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| 1 | 中国首例冻存卵巢组织移植报告显示文摘随着癌症医学的发展,细胞毒性抗癌药物与放射治疗在临床上的普遍应用使癌症患者的生存率大幅提高,如49岁以下乳腺癌患者5年生存率约90%。超过70%的年轻癌症患者有生育要求,但性腺毒性治疗会对卵巢功能造成严重的不可逆性损伤。例如,乳腺癌患者经FEC或FAC方案化学药物治疗(以下简称化疗)后,闭经的发生率高达50%-65%。 | 阮祥燕 杜娟 卢丹 孔为民 代荫梅 阴赪宏 严松彪 金凤羽 金婧 崔亚美 费秀珍 Matthias Korell Jana Liebenthron Markus Montag Alfred O.Mueck | 2016 | 首都医科大学学报2016，37，6： | 33 |
| 2 | 基于49例软组织上皮样血管内皮瘤研究的风险分类建议显示文摘 | Deyrup A T Tighiouart M Montag A G 饶秋(摘译) | 2008 | 临床与实验病理学杂志2008，24，4： | 30 |
| 3 | 中国冻存卵巢组织自体移植后首例活产报道显示文摘全球每年新增女性恶性肿瘤患者约920万例[1],抗癌治疗的性腺毒性可导致卵巢功能严重受损[2-3],因此开展生育力保护技术尤为重要。卵巢组织冻存是青春期前女童与疾病治疗无法延迟的患者惟一的生育力保护方法[4],自2004年全球首例活产报道至今[5],累计出生的婴儿数已超过200例[6],其有效性与安全性得到广泛的验证,成为一项临床常规技术[7]。首都医科大学附属北京妇产医院阮祥燕团队建立了首个卵巢组织冻存库[8],并于2016年完成了中国首例卵巢组织冻存移植[9],至今已成功移植10例,术后患者卵巢功能均得以恢复[10]。2021年,阮祥燕团队报道了中国首例自体卵巢组织冻存移植后自然妊娠病例[11-12],该患者现已顺利分娩,报道如下。 | 阮祥燕 杜娟 卢丹 段微 金凤羽 孔为民 吴玉梅 代荫梅 严松彪 阴赪宏 李扬璐 程姣姣 贾婵维 刘晓巍 吴青青 谷牧青 鞠蕊 许新 杨瑜 金婧 Matthias Korell Markus Montag Jana Liebenthron Alfred OMueck | 2021 | 中国临床医生杂志2021，49，10： | 20 |
| 4 | Immediate nipple-areola-sparing mastectomy reconstruction: An update on oncological and reconstruction techniques显示文摘Nipple-sparing mastectomy(NSM) is a safe technique in patients who are candidates for conservation breast surgery. However, there is worry concerning its oncological safety and surgical outcome in terms of postoperative complications. The authors reviewed the literature to evaluate the oncological safety, patient selection, surgical techniques, and also to identify the factors influencing postoperative outcome and complication rates. Patient selection and safety related to NSM are based on oncological and anatomical parameters. Among the main criteria, the oncological aspects include the clinical stage of breast cancer, tumor characteristics and location including small, peripherally located tumors, without multicentricity, or for prophylactic mastectomy. Surgical success depends on coordinated planning with the oncological surgeon andcareful preoperative and intraoperative management. In general, the NSM reconstruction is related to autologous and alloplastic techniques and sometimes include contra-lateral breast surgery. Choice of reconstructive technique following NSM requires accurate consideration of various patient related factors, including: breast volume, degree of ptosis, areola size, clinical factors, and surgeon's experience. In addition, tumor related factors include dimension, location and proximity to the nipple-areola complex. Regardless of the fact that there is no unanimity concerning the appropriate technique, the criteria are determined by the surgeon's experience and the anatomical aspects of the breast. The positive aspects of the technique utilized should include low interference with the oncological treatment, reproducibility, and long-term results. Selected patients can have safe outcomes and therefore this may be a feasible option for early breast cancer management. However, available data demonstrates that NSM can be safely performed for breast cancer treatment in selected cases. Additional studies and longer follow-up are necessary to define consistent selection criteria for NSM. | Alexandre Mendon?a Munhoz Eduardo Montag José Roberto Filassi Rolf Gemperli | 2014 | World Journal of Clinical Oncology2014，5，3： | 15 |
