M Ohlsson A Shah S	2008	Cochrane Database Syst Rev2008，，00：	1
9	Macrophage stimulation using a group B-streptococcus exotoxin (CM101) leads to axonal regrowth in the injured optic nerve 显示文摘	Ohlsson M Mattsson P Wamil BD	2004	Restor Neurol Neurosci2004，22，：	1
10	High-sensitivity serum C-reactive protein levels in subjects with or without myocardial infarction or periodontitis显示文摘	Persson C R Pettersson T Ohlsson O	2005	J Clin Periodontol2005，32，11：	1
11	Screening metris of the Lang Ⅱ,Frisby,Randot,Titmus,and TNO stereo tests显示文摘	Ohlsson J Villarreal G Abrahamsson M	2001	JAAPOS2001，5，5：	1
12	Intravenous immunoglobulin for preventing infection in preterm and/or low-birth-weight infants显示文摘	Ohlsson A Lacy JB	2001	Cochrane Database Syst Rev2001，10，00：	1
13	IPF1, a homeodomain-containing transactivator of the insulin gene 显示文摘	Ohlsson H Karlsson K Edlund T	1993	EMBO J1993，12，11：	1
14	Bacterial profile and burden of periodontal infection in subjects with a diagnosis of acute coronary syndrome 显示文摘	Renvert S Pettersson T Ohlsson 0	2006	J Periodontol2006，77，7：	1
15	Growth and the Public Sector : a reply 显示文摘	Jonas Agell Thomas Lindh Henry Ohlsson	1999	European Journal of Political Economy1999，15，：	1
16	查看详情显示文摘	Bjork M T Ohlsson B J Sass T Peersson A I Thelander C Mag-nusson M H Deppert K Wallenberg L R Samuelson L		0，，：	1
17	Non-standard Hamiltonian effects on neutrino oscillations显示文摘	M. Blennow T. Ohlsson W. Winter	2007	The European Physical Journal C2007，，4：	1
18	Obesity and disturbed lipoprotein profile in estrogen receptor-alpha-deficient male mice显示文摘	OHLSSON C HELLBERG N PARINIP	2000	Biochem Biophys Res Commun2000，278，3：	1
19	Temperature distribution of microwaveheating spheres and cylinders显示文摘	Ohlsson T Risman P O	1978	Journal of Microwave Power and Electromagnetic Energy1978，13，4：	1
20	Inhaled versus systemic corticosteroids for preventing chronic lung disease in ventilated very low birth weight preterm neonats显示文摘	Shah SS Ohlsson A Halliday H	2003	Chochrane Database2003，，00：	1

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