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| 1 | Videothoracoscopic management of the solitary pulmonary nodule: a single-institution study on 429 cases显示文摘 | Giuseppe Cardillo Mohamed Regal Francesco Sera Marco Di Martino Luigi Carbone Francesco Facciolo Massimo Martelli | 2003 | The Annals of Thoracic Surgery2003，，5： | 2 |
| 2 | Design Considerations for an Underactuated Robotic Finger Mechanism显示文摘A design approach is presented in this paper for underactuation in robotic finger mechanisms. The characters of underactuated finger mechanisms are introduced as based on linkage and spring systems,The feature of self-adaptive enveloping grasp by underactuated finger mechanisms is discussed with feasible in grasping unknown objects. The design problem of robotic fingers is analyzed by looking at many aspects for an optimal functionality. Design problems and requirements for underactuated mechanisms are formulated as related to human-like robotic fingers. In particular,characteristics of finger mechanisms are analyzed and optimality criteria are summarized with the aim to formulate a general design algorithm. A general multi-objective optimization design approach is applied as based on a suitable optimization problem by using suitable expressions of optimality criteria. An example is illustrated as an improvement of finger mechanism in Laboratory of Robotics and Mechatronics (LARM) Hand. Results of design outputs and grasp simulations are reported with the aim to show the practical feasibility of the proposed concepts and computations. | YAO Shuangji CECCARELLI Marco ZHAN Qiang CARBONE Giuseppe LU Zhen | 2009 | Chinese Journal of Mechanical Engineering2009，22，4： | 2 |
| 3 | Left atrial thrombosis in an anticoagulated patient after bioprosthetic valve replacement:Report of a case显示文摘We present the case of a 74 year old woman suffering from severe mitral valve incompetence and rapid atrial fibrillation. After an appropriate vitamin K antagonist(VKA) therapy, the patient underwent mitral valve replacement by bioprosthesis. Then, the patient was rehospitalized for jaundice. Suspecting hepatotoxicity, VKA was discontinued and fondaparinux was started. During this treatment, the patient developed a symptomatic atrial thrombus. After exclusion of a hepatic disease, VKA was re-established with hemodynamic and liver enzymes normalization and atrial thrombus resolution. Caution has to be used when considering fondaparinux as an alternative strategy to VKA in patients with multiple thrombotic risk factors. | Gian Marco Rosa Antonello Parodi Ulrico Dorighi Federico Carbone Franois Mach Alessandra Quercioli Fabrizio Montecucco Nicolas Vuilleumier Manrico Balbi Claudio Brunelli | 2014 | World Journal of Clinical Cases2014，2，1： | 2 |
| 4 | Comprehensive review of autoantibodies in patients with hyper-IgM syndrome显示文摘Hyper-immunoglobulin M syndrome is an X-linked primary immunodeficiency disease caused by mutations in the CD40 ligand gene.The CD40 ligand has been recently highlighted as playing a key role in the pathogenesis of primary biliary cholangitis.In the present study,we assessed an extensive set of serum autoantibodies in a series of well-defined patients with hyper-immunoglobulin M syndrome.Serum,liver-related and liver-not-related autoantibodies IgG,IgM and IgA were tested by ELISA and standard indirect immunofluorescence in HEp-2 cells in 13 Tunisian patients(8 males and 5 females,aged 1–12 years)with hyper-immunoglobulin M syndrome during 1995–2012 and,as controls,21 age-and gender-matched blood donors.The level of IgM antibody against MIT3 was significantly higher in patients than in controls(35.8 vs 10.7,P=0.002).Half of the hyperimmunoglobulin M syndrome patients were found to be anti-MIT3 IgM positive vs none of the controls(Po0.0001).Twenty-three