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| 1 | Clinical study using mesenchymal stem cells for the treatment of patients with severe COVID-19显示文摘The coronavirus disease 2019(COVID-19)caused by SARS-CoV-2 was identified in December 2019.The symptoms include fever,cough,dyspnea,early symptom of sputum,and acute respiratory distress syndrome(ARDS).Mesenchymal stem cell(MSC)therapy is the immediate treatment used for patients with severe cases of COVID-19.Herein,we describe two confirmed cases of COVID-19 in Wuhan to explore the role of MSC in the treatment of COVID-19.MSC transplantation increases the immune indicators(including CD4 and lymphocytes)and decreases the inflammation indicators(interleukin-6 and C-reactive protein).High-flow nasal cannula can be used as an initial support strategy for patients with ARDS.With MSC transplantation,the fracrion of inspired O2(Fi02)of the two patients gradually decreased while the oxygen saturation(Sa02)and partial pressure of oxygen(P02)improved.Additionally,the patients9 chest computed tomography showed that bilateral lung exudate lesions were adsorbed after MSC infusion.Results indicated that MSC transplantation provides clinical data on the treatment of COVID-19 and may serve as an alternative method for treating COVID-19,particularly in patients with ARDS. | Lingling Tang Yingan Jiang Mengfei Zhu Lijun Chen Xiaoyang Zhou Chenliang Zhou Peng Ye Xiaobei Chen Baohong Wang Zhenyu Xu Qiang Zhang Xiaowei Xu Hainv Gao Xiaojun Wu Dong Li Wanli Jiang Jingjing Qu Charlie Xiang Lanjuan Li | 2020 | Frontiers of Medicine2020，14，5： | 8 |
| 2 | A Promising Anti-Cytokine-Storm Targeted Therapy for COVID-19:The Artificial-Liver Blood-Purification System显示文摘The coronavirus disease 2019(COVID-19)pan-epidemic,resulting from infection with the 2019 novel coronavirus(2019-nCoV),also known as severe acute respiratory syndrome-coronavirus-2(SARS-CoV-2),is currently the source of public health concern worldwide;however,treatment of this infection has been clinically challenging in many patients[1].Importantly,2019-nCoV is the third fatal coronavirus that has emerged in the past two decades,following SARS-CoV and the Middle East respiratory syndrome(MERS)-CoV[2].The numbers of confirmed cases of COVID-19 infection and related deaths are still rising.As of 9 March 2020. | Yimin Zhang Liang Yu LingLing Tang Mengfei Zhu Yanqi Jin Zhouhan Wang Lanjuan Li | 2021 | Engineering2021，7，1： | 2 |
| 3 | Effect of CeO2 on crystal structures and catalytic properties of the Mn2O3 catalysts 显示文摘 | Zhu Bo | 1994 | Journal of Rare Earths1994，12，32： | 1 |
| 4 | Reducing surficial and interfacial defects by thiocyanate ionic liquid additive and ammonium formate passivator for efficient and stable perovskite solar cells显示文摘Organic–inorganic metal halide perovskites have attained extensive attention owing to their outstanding photovoltaic performances,but the existence of numerous defects in crystalline perovskites is still a serious constraint for the further development of perovskite solar cells(PSCs).In particular,the rapid crystallization guided by anti-solvents leads to plenty of surficial and interfacial defects in perovskite films.Herein,we report the adoption of a pseudo-halide anion based ionic liquid additive,1-butyl-3-methylimidazolium thiocyanate(BMIMSCN)for growing ternary cation(CsFAMA,where FA=formamidinium and MA=methylammonium)perovskites with large-scale crystal grains and strong preferential orientation via the enhanced Ostwald ripening.Meanwhile,a novel halide-free passivator,benzylammonium formate(BAFa),was employed as a buffering layer on the perovskite films to suppress surface-dominated charge recombination.As a result,the cooperative effects of BMIMSCN additive and BAFa passivator lead to significant enhancements on fluorescence lifetime(from 79.41 to 201.01 ns),open-circuit voltage(from 1.13 to 1.19 V),photoelectric conversion efficiency(from 18.90%to 22.33%).Moreover,the BMIMSCN/BAFa-CsFAMA PSCs demonstrated greatly improved stability against moisture and heat.This work suggests a promising strategy to improve the quality of perovskite materials via reducing the surficial and interfacial defects by the synergistic effects of lattice doping and interface engineering. | Mengfei Zhu Yuren Xia Lina Qin Kaiqiang Zhang Junchuan Liang Cheng Zhao Daocheng Hong Minghang Jiang Xinmei Song Jie Wei Pengbo Zhang Yuxi Tian Zhong Jin | 2023 | Nano Research2023，16，5： | 1 |
