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| 1 | Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors显示文摘 | Jing Liao Zhao Wu Ying Wang Lu Cheng Chun Cui Yuan Gao Taotao Chen Lingjun Rao Siye Chen Nannan Jia Huiming Dai Shunmei Xin Jiuhong Kang Gang Pei Lei Xiao | 2008 | Cell Research2008，18，5： | 61 |
| 2 | Generation of hircine-induced pluripotent stem cells by somatic cell reprogramming显示文摘 | Jiangtao Ren Yongjun Pak Lixiazi He Lei Qian Yijun Gu Hui Li Lingjun Rao Jing Liao Chun Cui Xun Xu Jinqiu Zhou Hakchol Ri Lei Xiao | 2011 | Cell Research2011，21，5： | 10 |
| 3 | An Intra-Oceanic Subduction System Influenced by Ridge Subduction in the Diyanmiao Subduction Accretionary Complex of the Xar Moron Area,Eastern Margin of the Central Asian Orogenic Belt显示文摘This study focuses on the geology,geochemistry,Sr-Nd isotopes and their tectonic settings of three types of basalts in Diyanmiao ophiolite in the Xar Moron area located on the eastern margin of the Central Asian Orogenic Belt.Type I basalts are oceanic tholeiites with a depleted light rare earth element(LREE)pattern,which are similar to the typical N-mid-oceanic ridge basalt(MORB)and suggests that they were formed at a mid-oceanic ridge.The initial 87Sr/86Sr ratios of Type I basalts range from 0.703966 to 0.705276 and theεNd(t)values are from 16.49 to 17.15,indicating that they were derived from a depleted mantle source.Type II basalts belong to the medium-potassium calc-akaline series and have the geochem-ical characteristics of Nb-enriched basalt(NEB)with high Nb content(14.5 ppm)and strong enrichment in LREEs,implying that they were created by the partial melting of mantle wedge peridotite that previously metasomatized by slab melts.Type III basalts are high-Al basalt(HAB)with high-Al contents(Al_(2)0_(3)=16.75 wt.%-18.00 wt.%),distinct Nb depletion and high Th/Yb ratios.Thus they were likely gen-erated in a normal island-arc setting.Therefore,the association of MORB,NEB,and HAB in the study area may be due to the subduction of a mid-oceanic ridge,and the Diyanmiao ophiolite is proposed to be formed in the forearc setting of a mid-oceanic ridge subduction system. | Yang Cheng Qinghui Xiao Tingdong Li Liquan Xu Yuxu Fan Yan Li Lingjun Guo Jinli Pang Weiming Yuan | 2021 | Journal of Earth Science2021，32，1： | 6 |
| 4 | Human β-defensin 3 gene modification promotes the osteogenic differentiation of human periodontal ligament cells and bone repair in periodontitis显示文摘Efforts to control inflammation and achieve better tissue repair in the treatment of periodontitis have been ongoing for years.Humanβ-defensin 3,a broad-spectrum antimicrobial peptide has been proven to have a variety of biological functions in periodontitis;however,relatively few reports have addressed the effects of human periodontal ligament cells(h PDLCs)on osteogenic differentiation.In this study,we evaluated the osteogenic effects of h PDLCs with an adenoviral vector encoding humanβ-defensin 3 in an inflammatory microenvironment.Then humanβ-defensin 3 gene-modified rat periodontal ligament cells were transplanted into rats with experimental periodontitis to observe their effects on periodontal bone repair.We found that the humanβ-defensin 3 gene-modified h PDLCs presented with high levels of osteogenesis-related gene expression and calcium deposition.Furthermore,the p38 MAPK pathway was activated in this process.In vivo,humanβ-defensin 3 gene-transfected rat PDLCs promoted bone repair in SD rats with periodontitis,and the p38 mitogen-activated protein kinase(MAPK)pathway might also have been involved.These findings demonstrate that humanβ-defensin 3 accelerates osteogenesis and that humanβ-defensin 3 gene modification may offer a potential approach to promote bone repair in patients with periodontitis. | Lingjun Li Han Jiang Rixin Chen Jing Zhou Yin Xiao Yangheng Zhang Fuhua Yan | 2020 | International Journal of Oral Science2020，12，2： | 5 |
| 5 | Design of good QC-LDPC codes without small girth in the p-plane显示文摘A construction method based on the p-plane to design high-girth quasi-cyclic low-density parity-check (QC-LDPC) codes is proposed. Firstly the good points in every line of the p-plane can be ascertained through filtering the bad points, because the designed parity-check matrixes using these points have the short cycles in Tanner graph of codes. Then one of the best points from the residual good points of every line in the p-plane will be found, respectively. The optimal point is also singled out according to the bit error rate (BER) performance of the QC-LDPC codes at last. Explicit necessary and sufficient conditions for the QC-LDPC codes to have no short cycles are presented which are in favor of removing the bad points in the p-plane. Since preventing the short cycles also prevents the small stopping sets, the proposed construction method also leads to QC-LDPC codes with a higher stopping distance. | Lingjun Kong Yang Xiao | 2011 | Journal of Systems Engineering and Electronics2011，22，2： | 4 |
