|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂的使用与2019冠状病毒疾病检测阳性之间的关系显示文摘血管紧张素转换酶抑制剂(angiotensin-converting enzyme inhibitor,ACEI)和血管紧张素受体拮抗剂(angiotensin receptor blocker,ARB)在2019新型冠状病毒疾病(coronavirus disease 2019,COVID-19)全球大流行背景下的作用备受争议。此类药物是治疗一些慢性病的必须药物,有建议停止使用这些药物. | Mehta N KalraA Nowacki AS Anjewierden S Han Z Bhat p Rubio AEC Jacob M Procop GW Harrington S Milinovich A Svensson LG Jehi L Young JB Chung MK 周卫(译) 叶鹏(校) | 2020 | 中华高血压杂志2020，28，5： | 9 |
| 2 | RTOG 0211:a phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients显示文摘PURPOSE: To determine the safety and efficacy of gefitinib,an epidermal growth factor receptor(EGFR) tyrosine kinase inhibitor,in combination with radiation for newly diagnosed glioblastoma(GBM) patients.METHODS AND MATERIALS: Between March 21,2002,and May 3,2004,Radiation Therapy Oncology Group(RTOG) 0211 enrolled 31 and 147GBM patients in the phase 1 and 2 arms,respectively.Treatment consisted of daily oral gefinitnib started at the time of conventional cranial radiation therapy(RT) and continued post RT for 18 months or until progression.Tissue microarrays from 68 cases were analyzed for EGFR expression.RESULTS: The maximum tolerated dose(MTD) of gefitinib was determined to be 500 mg in patients on non-enzyme-inducing anticonvulsant drugs(non-EIAEDs).All patients in the phase 2 component were treated at a gefitinib dose of 500 mg;patients receiving EIADSs could be escalated to 750 mg.The most common side effects of gefitinib in combination with radiation were dermatologic and gastrointestinal.Median survival was 11.5 months for patients treated per protocol.There was no overall survival benefit for patients treated with gefitinib + RT when compared with a historical cohort of patients treated with RT alone,matched by RTOG recursive partitioning analysis(RPA) class distribution.Younger age was significantly associated with better outcome.Per protocol stratification,EGFR expression was not found to be of prognostic value for gefitinib + RT-treated patients.CONCLUSIONS: The addition of gefitinib to RT is well tolerated.Median survival of RTOG 0211 patients treated with RT with concurrent and adjuvant gefitinib was similar to that in a historical control cohort treated with radiation alone. | Chakravarti A Wang M Robins HI Lautenschlaeger T Curran WJ Brachman DG Schultz CJ Choucair A Dolled-Filhart M Christiansen J Gustavson M Molinaro A Mischel P Dicker AP Bredel M Mehta M | 2013 | 中国神经肿瘤杂志2013，11，1： | 8 |
| 3 | Improved thermodynamic parameters for prediction of structure hydrate equilibria 显示文摘 | MEHTA A P SLOAN E D | 1996 | AICHE J1996，42，7： | 1 |
| 4 | Medullary thyroid cancer: early detection and novel treatments显示文摘 | Roman S Mehta P Sosa J A | 2009 | Curr Opin Oncol2009，21，1： | 1 |
| 5 | Excitotoxicity: bridge tovarious triggers in neurodegenerative disorders 显示文摘 | Mehta A Prabhakar M Kumar P | 2013 | Eur JPharmacol2013，698，13： | 1 |
| 6 | Pheno: typic characterization and identification of effector cells involved in tunor cell recognition of cytokine induced kil- ler cells显示文摘 | Schmidt-Wolf I G Lefterova P Mehta B A | 1993 | Exp Hematol1993，21，13： | 1 |
| 7 | Increeased serum neopterin leveels in adults with Donm syndrome 显示文摘 | Mehta P D Patarick B A Dalton A J | 2005 | J Neuroimmunol2005，164，2： | 1 |
| 8 | The social endocrinology of dominance: Basal testosterone predicts cortisol changes and behavior following victory and defeat显示文摘 | MEHTA P H JONES A C JOSEPHS R A | 2008 | Journal of Personality & Social Psychology2008，，94： | 1 |
| 9 | 查看详情显示文摘 | Haynam C A Wegner P J Auerbach J M Bowers M W Dixit S N Erbert G V Heestand G M Henesian M A Hermann M R Jancaitis K S Manes K R Marshall C D Mehta N C Menapace J Moses E Murray J R Nostrand M C Orth C D Patterson R SacksR A Shaw M J Spaeth M Sutton S B W | | 0，，： | 1 |
| 10 | A randomized, controlled study of a mandibular advancement splint for obstructive sleep apnea 显示文摘 | Mehta A Qian J Petocz P | 2001 | Am J Respir Crit Care Med2001，163，6： | 1 |
| 11 | Effect of compressed CO2 on crystallization and melting behavior of isotactic polyproplene显示文摘 | Varma-Nair M Handa P Y Mehta A K | 2003 | ThermochimicaActa2003，396，： | 1 |
| 12 | Molecular mechanisms of apoptosis in cerebral ischemia: multiple neuroprotective opportunities显示文摘 | Nakka V P Gusain A Mehta S L | 2008 | Mol Neurobiol2008，37，1： | 1 |
| 13 | Quantification of sub-femtomole amounts of Alzheimer amyloid beta peptides显示文摘 | Potempska A Mack K Mehta P | 1999 | Amyloid1999，6，1： | 1 |
| 14 | Behavior problems in nephrotie syndrome 显示文摘 | MEHTA M BAGGA A PANDE P | 1995 | Indian Pediatr1995，32，12： | 1 |
| 15 | Airway stents显示文摘 | Lee P Kupeli E Mehta A C | 2010 | Clin Chest Med2010，31，1： | 1 |
| 16 | Mucosal expression of cyclooxygenase isoforms 1 and 2 is increased with worsening damage to the gastric mucosa显示文摘 | A C Bateman R L Mehta | 2005 | Histopathology2005，46，3： | 1 |
| 17 | Development of a feature recognition module for tapered and curved base featores显示文摘 | Arivazhagan A Mehta N K Jain P K | 2008 | Int J Adv Manuf Technol2008，39，： | 1 |
| 18 | Strategies for handling UPFC constraints in steady-state power flow and voltage control显示文摘 | Jun-Yong Liu Yong-Hua Song Mehta P A | 2000 | IEEE Trans on Power Systems2000，15，2： | 1 |
| 19 | Behavior problems in nephrotic syndrome 显示文摘 | Mehta M Bagga A Pande P | 1995 | Indian Pediatr1995，32，12： | 1 |
| 20 | Phenotypic char- acterization and identification of effector ceils involved in tumor cell recognition of cytokine-induced killer cells显示文摘 | Schmidt-Wolf I G Lefterova P Mehta B A | 1993 | Exp Hematol1993，21，13： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员