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| 1 | Differential Fault Attack on Camellia显示文摘 | ZHOU Yongbin WU Wenling XU Nannan FENG Dengguo | 2009 | Chinese Journal of Electronics2009，18，1： | 15 |
| 2 | Promoter methylation of Wnt/β-Catenin signal inhibitor TMEM88 is associated with unfavorable prognosis of nonsmall cell lung cancer显示文摘Objective:Recent research has indicated that altered promoter methylation of oncogenes and tumor suppressor genes is an important mechanism in lung cancer development and progression.In this study,we investigated the association between promoter methylation of TMEM88,a possible inhibitor of the Wnt/β-Catenin signaling,and the survival of patients with nonsmall cell lung cancer(NSCLC).Methods:Twelve pairs of tumor and adjacent non-tumor samples were used for microarray analyses of DNA methylation and gene expression.For validation,more than two hundred additional samples were analyzed for methylation using bisulfite pyrosequencing and for gene expression using q RT-PCR.Then the cell function were tested by wound healing,transwell,CCK8 and cell cycle assay.Results:Our analysis of patient specimens showed that TMEM88 methylation was higher in NSCLC tumors(82.2%±10.3,P<0.01)compared with the adjacent normal tissues(65.9%±7.2).The survival analysis revealed that patients with high TMEM88methylation had a shorter overall survival(46 months)compared with patients with low TMEM88 methylation(>56 months;P=0.021).In addition,we found that demethylation treatment could inhibit tumor cell proliferation,migration,and invasion,which was supportive of an association between methylation and survival.Conclusions:Based on these consistent observations,we concluded that TMEM88 may play an important role in NSCLC progression and that promoter methylation of TMEM88 may serve as a biomarker for NSCLC prognosis and treatment. | Rongna Ma Nannan Feng Xiao Yu Hongyan Lin Xiaohong Zhang Oumin Shi Huan Zhang Shuo Zhang Lei Li Min Zheng Ming Gao Herbert Yu Biyun Qian | 2017 | Cancer Biology & Medicine2017，14，4： | 6 |
| 3 | Knockdown of long non-coding RNA LCPAT1 inhibits autophagy in lung cancer显示文摘Objective: Long non-coding RNAs(lnc RNAs) are involved in numerous biological processes in lung cancer cells. In our previous studies, we identified a lnc RNA, ENST00000439577, which is highly expressed in lung carcinomas, and termed it lung cancer progression-associated transcript 1(LCPAT1). To characterize the role of LCPAT1 in lung cancer, we conducted the current study.Methods: Expression of LCPAT1 and autophagy-associated markers in tumor tissues and lung cancer cell lines was determined by real-time quantitative polymerase chain reaction(q PCR). Hematoxylin and eosin(HE) staining, q PCR, Western blot, and immunohistochemistry were performed to evaluate xenografted tumor tissues. Autophagy induced by rapamycin was detected by Western blot and immunofluorescence in lung cancer cell lines.Results: Expression of LCPAT1 and microtubule-associated protein 1 light chain 3 beta(LC3B) was positively correlated in lung cancer. Knockdown of LCPAT1 inhibited tumor growth and suppressed cell autophagy in vivo. Moreover, LCPAT1 knockdown in lung cancer cell lines resulted in decreased autophagy-associated gene expression and alleviated the cell autophagy induced by rapamycin.Conclusions: We speculate that LCPAT1 plays a crucial role in regulating autophagy in lung cancer. | Xiao Yu Xiaofei Ye Hongyan Lin Nannan Feng Sumeng Gao Xiaohong Zhang Yu Wang Herbert Yu Xiaobei Deng Biyun Qian | 2018 | Cancer Biology & Medicine2018，15，3： | 5 |
| 4 | Mechanism of Gravity Effect on Solidification Microstructure of Eutectic Alloy显示文摘The influence of gravity on the solidification microstructure of Al-AI_3Ni eutectic alloy was investigated by using a 50-m-long drop tube.It was found that at different growth rates the average inter-rod spacing was always larger under microgravity(μg)than those under normal gravity(1g).Moreover,with increasing growth rate,the spacing difference between 1 g samples andμg samples reduced progressively.Based on the experimental results and analysis,a physical model was proposed to describe the effect of gravity on the solidification process of eutectic alloy. | Nannan Zhang Xinghong Luo Shaobo Feng Yuhu Ren | 2014 | Journal of Materials Science & Technology2014，30，5： | 3 |
| 5 | Image features extraction and fusion based on joint sparse representation显示文摘 | Nannan Yu Tianshuang Qiu Feng Bi Aiqi Wang | | 0，，05： | 1 |
