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| 1 | Glycoprotein biomarkers for the detection of pancreatic ductal adenocarcinoma显示文摘Pancreatic cancer(Pa C) shows a clear tendency to increase in the next years and therefore represents an important health and social challenge. Currently, there is an important need to find biomarkers for PaC early detection because the existing ones are not useful for that purpose. Recent studies have indicated that there is a large window of time for PaC early detection, which opens the possibility to find early biomarkers that could greatly improve the dismal prognosis of this tumor. The present manuscript reviews the state of the art of the existing PaC biomarkers. It focuses on the anomalous glycosylation process and its role in PaC. Glycan structures of glycoconjugates such as glycoproteins are modified in tumors and these modifications can be detected in biological fluids of the cancer patients. Several studies have found serum glycoproteins with altered glycan chains in PaC patients, but they have not shown enough specificity for PaC. To find more specific cancer glycoproteins we propose to analyze the glycan moieties of a battery of glycoproteins that have been reported to increase in PaC tissues and that can also be found in serum. The combination of these new candidate glycoproteins with their aberrant glycosylation together with the existing biomarkers could result in a panel, which would expect to give better results as a new tool for early diagnosis of PaC and to monitor the disease. | Esther Llop Pedro E Guerrero AdriàDuran Sílvia Barrabés Anna Massaguer María JoséFerri Maite Albiol-Quer Rafael de Llorens Rosa Peracaula | 2018 | World Journal of Gastroenterology2018，24，24： | 4 |
| 2 | Gallbladder drainage guided by endoscopic ultrasound显示文摘The gold-standard management of acute cholecystitis is cholecystectomy.Surgical intervention may be contraindicated due to permanent causes.To date,the classical approach is percutaneous cholecystostomy in patients unresponsive to medical therapy.However, with this treatment some patients may experience discomfort,complications and a decrease in their quality of life.In these cases,endoscopic ultrasound (EUS)-guided gallbladder drainage may represent an effective minimally invasive alternative.Our objective is to describe in detail this new and not well-known technique:EUS-guided cholecystenterostomy.We will describe how the patient should be prepared,what accessories are needed and how the technique is performed.We will also discuss the possible indications for this technique and will provide a brief review based on published reports and our own experience. | José Carlos Súbtil Maite Betes Miguel Muoz-Navas | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，6： | 3 |
| 3 | Long-term follow-up study of gastroduodenal lesions after radioembolization of hepatic tumors显示文摘AIM:To evaluate the long-term natural history of the gastroduodenal lesions secondary to extrahepatic embolization with Ytrium 90(90 Y) spheres.METHODS:From September 2003 to January 2012,379 procedures of liver radioembolization(RE) using resin microspheres loaded with 90 Y were performed in our center.We have retrospectively compiled the data from 379 RE procedures performed in our center.We report a comprehensive clinical,analytical,endoscopic and histologic long-term follow-up of a series of patients who developed gastroduodenal lesions after the treatment.RESULTS:Six patients(1.5%) developed gastrointestinal symptoms and had gastrointestinal lesions as shown by upper endoscopy in the next 12 wk after RE.The mean time between RE and the appearance of symptoms was 5 wk.Only one patient required endoscopic and surgical treatment.The incidence of gastrointestinal ulcerations was 3.75%(3/80) when only planar images were used for the pre-treatment evaluation.It was reduced to 1%(3/299) when singlephoton emission computed tomography(SPECT) images were also performed.The symptoms that lasted for a longer time were nausea and vomiting,until 25 mo after the treatment.CONCLUSION:All patients were free from severe symptoms at the end of follow-up.The routine use of SPECT has decreased the incidence of gastrointestinal lesions due to unintended deployment of 90 Y particles. | Iago Rodríguez-Lago Cristina Carretero Maite Herráiz José C Subtil Maite Betés Macarena Rodríguez-Fraile Jesús J Sola José I Bilbao Miguel Muoz-Navas Bruno Sangro | 2013 | World Journal of Gastroenterology2013，19，19： | 2 |
