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| 1 | In vitro antioxidant,cytotoxic,thrombolytic activities and phytochemical evaluation of methanol extract of the A.philippense L.leaves显示文摘Objective:To study the leaves of Adiantum philippense L.for their antioxidant,cytotoxicity and thrombolytic activities and to perform phytochemical evaluation.Methods:In-vitro antioxidant activity of extract was studied using DPPH radical scavenging,reducing power,total phenol and total flavonoid content determination assays.The cytotoxic activity was determined using brine shrimp lethality bioassay,thrombolytic activity by clot disruption and phytochemical potential by qualitative analysis.Results:The antioxidant activity of the extracts was found promising.The reducing power of this crude extract increase with the increase of concentration;IC_(50)values of DPPH scavenging activity was(140.00±0.86)μg/mL as compared to ascorbic acid[IC_(50)(130.00±0.76)μg/mL];Total phenol and total flavonoids content were(148.26±0.24)mg/mL and(163.06±0.56)mg/mL respecnvely.In cytotoxicity assay the LC_(50)values of the sample was(106.41±0.78)μg/mL where as for standard vincristin sulphate was(08.50±0.24)μg/mL as a positive control and the extract shows(12.8611.02)%clot lytic whereas standard streptokinase shows(30.86+0.44%clot lytic activity in thrombolytic assay.The phytochemical evaluation indicates the presence of chemical constituents including carbohydrates,alkaloids,saponins,glycosides,flavonoids.Conclusions:This study shows that the methanol extract of leaves of Adiantum philippense L.has bioactivitv but further compound isolation is necessary to confirm the activities of individual compounds. | Mohammad Sekendar Ali Mohammad Ruhul Amin Chowdhury Mohammad Imtiaz Kamal Mohammad Aslam Hossain | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，6： | 3 |
| 2 | Recent Insights into Signaling Responses to Cope Drought Stress in Rice显示文摘Drought is one of the hot topics needing urgent attention in the current era of climate change.It massively disturbs the rice growth and productivity and is becoming a serious threat.The drought avoidance strategies in rice include stomatal closure,cellular adaptation and changes in root development.Moreover,the endogenous plant hormones(abscisic acid and jasmonic acid)and reactive oxygen species have paramount importance in drought tolerance in rice.The drought tolerance induces modification in biochemical,molecular and physiological properties of plants.At the molecular level,expression of several transcription-factors is modulated which further determine the activation of drought responsive gene families.Mitogen activated protein kinases and Ca signaling pathways initiate an array of signaling cascade for mediating the gene expression in rice.Approaches,conventional breeding methods combined with modern emerging techniques such as genetic engineering,to improve rice drought tolerance were discussed.This review provided recent insights into major regulatory factors against drought stress,signaling mechanisms and molecular engineering strategies(including conventional transgenic and recent genome editing approaches)to induce drought tolerance in rice. | Muhammad Mahran ASLAM Muhammad Abdul Rehman RASHID Mohammad Aquil SIDDIQUI Muhammad Tahir KHAN Fozia FARHAT Shafquat YASMEEN Imtiaz Ahmad KHAN Shameem RAJA Fatima RASOOL Mahboob Ali SIAL ZHAO Yan | 2022 | Rice science2022，29，2： | 2 |
| 3 | Bacterial translocation across ePTFE vascular graft surfaces显示文摘 | Supriya Narasimhan Saima Aslam Peter H. Lin Carlos F. Bechara Mohammad D. Mansouri Rabih O. Darouiche | 2010 | Journal of Infection2010，，6： | 1 |
| 4 | Common Origin for Electron and Hole Traps in MOS Device显示文摘 | | 1987 | IEEE Trans on Electron Devices1987，34，12： | 1 |