| 5 | 冻存卵巢组织移植成功--首次报道显示文摘目的通过卵巢组织冻存技术及自体移植手术保护癌症患者生育力与内分泌功能。方法对1例40岁宫颈鳞癌IIb期患者在放化疗前进行卵巢组织取材、冻存,待其癌症痊愈后进行冻存卵巢组织自体移植手术,随访监测患者的激素水平、卵泡发育情况、月经恢复情况以及绝经相关症状。结果卵巢组织移植4个月后,改良Kupperman评分由20分降低至<5分,绝经相关症状基本消失,卵泡刺激素(FSH)降低至22.79 IU/L,此后继续下降至6 IU/L,雌二醇(E_2)由<11.8 ng/L升高至84.46 ng/L,B超监测到有卵泡发育且月经恢复。结论卵巢组织冻存移植4个月后卵巢功能恢复正常,证明卵巢组织在临床上移植成功。 | 阮祥燕 杜娟 李扬璐 金凤羽 孔为民 卢丹 吴玉梅 代荫梅 周琦 赵群 阴赪宏 严松彪 Matthias Korell Jana Liebenthron Markus Montag 王虎生 程姣姣 李雪 谷牧青 Alfred O.Mueck | 2018 | 中华生殖与避孕杂志2018，38，9： | 12 |
| 6 | 中国自体卵巢组织冻存移植后成功妊娠首例报道显示文摘女性生育力保护技术的需求急剧增长。全球每年新增恶性肿瘤患者超过1400万例[1],抗癌治疗在显著降低患者死亡率的同时,其性腺毒性却对患者的卵巢功能造成严重损伤,尤其在造血干细胞移植后,卵巢早衰的发生率可达100%[2]。随着发病年龄的年轻化与生育年龄的推迟,78.3%的年轻恶性肿瘤患者有强烈的生育需求[3]。因此,生育力保护成为全球关注的热点。卵巢组织冻存是抗癌治疗无法延迟的女性及青春期前女童唯一的生育力保护选择[4],且有卵泡储备量大、无需促排卵、不受月经周期影响、不仅保护生育力还可保存卵巢内分泌功能等诸多优势[5]。 | 阮祥燕 杜娟 卢丹 段微 金凤羽 孔为民 吴玉梅 代荫梅 严松彪 阴赪宏 李扬璐 程姣姣 贾婵维 刘晓巍 吴青青 谷牧青 鞠蕊 许新 杨瑜 金婧 Matthias Korell Markus Montag JanaLiebenthron Alfred OMueck | 2021 | 中国临床医生杂志2021，49，3： | 7 |
| 7 | Current aspects of therapeutic reduction mammaplasty for immediate early breast cancer management: An update显示文摘Breast-conservation surgery(BCS) is established as a safe surgical treatment for most patients with early breast cancer. Recently, advances in oncoplastic techniques are capable of preserving the breast form and quality of life. Although most BCS defects can be managed with primary closure, the aesthetic outcome may be unpredictable. Among technical options, therapeutic reduction mammaplasty(TRM) remains a useful procedure since the BCS defect can be repaired and the preoperative appearance can be improved, resulting in more proportional breasts. As a consequence of rich breast tissue vascularization, the greater part of reduction techniques have based their planning on preserving the pedicle of the nipple-areola complex after tumor removal. Reliable circulation and improvement of a conical shape to the breast are commonly described in TRM reconstructions. With an immediate approach, the surgical process is smooth since both procedures can be carried out in one operative setting. Additionally,it permits wider excision of the tumor, with a superior mean volume of the specimen and potentially reduces the incidence of margin involvement. Regardless of the fact that there is no consensus concerning the best TRM technique, the criteria is determined by the surgeon's experience, the extent/location of glandular tissue resection and the size of the defect in relation to the size of the remaining breast. The main advantages of the technique utilized should include reproducibility, low interference with the oncological treatment and long-term results. The success of the procedure depends on patient selection, coordinated planning and careful intra-operative management. | Alexandre Mendona Munhoz Eduardo Montag Rolf Gemperli | 2014 | World Journal of Clinical Oncology2014，5，1： | 5 |
