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6篇 您的检索式:作者名="MEIXIA MA"
    题名 作者 年代 出处 被引量
1Assessment of an Evapotranspiration Deficit Drought Index in Relation to Impacts on Ecosystems显示文摘Ecosystems have increasingly been subject to the challenge of heavy drought under global warming. To quantitatively evaluate the impacts of drought on ecosystems, it is necessary to develop a drought index that can sensitively depict the response of vegetation to drought evolution at a biological time scale. For the ability of direct connection between climate and ecosystem by deficit of evapotranspiration, in the present study, a drought index was defined based on standardized evapotranspiration deficit (SEDI), according to the difference between actual and potential evapotranspiration, to meet the need for highlighting drought impacts on ecological processes. Comparisons with traditional indices show that SEDI can reasonably detect droughts and climatic dry and wet transitions, especially at a monthly time scale, and can also regenerate long-term trends. Moreover, SEDI can more sensitively capture the biological changes of ecosystems in response to the dynamics of drought intensity, compared with the indices of precipitation and temperature. SEDI is more practical than the precipitation and temperature indices to highlight signals of biological effects in climate droughts. Hence, it has potential for use in assessments of climate change and its impact on ecosystems.Xia ZHANG Mingxing LI Zhuguo MA Qing YANG Meixia LV Robin Clark 2019Advances in Atmospheric Sciences2019,36,11:6
2Co-evolution of plant LTR-retrotransposons and their host genomes显示文摘Transposable elements(TEs),particularly,long terminal repeat retrotransposons(LTR-RTs),are the most abun-dant DNA components in all plant species that have been investigated,and are largely responsible for plant genome size variation.Although plant genomes have experi-enced periodic proliferation and/or recent burst of LTR-retrotransposons,the majority of LTR-RTs are inactivated by DNA methylation and small RNA-mediated silencing mechanisms,and/or were deleted/truncated by unequal homologous recombination and illegitimate recombina-tion,as suppression mechanisms that counteract genome expansion caused by LTR-RT amplifi cation.LTR-RT DNA is generally enriched in pericentromeric regions of the host genomes,which appears to be the outcomes of pref-erential insertions of LTR-RTs in these regions and low effectiveness of selection that purges LTR-RT DNA from these regions relative to chromosomal arms.Potential functions of various TEs in their host genomes remain blurry;nevertheless,LTR-RTs have been recognized to play important roles in maintaining chromatin structures and centromere functions and regulation of gene expres-sions in their host genomes.Meixia Zhao Jianxin Ma 2013Protein & Cell2013,4,7:4
3陆地水循环要素对黄河流域及周边退耕还林的响应(英文)显示文摘退耕还林对水资源的影响复杂且尚存在争议,鉴于此本文基于WRF模式对黄河流域及周边的退耕还林进行了模拟研究,结果表明研究区域的陆地水循环要素对土地利用/覆盖变化较为敏感。在耕地转变为混交林的情况下,黄河流域面平均降水量在2006–2010年间增多223.17 mm,蒸发增加223.88 mm,而产流减少2.22 mm。随着时间增长,植被变化对水资源的影响逐渐增强。对于降水明显偏多和偏少的年份,同一植被变化对水循环要素影响的空间分布不同。LV Meixia MA Zhuguo PENG Shaoming 2019Atmospheric and Oceanic Science Letters2019,12,2:3
4Knowledge Map and Topics Analysis on the Research of Lycoris Research based on the Perspective of Literature Metrology显示文摘[Objective]In order to reflect the relationship between literatures quickly and efficiently and reveal the evolutionary path and hotspot,and predict the future trend of Lycoris researches.[Methods]In 19902019,CiteSpace software was used for visual graphic analysis authors,institutes and key words related to Lycoris research based on data sources of WOS and CNKI.[Results](1)Domestic researchers have formed a core group of authors in East China,but the cooperation between the different teams is relatively dispersed.(2)From the perspective of international cooperation level,the cocontribution in China is the largest.Among them,the Chinese Academy of Sciences published has the largest number of papers,and higher research level.(3)The research on Lycoris has experienced three stages:slow accumulation period,rapid growth period and stable growth period.And its research direction develops along the route of“interspecific relationship within genuspropagation and cultivationpharmacology and pharmacodynamicscytology and molecular biologycross breeding”.[Conclusion]The research of Lycoris mainly distributed in Asian countries such as China and Japan.On the whole,its research direction is developing from macro to micro.MA Meixia WEI Xuying ZHANG Lvshui XU Lina ZHANG Yao CAI Junhuo 2021生物灾害科学2021,44,1:0