| 4 | MicroRNAs in biliary diseases显示文摘Cholangiopathies are a group of diseases primarily or secondarily affecting bile duct cells, and result in cholangiocyte proliferation, regression, and/or transformation. Their etiopathogenesis may be associated with a broad variety of causes of different nature, which includes genetic, neoplastic, immune-associated, infectious, vascular, and drug-induced alterations, or being idiopathic. miRNAs, small non-coding endogenous RNAs that post-transcriptionally regulate gene expres sion, have been associated with pathophysiological processes in different organs and cell types, and are postulated as potential targets for diagnosis and therapy. In the current manuscript, knowledge regarding the role of miRNAs in the development and/or progression of cholangiopathies has been reviewed and the most relevant findings in this promising field of hepatology have been highlighted. | Patricia Munoz-Garrido Maite García-Fernández de Barrena Elizabeth Hijona Miguel Carracedo JoséJ G Marín Luis Bujanda Jesús M Banales | 2012 | World Journal of Gastroenterology2012，18，43： | 2 |
| 5 | The LatrorefStudy: Med- ical Errors are Associated with ,Symptoms of Depression in ICU Staff but not Burnout or Safety Culture 显示文摘 | Maite GO Marion P Lilia S | 2015 | Intensive Care Medicine2015，41，2： | 1 |
| 6 | Three-dimensional analysis of subwavelength diffractive optical elements with the finite-difference time-domain method显示文摘 | Dennis W Prather Joseph N Mait | 2000 | Applied Optics2000，39，6： | 1 |
| 7 | Reclaiming of rubber by a renewable resource material (RRM) Part 5 : Assessment of reclaiming of natural rubber/polybut adiene rubber blends and comparison with commercial reclaim rubber显示文摘 | De D Ghosh A K Mait i S | 1999 | Poly- mer Recycling1999，4，3： | 1 |
| 8 | Reclaiming of rubber by a renewable resource material assessment of vulcanized SBR reclaiming process 显示文摘 | De D Mait i S Adhikari B | 2000 | Kautschuk Gummi Kunst soffe2000，53，6： | 1 |
| 9 | Brain Perfusion Correlates of Visuoperceptual Deficits in Mild Cognitive Impairment and Mild Alzheimer’s Disease显示文摘 | Montserrat Alegret Georgina Vinyes-Junqué Mercè Boada Pablo Martínez-Lage Gemma Cuberas Ana Espinosa Isabel Roca Isabel Hernández Sergi Valero Maitée Rosende-Roca Ana Mauleón James T. Becker and Lluís Tárraga | 2010 | Journal of Alzheimer’s Disease2010，，2： | 1 |
| 10 | Three-dimensional analysis of subwavelength diffractive optical dements with the finite-difference time-domain method, applied optics 显示文摘 | Mirotznik Mark S Prather Dennis W Mait Joseph N | 2000 | Applied Optics2000，39，17： | 1 |
| 11 | Matrix metalloproteinase‐10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair显示文摘 | Oihane Garcia‐Irigoyen Simone Carotti Maria U. Latasa Iker Uriarte Maite G. Fernández‐Barrena Maria Elizalde Raquel Urtasun Umberto Vespasiani‐Gentilucci Sergio Morini Jesús M. Banales William C. Parks Jose A. Rodriguez Josune Orbe Jesús Prieto Jose A. Pá | 2014 | Liver Int2014，，7： | 1 |
| 12 | Plant L-ascorbic acid:chemistry,function,metabolism,bioavailability and effects of processing显示文摘 | DAVEY M W MONTAGU M V INZéD S MAITE K ANGELOS S NICHOLAS B IRIS J J S JOHN J F DEREK F JOHN | 2000 | Journal of the Science of Food and Agriculture2000，80，7： | 1 |
| 13 | Rough set based approaches to feature selec- tion for case-based reasoning classifiers显示文摘 | Maria S Maite L | 2011 | Pattern Recognition Letters2011，32，2： | 1 |
| 14 | Caspases regulating death since the origin of life显示文摘 | MAITE S LUKASZ J NATASHA V R | 2005 | Plant Physiology2005，1，137： | 1 |
| 15 | Quality of Life in Functional Dyspepsia显示文摘 | Joan Monés Ana Adan José L. Segú Juan S. López Maite Artés Tina Guerrero | 2002 | Digestive Diseases and Sciences2002，，1： | 1 |
| 16 | Physical properties of edible chitosan filrm containing bergamot essential oil and their inhibitory action on Penicillium italicum显示文摘 | LAURA S G MAITE C AMPARO C | 2010 | Carbohydrate Polymers2010，82，2： | 1 |
| 17 | Orgnizational morphology of rural industry in liberalised India a study of best bengal显示文摘 | Dibyendu s maite | 2005 | Centre for Development Studies Trivendrum Working Papersfrom Centre for Development Studies Triven- drum India2005，2005，6： | 1 |
| 18 | Overexpression of the Arabidopsis CBF3 transcriptional activator mimics multiple biochemical changes associated with cold acclimation 显示文摘 | GILMOUR S J SEBOLT A M MAITE P | 2000 | Plant Phvsiol2000，，124： | 1 |
| 19 | Expression of ascorbate oxidase isoenzymes in cucurbits and during development and ripening of melon fruit 显示文摘 | Al-Madhoun Ashraf S Sanmartin Maite Kanellis Angelos K | 2003 | Postharvest Biology and Technology2003，27，2： | 1 |
| 20 | Use and Users of Electronic Journals at Catalan Universities: The Results of a Survey显示文摘 | Angel Borrego Llu s Anglada Maite Barrios and Nria Comellas | 2007 | Journal of Academic Librarianship2007，，33： | 1 |
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