| 5 | The Incidence of Lymphoma in Beijing:Comparing Results from MIS-CASS(2019)and Beijing Cancer Registry(2017)显示文摘Introduction:This study aimed to evaluate the performance of the Medical-Insurance-System-based Cancer Surveillance System(MIS-CASS)in estimating cancer incidence by comparing the results with the Beijing Cancer Registry(BCR),which is one of the highest-quality population-based cancer registries in China.Methods:Using lymphoma as an example,we extracted relevant claims data from the administrative systems of medical insurance in Beijing(2012–2020)and estimated the most current lymphoma incidence in Beijing(2019)using a standard data processing procedure.The absolute number of new cases,crude incidence rate,and age-standardized incidence rate of lymphoma were compared with the latest data reported by the BCR(2017).Results:Both lymphoma incidence rates and age distribution of new cases estimated based on MISCASS were similar to the BCR data(crude incidence rate:9.8/100,000 vs.10.6/100,000).However,because MIS-CASS included more designated hospitals and covered a larger local stationary population irrespective of household registration(hukou),the absolute number of incident lymphoma cases identified by MIS-CASS was 39.1%higher than that reported by the BCR(2,002 vs.1,439).Conclusions:The MIS-CASS approach reflected the actual cancer burden in a more complete and timely manner as compared with the current BCR,providing new insights for improving cancer surveillance strategies in China. | Hongrui Tian Weiping Liu Yuqin Song Lan Mi Zhen Liu Mengfei Liu Chuanhai Guo Fangfang Liu Ying Liu Yaqi Pan Jun Zhu Zhonghu He Yang Ke | 2021 | China CDC weekly2021，3，52： | 0 |
| 6 | Antimony doped CsPbI_(2)Br for high-stability all-inorganic perovskite solar cells显示文摘All-inorganic perovskites,adopting cesium(Cs+)cation to completely replace the organic component of A-sites of hybrid organic–inorganic halide perovskites,have attracted much attention owing to the excellent thermal stability.However,all-inorganic iodine-based perovskites generally exhibit poor phase stability in ambient conditions.Herein,we propose an efficient strategy to introduce antimony(Sb^(3+))into the crystalline lattices of CsPbI_(2)Br perovskite,which can effectively regulate the growth of perovskite crystals to obtain a more stable perovskite phase.Due to the much smaller ionic radius and lower electronegativity of trivalent Sb^(3+)than those of Pb^(2+),the Sb^(3+)doping can decrease surface defects and suppress charge recombination,resulting in longer carrier lifetime and negligible hysteresis.As a result,the all-inorganic perovskite solar cells(PSCs)based on 0.25%Sb^(3+)doped CsPbI_(2)Br light absorber and screen-printable nanocarbon counter electrode achieved a power conversion efficiency of 11.06%,which is 16%higher than that of the control devices without Sb^(3+)doping.Moreover,the Sb^(3+)doped all-inorganic PSCs also exhibited greatly improved endurance against heat and moisture.Due to the use of low-cost and easy-to-process nanocarbon counter electrodes,the manufacturing process of the all-inorganic PSCs is very convenient and highly repeatable,and the manufacturing cost can be greatly reduced.This work offers a promising approach to constructing high-stability all-inorganic PSCs by introducing appropriate lattice doping. | Mengfei Zhu Lina Qin Yuren Xia Junchuan Liang Yaoda Wang Daocheng Hong Yuxi Tian Zuoxiu Tie Zhong Jin | 2024 | Nano Research2024，17，3： | 0 |
| 7 | A heuristic mixed real-time task allocation of virtual utilization in multi-core processor显示文摘Multi-core processor is widely used as the running platform for safety-critical real-time systems such as spacecraft,and various types of real-time tasks are dynamically added at runtime.In order to improve the utilization of multi-core processors and ensure the real-time performance of the system,it is necessary to adopt a reasonable real-time task allocation method,but the existing methods are only for single-core processors or the performance is too low to be applicable.Aiming at the task allocation problem when mixed real-time tasks are dynamically added,we propose a heuristic mixed real-time task allocation algorithm of virtual utilization VU-WF(Virtual Utilization Worst Fit)in multi-core processor.First,a 4-tuple task model is established to describe the fixedpoint task and the sporadic task in a unified manner.Then,a VDS(Virtual Deferral Server)for serving execution requests of