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| 1 | Antioxidant, antimicrobial and cytotoxic potential of condensed tannins from Leucaena leucocephala hybrid-Rendang显示文摘Condensed tannins(CTs)are one of the promising compounds due to their potentially health-promoting qualities.In this study,CTs were extracted from a Leucaena leucocephala hybrid-Rendang and subjected to various biological studies including antioxidant(using Ferric reducing antioxidant power(FRAP),DPPH and ABTS radical scavenging assay),anti-microbial(against different pathogens)and cytotoxic activities(toward human breast adenocarcinoma(MCF-7),human colon carcinoma(HT29),human cervical carcinoma(HeLa)and human liver carcinoma(HepG2)cell lines)in cancer cells through in vitro experiments.The structural characteristics and purity of CTs extract were determined using 13C NMR.The results showed that CTs exhibited higher in vitro antioxidant activities(2257.12±80.55 mg TEAC/g extract,605.3±1.82 mg TEAC/g extract and 1014.03±1.20 mg TEAC/g extract in FRAP,ABTS and DPPH assay,respectively)and demonstrated anti-microbial activities toward selected Gram’s positive and Gram’s negative bacteria tested with MIC and MBC value at 6.25–50 mg/mL.Furthermore,among other selected cancer cells,CTs also demonstrated cytotoxic activity toward human breast cancer cells(MCF-7)(IC50=38.33±2.08mg/mL).Characteristic of apoptosis such as cell shrinkage,nuclear condensation and apoptotic bodies were shown in MCF-7.These preliminary investigations have provided scientific rationale to use CTs as an alternative therapy for various oxidative and inflammatory associated diseases.©2016 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Mazni Abu Zarin Ho Yin Wan Azizul Isha Nurdin Armania | 2016 | Food Science and Human Wellness2016，5，2： | 9 |
| 2 | Dillenia suffruticosa exhibited antioxidant and cytotoxic activity through induction of apoptosis and G 2 /M cell cycle arrest显示文摘 | Nurdin Armania Latifah Saiful Yazan Siti Noorhidayah Musa Intan Safinar Ismail Jhi Biau Foo Kim Wei Chan Husain Noreen Abdul Hamid Hisyam Said Zulfahmi Maznah Ismail | 2013 | Journal of Ethnopharmacology2013，，2： | 2 |
| 3 | maintenance of primary murine hepatocyte functions in multicomponent polymer capsules-in vitro cryopreservation studies显示文摘 | Canaple L Nurdin N | 2001 | J Hepatol2001，34，： | 1 |
| 4 | Physical and Biological Affects of A Surface Coating Procedure on Polyurethane Catheters显示文摘 | P Francois P Vandaux N Nurdin | 1996 | Biomaterials1996，17，7： | 1 |
| 5 | Development of a coculture model of encapsulated cells显示文摘 | Canaple L Nurdin N Angelova N | 2001 | Ann N Y Acad Sci2001，944，： | 1 |
| 6 | Surface properties of a specifically modified high-grade medical polyurethane显示文摘 | Nurdin N Chabrecek P | 2001 | Surface Science2001，91，3： | 1 |
| 7 | Bioeidal polymars active by contact Ⅲ:Ageing of biocidal polyurethane coatings in water显示文摘 | NURDIN N HELARY G SAUVET G | 1993 | Journal of Application Polymer Science1993，50，： | 1 |
| 8 | Osteotome sinusfloor elevation technique without grafting material and immediateimplant placement in atrophic posterior maxilla : report of 2 cases显示文摘 | Nedir R Nurdin IV Simukler-Monclers | 2009 | J Oral Maxillofac Surg2009，67，5： | 1 |
| 9 | Placement of tapered implants using an osteotome sinus floor elevation tech- nique without bone grafting- 1- year results 显示文摘 | Nedir R Nurdin N Szmukler-Moncler S | | Int J Oral Maxilofac Implants0，，4： | 1 |
| 10 | Osteotome sinus floor elevation technique without grafting:a 5-year prospective study显示文摘 | Nedir R Nurdin N Vazquez L | 2010 | Journal of clinical periodontology2010，37，11： | 1 |
| 11 | 显示文摘 | Nurdin N Weilandt E Textor M | 1996 | Journal of Applied Polyrner Science1996，61，： | 1 |
| 12 | Osleotome sinus floor elevation technique without gr'aftiug: a 5-year prospective study显示文摘 | Nedir R Nurdin N Vazquez L el al | 2010 | J Clin Pe- riodontol2010，37，11： | 1 |
| 13 | Placement of taperedimplants using an osteotome sinus floor elevation techniquewithout bone grafting:1-year results显示文摘 | Nedir R Nurdin N Szmukler-Moncler S | 2009 | Int J Oral MaxillofacImplants2009，24，4： | 1 |
| 14 | New phenantrene alkaloids from Cryptocarya crassinervia显示文摘 | KHALIJAH A HAMID H A NURDIN S | 2008 | Fitoterapia2008，79，4： | 1 |
| 15 | Physical and biological effects of a surface coating procedure on polyurethane catheters 显示文摘 | Francois P Vaudaux P Nurdin N | 1996 | Biomaterials1996，17，7： | 1 |
| 16 | Physical and biological effects of a surface coating procedure on polyurethane catheters 显示文摘 | Francois P Vaudaux P Nurdin N | 1996 | Biomaterials1996，17，7： | 1 |
| 17 | Biodiesel Production from Rubber Seed Oil using Activated Cement Clinker as Catalyst显示文摘 | Jolius Gimbun Shahid Ali Chitra Charan Suri Charan Kanwal Liyana Amer Shah Nurul Hidayah Muhamad @ Ghazali Chin Kui Cheng Said Nurdin | 2013 | Procedia Engineering2013，，： | 1 |
| 18 | Osteotome sinus floor elevation technique without grafting: a 5-year prospective study显示文摘 | Nedir R Nurdin N Vazquez L | 2010 | J Clin Periodontol2010，37，11： | 1 |
| 19 | Osteotome sinus floor elevation technique without grafting: a 5-year prospective study 显示文摘 | Nedir R Nurdin N Vazquez L | 2010 | J Clin Periodontol2010，37，11： | 1 |
| 20 | Maintenance of primary routine hepatocyte functions in multicomponent polymer capsules in vitro cryopreservation studies显示文摘 | Canaple L Nurdin N Angelova N | 2001 | J hepatol2001，34，： | 1 |
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