5Bushen Yizhi Formula regulates the IRE1αpathway to alleviate endoplasmic reticulum stress in an Alzheimer’s disease rat model显示文摘While the Bushen Yizhi Formula can treat Alzheimer’s disease(AD),the yet to be ascertained specific mechanism of action was explored in this work.Methods:Different concentrations of the Bushen Yizhi Formula and amyloid-beta peptide(Aβ)were used to treat rat pheochromocytoma cells(P12)and human neuroblastoma cells(SH-SY5Y).Cell morphological changes were observed to determine the in vitro cell damage.Cell Counting Kit(CCK)-8 assay and flow cytometry were employed to identify cell viability and apoptosis/cell cycle,respectively.Western blotting and immunohistochemistry were employed to measure the expressions of endoplasmic reticulum stress(ERS)-related proteins(GRP78 and CHOP),p-IRE1α,IRE1α,ASK1,p-JNK,JNK,Bax,Bcl-2,XBP-1,and Bim.Fura 2-acetoxymethyl ester(Fura-2/AM)was used to determine the intracellular calcium(Ca^(2+))concentration.Also,an AD model was constructed by injecting Aβinto the CA1 area of the hippocampus in Sprague Dawley rats.AD model rats were gavaged with different concentrations of Bushen Yizhi Formula for 14 consecutive days.The Morris water maze experiment was conducted to test the learning and memory of rats.Hematoxylin&Eosin(H&E)and Terminal-deoxynucleotidyl Transferase(TdT)-mediated dUTP Nick-End Labeling(TUNEL)staining were done to determine histopathological changes in the brain.Results:Bushen Yizhi Formula relieved the Aβ-induced effects including cell injury,decreased viability,increased apoptosis,G0/G1 phase cell cycle arrest,upregulation of GRP78,CHOP,p-IRE1α,p-JNK,Bax,XBP-1 and Bim,as well as down-regulation of Bcl-2.These results were also seen with IRE1αsilencing.While Aβsuppressed the learning and memory abilities of rats,the Bushen Yizhi Formula alleviated these effects of Aβ.Brain nerve cell injury induced by Aβcould also be treated with Bushen Yizhi Formula.Conclusion:Bushen Yizhi Formula could influence ERS through the IRE1αsignaling pathway to achieve its therapeutic effects on AD.XIRU XU YUAN FANG BIAO ZHANG SHICHAO TENG XIANG WU JING ZHANG XIAOQUN GU MEIXIA MA 2023BIOCELL2023,47,7:0
6A reference-grade genome assembly for Astragalus mongholicus and insights into the biosynthesis and high accumulation of triterpenoids and flavonoids in its roots显示文摘Astragalus membranaceus var.mongholicus(AMM),a member of the Leguminosae,is one of the most important medicinal plants worldwide.The dried roots of AMM have a wide range of pharmacological effects and are a traditional Chinese medicine.Here,we report the first chromosome-level reference genome of AMM,comprising nine pseudochromosomes with a total size of 1.47 Gb and 27868 protein-encoding genes.Comparative genomic analysis reveals that AMM has not experienced an independent wholegenome duplication(WGD)event after the WGD event shared by the Papilionoideae species.Analysis of long terminal repeat retrotransposons suggests a recent burst of these elements at approximately 0.13 million years ago,which may explain the large size of the AMM genome.Multiple gene families involved in the biosynthesis of triterpenoids and flavonoids were expanded,and our data indicate that tandemduplication has been the main driver for expansion of these families.Among the expanded families,the phenylalanine ammonia-lyase gene family was primarily expressed in the roots of AMM,suggesting their roles in the biosynthesis of phenylpropanoid compounds.The functional versatility of 2,3-oxidosqualene cyclase genes in cluster Ⅲ may play a critical role in the diversification of triterpenoids in AMM.Our findings provide novel insights into triterpenoid and flavonoid biosynthesis and can facilitate future research on the genetics and medical applications of AMM.Yi Chen Ting Fang He Su Sifei Duan Ruirui Ma Ping Wang Lin Wu Wenbin Sun Qichen Hu Meixia Zhao Lianjun Sun Xuehui Dong 2023Plant Communications2023,4,2:0
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