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| 1 | Biodegradation of polycyclic aromatic hydrocarbons(PAHs)by fungal enzymes:A review显示文摘Polycyclic aromatic hydrocarbons(PAHs) are a large group of chemicals.They represent an important concern due to their widespread distribution in the environment,their resistance to biodegradation,their potential to bioaccumulate and their harmful effects.Several pilot treatments have been implemented to prevent economic consequences and deterioration of soil and water quality.As a promising option,fungal enzymes are regarded as a powerful choice for degradation of PAHs.Phanerochaete chrysosporium,Pleurotus ostreatus and Bjerkandera adusta are most commonly used for the degradation of such compounds due to their production of ligninolytic enzymes such as lignin peroxidase,manganese peroxidase and laccase.The rate of biodegradation depends on many culture conditions,such as temperature,oxygen,accessibility of nutrients and agitated or shallow culture.Moreover,the addition of biosurfactants can strongly modify the enzyme activity.The removal of PAHs is dependent on the ionization potential.The study of the kinetics is not completely comprehended,and it becomes more challenging when fungi are applied for bioremediation.Degradation studies in soil are much more complicated than liquid cultures because of the heterogeneity of soil,thus,many factors should be considered when studying soil bioremediation,such as desorption and bioavailability of PAHs.Different degradation pathways can be suggested.The peroxidases are heme-containing enzymes having common catalytic cycles.One molecule of hydrogen peroxide oxidizes the resting enzyme withdrawing two electrons.Subsequently,the peroxidase is reduced back in two steps of one electron oxidation.Laccases are copper-containing oxidases.They reduce molecular oxygen to water and oxidize phenolic compounds. | Tayssir Kadri Tarek Rouissi Satinder Kaur Brar Maximiliano Cledon Saurabhjyoti Sarma Mausam Verma | 2017 | Journal of Environmental Sciences2017，29，1： | 19 |
| 2 | Radiofrequency ablation vs surgical resection in elderly patients with hepatocellular carcinoma in Milan criteria显示文摘BACKGROUND Surgical resection and radiofrequency ablation(RFA)represent two possible strategy in treatment of hepatocellular carcinoma(HCC)in Milan criteria.AIM To evaluate short-and long-term outcome in elderly patients(>70 years)with HCC in Milan criteria,which underwent liver resection(LR)or RFA.METHODS The study included 594 patients with HCC in Milan criteria(429 in LR group and 165 in RFA group)managed in 10 European centers.Statistical analysis was performed using the Kaplan-Meier method before and after propensity score matching(PSM)and Cox regression.RESULTS After PSM,we compared 136 patients in the LR group with 136 patients in the RFA group.Overall survival at 1,3,and 5 years was 91%,80%,and 76%in the LR group and 97%,67%,and 41%in the RFA group respectively(P=0.001).Diseasefree survival at 1,3,and 5 years was 84%,60%and 44%for the LR group,and 63%,36%,and 25%for the RFA group(P=0.001).Postoperative Clavien-Dindo IIIIV complications were lower in the RFA group(1%vs 11%,P=0.001)in association with a shorter length of stay(2 d vs 7 d,P=0.001).In multivariate analysis,Model for End-stage Liver Disease(MELD)score(>10)[odds ratio(OR)=1.89],increased value of international normalized ratio(>1.3)(OR=1.60),treatment with radiofrequency(OR=1.46),and multiple nodules(OR=1.19)were independent predictors of a poor overall survival while a high MELD score(>10)(OR=1.51)and radiofrequency(OR=1.37)were independent factors associated with a higher recurrence rate.CONCLUSION Despite a longer length of stay and a higher rate of severe postoperative complications,surgery provided better results in long-term oncological outcomes as compared to ablation in elderly patients(>70 years)with HCC in Milan criteria. | Maria Conticchio Riccardo Inchingolo Antonella Delvecchio Letizia Laera Francesca Ratti Maximiliano Gelli Ferdinando Anelli Alexis Laurent Giulio Vitali Paolo Magistri Giacomo Assirati Emanuele Felli Taiga Wakabayashi Patrick Pessaux Tullio Piardi Fabrizio di Benedetto Nicola de'Angelis Javier Briceño AntonioRampoldi RenèAdam Daniel Cherqui Luca Antonio Aldrighetti Riccardo Memeo | 2021 | World Journal of Gastroenterology2021，27，18： | 4 |