| 6 | The effect of COD/N ratio on process performance and membrane fouling in a submerged bioreactor显示文摘 | Suping Feng Nannan Zhang Hanchao Liu Xiaolin Du Yongli Liu Hai Lin | 2011 | Desalination2011，，： | 1 |
| 7 | Image features extraction and fusion based on joint sparse representation显示文摘 | YU Nannan QIU Yianshuang BI Feng | 2011 | IEEE Journal of Selected Topics in Signal Processing(S1932-4553)2011，5，5： | 1 |
| 8 | Inverse uncertainty characteristics of pollution source identification for river chemical spill incidents by stochastic analysis显示文摘Identifying source information after river chemical spill occurrences is critical for emergency responses.However,the inverse uncertainty characteristics of this kind of pollution source inversion problem have not yet been clearly elucidated.To fill this gap,stochastic analysis approaches,including a regional sensitivity analysis method,identifiability plot and perturbation methods,were employed to conduct an empirical investigation on generic inverse uncertainty characteristics under a well-accepted uncertainty analysis framework.Case studies based on field tracer experiments and synthetic numerical tracer experiments revealed several new rules.For example,the release load can be most easily inverted,and the source location is responsible for the largest uncertainty among the source parameters.The diffusion and convection processes are more sensitive than the dilution and pollutant attenuation processes to the optimization of objective functions in terms of structural uncertainty.The differences among the different objective functions are smaller for instantaneous release than for continuous release cases.Small monitoring errors affect the inversion results only slightly,which can be ignored in practice.Interestingly,the estimated values of the release location and time negatively deviate from the real values,and the extent is positively correlated with the relative size of the mixing zone to the objective river reach.These new findings improve decision making in emergency responses to sudden water pollution and guide the monitoring network design. | Jiping Jiang Feng Han Yi Zheng Nannan Wang Yixing Yuan | 2018 | Frontiers of Environmental Science & Engineering2018，12，5： | 1 |
| 9 | Image features extraction and fusion basedon joint sparse representation显示文摘 | Yu Nannan Qiu Tianshuang Bi Feng | 2011 | IEEE Journal of Selected Topics in Signal Processing2011，5，5： | 1 |
| 10 | Visuals to Text:A Comprehensive Review on Automatic Image Captioning显示文摘Image captioning refers to automatic generation of descriptive texts according to the visual content of images.It is a technique integrating multiple disciplines including the computer vision(CV),natural language processing(NLP)and artificial intelligence.In recent years,substantial research efforts have been devoted to generate image caption with impressive progress.To summarize the recent advances in image captioning,we present a comprehensive review on image captioning,covering both traditional methods and recent deep learning-based techniques.Specifically,we first briefly review the early traditional works based on the retrieval and template.Then deep learning-based image captioning researches are focused,which is categorized into the encoder-decoder framework,attention mechanism and training strategies on the basis of model structures and training manners for a detailed introduction.After that,we summarize the publicly available datasets,evaluation metrics and those proposed for specific requirements,and then compare the state of the art methods on the MS COCO dataset.Finally,we provide some discussions on open challenges and future research directions. | Yue Ming Nannan Hu Chunxiao Fan Fan Feng Jiangwan Zhou Hui Yu | 2022 | IEEE/CAA Journal of Automatica Sinica2022，9，8： | 1 |
| 11 | Image features extraction and fusion based on joint sparse representation 显示文摘 | Yu Nannan Qiu Tianshuang Bi Feng | 2011 | IEEE Journal of Selected Topics in Signal Processing2011，5，5： | 1 |
| 12 | Comamina- tion assessment of copper, lead, zinc and chromium in dust fall of Jinan, NE China 显示文摘 | FENG Suping LIU Hanchan ZHANG Nannan | 2012 | Environmental Earth Sciences2012，66，： | 1 |
| 13 | ImageFeatures Extraction and Fusion Based on Joint SparseRepresentation显示文摘 | YU Nannan QIU Tianshuang BI Feng | 2011 | IEEE Journal of Selected Topics inSignal Processing2011，5，5： | 1 |