| 5 | Effect of fasting on protein metabolism in muscle tissue of Larimichthys crocea revealed by transcriptome and proteome显示文摘The large yellow croaker(Larimichthys crocea)is an important mariculture fish in China.Farmed large yellow croaker undergo periods of fasting to adapt to the environment or to improve meat quality.To better understand the physiological responses of their muscle tissues to fasting stresses,we analyzed the transcriptomes and proteome s of both normally-fed and fasting fish groups and identified 7578 differentially expressed genes(DEGs)and 297 differentially expressed proteins(DEPs)among them.Gene ontology and KEGG analysis showed that the enriched biological pathways were mainly involved in various synthetic and catabolic pathways,especially the protein metabolism.Based on the omics data,nine DEGs related to muscle composition(CAN3,MYL3,and TNNC2),growth(MSTN and MYF5),autophagy(TSC2 and ULK1),and the ubiquitin proteasome pathway(PRS6 B and UCHL3)were examined using qPCR.In response to fasting stress,MYL3 and TNNC2 were significantly downregulated,while genes associated with autophagy and the ubiquitin proteasome pathway were significantly upregulated.In re sponse to fasting stres s,MYL3,TNNC2,and MYF5 positively correlated with muscle growth were significantly downregulated,while inhibiting growth MSTN and genes associated with autophagy and the ubiquitin proteasome pathways were significantly upregulated.These results clarify the effects of fasting on metabolic changes in their muscle components and growth at the molecular level. | Yu ZHANG Weiliang SHEN Juan LI Baoxiao ZHENG Zhengjia LOU Mohammad Aslam HOSAIN Baoying QIAN Liangyi XUE | 2021 | Journal of Oceanology and Limnology2021，39，5： | 1 |
| 6 | Isolation of a flavonoid from Feronia limonia显示文摘 | Javed Intekhab Mohammad Aslam | 2009 | Journal of Saudi Chemical Society2009，，3： | 1 |
| 7 | Traffic Priority-Aware Medical Data Dissemination Scheme for IoT Based WBASN Healthcare Applications显示文摘Wireless Body Area Sensor Network(WBASN)is an automated system for remote health monitoring of patients.WBASN under umbrella of Internet of Things(IoT)is comprised of small Biomedical Sensor Nodes(BSNs)that can communicate with each other without human involvement.These BSNs can be placed on human body or inside the skin of the patients to regularly monitor their vital signs.The BSNs generate critical data as it is related to patient’s health.The data traffic can be classified as Sensitive Data(SD)and Non-sensitive Data(ND)packets based on the value of vital signs.These data packets have different priority to deliver.The ND packets may tolerate some delay or packet loss whereas,the SD packets required to be delivered on time with minimized packet loss otherwise it can be life threating to the patients.In this research,we propose a Traffic Priority-aware Medical Data Dissemination(TPMD2)scheme forWBASN to deliver the data packets according to their priority based on the sensitivity of the data.The assessment of the proposed scheme is carried out in various experiments.The simulation results of the TPMD2 scheme indicate a significant improvement in packets delivery,transmission delay and energy efficiency in comparison with the existing schemes. | Muhammad Anwar Farhan Masud Rizwan Aslam Butt Sevia Mahdaliza Idrus Mohammad Nazir Ahmad Mohd Yazid Bajuri | 2022 | Computers, Materials & Continua2022，，6： | 1 |
| 8 | Green5G: Enhancing Capacity and Coverage in Device-to-Device Communication显示文摘With the popularity of green computing and the huge usage of networks,there is an acute need for expansion of the 5G network.5G is used where energy efficiency is the highest priority,and it can play a pinnacle role in helping every industry to hit sustainability.While in the 5G network,conventional performance guides,such as network capacity and coverage are still major issues and need improvements.Device to Device communication(D2D)communication technology plays an important role to improve the capacity and coverage of 5G technology using different techniques.The issue of energy utilization in the IoT based system is a significant exploration center.Energy optimizationin D2D communication is an important point.We need to resolve this issue for increasing system performance.Green IoT speaks to the issue of lessening energy utilization of IoT gadgets which accomplishes a supportable climate for IoT systems.In this paper,we improve the capacity and coverage of 5G technology using Multiple Inputs Multiple Outputs(MU-MIMO).MUMIMO increases the capacity of 5G in D2D communication.We also present all the problems faced by 5G technology and proposed architecture to enhance system performance. | Abdul Rehman Javed Rabia Abid Bakhtawar Aslam Hafiza Ammara Khalid Mohammad Zubair Khan Omar H.Alhazmi Muhammad Rizwan | 2021 | Computers, Materials & Continua2021，，5： | 0 |