| 3 | Potential Use of a Poultry Manure Digestate as a Biofertiliser:Evaluation of Soil Properties and Lactuca sativa Growth显示文摘Anaerobic digestion is a process that is widely used for the treatment of organic wastes. The digestate can be used as a soil amendment or crop fertiliser. The aims of our work were to evaluate 1) the physicochemical composition and pathogen content in a digestate from poultry manure, according to international regulations, and 2) the effect of its soil application on the major chemical and biological soil properties and on the growth of Lactuca sativa. The experiment consisted of two groups of pots(with and without crop). Treatments applied to each group were as follows: low and high doses of digestate and inorganic fertiliser, and no application(control)(low dose: 70 kg nitrogen(N) ha^(-1) and 21 kg phosphorus(P) ha^(-1); high dose: 210 kg N ha^(-1) and 63 kg P ha^(-1)). Soil samples were taken 7 and 34 d(harvest) after treatment applications. Heavy metal and pathogen contents in the digestate were below the upper limit values. Despite the high pH and electrical conductivity values of the digestate, both soil parameters presented acceptable values for crop growth. Although there were no initial increases in total inorganic N and available P in soil with digestate application, an increase in the fresh weight of crop was observed with the high dose application. This is probably associated with the slow nutrient release from the digestate during the development of the crop. Changes in the microbial community were temporary and occurred at the initial sampling stage of the experiment. | Natalia MóRTOLA Romina ROMANIUK Vanina COSENTINO Maximiliano EIZA Patricia CARFAGNO Pedro RIZZO Patricia BRES Nicolás RIERA Marcos ROBA Mariano BUTTI Daiana SAINZ Lucrecia BRUTTI | 2019 | Pedosphere2019，29，1： | 2 |
| 4 | Antihypertensive and vasorelaxant effects of tilianin isolated from Agastache mexicana are mediated by NO/cGMP pathway and potassium channel opening显示文摘 | Oswaldo Hernández-Abreu Patricia Castillo-Espa?a Ismael León-Rivera Maximiliano Ibarra-Barajas Rafael Villalobos-Molina Judith González-Christen Jorge Vergara-Galicia Samuel Estrada-Soto | 2009 | Biochemical Pharmacology2009，，1： | 2 |
| 5 | Monolithic LC method applied to fesoterodine fumarate low dose extended-release tablets:Dissolution and release kinetics显示文摘A dissolution test for fesoterodine low dose extended-release tablets using liquid chromatographic(LC) method equipped with a C18 monolithic column was developed and validated. LC system was operated isocratically at controlled temperature(40 1C) using a mobile phase of acetonitrile:methanol:0.03 M ammonium acetate(p H 3.8)(30:15:55, v/v/v), run at a flow rate of 1.5 m L/min and detected at 208 nm. The best dissolution conditions for this formulation were achieved using a USP apparatus 2(paddle) at 100 rpm and 900 m L of phosphate buffer at p H 6.8 as the dissolution medium.Validation parameters such as the specificity, linearity, accuracy, precision, and robustness were evaluated according to international guidelines, giving results within the acceptable range. The kinetic parameters of drug release were also investigated using model-dependent methods and the dissolution profiles were best described by the Higuchi model. The validated dissolution test can be applied for quality control of this formulation. | Maximiliano S.Sangoi Vítor Todeschini Martin Steppe | 2015 | Journal of Pharmaceutical Analysis2015，5，2： | 2 |