| 6 | Long-term clinical observation of patients with acute and chronic complete spinal cord injury after transplantation of Neuro Regen scaffold显示文摘Spinal cord injury(SCI)often results in an inhibitory environment at the injury site.In our previous studies,transplantation of a scaffold combined with stem cells was proven to induce neural regeneration in animal models of complete SCI.Based on these preclinical studies,collagen scaffolds loaded with the patients’own bone marrow mononuclear cells or human umbilical cord mesenchymal stem cells were transplanted into SCI patients.Fifteen patients with acute complete SCI and 51 patients with chronic complete SCI were enrolled and followed up for 2 to 5 years.No serious adverse events related to functional scaffold transplantation were observed.Among the patients with acute SCI,five patients achieved expansion of their sensory positions and six patients recovered sensation in the bowel or bladder.Additionally,four patients regained voluntary walking ability accompanied by reconnection of neural signal transduction.Among patients with chronic SCI,16 patients achieved expansion of their sensation level and 30 patients experienced enhanced reflexive defecation sensation or increased skin sweating below the injury site.Nearly half of the patients with chronic cervical SCI developed enhanced finger activity.These long-term follow-up results suggest that functional scaffold transplantation may represent a feasible treatment for patients with complete SCI. | Fengwu Tang Jiaguang Tang Yannan Zhao Jiaojiao Zhang Zhifeng Xiao Bing Chen Guang Han Na Yin Xianfeng Jiang Changyu Zhao Shixiang Cheng Ziqiang Wang Yumei Chen Qiaoling Chen Keran Song Zhiwei Zhang Junjie Niu Lingjun Wang Qin Shi Liang Chen Huilin Yang Shuxun Hou Sai Zhang Jianwu Dai | 2022 | Science China(Life Sciences)2022，65，5： | 3 |
| 7 | Derivation and characterization of human embryonic stem cell lines from the Chinese population显示文摘人的胚胎的干细胞(hESCs ) 无止境地装自我更新并且在人的身体区分进所有房间类型。因此,他们在再生药,人的发展生物学和药发现是珍贵的。很多根 hESC 线从中国人口被导出,但是他们限制了为研究目的是可得到的。这里,我们报导线从中国起源的人的胚囊导出的二 hESC 的推导和描述。这些 hESCs 快车碱的磷酸酶和 hESC 特定的标记,包括的 Oct4, Nanog, SSEA-3, SSEA-4, TRA-1-60 和 TRA-1-81。他们也有 telomerase 活动和正常 karyotypes 的高水平。这些房间能在 vitro 形成胚胎植物或动物身体并且能被 teratoma 形成在 vivo 区分进所有三细菌层。最新确定的 hESCs 将为研究目的被散布。从中国人口的 hESC 线的可获得性将从不同的种族组在 hESCs 在差别上便于研究。 | Zhao Wu Hui Li Lingjun Rao Lixiaz iHe Lei Bao Jing Liao Chun Cui Zhenyu Zuo Qiao Li Huimin Dai Lei Qian Qing Tian Lei Xiao Xiao junTan | 2011 | Journal of Genetics and Genomics2011，38，1： | 3 |
| 8 | Ruling out small stopping sets and small girth in Tanner graph of QC-LDPC code显示文摘The existing constructions of quasi-cyclic low-density parity-check (QC-LDPC) codes do not consider the problems of small stopping sets and small girth together in the Tanner graph, while their existences will lead to the bit error rate (BER) performance of QC-LDPC codes being much poorer than that of randomly constructed LDPC codes even decoding failure. To solve the problem, some theorems of the specific chosen parity-check matrix of QC-LDPC codes without small stopping sets and small girth are proposed. A novel construction for QC-LDPC codes with long block lengths is presented by multiplying mmin or the multiple of mmin, which is the minimum order of the identity matrix for the chosen parity-check matrix. The simulation results show that the specific chosen parity-check matrix of QC-LDPC codes can effectively avoid specified stopping sets and small girth and exhibit excellent BER performance than random LDPC codes with the same longer codes length. | Lingjun Kong Yang Xiao | 2010 | Journal of Systems Engineering and Electronics2010，21，1： | 2 |
| 9 | Antitumor effects of ginsenoside Rg3 on human hepatocellular carcinomacells显示文摘 | Chunle Zhang Lingjun Liu Yang Yu Bin Chen Chengwei Tang Xiao Li | 2012 | Molecular Medicine Reports2012，，5： | 1 |
| 10 | Generation and application of human iPS cells显示文摘Human embryonic stem (ES) cells are capable of unlimited proliferation and maintenance of pluripo-tency in vitro;these properties may lead to potential applications in regenerative medicine. However,immune rejection hampers the allogenic application of human ES cells. Over-expression of several specific transcription factors has been used to reprogram human adult cells into induced pluripotent stem (iPS) cells,which are similar to hESCs in many aspects. The iPS technique makes it possible to produce patient-specific pluripotent stem cells for transplantation therapy without immune rejection. However,some challenges remain,including viral vector integration into the genome,the existence of exogenous oncogenic factors,and low induction efficiency. Here,we review recent advances in human iPS methodology,as well as remaining challenges and its potential applications. | CUI Chun RAO LingJun CHENG LinZhao XIAO Lei | 2009 | Chinese Science Bulletin2009，54，1： | 1 |
