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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | Cement leakage into the posterior spinal canal during balloon kyphoplasty:a case report显示文摘 | Becker S Meissner J Tuschel A | 2007 | J Orthopaed Surg2007，15，： | 1 |
| 3 | Isolation and charactefisation of a diverse family of Arabidopsis two and three-fingered C2H2 zinc finger protein genes and cDNAs显示文摘 | MEISSNER R MICHAEL A J | 1997 | Plant Mol Bio1997，33，4： | 1 |
| 4 | A new elongational rheometer for polymer melts and other viscoelastic liquids显示文摘 | MEISSNER J and HOSETTLER J | 1994 | J Rheol Acta1994，33，： | 1 |
| 5 | Tumor necrosis factor-al- pha-mediated downregnlation of the cystic fibrosis transmembrane conductance regulator drives pathological sphingosine-l-phosphate signaling in a mouse model of heart failure显示文摘 | Meissner A Yang J Kroetsch JT | 2012 | Circulation2012，125，22： | 1 |
| 6 | Effects of 3 - week oral treatment with the antioxidant thioctic acid (alpha - lipoic acid) in symptomatic diabetic polyneuropathy 显示文摘 | Ruhnau K J Meissner H P Firm J R | 1999 | Diabet Med1999，16，12： | 1 |
| 7 | Synthesis and surface activity of surfactants containing fluorocarbon hydrophobes 显示文摘 | Meissner E Myszkowki J Szymanowski J | 1995 | Tenside Surf Det1995，32，3： | 1 |
| 8 | Dynamic pricing strategies for multi-product revenue management problems显示文摘 | Maglaras C Meissner J | 2006 | Manufacturing and Service Oper Mgmnt2006，8，： | 1 |
| 9 | Effects of sheep exclusion on the soil seed bank and annual vegetation in chenopod shrub lands of South Australia显示文摘 | Meissner R A Facelli J M | 1999 | Journal of Arid Environment1999，42，2： | 1 |
| 10 | Effect of sheep exclusion on the soil seed bank and annual vegetation in chenopod shrub lands of South Australia 显示文摘 | Meissner R A Facelli J M | 1999 | Journal of Arid Environment1999，42，2： | 1 |
| 11 | Childhood vaccination against chickenpox: an analysis of benefits and costs 显示文摘 | Huse D M Meissner H C Lacey M J | 1994 | J Pediatr1994，124，6： | 1 |
| 12 | The major function of a metallothionein from the aquatic fungus Heliscus lugdunensis is cadmium detoxification显示文摘 | Loebus J Leitenmaier B Meissner D | 2013 | J Inorg Biochem2013，127，： | 1 |
| 13 | Reliability of the Modified Tardieu Scale and the Modified Ashworth Scale in adult patients with severe brain injury: a comparison study显示文摘 | Mehrholz J Wagner K Meissner D | 2005 | Clin Rehabil(S0269 - 2155)2005，19，： | 1 |
| 14 | Human papillomavirus prevalence in women with normal cytology and with cervical cancer in Natal显示文摘 | Fernandes J V Meissner R de V Carvalho M G | 2011 | Brazil Mol Med Rep2011，4，6： | 1 |
| 15 | Early thrombus removal strategies for acute deep venous thrombo- sis; clinical practice guidelines of the Society for Vascular Surgery and 'the American Venous Forum 显示文摘 | Meissner M H Gloviczki P Comerota A J | 2012 | Journal ofvascular surgery2012，55，5： | 1 |
| 16 | Varicella prevention in the United States:a review of successes and challenges显示文摘 | MARIN M MEISSNER H C SEWARD J F | 2008 | Pediatrics2008，122，3： | 1 |
| 17 | Catheter-directed thrombolysis in the treatment of phlegmasia cerulean dolens 显示文摘 | Patel NH Plorde J J Meissner M | 1995 | Ann Vasc Surg1995，12，5： | 1 |
| 18 | Effects of sheep exclusion on the soil seed bank and annual vegetation in chenopod shrublands of South Australia显示文摘 | Meissner R A Facelli J M | 1999 | Journal of Arid Environments1999，42，： | 1 |
| 19 | Effects of high glucose onmesenchymalstem cell proliferation and differentiation 显示文摘 | Li YM Schilling T Benisch P Zeck S Meissner -Weigl J Schneider D | 2007 | Biochem Bio-phys Res Commun2007，363，： | 1 |
| 20 | Tensile stress over shoot in uniaxial extension of a LDPE melt显示文摘 | WAGNER M H RAIBLE T MEISSNER J | 1979 | Rheol Acta1979，18，： | 1 |
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