|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of hepatic artery embolization on liver hypertrophy response in a rabbit liver VX2tumor model显示文摘BACKGROUND:Portal vein embolization not only induces hypertrophy of the non-embolized liver,but also enhances tumor growth.The latter could be prevented by embolizing the hepatic arteries supplying the tumor-bearing liver segments.This study aimed to determine the effects of transcatheter arterial embolization(TAE)on tumor volume and liver regeneration in a rabbit VX2 tumor model.METHODS:Twenty-three rabbits underwent subcapsular tumor implantation with a VX2 tumor.Two weeks after implantation,18 rabbits were used for TAE experiments,5were for sham controls.Tumor response and liver regeneration response of the embolized cranial and non-embolized caudal liver lobes were assessed by CT volumetry,liver to body weight index,and the amount of proliferating hepatocytes.RESULTS:All super-selective arterial tumor embolization procedures were performed successfully.Despite embolization,the tumor volume increased after an initial steady state.The tumor volume after embolization was smaller than that of the sham group,but this difference was not significant.Massive necrosis of the tumor,however,was seen after embolization,without damage of the surrounding liver parenchyma.There was a significant atrophy response of the tumor bearing cranial lobe after super-selective arterial embolization of the tumor with a concomitant hypertrophy response of the non-embolized,caudal lobe.This regeneration response was confirmed histologically by a significantly higher number of proliferating hepatocytes on the Ki-67 stained slides.CONCLUSIONS:Super-selective,bland arterial coil embolization causes massive necrosis of the tumor,despite increase of volume on CT scan.Atrophy of the tumor bearing liver lobe is seen after arterial embolization of the tumor with a concomitant hypertrophy response of the non-embolized lobe,despite absence of histological damage of the tumor-surrounding liver parenchyma. | Krijn P van Lienden Lisette T Hoekstra Jessica D van Trigt Joris J Roelofs Otto M van Delden Thomas M van Gulik | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，6： | 2 |
| 2 | Persistent immune activation in HIV-1 infection is associated with progression to AIDS显示文摘 | Hazenberg M D Otto S A van Benthem B H | 2003 | AIDS2003，17，： | 1 |
| 3 | Persistent immune activation in HIV-1 infection is associated with progression to AIDS显示文摘 | Hazenberg M D Otto S A van Benthem B H | 2003 | AIDS2003，17，： | 1 |
| 4 | Post- traumatic stress disorder symptoms following media exposure to tragic events: Impact of 9/11 on children at risk for anxiety disorders显示文摘 | Otto M W Henin A Hirshfeld- Becker D R | 2007 | Journal of Anxiety Disorders2007，21，7： | 1 |
| 5 | Discovery of recurrent KIF5B-RET fusions and other targetable alterations from clinical NSCLC specimens 显示文摘 | Capelletti M Lipson D Otto G | 2012 | J Clin Oncol2012，30，15： | 1 |
| 6 | Association of aortic valve sclerosis with cardiovascular mortality and morbidity in the elderly 显示文摘 | OTtO C M LIND B K KITZMAN D W | 1999 | N Engl J Med1999，341，1： | 1 |
| 7 | T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation:a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART)显示文摘 | Hazenberg M D Stuart J W Otto S A | 2000 | {H}Blood2000，，01： | 1 |
| 8 | transPalmitoleic acid,other dairy fat biomarkers,and incident diabetes:the multi-ethnic study of atherosclerosis(MESA)显示文摘 | D Mozaffarian M C d O Otto R N Lemaitre | 2013 | American Journal of Clinical Nutrition2013，97，4： | 1 |
| 9 | Biochemical and proteomic analysis of the magnetosome membrane in Magnetospitillum gryphiswaldense 显示文摘 | GRUNBERG K MULLER E C OTTO A RESZKA R LINDER D KUBE M REINHARDT R SCHULER D | 2004 | Applied and Environmental Microbiology2004，70，2： | 1 |
| 10 | High on/off ratios in bilayer graphene field effect transistors realized by sur?face dopants显示文摘 | Szafranek B N Schall D Otto M | 2011 | Nano Letters2011，11，7： | 1 |
| 11 | Detection of simulated interstitial lung disease and catheters with selenium, storage phosphor, and film-baseradiography 显示文摘 | Bernhardt T M Otto D Reichel G | 1999 | Radiology1999，213，2： | 1 |
| 12 | Ammonia,volatile fatty acids,phenolics and odour offensiveness in manure from growing pigs fed diets reduced in protein concentration显示文摘 | Otto M Yokoyama R D Bermuth T V | 2003 | Journal of Animal Science2003，81，： | 1 |
| 13 | Phase Ⅰ and Ⅱ enzymes and antioxidant responses in different tissues of brown bullheads from relatively polluted and non-polluted systems显示文摘 | OTTO D M MOON T W | 1996 | Arch Environ Contam Toxicol1996，31，1： | 1 |
| 14 | Genetic mapping offloral traits associated with reproductive isolation in rnonkeyfolw-ers ( Mimulus ) 显示文摘 | Bradshaw H D Wilbert S M Otto K G | 1995 | Nature1995，376，： | 1 |
| 15 | Adipose development: from stem cell to adipocyte显示文摘 | Tamara C Otto M Lane D | 2005 | Critical Reviews in Biochemistry and Molecular Biology2005，40，4： | 1 |
| 16 | Gene expression studies in kiwifruit and gene over-expression in Arabidopsis indicates that GDP-L-galactose guanyltransferase is a major control point of vitamin C biosynthesis显示文摘 | BULLEY S M RASSAM M HOSER D OTTO W SCHUNEMANN N WRIGHT M MACRAE E GLEAVE A LAING W | 2009 | Journal of Experimental Botany2009，60，3： | 1 |
| 17 | The eukaryotic-type serine/ threonine protein kinase Stk is required for biofilm formation and virulence in Staphylococcus epidermidis 显示文摘 | Liu Q Fan J Niu C Wang D Wang J Wang X Villaruz AlE Li M Otto M Gao Q | 2011 | PLoS One2011，6，9： | 1 |
| 18 | A pilot study of functional cognitive behavioral Therapy ( fCBT ) for schizophrenia 显示文摘 | Cather C Penn D Otto M | 2005 | Schizophr Res2005，74，： | 1 |
| 19 | Basic Fibroblast Growth Factor and Nerve Growth Factor Administered in Gel Foam Rescue Medial Septal Neurons After Fimbria Fornix Transaction显示文摘 | Otto D Frotscher M Unsicker K | 1989 | J Neurosci Res1989，22，1： | 1 |
| 20 | ALLENEOXIDE CYCLASE (AOC) gene family members of Arabidopsis thaliana : tissue-and organ-spe- cific promoter activities and in vivo heteromerization显示文摘 | IRENE S OTTO M CAROLIN D | 2012 | J Exp Bot2012，63，17： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员