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| 1 | China land soil moisture EnKF data assimilation based on satellite remote sensing data显示文摘Soil moisture plays an important role in land-atmosphere interactions. It is an important geophysical parameter in research on climate, hydrology, agriculture, and forestry. Soil moisture has important climatic effects by influencing ground evapotranspi ration, runoff, surface reflectivity, surface emissivity, surface sensible heat and latent heat flux. At the global scale, the extent of its influence on the atmosphere is second only to that of sea surface temperature. At the terrestrial scale, its influence is even greater than that of sea surface temperatures. This paper presents a China Land Soil Moisture Data Assimilation System (CLSMDAS) based on EnKF and land process models, and results of the application of this system in the China Land Soil Moisture Data Assimilation tests. CLSMDAS is comprised of the following components: 1) A land process mo del—Community Land Model Version 3.0 (CLM3.0)—developed by the US National Center for Atmospheric Research (NCAR); 2) Precipitation of atmospheric forcing data and surface-incident solar radiation data come from hourly outputs of the FY2 geostationary meteorological satellite; 3) EnKF (Ensemble Kalman Filter) land data assimilation method; and 4) Observa tion data including satellite-inverted soil moisture outputs of the AMSR-E satellite and soil moisture observation data. Results of soil moisture assimilation tests from June to September 2006 were analyzed with CLSMDAS. Both simulation and assimila tion results of the land model reflected reasonably the temporal-spatial distribution of soil moisture. The assimilated soil mois ture distribution matches very well with severe summer droughts in Chongqing and Sichuan Province in August 2006, the worst since the foundation of the People’s Republic of China in 1949. It also matches drought regions that occurred in eastern Hubei and southern Guangxi in September. | SHI ChunXiang XIE ZhengHui QIAN Hui LIANG MiaoLing YANG XiaoChun | 2011 | Science China Earth Sciences2011，54，9： | 62 |
| 2 | A novel STING agonist-adjuvanted pan-sarbecovirus vaccine elicits potent and durable neutralizing antibody and T cell responses in mice,rabbits and NHPs显示文摘The emergence of SARS-CoV-2 variants and potentially other highly pathogenic sarbecoviruses in the future highlights the need for pan-sarbecovirus vaccines.Here,we discovered a new STING agonist,CF501,and found that CF501-adjuvanted RBD-FC vaccine(CF501/RBD-FC)elicited significantly stronger neutralizing antibody(nAb)and T cell responses than Alum-and cGAMP-adjuvanted RBD-FC in mice.Vaccination of rabbits and rhesus macaques(nonhuman primates,NHPs)with CF501/RBD-FC elicited exceptionally potent nAb responses against SARS-CoV-2 and its nine variants and 41 S-mutants,SARS-CoV and bat SARSr-CoVs.CF501/RBD-FC-immunized hACE2-transgenic mice were almost completely protected against SARS-CoV-2 challenge,even 6 months after the initial immunization.NHPs immunized with a single dose of CF501/RBD-FC produced high titers of nAbs.The immunized macaques also exhibited durable humoral and cellular immune responses and showed remarkably reduced viral load in the upper and lower airways upon SARS-CoV-2 challenge even at 108 days post the final immunization.Thus,CF501/RBD-Fc can be further developed as a novel pan-sarbecovirus vaccine to combat current and future outbreaks of sarbecovirus diseases. | Zezhong Liu Jie Zhou Wei Xu Wei Deng Yanqun Wang Meiyu Wang Qian Wang Ming Hsieh Jingming Dong Xinling Wang Weijin Huang Lixiao Xing Miaoling He Chunlin Tao Youhua Xie Yilong Zhang Youchun Wang Jincun Zhao Zhenghong Yuan Chuan Qin Shibo Jiang Lu Lu | 2022 | Cell Research2022，32，3： | 5 |