percent of patients were found to be anti-sp100 antibody positive vs only 0.05%of controls.By immunofluorescence,92.3%of patients were MIT3 IgM positive vs none of the controls.In conclusion,the IgM class of anti-MIT3 antibodies was shown to be present by both ELISA and immunofluorescence in most of the patients with hyper-immunoglobulin M syndrome.The presence of the hallmark of primary biliary cholangitis,a disease where the CD40 ligand is a key player,in an immunodeficiency disease caused by mutations in the CD40 ligand gene is very intriguing and opens new scenarios in understanding the immune pathogenesis of primary biliary cholangitis. | Mohamed-Ridha Barbouche Qubo Chen Marco Carbone Imen Ben-Mustapha Zakera Shums Mehdi Trifa Federica Malinverno Francesca Bernuzzi Haiyan Zhang Nourhen Agrebi Gary L Norman Christopher Chang M Eric Gershwin Pietro Invernizzi | 2018 | Cellular & Molecular Immunology2018，15，6： | 2 |
| 5 | Current controversies and future perspectives on treatment of intensive care unit delirium in adults显示文摘Delirium is the most frequent manifestation of acute brain dysfunction in intensive care unit(ICU).Although antipsychotics are widely used to treat this serious complication,recent evidence has emphasized that these agents did not reduce ICU delirium(ICU-D)prevalence and did not improve survival,length of ICU or hospital stay after its occurrence.Of note,no pharmacological strategy to prevent or treat delirium has been identified,so far.In this scenario,new scientific evidences are urgently needed.Investigations on specific ICU-D subgroups,or focused on different clinical settings,and studies on medications other than antipsychotics,such as dexmedetomidine or melatonin,may represent interesting fields of research.In the meantime,because there is some evidence that ICU-D can be effectively prevented,the literature suggests strengthening all the strategies aimed at prevention through no-pharmacological approaches mostly focused on the correction of risk factors.The more appropriate strategy useful to treat established delirium remains the use of antipsychotics managed by choosing the right doses after a careful case-by-case analysis.While the evidence regarding the use of dexmedetomidine is still conflicting and sparse,this drug offers interesting perspectives for both ICU-D prevention and treatment.This paper aims to provide an overview of current pharmacological approaches of evidence-based medicine practice.The state of the art of the on-going clinical research on the topic and perspectives for future research are also addressed. | Marco Cascella Marco Fiore Sebastiano Leone Domenico Carbone Raffaela Di Napoli | 2019 | World Journal of Critical Care Medicine2019，8，3： | 2 |
| 6 | Autoimmune liver disease, autoimmunity and liver transplantation显示文摘 | Marco Carbone James M. Neuberger | 2014 | Journal of Hepatology2014，，： | 2 |
| 7 | How regenerative medicine and tissue engineering may complement the available armamentarium in gastroenterology?显示文摘The increasing shortage of donors and the adverse effects of immunosuppression have restricted the impact of solid organ transplantation.Despite the initial promising developments in xenotransplantation,roadblocks still need to be overcome and this form of organ support remains a long way from clinical practice.While hepatocyte transplantation may be effectively correct metabolic defects,it is far less effective in restoring liver function than liver transplantation.Tissue engineering,using extracellular matrix scaffolds with an intact but decellularized vascular network that is repopulated with autologous or allogeneic stem cells and/or adult cells,holds great promise for the treatment of failure of organs within gastrointestinal tract,such as endstage liver disease,pancreatic insufficiency,bowel failure and type 1 diabetes.Particularly in the liver field,where there is a significant mortality of patients awaiting transplant,human bioengineering may offer a source of readily available organs for transplantation.The use of autologous cells will mitigate the need for long term immunosuppression thus removing a major hurdle in transplantation. | Marco Carbone Jan Lerut James Neuberger | 2012 | World Journal of Gastroenterology2012，18，47： | 2 |