| 9 | A Rare Form of Major Self-mutilation in a Patient with Delusional Disorder显示文摘Self-mutilation is defined as the intentional,direct injuring of body tissue without suicidal intent.In this article we report the case of a 45-year-old male who presented to the emergency department with a history of incising his abdomen and chopping his intestines into pieces.The patient also brought the chopped pieces along with himself.He was operated on,and a resection and anastomosis was done.Postoperative recovery of the patient was uneventful.After a psychiatric assessment was done,it was found that he was suffering from delusional disorder.Owing to such rare presentation of major self-mutilation in a patient with delusional disorder,this case is being reported here. | Shahbaz Habib Faridi Mohammad Amir Usmani Bushra Siddiqui Mohammad Aslam | 2016 | Journal of Forensic Science and Medicine2016，2，2： | 0 |
| 10 | Pineapple SWEET10 is a glucose transporter显示文摘SWEET transporters are a unique class of sugar transporters that play vital roles in various developmental and physiological processes in plants.While the functions of SWEETs have been well established in model plants such as Arabidopsis,their functions in economically important fruit crops like pineapple have not been well studied.Here we aimed to investigate the substrate specificity of pineapple SWEETs by comparing the protein sequences of known glucose and sucrose transporters in Arabidopsis with those in pineapple.Our genome-wide approach and 3D structure comparison showed that the Arabidopsis SWEET8 homolog in pineapple,AcSWEET10,shares similar sequences and protein properties responsible for glucose transport.To determine the functional conservation of AcSWEET10,we tested its ability to complement glucose transport mutants in yeast and analyzed its expression in stamens and impact on the microspore phenotype and seed set in transgenic Arabidopsis.The results showed that AcSWEET10 is functionally equivalent to AtSWEET8 and plays a critical role in regulating microspore formation through the regulation of the Callose synthase5(CalS5),which highlights the importance of SWEET transporters in pineapple.This information could have important implications for improving fruit crop yield and quality by manipulating SWEET transporter activity. | Beenish Fakher M.Arif Ashraf Lulu Wang Xiaomei Wang Ping Zheng Mohammad Aslam Yuan Qin | 2023 | Horticulture Research2023，10，10： | 0 |
| 11 | Positional signals establishment in the regulation of female germline specification显示文摘The female germline specification process of a single megaspore mother cell(MMC)of ovule primordium(nucellus)is intriguingly complex because it involves the interaction of different pathways tightly linked with positional information.Various Arabidopsis genes,including the stem cell promoting factor WUSCHEL,have already been shown to be involved in this precise regulation process.Recently,there have been some reviews on MMC specialization,mainly from the aspects of epigenetics,microRNAs and gene regulatory networks.However,those reviews have not taken into consideration the function of positional signals in female germline specification.Here,we review major progress in the cell fate control of female germline specification,highlighting the functions of positional cues. | Hanyang Cai Suzhuo Ma Han Su Kaichuang Liu Mohammad Aslam Yuan Qin | 2022 | Seed Biology2022，1，1： | 0 |
| 12 | PIN FORMED 2 Modulates the Transport of Arsenite in Arabidopsis thaliana显示文摘Arsenic contamination is a major environmental issue,as it may lead to serious health hazard.The reduced trivalent formof inorganic arsenic,arsenite,is in generalmore toxic to plants comparedwith the fully oxidized pentavalent arsenate.Theuptakeof arsenite inplants hasbeenshown tobemediatedthrough a large subfamily of plant aquaglyceroporins,nodulin 26-like intrinsic proteins(NIPs).However,the efflux mechanisms,as well as themechanismof arsenite-induced root growth inhibition,remain poorly understood.Usingmolecular physiology,synchrotron imaging,and root transport assay approaches,we show that the cellular transport of trivalent arsenicals inArabidopsis thalianais stronglymodulatedbyPINFORMED2(PIN2)auxin efflux transporter.Root transport assay using radioactive arsenite,X-ray fluorescence imaging(XFI)coupled with X-ray absorption spectroscopy(XAS),and inductively coupled plasma mass spectrometry analysis revealed that pin2 plants accumulate