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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Towards curative therapy in gastric cancer:Faraway, so close!显示文摘Although recent diagnostic and therapeutic advances have substantially improved the survival of patients with gastric cancer(GC), the overall prognosis is still poor. Surgery is the only curative treatment and should be performed in experienced centers. Due to high relapse following surgery, complementary and systemic treatment aimed at eradicating micrometastasis should be performed in most cases. Cytotoxic treatments are effective in downstaging locally advanced cancer, but different sensitivities and toxicities probably exist in different GC subtypes. Current treatment protocols are based primarily on clinical data and histological features, but molecular biomarkers that would allow for the prediction of treatment responses are urgently needed. Understanding how host factors are responsible for inter-individual variability of drug response or toxicity will also contribute to the development of more effective and less toxic treatments. | Marília Cravo Catarina Fidalgo Rita Garrido Tania Rodrigues Gon?alo Luz Carolina Palmela Marta Santos Fábio Lopes Rui Maio | 2015 | World Journal of Gastroenterology2015，21，41： | 2 |
| 3 | Determination of water-soluble hexavalent chromium in clinker samples bywavelength-dispersive x-ray fluorescence spectrometry after concentration in activated layers显示文摘 | Eva M Claudia F S Marta T | 2010 | Applied Spectroscopy2010，64，： | 1 |
| 4 | Color Doppler imaging of fibroadenomas of the breast with histophathologie correlation显示文摘 | Selwyn S T Orith F R Marta M O | 2004 | J Clin Ultrasound2004，32，2： | 1 |
| 5 | FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis显示文摘 | Rossella Menghini Viviana Casagrande Marina Cardellini Marta Ballanti Francesca Davato Iris Cardolini Robert Stoehr Marta Fabrizi Monica Morelli Lucia Anemona Isabel Bernges Edzard Schwedhelm Arnaldo Ippoliti Alessandro Mauriello Rainer H. B?ger Massimo F | 2015 | Atherosclerosis2015，，： | 1 |
| 6 | Consequence a- nalysis by means of characteristic curves to determine the damage to humans from the detonation of explosive substances as a function of TNT equivalence显示文摘 | Fernando D A Enrique G F Marta D M | 2008 | Journal of Loss Prevention in the Process Industries2008，20，1： | 1 |
| 7 | Assisted Reproductive Technologies Are Associated With Cardiovascular Remodeling In Utero That Persists Postnatally显示文摘 | Brenda Valenzuela-Alcaraz Fàtima Crispi Bart Bijnens Monica Cruz-Lemini Montserrat Creus Marta Sitges Joaquim Bartrons Salvadora Civico Juan Balasch Eduard Gratacós | 2013 | Circulation2013，，13： | 1 |
| 8 | The magnitude of copigmentation in the color of aged red wines made in the Canary Islands 显示文摘 | Jacinto D Marta C L Jose F | 2007 | Eur Food Res Technol2007，224，： | 1 |
| 9 | A matrix approach coupled with Monte Carlo techniques for solving the net radiative balance of the urban b!ock显示文摘 | MARTA J N O P HEIDER J P G PAUIO M C F | 2007 | Boundary-Layer Meteorology2007，122，1： | 1 |
| 10 | The role of rhizobacteria in rice plants: Growth and mitigation of toxicity显示文摘Allelopathic compounds reduce the growth and productivity of upland rice plants, especially in consecutive plantations. The rhizobacteria Pseudomonas fluorescens BRM-32111 and Burkholderia pyrrocinia BRM-32113 have been recorded as growth promoters in rice. This study was developed to understand the effect of the application of rhizobacteria on upland rice plants in consecutive plantations. Experiments were conducted in a completely randomized design with four replications of four treatments: rice seed inoculated with P. fluorescens BRM-32111, rice seed inoculated with B. pyrrocinia BRM-32113(both sown on soil with rice residue), non-inoculated plants sown on soil with rice residue(control with residue(WR)), and non-inoculated plants on soil with no residue(NR). Roots and seedling growth were adversely affected by allelopathic compounds in control WR plants. Plants inoculated with rhizobacteria P. fluorescens BRM-32111 or B. pyrrocinia BRM-32113 induced an increase of 88% in biomass, 3% in the leaf area, 40% in length, 67% in root biomass, 21% in chlorophyll a, 53% in chlorophyll(a+b), 50% in rate of carbon assimilation(A), 227% in A/rubisco carboxylation efficiency(C_i) and 63% in water use efficiency(WUE) compared to control WR plants. These results indicate that rhizobacteria P. fluorescens BRM-32111 and B. pyrrocinia BRM-32113 increase the tolerance of rice plants to stress from allelochemicals. There are possible practical agricultural applications of these results for mitigating the effects of environmental allelochemistry on upland rice. | Marcela C F Rêgo Aline F Cardoso Thayná da C Ferreira Marta C C de Filippi Telma F V Batista Rafael G Viana Gisele B da Silva | 2018 | Journal of Integrative Agriculture2018，17，12： | 1 |
| 11 | Effect of storage on chemical and sensory profiles of peanut pastes prepared with high-oleic and normal peanuts显示文摘 | Riveros Cecilia G Mestrallet Marta G Gayol Maria F | 2010 | Journal of the Science of Food and Agriculture2010，90，15： | 1 |
| 12 | Defects of the insulin receptor substrate (IRS) system in human metabolic disorders 显示文摘 | Giorgio S Massimo F Marta L | 2001 | FASEB J2001，15，10： | 1 |
| 13 | Knowledge spillovers in science and technology parks: How can firms benefit most? 显示文摘 | Isabel D V Marta F O | 2014 | The Journal of Technology Transfer2014，，1： | 1 |
| 14 | Structure of the hydroxyquinol 1, 2-dioxygenase from nocardioides simplex 3E, a key enzyme involved in polychlorinated aromatics bio- degradation 显示文摘 | Marta F Jana S Vasili M T | 2005 | Journal of Biological Chemistry2005，280，21： | 1 |
| 15 | Current methodology for detection,identification and quantification of genetically modified organisms显示文摘 | MARTA H DAVID R L ALEJANDRO F | 2005 | Current Analytical Chemistry2005，1，2： | 1 |
| 16 | A further study about the behaviour of foundation piles and beams in a Winkler- Pasternak soil 显示文摘 | CARLOS P F MARTA B R | 2002 | Int J Mech Sci2002，44，： | 1 |
| 17 | Species-dependent chromium accumulation,lipid peroxidation,and glutathione lev-els in germinating kiwifruit pollen under Cr(III)and Cr(VI)stress显示文摘 | Valeria S Marta L Maria F P | 2008 | Chemosphere2008，73，7： | 1 |
| 18 | A further study about the behaviour of foundation piles and beams in a Winkler-Pasternak soil显示文摘 | Carlos P F Marta B R | 2002 | Int J Mech Sci2002，44，1： | 1 |
| 19 | Loss of SPARC in bladder cancer enhances carcinogenesis and progression显示文摘 | Said Neveen Frierson Henry F Sanchez-Carbayo Marta Brekken Rolf A Theodorescu Dan | 2013 | Journal of Clinical Investigation2013，，： | 1 |
| 20 | Mitochondrial Dysfunction: A Basic Mechanism in Inflammation-Related Non-Communicable Diseases and Therapeutic Opportunities显示文摘 | Anna Hernández-Aguilera Anna Rull Esther Rodríguez-Gallego Marta Riera-Borrull Fedra Luciano-Mateo Jordi Camps Javier A. Menéndez Jorge Joven Fábio Santos Lira | 2013 | Mediators of Inflammation2013，，： | 1 |
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