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| 1 | 血压变异性预测自发性脑出血患者的院内不良预后显示文摘越来越多的证据表明,较高的收缩压变异性(systolicblood pressure variability ,SBPV)可能与脑出血患者的不良预后相关。该研究探讨了 SB PV 与院内脑出血预后之间的关系。研究者在2个医疗系统中收集了10年的自发性脑出血患者的连续数据。记录人口统计学、病史、实验室测试、计算机断层扫描数据、院内治疗情况以及神经和功能评估。在入院后24h内获取血压记录。 | 刘青 叶鹏 Divani AA Liu X Di Napoli M Lattanzi S Ziai W James ML Jafarli A Jafari M Saver JL Hemphill JC Vespa PM Mayer SA Petersen A | 2019 | 中华高血压杂志2019，27，8： | 6 |
| 2 | Combination drug regimens for metastatic clear cell renal cell carcinoma显示文摘Renal cell carcinomas(RCC)make up about 90%of kidney cancers,of which 80%are of the clear cell subtype.About 20%of patients are already metastatic at the time of diagnosis.Initial treatment is often cytoreductive nephrectomy,but systemic therapy is required for advanced RCC.Single agent targeted therapies are moderately toxic and only somewhat effective,leading to development of immunotherapies and combination therapies.This review identifies limitations of monotherapies for metastatic renal cell carcinoma,discusses recent advances in combination therapies,and highlights therapeutic options under development.The goal behind combining various modalities of systemic therapy is to potentiate a synergistic antitumor effect.However,combining targeted therapies may cause increased toxicity.The initial attempts to create therapeutic combinations based on inhibition of the vascular endothelial growth factor or mammalian target of rapamycin pathways were largely unsuccessful in achieving a profile of increased synergy without increased toxicity.To date,five combination therapies have been approved by the U.S.Food and Drug Administration,with the most recently approved therapies being a combination of checkpoint inhibition plus targeted therapy.Several other combination therapies are under development,including some in the phase 3 stage.The new wave of combination therapies for metastatic RCC has the potential to increase response rates and improve survival outcomes while maintaining tolerable side effect profiles. | Viraj V Khetani Daniella E Portal Mansi R Shah Tina Mayer Eric A Singer | 2020 | World Journal of Clinical Oncology2020，11，8： | 2 |
| 3 | Gut/brain axis and the microbiota显示文摘 | Mayer Emeran A Tillisch Kirsten Gupta Arpana | 2015 | Journal of Clinical Investigation2015，，3： | 2 |
| 4 | Infrared thermal sensing of plant canopies as a screening technique for dehydration a-voidance in wheat显示文摘 | Blum A Mayer J Gozlan G | 1982 | Field Crops Research1982，5，： | 1 |
| 5 | Coutinho SV1 stress and the gastrointestinal tract V1 stress and irrirable bowel syndromel 显示文摘 | Mayer E A Naliboff B D Chang L | 2001 | Am J Physiol Gastrointest Liver Physiol2001，280，4： | 1 |
| 6 | Perilesional blood flow and edema formation in acute intracerebral hemorrhage:a SPECT study显示文摘 | Mayer SA Lignelli A Fink ME | 1998 | Stroke1998，29，9： | 1 |
| 7 | Perilesional blood flow and edema formation in acute intracerebral hemorrhage: a SPECT study 显示文摘 | Mayer S A Lignelli A Fink M E | 1998 | Stroke1998，29，9： | 1 |
| 8 | Perilesional blood flow and edema formation in acute intracerebral hemorrhage:a SPECT study显示文摘 | Mayer SA Lignelli A Fink ME | 1998 | Stroke1998，29，9： | 1 |
| 9 | Efficient screening of process variables 显示文摘 | STOWE R A MAYER R P | 1966 | Industrial and Engineering Chemistry1966，58，2： | 1 |
| 10 | Fluorouracil and highdose leuco -vorin in previously untreated patients with advanced adenocarcinoma of the pancreas : re - suits of a phase * trial显示文摘 | DECAPRIO J A MAYER R J GONIN R | 1991 | J Clin Oncol1991，9，12： | 1 |
| 11 | The morphology of silicon carbide in C/C-SiC composites显示文摘 | Schulte-Fischedick J Zem A Mayer J | 2002 | Mater Sci Eng A2002，332，12： | 1 |
| 12 | Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis显示文摘 | Mayer E A Berman S Suyenobu B | 2005 | Pain2005，115，3： | 1 |
| 13 | The morphology of silicon carbide in C/C-SiC composites显示文摘 | Schulte-Fischedick J Zern A Mayer J | 2002 | Mater Sci Eng2002，332，： | 1 |
| 14 | Trearment of intracerebral haemohage 显示文摘 | Mayer S A Rineon F | 2005 | Laneet Neurol2005，4，10： | 1 |
| 15 | The morphology of silicon carbide in C/C-SiC composites显示文摘 | SCHULTE F J ZERN A MAYER J | 2002 | Materials Science and Engineering:A2002，332，12： | 1 |
| 16 | Attenuation of classical swine fever virus by deletion of the viral N(pro) gene 显示文摘 | Mayer D Hofmann M A Tratschin J D | 2004 | Vaccine2004，22，34： | 1 |
| 17 | Perilesional blood flow and ede-ma formation in acute intracerebral hemorrhage:a spect study显示文摘 | L1j Mayer SA lignelli A Fink ME | 1998 | Stroke1998，29，9： | 1 |
| 18 | Influence of Al2O3 nano-dispersionson microstructure features and mechanical properties of cast and T6 heat-treated Al-Si hypoeutectic Alloys显示文摘 | I El-Mahallawi H Abdelkader L Yousef A Amer J Mayer A Schwedt | 2012 | Materials Science&Engineering A2012，556，： | 1 |
| 19 | Assessment of intake from the diet显示文摘 | R Kroes D Müller J Lambe M.R.H L?wik J van Klaveren J Kleiner R Massey S Mayer I Urieta P Verger A Visconti | 2002 | Food and Chemical Toxicology2002，，2： | 1 |
| 20 | Calcium-sensing receptor autoantibodies are relevant markers of acquiredhypoparathyroidism 显示文摘 | Mayer A Ploix C Orgiazzi J | 2004 | J Clin Endocrinol Metab2004，89，： | 1 |
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