| 14 | Charge storage coating based triboelectric nanogenerator and its applications in self-powered anticorrosion and antifouling显示文摘As a novel energy-harvesting device,a triboelectric nanogenerator(TENG)can harvest almost all mechanical energy and transform it into electrical energy,but its output is low.Although the micro-nano structures of triboelectrode surfaces can improve their output efficiency,they lead to high costs and are not suitable for large-scale applications.To address this problem,we developed a novel TENG coating with charge-storage properties.In this study,we modified an acrylic resin,a friction material,with nano-BaTiO_(3) particles and gas phase fluorination.The charge-trapping ability of nanoparticles was used to improve the output of TENG.The short-circuit current and the output voltage of coating-based TENGs featuring charge storage and electrification reached 15μA and 800 V,respectively,without decay for longtime working.On this basis,self-powered anticorrosion and antifouling systems are designed to reduce the open circuit potential of A3 steel by 510 mV and reduce the adhesion rate of algae on the surface of metal materials.This study presents a high-output,stable,coating-based TENG with potential in practical applications for anticorrosion and antifouling. | Zhitao Zhang Yupeng Liu Min Feng Nannan Wang Changhe Du Shu Peng Yufei Guo Yongjian Liu Ying Liu Daoai Wang | 2023 | Frontiers of Materials Science2023，17，1： | 0 |
| 15 | New starch capsules with antistatic,anti-wear and superlubricity properties显示文摘Adsorption of drug powder is caused by triboelectrification on the surface of starch capsule during filling process.Furthermore,high wear rate and poor water lubricity also hinder the further practical applications of traditional starch capsule.To solve these problems,a glycerol-modified starch capsule with perfect anti-triboelec-trification and enhanced lubrication performance was fabricated.Hydrogen bond between glycerol and starch molecules could reduce the bound water content on the capsule surface and thus realizes anti-triboelectrification.By adding glycerol,a three-tier structure composed of starch-glycerol-water is formed through hydrogen bonding on the surface of the starch film,which has been proven to be favorable for lubrication performance.When 5% glycerol is added,the short-circuit current(I_(sc))of starch-based triboelectric nanogenerator(TENG)is reduced by 86%,and the wear volume of the starch film is reduced by 89%.Underwater lubrication condition,the lubrication performance of the starch-glycerol film can reach the super lubricated level with a friction coefficient of about 0.005.This work provides a new route to obtain modified starch capsules with improved anti-triboelectrification property,reduced wear rate and superlubricity property. | Nannan WANG Youbin ZHENG Yange FENG Liqiang ZHANG Min FENG Xiaojuan LI Daoai WANG | 2021 | Frontiers of Materials Science2021，15，2： | 0 |
| 16 | Abrin P2 suppresses proliferation and induces apoptosis of colon cancer cells via mitochondrial membrane depolarization and caspase activation显示文摘在人的结肠癌 HCT-8 房间上探索 abrin P2 的细胞毒素的机制, abrin P2 从 Abrus precatorius L 的种子被孤立。abrin P2 向 12 根不同人的癌症房间线展出了 cytotoxicity,这被发现。我们的结果证明 abrin P2 压制了人的结肠癌房间(HCT-8 房间) 的增长并且在 S 和 G2/M 阶段导致了房间周期拘捕。abrin P2 由禁止了房间增长的机制经由 cyclin B1 的下面规定,增殖房间原子抗原和 Ki67,以及 P21 的起来规定。另外, abrin P2 处于 HCT-8 房间 apoptosis 的率导致了剂量依赖者和时间依赖者增加。有 Z-VAD-FMK,一个用途广泛的 caspase 禁止者,和 abrin P2 的治疗证明 abrin P2 经由 caspases 的激活导致了 HCT-8 房间 apoptosis。一起,我们的结果揭示了那 abrin 在 HCT-8 房间的导致 P2 的 apoptosis 与 caspases-3/-8/-9,在 Bcl-2/Bax 比率的减小, mitochondrial 膜潜力的损失,和细胞色素 c 的增加的激活被联系版本。我们进一步证明 abrin P2 管理有效地在裸体老鼠压制了结肠癌异种皮移植的生长。这是 abrin P2 有效地由压制增长并且导致 apoptosis 在 vivo 并且在 vitro 禁止结肠癌细胞生长的第一份报告。 | Ying Yu Runmei Yang Xiuyun Zhao Dandan Qin Zhaoyang Liu Fang Liu Xin Song Liqin Li Renqing Feng Nannan Gao | 2016 | Acta Biochimica et Biophysica Sinica2016，48，5： | 0 |
