4篇
您的检索式：作者名="Liu Congyi"
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| 1 | Indoleamine 2,3-dioxygenase and regulatory dendritic cells contribute to the allograft protection induced by infusion of donor-specific splenic stromal cells显示文摘It has been reported that splenic stromal cells(SSCs)are capable of directly supporting the development of CD11c ^(lo)CD45RB^(+) IL-10-producing dendritic cells(DCs)from lineage-negative c-kit^(+) progenitor cells in the absence of exogenous cytokines.In vitro,DCs that differentiate on stromal cells suppress mixed leukocyte reaction responses and induce primary alloreactive CD4^(+) T cells to differentiate into IL-10-producing Tr1 cells.However,the precise mechanisms by which these SSCs exert their regulatory functions in vivo remain undefined.Furthermore,their possible contribution to the development of allograft transplantation tolerance has yet to be examined.Here,we have used both murine skin and cardiac allograft transplantation models to explore whether in vivo alloresponses can be regulated by infusion with donor-derived SSCs and to investigate the possible mechanisms by which SSCs exert regulatory effects to prevent allograft rejection.We show that intravenous SSC infusion prolonged murine skin allograft survival.The prolonged graft survival is associated with augmentation of the generation of regulatory DC subsets and CD4^(+) CD25^(+) Foxp3^(+) regulatory T cells(Tregs),as well as upregulation of the production of suppressive cytokines IL-10 and transforming growth factor(TGF)-b.Moreover,we found that indoleamine 2,3-dioxygenase and SSC-derived regulatory DCs contribute to allograft protection by infusion of donor-specific SSCs.Our data suggest that donor-derived SSCs could be used as a therapeutic target to promote transplantation tolerance. | Li Liu Lihua Duan Min Gong Hong Dai Quan Gong Fang Zheng Zheng Tan Congyi Wang Feili Gong Min Fang | 2011 | Cellular & Molecular Immunology2011，8，1： | 2 |
| 2 | Synthetically evaluation system for multi - source image fu- sion and experiment analysis 显示文摘 | Xiao Gang Jing Zhong liang Wu Jian min Liu Congyi | 2006 | Journal of Shanghai Jiaotong University2006，11，3： | 1 |
| 3 | A Personalized Microbe Biodiversity Dataspace Information System显示文摘It can not provide dynamic view mechanism in previ-ous dataspace information system. In this paper,the dynamic ex-tendable view mechanism provided by object deputy model is proposed for personalized dataspace information system which can provide rich semantics and enough flexibility. The flexible inheritance avoids a lot of data redundancy. The cross class query mechanism allows users to find more related data based on com-plex relationships. The personalized dataspace service provides less storage space consumption and shorter query response time. The experiment result shows that our approach is more feasible and efficient than the traditional one. | LIU Junqiang PENG Zhiyong LI Xuhui ZHENG Congyi FANG Chengxiang | 2007 | Wuhan University Journal of Natural Sciences2007，12，5： | 0 |
| 4 | Revealing the interaction mechanism of pulsed laser processing with the application of acoustic emission显示文摘The mechanisms of interaction between pulsed laser and materials are complex and indistinct,severely infuencing the stability and quality of laser processing.This paper proposes an intelligent method based on the acoustic emission(AE)technique to monitor laser processing and explore the interaction mechanisms.The validation experiment is designed to perform nanosecond laser dotting on foat glass.Processing parameters are set diferently to generate various outcomes:ablated pits and irregular-shaped cracks.In the signal processing stage,we divide the AE signals into two bands,main and tail bands,according to the laser processing duration,to study the laser ablation and crack behavior,respectively.Characteristic parameters extracted by a method that combines framework and frame energy calculation of AE signals can efectively reveal the mechanisms of pulsed laser processing.The main band features evaluate the degree of laser ablation from the time and intensity scales,and the tail band characteristics demonstrate that the cracks occur after laser dotting.In addition,from the analysis of the parameters of the tail band very large cracks can be efciently distinguished.The intelligent AE monitoring method was successfully applied in exploring the interaction mechanism of nanosecond laser dotting foat glass and can be used in other pulsed laser processing felds. | Weinan Liu Youmin Rong Ranwu Yang Congyi Wu Guojun Zhang Yu Huang | 2023 | Frontiers of Optoelectronics2023，16，2： | 0 |
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