| 8 | 软组织上皮样血管内皮瘤的危险度分级显示文摘 | Deyrup A T Tighiouart M Montag A G 潘敏鸿(摘译) 周晓军(审校) | 2008 | 临床与实验病理学杂志2008，24，5： | 5 |
| 9 | Acetylcholinesterase inhibitor modifications: a promising strategy to delay the progression of Alzheimer's disease显示文摘Alzheimer’s disease(AD),a fatal,progressive,neurodegenerative disorder,is the most common cause of old-age dementia,accounting for 50–75%of dementia patients.Early stages of AD are marked by vocabulary shrinkage,spatial disorientation,depression,apraxia,and deterioration of recent forms of declarative memory.In course of time,the | Soumee Bhattacharya Dirk Montag | 2015 | Neural Regeneration Research2015，10，1： | 4 |
| 10 | Sarcoma botryoid of the cer-vix:excision followed by adjuvant chemotherapy for preservation of reproductive function显示文摘 | Gordon AN Montag TW | 1990 | Gynecol Oncol1990，36，： | 1 |
| 11 | Differential expression of mu- cin genes in mammary and extramammary Paget's disease显示文摘 | Kuan SF Montag AG Hart J | 2001 | Am J Surg Pathol2001，25，12： | 1 |
| 12 | New natural draft cooling tower of 200m of height 显示文摘 | Busch D Harte R Krtzig Montag W B U | 2002 | Engineering Structures2002，24，12： | 1 |
| 13 | Reversal of immunoparalysis by recombinant human granulocyte - macrophage colony - stimulating factor in patients with severe sepsis显示文摘 | Nierhaus A Montag B Timmler N | 2003 | Intensive Care Med2003，29，4： | 1 |
| 14 | Sarcoma botryoid of the cervix: excision followed by adjuvant chemotherapy for preservation of reproductive function显示文摘 | Gordon AN Montag TW | 1990 | Gynecol Oncol1990，36，1： | 1 |
| 15 | Melting Temperature of High-Temperature Fixed Points for Thermocouple Calibrations显示文摘 | Pearce J V Montag V Lowe D | 2011 | International Journal of Thermophysics2011，32，1： | 1 |
| 16 | Insulin-degrading enzyme is differentially expressed and denelopmentally regulated in various rat tissues显示文摘 | Wen liang KUO Anthony G Montag | 1993 | Endocrinology1993，2，： | 1 |
| 17 | Embryonal rhabdomyosarcoma of the uterine corpus and cervix显示文摘 | Montag TW D'Ablaing G Schlaerth JB | 1986 | Gynecol Oncol1986，25，： | 1 |
| 18 | Long - term survival of xe-nogeneic pancreatic islet grafts induced by CTLA41g 显示文摘 | Lenschow D J Zeng Y Montag A | 1992 | Science1992，257，5071： | 1 |
| 19 | Outcome analysis of breast-conservation surgery and immediate latissimus dorsiflap reconstruction in patients with T1 to T2 breast cancer显示文摘 | Munhoz AM Montag E Fels KW | 2005 | Plast Reconstr Surg2005，116，： | 1 |
| 20 | Deferred, self-organizing BSP trees 显示文摘 | Ar S Montag G Tal A | 2002 | Computer Graphics Forum2002，21，3： | 1 |
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