| 6 | Study of canine parvovirus evolution: comparative analysis of full-length VP2 gene sequences from Argentina and international field strains 显示文摘 | Marina G C Maximiliano W Lorena B | 2012 | Virus Genes2012，44，： | 1 |
| 7 | Effect of humic acids on the adsorption of paraquat by goethite显示文摘 | Brigante Maximiliano Zanini Graciela Avena Marcelo | 2010 | Journal of Hazardous Materials2010，184，13： | 1 |
| 8 | High-frequency digital lock-in amplifier using random sampling 显示文摘 | SONNAILLON Maximiliano O URTEAGA Raul BONETTO Fabian J | 2008 | IEEE Transactions on Instrumentation and Measurement2008，57，3： | 1 |
| 9 | Macromolecular coupling agents for flame retardant materials显示文摘 | Sonia Marli Bohrz Nachtigall Maximiliano Miotto Elisangeta Edila Schneider | 2006 | European Polymer Journal2006，42，： | 1 |
| 10 | A seismic vulnerability index for confined masonry shear wall buildings and a relationship with the damage 显示文摘 | Kenneth A Gent Franch Gian M Giuliano Morbelli Maximiliano A Astroza Inostroza | 2008 | Engineering Structures2008，30，10： | 1 |
| 11 | Coxiella burnetii locali- zes in a RabT-labeled compartment with autophagic characteristics 显示文摘 | Beron W Maximiliano G Gutierrez | 2002 | Infect Immun2002，70，10： | 1 |
| 12 | A Randomized Phase 3 Trial Comparing Pemetrexed/Carboplatin and Docetaxel/Carboplatin as First-Line Treatment for Advanced, Nonsquamous Non-small Cell Lung Cancer显示文摘 | José Rodrigues-Pereira Joo-Hang Kim Manuel Magallanes Dae Ho Lee Jie Wang Vinod Ganju Luis Martínez-Barrera Helen Barraclough Maximiliano van Kooten Mauro Orlando | 2011 | Journal of Thoracic Oncology2011，，： | 1 |
| 13 | Summer PrecipitationEvents over the Western Slope of the Subtropical Andes 显示文摘 | Maximiliano Viale and Rene Garreaud | 2014 | MonthlyWeather Review2014，142，： | 1 |
| 14 | Macro- molecular coupling agents for flame retardant materials显示文摘 | Sonia M B N Maximiliano M Elisangela E S | 2006 | European polymer2006，42，5： | 1 |
| 15 | Systemic scleroderma with moderate to severe mitral regurgitation: Unusual three-dimensional echocardiographic features显示文摘 | Rami N. Khouzam Ivan A. D’Cruz Maximiliano Arroyo Daniel Minderman | 2008 | Canadian Journal of Cardiology2008，，2： | 1 |
| 16 | A multicenter, U.S. experience of single-balloon, double-balloon, and rotational overtube–assisted enteroscopy ERCP in patients with surgically altered pancreaticobiliary anatomy (with video)显示文摘 | Raj J. Shah Maximiliano Smolkin Roy Yen Andrew Ross Richard A. Kozarek Douglas A. Howell Gennadiy Bakis Sreenivasan S. Jonnalagadda Abed A. Al-Lehibi Al Hardy Douglas R. Morgan Amrita Sethi Peter D. Stevens Paul A. Akerman Shyam J. Thakkar Brian C. Brauer | 2013 | Gastrointestinal Endoscopy2013，，4： | 1 |
| 17 | Laparoscopic Colectomy: Medial Versus Lateral Approach显示文摘 | Nicolas A. Rotholtz Maximiliano E. Bun Margarita Tessio Sandra M. Lencinas Mariano Laporte Maria L. Aued Carlos E. Peczan Norberto A. Mezzadri | 2009 | Surgical Laparoscopy Endoscopy & Percutaneous Techniques2009，，1： | 1 |
| 18 | Metals in Alcoholic Beverages: A Review of Sources, Effects, Concentrations, Removal, Speciation, and Analysis 显示文摘 | JORGE G I ALEJANDRA C A MAXIMILIANO B S | 2008 | Journal of Food Composition and?Analysis2008，21，8： | 1 |
| 19 | Lock-in amplifier error prediction and correction in frequency sweep measurements显示文摘 | Maximiliano O S and Fabian J B | 2007 | Review of Scientific Instruments2007，78，1： | 1 |
| 20 | Steam reforming of sunflower oil for hydrogen production显示文摘 | Maximiliano Marquevich Roberto Coll Daniel Montaneé | 2000 | Industrial & Engineering Chemisty Research2000，39，： | 1 |
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