| 8 | Prevention of hepatitis C recurrence after liver transplantation:An update显示文摘Hepatitis C related liver failure and hepatocarcinoma are the most common indications for liver transplantation in Western countries.Recurrent hepatitis C infection of the allograft is universal and immediate following liver transplantation,being associated with accelerated progression to cirrhosis,graft loss and death.Graft and patient survival is reduced in liver transplant recipients with recurrent Hepatitis C virus(HCV) infection compared to HCV-negative recipients.Many variables may impact on recurrent HCV liver disease.Overall,excess immunosuppression is believed to be a key factor;however,no immunosuppressive regimen has been identified to be more beneficial or less harmful.Donor age limitations,exclusion of moderately to severely steatotic livers and minimization of ischemic times could be a potential strategy to minimize the severity of HCV disease in transplanted subjects.After transplantation,antiviral therapy based on pegylated IFN alpha with or without ribavirin is associated with far less results than that reported for immunocompetent HCV-infected patients.New findings in the field of immunotherapy and genomic medicine applied to this context are promising. | Marco Carbone Ilaria Lenci Leonardo Baiocchi | 2012 | World Journal of Gastrointestinal Pharmacology and Therapeutics2012，3，4： | 2 |
| 9 | Thrombus Aspiration During Primary Percutaneous Coronary Intervention Improves Myocardial Reperfusion and Reduces Infarct Size显示文摘 | Gennaro Sardella Massimo Mancone Chiara Bucciarelli-Ducci Luciano Agati Raffaele Scardala Iacopo Carbone Marco Francone Angelo Di Roma Giulia Benedetti Giulia Conti Francesco Fedele | 2009 | Journal of the American College of Cardiology2009，，4： | 1 |
| 10 | Utility of cardiac magnetic resonance (CMR) in the evaluation of right ventricular (RV) involvement in patients with myocardial infarction (MI)显示文摘 | Nicola Galea Marco Francone Iacopo Carbone David Cannata Francesco Vullo Roberto Galea Luciano Agati Francesco Fedele Carlo Catalano | 2014 | La radiologia medica2014，，5： | 1 |
| 11 | Optimal design of driving mechanism in a I-DOF anthropomorphic finger 显示文摘 | Nestor Eduardo Nava Rodriguez Giuseppe Carbone Marco Ceccarelli | 2006 | Mechanism and Machine Theory2006，，41： | 1 |
| 12 | Designing an underactuated mechanism for a 1 active DOF finger oper-ation 显示文摘 | Wu Licheng Giuseppe Carbone Marco Ceccarelli | 2009 | Mechanism and Machine Theory2009，，44： | 1 |
| 13 | Benthic diatom community response to metal contamination from an abandoned Cu mine:Case study of the Gromolo Torrent(Italy)显示文摘Environmental contamination has become a global problem of increasing intensity due to the exponential growth of industrialization. One main debated issue is the metal contamination of rivers receiving Acid Mine Drainage(AMD) from active/abandoned mines. In order to assess the quality of lotic systems, diatoms are commonly used, as their assemblage modifies on the basis of changes in environmental parameters. Benthic diatom changes were analyzed along the metal-impacted Gromolo Torrent(Liguria, NW Italy) with the aim of understanding the effects of input from the abandoned Libiola Cu mine. The results support the hypothesis that metals from AMD lead to massive changes in diatoms, resulting