| 17 | On-chip sorting of orbital angular momentum beams using Bloch surface wave structures显示文摘Owing to their unique optical properties and new degrees of freedom,orbital angular momentum(OAM)beams have been applied in various fields.Detection of the topological charges(TCs)of OAM beams is the key step for their applications.However,on-chip sorting of OAM beams with large TCs still remains a challenge.In this paper,Bloch surface wave(BSW)structures with five semi-ring shaped nanoslits are modeled.A spatial separation of 135 nm on the chip is obtained between two neighboring OAM states.OAM beams with TCs up to 35 can be successfully sorted by the BSW structures,which is much larger than that using metallic structures(only seven).BSW structures exhibit better OAM sorting performances than metallic structures.We systematically show how the lower attenuation of BSW structures leads to far superior separation ability compared to surface plasmons propagating on metallic structures.In addition,sorting of two OAM beams with different TCs simultaneously can be achieved in this way.Our results reveal that BSW structures should be an excellent solution for OAM sorting with large TCs,which is beneficial for applications in integrated on-chip devices and optical communications. | NANNAN LI QI ZOU YIZHI LAN YAQI WANG JUN ZHANG MICHAEL SOMEKH CHANGJUN MIN FU FENG XIAOCONG YUAN | 2023 | Photonics Research2023，11，11： | 0 |
| 18 | Removal of Cu(ll) ions from aqueous solution by activated carbon impregnated with humic acid显示文摘 | Hanchao LIU Suping FENG Nannan ZHANG Xiaolin DU Yongli LIU | 2014 | Frontiers of Environmental Science & Engineering2014，8，3： | 0 |
| 19 | Boosting image-guiding radiation therapy through W_(18)O_(49) nanospheres and the second near-infrared light irradiation显示文摘More than 60%of cancer patients receive radiation therapy(RT)during their anticancer treatment.However,there is a huge challenge to improve the therapeutic efficacy of RT in less radioresponsive tumors and decrease damages dealt to the surrounding healthy tissues.Herein,we have reported the development of an efficacious RT treatment of relatively radio-resistant breast cancer using W_(18)O_(49)nanospheres and the second near-infrared(NIR)light irradiation.Featuring the X-ray attenuation ability and photothermal effect,together with ability to generate intracellular singlet oxygen and·OH,W_(18)O_(49)nanospheres can significantly increase radiation-induced DNA damage and decrease the mitochondrial membrane potential of cancer cells during RT,causing in nearby three-times improvement in inhibiting the proliferation of 4T1 cells.The in vivo evaluations verify that a rather effective therapeutic outcome is achieved by treatment of 4T1 tumor xenograft with NIR-enhanced RT using W_(18)O_(49)nanospheres.Moreover,the X-ray attenuation ability and the strong near-infrared absorption of W_(18)O_(49)nanospheres have enabled highly resolved in vivo computer tomography(CT)/photoacoustic(PA)imaging.This work presents an“all-in-one”synergistic platform to improve the therapeutic efficacy of RT in less radioresponsive tumors,therefore opening a new door for multimodal cancer therapy. | Nannan Zheng Shouhao Zhang Lu Wang Zhilin Qi Qiang Peng Lingrui Jian Yang Bai Yue Feng Jiachen Shen Ranxu Wang Jia Jiao Wanhai Xu Shaoqin Liu | 2022 | Nano Research2022，15，3： | 0 |
| 20 | Molecular Detection of Sugarcane Ratoon Stunting Disease in Hainan Sugarcane-growing Areas显示文摘[Objective]The paper was to clarify the occurrence of sugarcane ratoon stunting disease(RSD)in Hainan sugarcane-growing areas.[Method]In 2019,270 samples of sugarcane leaves were collected from six main sugarcane-growing areas in Hainan Province,and RSD was detected by PCR assay with specific primers.[Result]RSD was detected out in 41 out of 270 sugarcane samples,with an average detection rate of15.19%.The detection rates of RSD were different in six sugarcane-growing areas;the detection rate of RSD in Danzhou sugarcane-growing area was the highest of 22.00%;the detection rate of RSD in Lingao sugarcane-growing area was the lowest of 9.26%.RSD was detected out in 8 out of10 main sugarcane cultivars,among which Xintaitang 22 suffered the heaviest damage,with the positive detection rate of 45.83%;RSD had not been detected out in Zhongtang 1 and Zhongtang 2,while the positive detection rates of RSD in the remaining seven sugarcane cultivars were10.00%-31.25%.[Conclusion]RSD commonly occurs in Hainan sugarcane-growing areas.The research results provide a basis for scientific prevention and control of RSD and promotion and application of healthy virus-free sugarcane seedlings. | Shen Linbo Xiong Guoru Feng Xiaoyan Wang Wenzhi Feng Cuilian Zhao Tingting Wang Jungang Wu Nannan Zhang Shuzhen | 2020 | Plant Diseases and Pests2020，11，1： | 0 |
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