| 11 | Antitumor effects of ginsenoside Rg3 on human hepatocellular carcinomacells显示文摘 | Chunle Zhang Lingjun Liu Yang Yu Bin Chen Chengwei Tang Xiao Li | 2012 | Molecular Medicine Reports2012，，5： | 1 |
| 12 | Geochemistry and Tectonic History of Seamount Remnants in the Xingshuwa Subduction Accretionary Complex of the Xar Moron Area,Eastern Margin of the Central Asian Orogenic Belt显示文摘This study focuses on the geology,geochemistry,zircon U-Pb geochronology and tectonic settings of the three types of seamount basalts from the Xingshuwa subduction accretionary complex in the Xar Moron area,eastern margin of the Central Asian Orogenic Belt(CAOB).The seamount remnants are composed of carbonate’cap’sediments,large volumes of pillow and massive basalts,carbonate breccia slope facies and radiolarian cherts.Group 1 basalts are characterized by high contents of P2 O5 and TiO2 with alkaline affinity and LREE enrichment,indicating that they are derived from intraplate magma.Group 2 basalts display N-MORB LREE depletion patterns,indicating that they were formed at a mid-ocean ridge.Group 3 basalts have shown distinct Nb depletion and high Th/Yb ratios,indicating that they were generated in an island arc tectonic setting.The zircon U-Pb age of Group 1 basalt sample XWT18-131 is 576.4±9.4 Ma,suggesting that the oceanic island seamount was the product of intraplate magmatism related to a mantle plume or’hot spot’in the late Neoproterozoic.The zircon U-Pb age of Group 2 basalt sample XWT18-132 is 483±22 Ma,indicating that the Paleo-Asian Ocean(PAO)was continuously expanding in the Early Ordovician.The zircon U-Pb age of Group 3 basalt sample XWT18-101 is 240.5±8.2 Ma,suggesting that this area underwent the evolutionary path of ocean-continent transition,developing towards continentalization during the Middle Triassic.Thus,we believe that there was both mantle plume-related intraplate magmatism and intraoceanic subduction during the evolution of the PAO,the CAOB possibly being an evolutionary model of an intraoceanic subduction and mantle plume magmatism complex. | CHENG Yang XIAO Qinghui LI Tingdong LI Yan FAN Yuxu XU Liquan GUO Lingjun PANG Jinli | 2021 | Acta Geologica Sinica(English Edition)2021，95，4： | 1 |
| 13 | Investigation of the impact of hydrodynamic conditions on sediment resuspension in shallow lakes显示文摘In this study,we sampled the original sediment columns from three points located in the eastern,central,and western areas of Chaohu Lake,and then investigated sediment resuspension under hydraulic disturbances in the laboratory. The results showed that when the hydraulic disturbance is weak and sediment surface shear stress is small (<0.02 N/m²),sediment surface layer moves alone. When the hydraulic disturbance is moderate and sediment surface shear stress is within a threshold (3.7 N/m²),only a small proportion of the surface sediments begins to move. However,when the hydraulic disturbance is further strengthened and sediment surface shear stress is larger than the threshold value,surface sediments move smoothly. By the experimental results,we found that the plankton layer is about 1 mm (1.56% of the maximum content of suspended matter (SSCmax)),which is the major contribution of individual sediment initiation. The new sediment layer is about 19–22 mm (20.9% of the SSCmax),which considerably affects sediment resuspension in shallow lakes. The consolidated layer is about 22 mm below the bed surface,which requires high shear stress and is hard to be transferred to the water column. The quantified experimental observation results are further verified with the theoretical results. | Wenguang Luo Jing Lu Senlin Zhu Yao Yue Lingjun Xiao | 2022 | International Journal of Digital Earth2022，15，1： | 0 |
| 14 | LLR calculation for LDPC coded SCBT in 60 GHz WPAN显示文摘The single-carrier block transmission(SCBT),a.k.a.,single-carrier frequency-domain equalization(SC-FDE),is being considered as an option technique for the wireless personal area network(WPAN) operating at 60 GHz.It is found that for residential environment,in non-line-of-sight(NLOS) multi-path channels,the SCBT is much more effective to combat the inter-symbol interference(ISI) compared with orthogonal frequency division multiplexing(OFDM).Low-density parity-check(LDPC) codes are a class of linear block codes which provide near capacity performance on a large collection of data transmission and storage channels while simultaneously admitting implementable decoders.To facilitate using LDPC codes for SCBT system,a new log-likelihood ratio(LLR) calculation method is proposed based on pilot symbols(PS).Golay Sequences whose sum autocorrelation has a unique peak and zero sidelobe are used for creating the PS.The position and length of the PS are not fixed in the data blocks.The simulation results show that the proposed method can significantly improve the LDPC decoding performance in SCBT system.This is very promising to support ultra high-data-rate wireless transmission. | Lingjun Kong Yang Xiao Ming Lei Ye Huang | 2010 | Journal of Systems Engineering and Electronics2010，21，5： | 0 |