in low biological diversity and in a shift of dominance, passing from the genera Cymbella and Cocconeis to more tolerant and opportunistic species, such as Achnanthidium minutissimum and Fragilaria rumpens. The high concentrations of labile metals, measured through Diffusion Gradients in Thin-films(DGT) immediately downstream of the two AMD inputs in the torrent, corresponded to a sudden decrease in the presence of diatoms, indicating the possible reaching of acute toxic levels. In particular,A. minutissimum dominated the mining area and was positively correlated with Cu and Zn;whereas F. rumpens bloomed downstream of this area, where the metal content was diluted,and was positively correlated with As and Pb. Finally, an important abundance of Nitzschia palea and teratological forms of A. minutissimum and F. rumpens were observed downstream from the mine, indicating that metals may have an important impact on diatoms up to the torrent mouth. | Raffaella Tolotti Sirio Consani Cristina Carbone Greta Vagge Marco Capello Laura Cutroneo | 2019 | Journal of Environmental Sciences2019，31，1： | 1 |
| 14 | 中等传输距离下的无线功率传输链路 第1部分:实现工作状态最优化显示文摘中程无线功率传输(WPT)可以采用几种不同的方式实现,如通过电感或电容耦合、谐振或非谐振网络实现.本文主要研究了通过感应耦合谐振器实现的WPT链路,而且只着重研究了利用2个谐振器的链路(直接链路)并工作在主谐振频率下的情况.研究结果表明,当工作在主谐振频率下,可以根据网络参数来对传输效率或负载功率进行优化. | Alessio De ANGELIS Marco DIONIGI Paolo CARBONE Mauro MONGIARDO 车文荃 王清华 Franco MASTRI Giuseppina MONTI | 2017 | 南京信息工程大学学报(自然科学版)2017，9，1： | 1 |
| 15 | Provenances 显示文摘 | Roberto Tognetii Marco Michelozzi Marco Lauteri Geographic variation in growth carbon isotope discrimination and monoterpene composition in pinus pinaster Air | 2000 | Canadian Journal of Forest Research2000，30，11： | 1 |
| 16 | Alterations of negative regulators of cytokine signalling in immunodeficiency‐related non‐Hodgkin lymphoma显示文摘 | Daniela Capello Annunziata Gloghini Gianluca Baldanzi Maurizio Martini Clara Deambrogi Marco Lucioni Daniela Piranda Rosella Famà Andrea Graziani Michele Spina Umberto Tirelli Marco Paulli Luigi Maria Larocca Gianluca Gaidano Antonino Carbone Fabiola Sini | 2012 | Hematol Oncol2012，，1： | 1 |
| 17 | Videothoracoscopic management of the solitary pulmonary nodule: a single-institution study on 429 cases显示文摘 | Giuseppe Cardillo Mohamed Regal Francesco Sera Marco Di Martino Luigi Carbone Francesco Facciolo Massimo Martelli | 2003 | The Annals of Thoracic Surgery2003，，5： | 1 |
| 18 | A feasibility study on the design and walking operation of a biped locomotor via dynamic simulation显示文摘机械设计和一个一种纸牌戏两足动物的走的操作上的可行性研究运动在这份报纸被介绍。两足动物运动由组成二相同有平行操纵者体系结构的 3 degrees-of-freedom 三脚架腿机制。走步法的两足动物计划被协调二腿机制和腰的运动执行。一个 threedimensional 模型在 SolidWorks 被详细描述吗?环境以便描绘一个可行机械图案。动态模拟在 MSC.ADAMS 被执行吗?有描绘并且评估建议设计的动态走表演的目的环境。与合适的输入运动的建议两足动物线性致动器打手势的模拟结果表演表现实际、可行与有限使活动和反应走在扁平的表面上在它的脚和地面之间强迫。两足动物的一个初步的原型运动为评估走步法的两足动物的操作表演的目的被造求婚运动。 | Mingfeng WANG Marco CECCARELLI Giuseppe CARBONE | 2016 | Frontiers of Mechanical Engineering2016，11，2： | 1 |
| 19 | Recombinant Human Thyrotropin Reduces Serum Vascular Endothelial Growth Factor Levels in Patients Monitored for Thyroid Carcinoma Even in the Absence of Thyroid Tissue显示文摘 | Francesca Sorvillo Gherardo Mazziotti Antonella Carbone Marco Piscopo Mario Rotondi Michele Cioffi Pasquale Musto Bernadette Biondi Sergio Iorio Giovanni Amato Carlo Carella | 2003 | The Journal of Clinical Endocrinology & Metabolism2003，，： | 1 |
| 20 | Thrombus Aspiration During Primary Percutaneous Coronary Intervention Improves Myocardial Reperfusion and Reduces Infarct Size显示文摘 | Gennaro Sardella Massimo Mancone Chiara Bucciarelli-Ducci Luciano Agati Raffaele Scardala Iacopo Carbone Marco Francone Angelo Di Roma Giulia Benedetti Giulia Conti Francesco Fedele | 2009 | Journal of the American College of Cardiology2009，，4： | 1 |
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