higher concentrations of arsenite in roots comparedwith the wild-type.At the cellular level,arsenite specifically targets intracellular sorting of PIN2 and thereby alters the cellular auxin homeostasis.Consistently,loss of PIN2 function results in arsenite hypersensitivity in roots.XFI coupled with XAS further revealed that loss of PIN2 function results in specific accumulation of arsenical species,but not the other metals such as iron,zinc,or calcium in the root tip.Collectively,these results suggest that PIN2 likely functions as an arsenite efflux transporter for the distribution of arsenical species in planta. | Mohammad Arif Ashraf Kana Umetsu Olena Ponomarenko Michiko Saito Mohammad Aslam Olga Antipova Natalia Dolgova Cheyenne D.Kiani Susan Nehzati Keitaro Tanoi Katsuyuki Minegishi Kotaro Nagatsu Takehiro Kamiya Toru Fujiwara Christian Luschnig Karen Tanino Ingrid Pickering Graham N.George Abidur Rahman | 2020 | Plant Communications2020，1，3： | 0 |
| 13 | Chromosome-scale genome sequence of Suaeda glauca sheds light on salt stress tolerance in halophytes显示文摘Soil salinity is a growing concern for global crop production and the sustainable development of humanity.Therefore,it is crucial to comprehend salt tolerance mechanisms and identify salt-tolerance genes to enhance crop tolerance to salt stress.Suaeda glauca,a halophyte species well adapted to the seawater environment,possesses a unique ability to absorb and retain high salt concentrations within its cells,particularly in its leaves,suggesting the presence of a distinct mechanism for salt tolerance.In this study,we performed de novo sequencing of the S.glauca genome.The genome has a size of 1.02 Gb(consisting of two sets of haplotypes)and contains 54761 annotated genes,including alleles and repeats.Comparative genomic analysis revealed a strong synteny between the genomes of S.glauca and Beta vulgaris.Of the S.glauca genome,70.56%comprises repeat sequences,with retroelements being the most abundant.Leveraging the allele-aware assembly of the S.glauca genome,we investigated genome-wide allele-specific expression in the analyzed samples.The results indicated that the diversity in promoter sequences might contribute to consistent allele-specific expression.Moreover,a systematic analysis of the ABCE gene families shed light on the formation of S.glauca’s flower morphology,suggesting that dysfunction of A-class genes is responsible for the absence of petals in S.glauca.Gene family expansion analysis demonstrated significant enrichment of Gene Ontology(GO)terms associated with DNA repair,chromosome stability,DNA demethylation,cation binding,and red/far-red light signaling pathways in the co-expanded gene families of S.glauca and S.aralocaspica,in comparison with glycophytic species within the chenopodium family.Time-course transcriptome analysis under salt treatments revealed detailed responses of S.glauca to salt tolerance,and the enrichment of the transition-upregulated genes in the leaves associated with DNA repair and chromosome stability,lipid biosynthetic process,and isoprenoid metabolic process.Additionally,genome-wide analysis of transcription factors indicated a significant expansion of FAR1 gene family.However,further investigation is needed to determine the exact role of the FAR1 gene family in salt tolerance in S.glauca. | Yan Cheng Jin Sun Mengwei Jiang Ziqiang Luo Yu Wang Yanhui Liu Weiming Li Bing Hu Chunxing Dong Kangzhuo Ye Zixian Li Fang Deng Lulu Wang Ling Cao Shijiang Cao Chenglang Pan Ping Zheng Sheng Wang Mohammad Aslam Hong Wang Yuan Qin | 2023 | Horticulture Research2023，10，9： | 0 |
| 14 | Characterization of germline development and identification of genes associated with germline specification in pineapple显示文摘Understanding germline specification in plants could be advantageous for agricultural applications.In recent decades,substantial efforts have been made to understand germline speci fication in several plant species,including Arabidopsis,rice,and maize.However,our knowledge of germline speci fication in many agronomically important plant species remains obscure.Here,we characterized the female germline speci fication and subsequent female gametophyte development in pineapple using callose staining,cytological,and whole-mount immunolocalization analyses.We also determined the male germline speci fication and gametophyte