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| 1 | A matched-pair analysis of laparoscopic versus open pancreaticoduodenectomy: oncological outcomes using Leeds Pathology Protocol显示文摘BACKGROUND: Laparoscopic pancreaticoduodenectomy(LPD)is a safe procedure. Oncological safety of LPD is still a matter for debate. This study aimed to compare the oncological outcomes,in terms of adequacy of resection and recurrence rate following LPD and open pancreaticoduodenectomy(OPD).METHODS: Between November 2005 and April 2009, 12LPDs(9 ampullary and 3 distal common bile duct tumors)were performed. A cohort of 12 OPDs were matched for age,gender, body mass index(BMI) and American Society of Anesthesiologists(ASA) score and tumor site.RESULTS: Mean tumor size LPD vs OPD(19.8 vs 19.2 mm,P=0.870). R0 resection was achieved in 9 LPD vs 8 OPD(P=1.000). The mean number of metastatic lymph nodes and total number resected for LPD vs OPD were 1.1 vs 2.1(P=0.140)and 20.7 vs 18.5(P=0.534) respectively. Clavien complications grade I/II(5 vs 8), III/IV(2 vs 6) and pancreatic leak(2 vs 1)were statistically not significant(LPD vs OPD). The mean high dependency unit(HDU) stay was longer in OPD(3.7 vs 1.4 days,P<0.001). There were 2 recurrences each in LPD and OPD(logrank,P=0.983). Overall mortality for LPD vs OPD was 3 vs 6(log-rank, P=0.283) and recurrence-related mortality was 2 vs 1.There was one death within 30 days in the OPD group secondary to severe sepsis and none in the LPD group.CONCLUSIONS: Compared to open procedure, LPD achieved a similar rate of R0 resection, lymph node harvest and longterm recurrence for tumors less than 2 cm. Though technically challenging, LPD is safe and does not compromise oncological outcome. | Abdul R Hakeem Caroline S Verbeke Alison Cairns Amer Aldouri Andrew M Smith Krishna V Menon | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，4： | 24 |
| 2 | Overexpression of E2F-1 in lung and liver metastases of human colon cancer is associated with gene amplification显示文摘 | Iwamoto M Banerjee D Menon LG | 2004 | Cancer Biol Tber2004，3，4： | 1 |
| 3 | Resting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus显示文摘 | Greicius M D Flores B H Menon V | 2007 | Biol Psychiatry2007，62，5： | 1 |
| 4 | Gender differences in cardiac function during early remodeling after acute myocardial infarction in mice显示文摘 | CAVASIN M A TAO Z MENON S | 2004 | Life Sei2004，75，18： | 1 |
| 5 | Structureand stability of Ni-encapsulated Si nanotube显示文摘 | MENON M ANDRIOTIS A N FROUDAKIS G | 2002 | Nano Lett2002，2，4： | 1 |
| 6 | Tear film lipid layer thickness and ocular comfort after meibomian therapy via latent heat with a novel device in normal subjects 显示文摘 | Mitra M Menon GJ Casini A | 2005 | Eye2005，19，6： | 1 |
| 7 | (31 Integrins expression in adult rat ventricular myocytes and itsrole in the regulation of beta-adrenergic receptor-stimulated ap-optosis显示文摘 | Communal C Singh M Menon B Xie Z Colucci W S Singh K | 2003 | J Cell Biochem2003，89，： | 1 |
| 8 | Introduction of enteral feeds in preterm infants显示文摘 | Menon G Boylee M Embleton ND | 2004 | Pediatrics2004，114，1： | 1 |
| 9 | Complications asmciated with the bacille Calmette-Guérin vaccination in Ireland显示文摘 | Bolger T O'Connell M Menon A | | 0，，07： | 1 |
| 10 | Autoimmune thyroid dis- ease in Indian children with type 1 diabetes mellitus显示文摘 | Menon PS Vaidyanathan B Kaur M | 2001 | J Pediatr Endocrinol Metab2001，14，3： | 1 |
| 11 | A comparison of scalar PDF turbulent combustion models 显示文摘 | G M Goldin S Menon | 1998 | Combustion and Flame1998，113，： | 1 |
| 12 | Effect of a short CAG (glu tamine) repeat on human androgen receptor function显示文摘 | Ding D Xu L Menon M | 2004 | Prostate2004，58，1： | 1 |
| 13 | Mechanism of stone formation显示文摘 | Balaji K C Menon M | 1997 | Urol Clin North Am1997，24，1： | 1 |
| 14 | Shear-modulusestimation by application of spatially-modulated impulsive acoustic radiation force显示文摘 | McAleavey SA Menon M Orszulak J | | 0，，： | 1 |
| 15 | Differences in the placental membrane cytokine response:apossible explanation for the racial disparity in preterm birth显示文摘 | Menon R Merialdi M Lombardi SJ | 2006 | Am J Reprod Immunol2006，56，2： | 1 |
| 16 | Monoeytic Myeloid - Derived Suppressor Ceils Accumulate in Renal Transplant Patients and Mediate CD4 + Foxp3 + Treg Expansion显示文摘 | Luan Y Mosheir E Menon M | 2013 | American journal of transplantation2013，13，12： | 1 |
| 17 | The Technique of Apical Dissection of the Prostate and Urethrovesical Anastomosis in Robotic Radical Prostatectomy显示文摘 | Menon M Hemal A K Tewari A | 2004 | BJU Int2004，93，： | 1 |
| 18 | Dendritic cells in colorectal cancer correlate with other tumor-infiltrating immune cells 显示文摘 | Dadabayev A R Sandel M H Menon A G | 2004 | Cancer Immunol Immunother2004，53，11： | 1 |
| 19 | Patient-cen- tered care for Muslim women:Provider and patient per- spectives显示文摘 | Hasnain M Connell K J Menon U | 2011 | J Womens Health (Larchmt)2011，20，1： | 1 |
| 20 | Temperature de- pendence of the electrical conductivity of imidazolium ionic liquids 显示文摘 | LEYS J W1DBBENHORST M MENON C P | 2008 | J Chem Phys2008，128，06： | 1 |
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