fixed-point task is constructed and a schedulability test of the mixed task set is derived.Finally,combined with the analysis of VDS's capacity,VU-WF is proposed,which selects cores in ascending order of virtual utilization for the schedulability test.Experiments show that the overall performance of VU-WF is better than available algorithms,not only has a good schedulable ratio and load balancing but also has the lowest runtime overhead.In a 4-core processor,compared with available algorithms of the same schedulability ratio,the load balancing is improved by 73.9%,and the runtime overhead is reduced by 38.3%.In addition,we also develop a visual multi-core mixed task scheduling simulator RT-MCSS(open source)to facilitate the design and verification of multi-core scheduling for users.As the high performance,VU-WF can be widely used in resource-constrained and safety-critical real-time systems,such as spacecraft,self-driving cars,industrial robots,etc. | Hongbiao Liu Mengfei Yang Tingyu Wang Chenghao Song Shenghui Zhu Xi Chen | 2023 | Journal of Information and Intelligence2023，1，2： | 0 |
| 8 | Furan Donor for NIR-II Molecular Fluorophores with Enhanced Bioimaging Performance显示文摘The second near-infrared(NIR-II,1,000 to 1,700 nm)molecular fluorophores containing donor–acceptor–donor conjugated backbone have attracted substantial attention due to their outstanding advantages,such as stable emission and facilely tuned photophysical properties.However,it is still challenging for them to simultaneously achieve high brightness and red-shifted absorption and emission.Herein,furan is adopted as the D unit to construct NIR-II fluorophores,demonstrating red shift of absorption,enhanced absorption coefficient,and fluorescent quantum yield when compared with the generally used thiophene counterparts.The high brightness and desirable pharmacokinetics of the optimized fluorophore,IR-FFCHP,endows improved performance for angiography and tumor-targeting imaging.Furthermore,dual-NIR-II imaging of tumor and sentinel lymph nodes(LNs)has been achieved with IR-FFCHP and PbS/CdS quantum dots,enabling the in vivo imaging navigated LN surgery in tumor-bearing mice.This work demonstrates the potential of furan for constructing bright NIR-II fluorophores for biological imaging. | Chunchen Liu Mengfei Li Huilong Ma Zhubin Hu Xinyuan Wang Rui Ma Yingying Jiang Haitao Sun Shoujun Zhu Yongye Liang | 2023 | Research2023，，3： | 0 |
| 9 | Pulmonary Vein Stenosis:A Review显示文摘Pulmonary vein stenosis(PVS)is an extremely rare and lethal disease caused by multiple etiologies.PVS has a bimodal distribution in the population,affecting children and adults.Congenital PVS is the usual PVS type in children,which sometimes develops after cardiothoracic surgery.Acquired PVS,in turn,is the most common PVS type in adults.A review of the relevant literature has shown that PVS after radiofrequency ablation of atrial fibrillation is the most common,as well as that caused by compression of proliferative fibrous tissues or tumor in the mediastinum(eg,PVS caused by fibrosing mediastinitis,lung tumors,metastases,etc).This article provides a comprehensive review of PVS in terms of embryology and anatomy,etiology and triggers,classification,clinical symptoms and signs,treatment,and prognosis,intending to promote the understanding and treatment of this disease. | Mengfei Jia Juan Wang Kaiyu Jiang Hongling Su Yu Li Zhaoxia Guo Hai Zhu Aqian Wang Xin Pan Yunshan Cao | 2023 | Cardiology Discovery2023，3，2： | 0 |
| 10 | Biofabrication of aligned structures that guide cell orientation and applications in tissue engineering显示文摘The organized alignment of cells in various tissues plays a significant role in the maintenance of specific functions.To induce such an alignment,ideal scaffolds should simulate the characteristics and morphologies of natural tissues.Aligned structures that guide cell orientation are used to facilitate tissue regeneration and repair.We here review how various aligned structures are fabricated,including aligned electrospun nanofibers,aligned porous or channeled structures,micropatterns and combinations thereof,and their application in nerve,skeletal muscle,tendon,and tubular dentin regeneration.The future use of aligned structures in tissue engineering is also discussed. | Kejie Lu Ying Qian Jiaxing Gong Ziyu Zhu Jun Yin Liang Ma Mengfei Yu Huiming Wang | 2021 | Bio-Design and Manufacturing2021，4，2： | 0 |
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