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您的检索式：作者名="Meifeng FU"
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| 1 | Reciprocal interaction between vascular niche and sweat gland promotes sweat gland regeneration显示文摘The incorporation of vasculature is known to be effective in tissue or organ functional regeneration.However,a vague understanding of the interaction between epidermal appendages and their vascular niches is a foremost obstacle to obtaining sweat gland(SG)-specific vasculature units.Here,we map their precise anatomical con-nections and report that the interplay between SG cells(SGCs)and the surrounding vascular niche is key for glandular development and homeostasis maintenance.To replicate this interplay in vitro,we used three-dimensional(3D)bioprinting to generate reproducible SGC spheroids from differentiated adipose-derived mesenchymal stem cells(ADSCs).With dermal microvascular endothelial cells(DMECs),sacrificial templates made from poly(ε-caprolactone)(PCL)were fabricated to pattern the vascular niche.This interplay model promoted physiologically relevant vascularized glandular morphogenesis in vitro and in vivo.We identified a reciprocal regulatory mechanism for promoting SGs regeneration via contact-independent cell communication and direct cell-cell interactions between SGs and the vasculature.We envision the successful use of our approach for vascularized organ regeneration in the near future. | Xingyu Yuan Xianlan Duan Enhejirigala Zhao Li Bin Yao Wei Song Yuzhen Wang Yi Kong Shijun Zhu Fanliang Zhang Liting Liang Mengde Zhang Chao Zhang Deling Kong Meifeng Zhu Sha Huang Xiaobing Fu | 2023 | Bioactive Materials2023，，3： | 0 |
| 2 | Analysis on the Expression of TaMOR Gene in Two Different Spring Wheat Varieties at Different Years显示文摘[Objectives]The TaMOR gene is a gene that affects the initiation and growth of the secondary roots of wheat,but the expression patterns in different parts of the wheat root system and the differences in expression in different varieties are not clear.This study aimed to investigate the expression of the TaMOR gene in the seminal roots,secondary roots and root base.[Methods]Real-time fluorescence quantitative PCR technology was used to analyze the relative expression levels of the TaMOR gene in seminal roots,secondary roots and root base of seedlings of ancient variety Monkhead and modern variety Longchun 35.[Results]There was no significant difference in the number of seminal roots between Longchun 35 and Monkhead,and the numbers of seminal roots of the two varieties did not change significantly during the three sampling periods.The number of secondary roots and shoot dry weight of Longchun 35 were significantly higher than those of Monkhead,and the number of secondary roots and shoot dry weight of both varieties increased with the sampling time point.The root dry weight of Monkhead increased with the sampling time,while Longchun 35 showed the largest value at the second time.The fluorescence quantitative PCR results showed that for 13-day seedlings,the relative expression of the TaMOR gene in root base was significantly higher than that in the seminal roots and secondary roots.There was no significant difference in the relative expression of gene TaMOR in the root system of Monkhead and Longchun 35.[Conclusions]The root allocation of gramineous crops decreases with the breeding years,and the difference in gene TaMOR expression level needs further study. | Xia LI Qianglin WANG Chaoran LI Huafang ZHU Beixi ZHU Xin LIU Meifeng FU Lijun ZHU Li ZHU | 2020 | Agricultural Biotechnology2020，9，4： | 0 |
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