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| 1 | Role of sphingosine kinase and sphingosine-1-phosphate in inflammatory arthritis显示文摘The importance of sphingosine kinase(SphK)and sphingosine-1-phosphate(S1P)in inflammation has been extensively demonstrated.As an intracellular second messenger,S1P plays an important role in calcium signaling and mobilization,and cell proliferation and survival.Activation of various plasma membrane receptors,such as the formyl methionyl leucyl phenylalanine receptor,C5a receptor,and tumor necrosis factor α receptor,leads to a rapid increase in intracellular S1P level via SphK stimulation.SphK and S1P are implicated in various chronic autoimmune conditions such as rheumatoid arthritis, primary Sjgren's syndrome,and inflammatory bowel disease.Recent studies have demonstrated the important role of SphK and S1P in the development of arthritis by regulating the pro-inflammatory responses.These novel pathways represent exciting potential therapeutic targets. | Alirio J Melendez Bernard P Leung | 2010 | World Journal of Biological Chemistry2010，1，11： | 3 |
| 2 | Perioperative outcomes of major hepatic resections under low central venous pressure anesthesia: blood loss, blood transfusion, and the risk of postoperative renal dysfunction显示文摘 | Jose A Melendez Vittoria Arslan Mary E Fischer David Wuest William R Jarnagin Yuman Fong Leslie H Blumgart | 1998 | Journal of the American College of Surgeons1998，，6： | 2 |
| 3 | Photodynamic actions of indocyanine green and trypan blue on human lens epithelial cells in vitro显示文摘 | Melendez RF Kumar N Maswadi SM Zaslow K Glickmank RD | 2005 | Am J Ophthalmol2005，140，1： | 1 |
| 4 | Procalcitonin as a marker for the detection of bacteremia and sepsis in the emergency department 显示文摘 | Riedel S Melendez JH An AT | 2011 | Am J Clin Pathol2011，135，2： | 1 |
| 5 | Salmonella enterica isolates from pasture-raised poultry exhibit antimicrobial resistance and Class I integrons显示文摘 | Melendez S N Hanning I Han J | 2010 | Journal of Applied Microbiology2010，109，6： | 1 |
| 6 | Interleukin 6 mediates myocardial fibrosis,concentric hypertrophy,and diastolic dysfunction in rats显示文摘 | Melendez GC Mc Larty JL Levick SP | 2010 | Hypertension2010，56，2： | 1 |
| 7 | Advances in the emergency management of pediatric sepsis 显示文摘 | Melendez E Baehur R | 2006 | Curr Opin Pediatr2006，18，： | 1 |
| 8 | VCAM(CD-106) and ICAM(CD-54) Adhesion Molecules Distinguish Keratoacanthomas from Cutaneous Squamous Cell Carcinomas显示文摘 | Melendez ND Smoller BR Morgan M | 2003 | Mod Pathol2003，16，1： | 1 |
| 9 | Procalcitonin as a marker for the detection of bacteremia and sepsis in the emergency department显示文摘 | Riedel S Melendez JH An AT | 2011 | Am J Clin Pathol2011，135，2： | 1 |
| 10 | Preparation of Spherical MCM-41 Molecular Sieve at Room Temperature:Influence of the Synthesis Conditions in the Structural Properties显示文摘 | Melendez H I Garcia L A Olivares Y | 2012 | Ceramics International2012，38，8： | 1 |
| 11 | Immunosuppression withdrawal after auxiliary liver transplantation for acute liver failure显示文摘 | Girlanda R Vilca - Melendez H Srinivasan P | 2005 | Transplant Proc2005，37，4： | 1 |
| 12 | Short interfering RNA (siRNA) as a novel therapeutic显示文摘 | Pushparaj PN Melendez AJ | 2006 | Clin Exp Pharmacol Physiol2006，33，56： | 1 |
| 13 | Timing hypothesis for postmenopausal hormone therapy:its origin,current status,and future 显示文摘 | Clarkson TB Melendez GC Appt SE | 2013 | Menopause2013，20，3： | 1 |
| 14 | Hybrid approach for the assessment of PSA models by means of binary decision diagrams 显示文摘 | Cristina Ibanez-Llano Antoine Rauzy Enrique Melendez | 2010 | Reliability Engineering & System Safety2010，95，10： | 1 |
| 15 | Incidence of subclinical ketosis in cows supplemented with a monensin controlled-release capsule in Holstein cattle, Florida, USA 显示文摘 | Melendez P Goff J P Risco C A | 2006 | Preventive Veterinary Medicine2006，73，1： | 1 |
| 16 | Activation of the inflammasome and enhanced migration of micropartiele-stimulated dendritic cells to the draining lymph node 显示文摘 | Meraz IM Melendez B Gu JH | 2012 | Mol Pharmaceut2012，9，7： | 1 |
| 17 | A reduction approach to improve the quantification of linked fault trees through binary decision diagram 显示文摘 | Cristina Ibanez-Llano Antoine Rauzy Enrique Melendez | 2010 | Reliability Engineering & System Safety2010，95，12： | 1 |
| 18 | Conversion to re- sectability using hepatic artery infusion plus systemic chemo- therapy for the treatment of unresectable liver metastases from colorectal carcinoma显示文摘 | Kemeny NE Melendez FD Capanu M | 2009 | J Clin Oncol2009，27，21： | 1 |
| 19 | Effects of diquat on freshwater microbial communities 显示文摘 | MELENDEZ A L | 1993 | Arch Environ Contam Toxicol1993，25，： | 1 |
| 20 | 显示文摘 | Al-Haijri M Melendez A Woods R | 1999 | Journal of Alloys and Compounds1999，290，： | 1 |
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