| 3 | The Infiltration Process and Texture Transition of 2D C/C Composites显示文摘2D needle-punched fiber felt was infiltrated by a kind of rapid isothermal chemical vapor infiltration technique. The infiltration process and texture transition of the infiltrated C/C composites were investigated. The porosity and the variations of the cumulative pore volume were determined by mercury porosimetry. The texture of matrix carbon was studied under a polarized light microscope. The results show that the relative mass gain of the sample increases directly as the infiltration time at the initial stage until 20 h, and subsequently the increasing rate of the relative mass gain decreases gradually with the prolonging of infiltration time. Three layers of pyrocarbon were formed around fibers. Low-textured pyrocarbon was obtained at the initial stage. With the densification going on, high-textured pyrocarbon was formed on the surface of low-textured pyrocarbon. Then, low-textured pyrocarbon was produced again during the final stage of densification. The texture transition is ascribed to the variation of the ratio of cumulative inner surface area to volume of pores and the gas partial pressure in pores. | Hejun Li Guozhong Xu Kezhi Li Chuang Wang Wei Li Miaoling Li | 2009 | Journal of Materials Science & Technology2009，25，1： | 2 |
| 4 | Role of calcium mobilization in the regulation of spontaneous transient outward currents in porcine coronary artery myocytes显示文摘The purpose of the present study was to further study the characteristics and regulation of spontaneous transient outward currents (STOCs) in freshly isolated porcine coronary artery smooth muscle cells (ASMCs). STOCs were recorded using the perforated whole-cell patch-clamp configuration. STOCs were voltage-dependent and superimposed stochastically onto whole-cell Ca2+-activated-K+ (BKCa) currents. Charybdotoxin (ChTX, 200 nmol/L), a selective blocker of BKCa channels, completely inhibited STOCs within 10 min. STOCs activity was greatly suppressed when extracellular Ca2+ concentration decreased from 1.8 mmol/L to 200 nmol/L, further removal of Ca2+ abolished STOCs activity. Ca2+ ionophore A23187 (10 μmol/L) increased STOCs activity significantly. Verapamil (20 μmol/L) and CdCl2 (200 μmol/L), two kinds of organic L-type voltage-dependent Ca2+ channels (L-VDCCs) antagonists, had little effect on STOCs. In addition, the ryanodine receptors (RyRs) agonist caffeine (5 mmol/L) significantly activated STOCs. Application of ryanodine (50 μmol/L) to block RyRs abolished STOCs, subsequent washout of ryanodine or application of caffeine failed to reproduce STOCs activity. Inhibition of inositol 1,4,5-trisphosphate receptors (IP3Rs) by 2APB (40 μmol/L) greatly suppressed the activity of STOCs, application of caffeine (5 mmol/L) in the presence of 2APB caused a burst of outward currents followed by inhibition of STOCs. These results suggest that STOCs in porcine coronary ASMCs are mediated by BKCa channels. Extracellular Ca2+ is essential for STOCs activity, while Ca2+ entry through L-VDCCs has little effect on STOCs. Intracellular Ca2+ release induced by RyRs is responsible for the regulation of STOCs, whereas IP3Rs might also be involved. | LI PengYun ZENG XiaoRong YANG Yan CAI Fang LIU ZhiFei LI MiaoLing PEI Jie ZHOU Wen | 2007 | Science China(Life Sciences)2007，50，5： | 1 |
| 5 | Measurement of the extinction angle about laminar pyrocarbons by image analysis in reflection polarized light 显示文摘 | Li Miaoling Qi Lehua Li Heiun Xu Guozhong | 2007 | Materials Science and Engineering A2007，448，12： | 1 |
| 6 | Chemical composition and antimicrobial activities of essential oil from the peel of bingtang sweet orange (Citrus sinensis Osbeck)显示文摘 | TAO Nengguo LIU Yuejin ZHANG Miaoling | 2009 | Int J Food Sci Tech2009，44，7： | 1 |
| 7 | Specific Regulation of m^(6)A by SRSF7 Promotes the Progression of Glioblastoma显示文摘Serine/arginine-rich splicing factor 7(SRSF7),a known splicing factor,has been revealed to play oncogenic roles in multiple cancers.However,the mechanisms underlying its oncogenic roles have not been well addressed.Here,based on N6-methyladenosine(m^(6)A)co-methylation network analysis across diverse cell lines,we find that the gene expression of SRSF7 is positively correlated with glioblastoma(GBM)cell-specific m^(6)A methylation.We then indicate that SRSF7 is a novel m^(6)A regulator,which specifically facilitates the m^(6)A methylation