developmental timeline and observed male meiotic behavior using chromosome spreading assays.Furthermore,we identi fied 229 genes that are preferentially expressed at the megaspore mother cell(MMC)stage during ovule development and 478 genes that are preferentially expressed at the pollen mother cell(PMC)stage of anther development using comparative transcriptomic analysis.The biological functions,associated regulatory pathways and expression patterns of these genes were also analyzed.Our study provides a convenient cytological reference for exploring pineapple germline development and a molecular basis for the future functional analysis of germline speci fi cation in related plant species. | Lihua Zhao Liping Liu Yanhui Liu Xianying Dou Hanyang Cai Mohammad Aslam Zhimin Hou Xingyue Jin Yi Li Lulu Wang Heming Zhao Xiaomei Wang Adrien Sicard Yuan Qin | 2021 | Horticulture Research2021，8，1： | 0 |
| 15 | Analysis and Design of Flexible Pavements by Empirical Tools显示文摘 | Sanjay Kumar Misra Mohammad Zafar Khan Aslam Amirahmad | 2011 | Journal of Civil Engineering and Architecture2011，5，2： | 0 |
| 16 | pH sensing in plants显示文摘In plants,the alteration in the pH of extracellular space serves as a cue to regulate a myriad of physiological activities,including ion transport,growth,and defense(Tsai and Schmidt,2021).Although it is known that the alkalization or acidification of apoplast is involved in cellular processes such as auxin-mediated cell elongation and pattern-triggered immunity,the molecular mechanism of extracellular pH perception remains unknown.This long-standing question was addressed recently by a research group led by Prof.Hongwei Guo from the Southern University of Science and Technology,China.The team(Liu et al.,2022)used molecular,biochemical,structural,and genetic analyses and revealed the indispensable role of peptide-receptor complexes in pH sensing in Arabidopsis root apical meristem(RAM)(Figure 1). | M.Arif Ashraf Mohammad Aslam | 2022 | Molecular Plant2022，15，10： | 0 |
| 17 | Natural contamination of human hands with enteric parasites in Indian Subcontinent显示文摘AIM: To investigate the prevalence of enteric parasite contamination on hands and the potential role naturally contaminated hands may have in their transmission. METHODS: Prior to initiating the survey, the protocol was reviewed and approved by respective Institutional Review Boards of each survey site(Dhaka, Bangladesh and Kolkata, India). Both stool and corresponding hand wash samples collected, were analyzed for the presence of enteric parasitic ova/(oo)cysts employing conventional microscopy coupled with permanent staining techniques. Additionally molecular approachessuch as polymerase chain reaction(PCR) of enteric parasites recovered from both stool and corresponding hand wash samples, were also used to further confirm their identity. RESULTS: A total of 972 stool samples were collected from both sites surveyed(300 volunteers from Kolkata, India and 672 from Dhaka, Bangladesh). Parasitic analysis revealed, 113(38%) from Kolkata, India and 267(40%) of stool samples from Dhaka, Bangladesh were positive for parasitic ova/(oo)cysts. When the corresponding hand wash samples were analyzed, 43(14%) stool-positive volunteers in Kolkata, India and 47(7%) in Dhaka, Bangladesh were positive for enteric parasitic ova/(oo)cysts. Ascaris lumbricoides(A. lumbricoides) ova and Giardia lamblia(G. lamblia) cysts predominated in hands wash samples from both sites surveyed(from India, A. lumbricoides ova, 53%; G. lamblia cysts 31% and from Bangladesh, A. lumbricoides ova, 47%; G. lamblia cysts 19%). Genotypic analysis of enteric parasitic ova/(oo)cysts obtained from both stool and corresponding hand wash samples taken from the same person were found to be identical. CONCLUSION: These results suggest a possible role of hands contaminated with enteric parasites' ova/(oo)cysts in the transmission of these parasites highlighting another role of hand hygiene/proper hand washing in reducing the disease burden in low socioeconomic communities. | M Khalid Ijaz Kaisar A Talukder Mohammad Aslam Rashidul Haque Sandipan Ganguly Ishrat J Azmi Md Shawkat Hossain Avik Kumar Mukherjee Dibyendu Raj Ijaz Ahmed Jabeen Kamal Joseph R Rubino Alam Nur-E-Kamal | 2013 | World Journal of Clinical Infectious Diseases2013，3，2： | 0 |
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