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| 1 | Analysis of inversion error characteristics of stellar occultation simulation data显示文摘Atmospheric stellar occultation observation technology is an advanced space-based detection technology that can measure the vertical distribution of trace gas composition,temperature,and aerosol content in a planet’s atmosphere.In this study,an inversion algorithm of the onion-peeling method was constructed to invert the transmittance obtained from the forward mask.The method used a three-dimensional ray-tracing simulation to obtain the transmission path of the light in the Earth’s atmosphere.The relevant parameters were then combined in the high-resolution transmission molecular absorption(HITRAN)database,and line-by-line integration was performed to calculate the atmospheric transmittance.The transmittance value was then used as an input to calculate the vertical distribution of oxygen molecules when using the single-wavelength inversion of the onion-peeling method.Finally,the oxygen molecule content was compared with the value attained by the Mass Spectrometer and Incoherent Scatter Radar Extended(MSISE00)atmospheric model to determine the relative error of our model.The maximum error was found to be 0.3%,which is low enough to verify the reliability of our algorithm.Using Global-scale Observations of the Limb and Disk(GOLD)measured data to invert the oxygen number density,we calculated its relative deviation from the published result to further verify the algorithm.The inversion result was affected by factors such as prior data,the absorption spectral line type,the ellipticity of the Earth,and the accuracy of the orbit.Analysis of these error-influencing factors showed that the seasons and the Earth’s ellipticity affected the accuracy of the model only 0.001%and could therefore be ignored.However,latitude and solar activity had a greater impact on accuracy,on the order of 0.1%.The absorption line type affected the accuracy of the model by as much as 1%.All three of these factors therefore need to be considered during the inversion process. | MingChen Sun QingLin Zhu Xiang Dong JiaJi Wu | 2022 | Earth and Planetary Physics2022,6,1: | 1 |
| 2 | Application of Guizhi Fuling Pill in Gynecology显示文摘This paper reviews the research progress of Guizhi Fuling Pill in the clinical application of gynecology,such as the treatment of uterine leiomyoma,ovarian cyst,infertility and dysmenorrhea,in order to provide further research ideas for clinical researchers. | Gang LI Mingchen ZHU | 2024 | Medicinal Plant2024,15,2: | 0 |
| 3 | Multifunctional Gd-CuS loaded UCST polymeric micelles for MR/PA imaging-guided chemo-photothermal tumor treatment显示文摘Hepatocellular carcinoma(HCC)is a life-threatening disease for which there is no effective treatment currently.Novel theranostics simultaneously having excellent imaging and therapeutic functions are highly desired in cancer therapy.Herein,we develop the sialic acid(SA)modified polymeric micelles at an upper critical solution temperature(UCST)of 43℃(sialic acid-poly(ethylene glycol)-poly(acrylamide-co-acrylonitrile),SA-PEG-p(AAm-co-AN)),which further encapsulated with doxorubicin(DOX)and Gd-CuS nanoparticles(Gd-CuS NPs)for chemo-photothermal treatment of HCC guided by magnetic resonance(MR)/photoacoustic(PA)dual-mode imaging.The resultant SA-PEG-p(AAm-co-AN)/DOX/Gd-CuS(SPDG)had an excellent photothermal conversion efficiency,enabling SPDG with an instantaneous release behavior of DOX under near-infrared(NIR)irradiation.This study also revealed that SPDG could actively target to HCC,which was due to that SA had a high affinity with E-selectin overexpressed at the tumor site.Moreover,benefiting from the HCC-targeted ability and NIR light-controlled on-demand delivery of DOX,SPDG showed a superior potential in MR/PA dual-mode imaging-guided chemo-photothermal treatment.Overall,our study reveals that the designed SPDG may be used as an ideal multifunctional nanoplatform for cancer theranostics. | Yan Du Di Liu Mingchen Sun Gaofeng Shu Jing Qi Yuchan You Yiting Xu Kai Fan Xiaoling Xu Feiyang Jin Jun Wang Qiying Shen Luwen Zhu Xiaoying Ying Jiansong Ji Liming Wu Daren Liu Yongzhong Du | 2022 | Nano Research2022,15,3: | 0 |
| 4 | An investigation of long-term outcome of rabbit anti-thymocyte globulin and cyclosporine therapy for pediatric severe aplastic anemia显示文摘Children with severe aplastic anemia(SAA)face heterogeneous prognoses after immunosuppressive therapy(IST).There are few models that can predict the long-term outcomes of IST for these patients.The objective of this paper is to develop a more effective prediction model for SAA prognosis based on clinical electronic medical records from 203 children with newly diagnosed SAA.In the early stage,a novel model for long-term outcomes of SAA patients with IST was developed using machine-learning techniques.Among the indicators related to long-term efficacy,white blood cell count,lymphocyte count,absolute reticulocyte count,lymphocyte ratio in bone-marrow smears,C-reactive protein,and the level of IL-6,IL-8 and vitamin B12 in the early stage are strongly correlated with long-term efficacy(P<.05).Taken together,we analyzed the long-term outcomes of rabbit antithymocyte globulin and cyclosporine therapy for children with SAA through machine-learning techniques,which may shorten the observation period of therapeutic effects and reduce treatment costs and time. | Lixian Chang Mingchen Yan Jingliao Zhang Binghang Liu Li Zhang Ye Guo Jing Sun Yang Wan Meihui Yi Yang Lan Yuli Cai Yuanyuan Ren Haihui Zheng Aoli Zhang Zhenyu Li Jian Wang Yingrui Li Xiaofan Zhu | 2023 | Blood Science2023,5,3: | 0 |
| 5 | A Novel Multi-Granularity Flexible-Grid Switching Optical-Node Architecture显示文摘A novel multi-granularity flexible-grid switching optical-node architecture is proposed in this paper.In our system,the photonic lanterns are used as mode division multiplexing/demultiplexing(MD-Mux/MD-Demux)for selecting mode.The wavelength division multiplexer/demultiplexer(WDMux/WD-Demux)and the fiber bragg gratings(FBGs)are used to select wavelength channels with the various grid.The experimental results show that the transmission bandwidth covers the C+L band,the average transmission loss is-13.4 dB,and the average crosstalk is-30.5 dB.The optical-node architecture is suit for mode division multiplexing(MDM)optical communication system. | Zhenfang Huang Bo Zhu Mingchen Zhu Mengyue Jiang Xinting Song Jiawei Zhao Zheng Wang Fangren Hu | 2023 | China Communications2023,20,1: | 0 |