near its binding sites on the mRNAs involved in cell proliferation and migration,through recruiting the methyltransferase complex.Moreover,SRSF7 promotes the proliferation and migration of GBM cells largely dependent on the presence of the m^(6)A methyltransferase.The two m^(6)A sites on the mRNA for PDZ-binding kinase(PBK)are regulated by SRSF7 and partially mediate the effects of SRSF7 in GBM cells through recognition by insulin-like growth factor 2 mRNA-binding protein 2(IGF2BP2).Together,our discovery reveals a novel role of SRSF7 in regulating m^(6)A and validates the presence and functional importance of temporal-and spatial-specific regulation of m^(6)A mediated by RNA-binding proteins(RBPs). | Yixian Cun Sanqi An Haiqing Zheng Jing Lan Wenfang Chen Wanjun Luo Chengguo Yao Xincheng Li Xiang Huang Xiang Sun Zehong Wu Yameng Hu Ziwen Li Shuxia Zhang Geyan Wu Meisongzhu Yang Miaoling Tang Ruyuan Yu Xinyi Liao Guicheng Gao Wei Zhao Jinkai Wang Jun Li | 2023 | Genomics, Proteomics & Bioinformatics2023，21，4： | 1 |
| 8 | Geochronology and geochem-istry of the Hegenshan ophiolitic complex: Implications for late-stage tectonic evolution of the Inner Mongolia- Daxing'anlingOrogenic Belt, China 显示文摘 | MiaoL C Fan W M Liu D Y | 2008 | Journal of Asian Earth Sciences2008，32，： | 1 |
| 9 | Lattice vibration and Raman scattering of two-dimensional van der Waals heterostructure显示文摘Research on two-dimensional(2D) materials and related van der Waals heterostructures(vdWHs) is intense and remains one of the leading topics in condensed matter physics.Lattice vibrations or phonons of a vdWH provide rich information,such as lattice structure,phonon dispersion,electronic band structure and electron–phonon coupling.Here,we provide a mini review on the lattice vibrations in vdWHs probed by Raman spectroscopy.First,we introduced different kinds of vdWHs,including their structures,properties and potential applications.Second,we discussed interlayer and intralayer phonon in twist multilayer graphene and MoS2.The frequencies of interlayer and intralayer modes can be reproduced by linear chain model(LCM)and phonon folding induced by periodical moiré potentials,respectively.Then,we extended LCM to vdWHs formed by distinct 2D materials,such as MoS2/graphene and hBN/WS2 heterostructures.We further demonstrated how to calculate Raman intensity of interlayer modes in vdWHs by interlayer polarizability model. | Xin Cong Miaoling Lin Ping-Heng Tan | 2019 | Journal of Semiconductors2019，40，9： | 1 |
| 10 | On3-choosabilityofplanegraphswithout3-,8-and9-cycles显示文摘 | ZhuX MiaoL WangC | 2007 | AustralasJComb2007，38，： | 1 |
| 11 | Contribution of age, body weight, and CYP2C9 and VKORC1 genotype to the anticoagulant response to warfarin: proposal for a new dosing regimen in Chinese Datients显示文摘 | MiaoL YangJ Huang C | 2007 | Eur J Clin Pharmacol2007，63，12： | 1 |
| 12 | Prognostic significance of cyclooxygenase‐2 in cervical cancer: A meta‐analysis显示文摘 | Miaoling Huang Qing Chen Jianpeng Xiao Changhao Liu Xiaomiao Zhao | 2012 | Int J Cancer2012，，2： | 1 |
| 13 | CircRNA ATF6 promotes ovarian cancer cell progression by activating PTEN/mTOR signaling pathway显示文摘Ovarian cancer is a malignant cancer type and affects women’s lives in the world.Circular RNAs(circRNAs)have been involved with the progression of cancers.In our study,we are going to explore the functions of circATF6 in ovarian cancer.The qRT-PCR assay was used to detect expressions of genes.Actinomycin D and RNase R treatment were implemented to verify the circular RNA character of circATF6.Besides,Cell proliferation was assessed by colony formation assay and EdU assay.Silenced circATF6 could reduce the proliferation of ovarian cancer cells.In addition,inhibited circATF6 could promote the cell apoptosis and inhibit related proteins in PTEN/mTOR signaling pathway in ovarian cancer.In conclusion,CircRNA ATF6 promotes ovarian cancer cell progression by activating PTEN/mTOR signaling pathway. | LIETING MA MIAOLING LI XINGLONG ZHENG | 2021 | BIOCELL2021，45，2： | 1 |