| 15 | Progress in Electrolyte Engineering of Aqueous Batteries in a Wide Temperature Range显示文摘Aqueous rechargeable batteries are safe and environmentally friendly and can be made at a low cost;as such,they are attracting attention in the field of energy storage.However,the temperature sensitivity of aqueous batteries hinders their practical application.The solvent water freezes at low temperatures,and there is a reduction in ionic conductivity,whereas it evaporates rapidly at high temperatures,which causes increased side reactions.This review discusses recent progress in improving the performance of aqueous batteries,mainly with respect to electrolyte engineering and the associated strategies employed to achieve such improvements over a wide temperature domain.The review focuses on fi ve electrolyte engineer-ing(aqueous high-concentration electrolytes,organic electrolytes,quasi-solid/solid electrolytes,hybrid electrolytes,and eutectic electrolytes)and investigates the mechanisms involved in reducing the solidifi cation point and boiling point of the electrolyte and enhancing the extreme-temperature electrochemical performance.Finally,the prospect of further improving the wide temperature range performance of aqueous rechargeable batteries is presented. | Lingjun He Chuyuan Lin Peixun Xiong Hui Lin Wenbin Lai Jingran Zhang Fuyu Xiao Liren Xiao Qingrong Qian Qinghua Chen Lingxing Zeng | 2023 | Transactions of Tianjin University2023，29，5： | 0 |
| 16 | Global warming potential analysis of bio‑jet fuel based on life cycle assessment显示文摘Due to the large amount of greenhouse gas(GHG)emissions and the high dependence on fossil energy,the aviation industry has attracted a lot of attention for emission reduction and sustainable development.Biomass is a green and sustainable renewable resource,and its chemical conversion to produce bio-jet fuel is considered to be an effective way to replace fossil jet fuel and achieve emission reduction.In this study,the cradle-to-grave life cycle analysis is conducted for three bio-jet fuel conversion pathways,including biomass aqueous phase reforming(APR),hydrogenated esters and fatty acids(HEFA),and hydrothermal liquefaction(HTL).Compared with fossil jet fuels,the three bio-jet fuels have a great advantage on global warming potential(GWP),contributing 29.2,43.6 and 51.2 g CO_(2)-eq/MJ respectively.In general,as a relatively new bio-jet fuel conversion technology,the technology of aqueous phase reforming has minimal environmental impact.If the barriers of raw material availability and economy could be broken down,bio-jet fuel will have great development potential in replacing fossil jet fuel and realizing sustainable development. | Xiaonan Zhu Jun Xiao Chenguang Wang Lingjun Zhu Shurong Wang | 2022 | Carbon Neutrality2022，1，1： | 0 |
| 17 | The Interannual and Interdecadal Variations of Tropical Cyclone Affecting Shandong Province显示文摘Based on tropical cyclone yearbook data from 1949 to 2006,climate characteristics,such as interdecadal variation,period of tropical cyclone frequency,rainstorm and strong wind,intensity characteristics,were analyzed. Main results were as follows: tropical cyclone affecting Shandong Province was mainly from the last ten-day of July to the last ten-day of August,and its interdecadal variation was obvious. The marked periodic variation of every 2. 4 and 5 years was found according to power spectrum analysis. It showed obvious weakening tendency about tropical cyclone's intensity by using Kendall test. It also showed that August was the strongest month among a year for rainstorm frequency and intensity,and flood disaster was more easily to occur during this month. It was distinct for frequency's interdecadal variation of tropical cyclone causing rainstorm and strong wind. Marked period was existed about annual average precipitation and strong wind. At the same time,the cause of the variation was discussed. | Gao Xiaomei Wang Lingjun Ma Jinsong Yan Fengjun Xu Guihua Han Xiao Su Lili | 2014 | Meteorological and Environmental Research2014，5，12： | 0 |
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