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| 1 | MicroRNA in TLR signaling and endotoxin tolerance显示文摘Toll-like receptors(TLRs)in innate immune cells are the prime cellular sensors for microbial components.TLR activation leads to the production of proinflammatory mediators and thus TLR signaling must be properly regulated by various mechanisms to maintain homeostasis.TLR4-ligand lipopolysaccharide(LPS)-induced tolerance or cross-tolerance is one such mechanism,and it plays an important role in innate immunity.Tolerance is established and sustained by the activity of the microRNA miR-146a,which is known to target key elements of the myeloid differentiation factor 88(MyD88)signaling pathway,including IL-1 receptor-associated kinase(IRAK1),IRAK2 and tumor-necrosis factor(TNF)receptor-associated factor 6(TRAF6).In this review,we comprehensively examine the TLR signaling involved in innate immunity,with special focus on LPS-induced tolerance.The function of TLR ligand-induced microRNAs,including miR-146a,miR-155 and miR-132,in regulating inflammatory mediators,and their impact on the immune system and human diseases,are discussed.Modulation of these microRNAs may affect TLR pathway activation and help to develop therapeutics against inflammatory diseases. | Md A Nahid Minoru Satoh Edward KL Chan | 2011 | Cellular & Molecular Immunology2011，8，5： | 34 |
| 2 | SAP155-Mediated Splicing of FUSE-Binding Protein-Interacting Repressor Serves as a Molecular Switch for c-myc Gene Expression显示文摘 | Kazuyuki Matsushita Toshiko Kajiwara Mai Tamura Mamoru Satoh Nobuko Tanaka Takeshi Tomonaga Hisahiro Matsubara Hideaki Shimada Rei Yoshimoto Akihiro Ito Shuji Kubo Tohru Natsume David Levens Minoru Yoshida Fumio Nomura | 2012 | Molecular Cancer Research2012，，6： | 2 |
| 3 | Demonstration of elevation and localization of Rho-kinase activity in the brain of a rat model of cerebral infarction显示文摘 | Kazuo Yano Koh Kawasaki Tsuyoshi Hattori Shunsuke Tawara Yoshinori Toshima Ichiro Ikegaki Yasuo Sasaki Shin-ichi Satoh Toshio Asano Minoru Seto | 2008 | European Journal of Pharmacology2008，，1： | 1 |
| 4 | 烧结技术的最新发展——高还原性及低热耗烧结矿的生产显示文摘 | Yasushi Ishikawa Masashi Kase Minoru Sasaki Katsuhiko Satoh Seigi Sasaki 邓庆球 | 1983 | 烧结球团1983，，02： | 1 |
| 5 | Actions of taurine on the L-type Ca2+ channel current in guinea pig ventricular cardiomyocytes显示文摘 | Hiroyasu Satoh Minoru Horie | 1997 | J Cardiovasc Pharmacol1997，30，： | 1 |
| 6 | Distribution and retention of mercury in metallothionein-null mice after exposure to meremy vapor 显示文摘 | Minoru Yoshida Masahiko Satoh | 1999 | Toxicology1999，139，： | 1 |
| 7 | Autoanti- body to NA14 is an independent marker primarily for Sj~gren's syndrome显示文摘 | Kazuhisa Nozawa Keigo Ikeda Minoru Satoh | 2010 | Front Biosci2010，14，5： | 1 |
| 8 | Enhanced TGF-b/Smad signaling in the early stage of diabetic nephropathy is independent of the AT1a receptor显示文摘 | Yuko Okazaki Yasushi Yamasaki Haruhito A. Uchida Kazunori Okamoto Minoru Satoh Keisuke Maruyama Yohei Maeshima Hitoshi Sugiyama Takeshi Sugaya Naoki Kashihara Hirofumi Makino | 2007 | Clinical and Experimental Nephrology2007，，1： | 1 |
| 9 | Upregulat- ed miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients 显示文摘 | Kaleb M Pauley Minoru Satoh Annie L Chan | 2008 | Arthritis Research and Therapy2008，10，4： | 1 |
| 10 | Klotho protects a- gainst mouse renal fibrosis by inhibiting Writ signaling显示文摘 | Minoru Satoh Hajime Nagasu Morita Y | 2012 | Am J Physiol Renal Physiol2012，15，： | 1 |
| 11 | NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy 显示文摘 | Minoru Satoh Sohachi Fujimoto Yoshisuke Haruna | 2005 | Am J Physiol-Renal2005，288，6： | 1 |
| 12 | Distribution and retention of mercury in metallothionein-null mice after exposure to mercury vapor显示文摘 | Minoru Yoshida Masahiko Satoh Akira Yasutake | 1999 | Toxicology1999，139，： | 1 |
| 13 | Establishment of a Blood Purification System for Renal Failure Rats Using Small - Size Dialyzer Membranes 显示文摘 | Daisuke Yorimitsu Minoru Satoh Masabide Koremoto | 2012 | Therapeutic Apheresis and Dialysis2012，10，6： | 1 |
| 14 | Endothelial dysfunction as an underlying pathophysiological condition of chronic kidney disease显示文摘 | Minoru Satoh | 2012 | Clinical and Experimental Nephrology2012，，4： | 1 |
| 15 | Evaluation of valid nil-ductility transition temperatures for nuclear vessel steels显示文摘 | Satoh M Funada T Minoru Tomimatsu | 1986 | ASTM STP1986，919，： | 1 |
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