| 14 | Identifying target green 3C customer in Taiwan using multi-attribute utility theory 显示文摘 | Wang Miaoling Kuo T C | 2009 | Expert Systems with Applications2009，36，12： | 1 |
| 15 | 显示文摘 | 万厚钊(WanHZ) 缪灵(MiaoL) 徐葵(XuK) 亓同(QiT) 江建军(JiangJJ) | 2013 | 化工学报2013，64，： | 1 |
| 16 | An imaging technique using rotational polarization microscopy for the microstrueture analysis of carbon/carbon composites显示文摘 | Miaoling L Lehua Q Hejun L | 2012 | Microscopy research and technique2012，75，1： | 1 |
| 17 | Chry- somya megaeephala (Fabricius) larvae:A new biodiesel resource显示文摘 | Li Zhuoxue Yang Depo Miaoling Huang | 2012 | Applied Energy2012，94，： | 1 |
| 18 | Fractal characterization of pore microstructure evolution in carbon/carbon composites显示文摘A fractal characterization approach was proposed to research pore microstructure evolution in car- bon/carbon (C/C) composites during the chemical vapor infiltration process. The data obtained from mercury porosimetry determinations were analyzed using the sponge fractal model and the thermo- dynamics relation fractal model, respectively. The fractal dimensions of C/C composites at different densification stages were evaluated. The pore microstructure evolution with densification time was studied by fractal dimension analysis. The results showed that C/C composites belong to porous frac- tal structure. The fractal dimensions increase on the whole with decreasing porosity as the densifica- tion proceeds. The fractal dimensions are influenced by the texture of pyrocarbon and decrease with increasing anisotropy from isotropic pyrocarbon to high textural one. Both the complicacy of pore structure and the textural morphology of pyrocarbon can be represented simultaneously by the fractal dimension. The pore evolution of C/C composites in the densification process can be monitored using fractal dimension. | LI MiaoLing QI LeHua LI HeJun XU GuoZhong | 2009 | Science China(Technological Sciences)2009，52，4： | 1 |
| 19 | Oxygen-assisted preparation of mechanoluminescent ZnS:Mn for dynamic pressure mapping显示文摘变换机械刺激点亮排放的 Mechanoluminescent 材料在人机器的相互作用为潜在的应用吸引了广泛的注意。这里,我们为 ZnS 的帮助氧的准备报导一条简单、可得到的新奇途径: Mn 粒子由固态在没有相应氧化物的形成的气压的反应。O 2 的存在在 wurtzite 阶段 ZnS 在 S 空缺的形成上有积极影响,导致 Mn 2+ 离子的介绍光中心和浅施主铺平,它能改进电子洞再结合率。O 2 比率和 Mn 2+ 离子做集中在发光效率上有重要效果,它分别地在 1%-20% 和 1 at.%-2 at.% 是最佳的。另外,一台设备基于有 0.032 MPa 1 的优秀压力敏感的 piezo-photonic 效果被制作,它能印射在 situ 从 2.2 ~ 40.6 MPa 的二维的压力分发。这台设备能被用于即时压力印射,聪明的传感器网络,高级安全系统,人机器的接口,和人工的皮肤。 | Xiandi Wang Rui Ling Yufei Zhang Miaoling Que Yiyao Peng Caofeng Pan | 2018 | Nano Research2018，11，4： | 1 |
| 20 | A Comprehensive Bibliometric Analysis of China’s Free Trade Zones:Status and Evolutionary Trends显示文摘The China free trade zone,crucial for advancing a new open economy,has gained significant attention lately.We analyzed 885 papers from Peking University Core and CSSCI journals(2012-2023)using CiteSpace for visualization.Our research results indicate that the literature on China’s free trade zone peaked with 171 articles in 2015,and gradually returned to an average of 45 articles per year.The main research focuses in this field include“institutional innovation”,“negative list”,“financial innovation”,“financial openness”,“opening up to the outside world”,and“economic growth”.In addition,cutting-edge analysis indicates that“dual circulation”and“blockchain”are future research trends.The main authors of the literature include Yang Bin,Zhu Xiaolin,Yuan Bo,Li Meng,Zhao Liang,and others.Their affiliated institutions,research institutes,and universities have not yet formed a clear core circle of authors;The top three research institutions with the highest number of publications are the International Trade and Economic Cooperation Research Institute of the Ministry of Commerce,Kaiyuan Law School of Shanghai Jiao Tong University,and the Comprehensive Research Institute of the Free Trade Zone of Sun Yatsen University.This article delves into the current hot topics and progress in the research of China’s free trade zones,providing important references and inspirations for future scholars in this field. | HUANG Lixia XU Miaoling | 2023 | Chinese Business Review2023，22，3： | 0 |
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