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| 1 | Essential oils as alternatives to antibiotics in swine production显示文摘This review article summarizes the efficacy, feasibility and potential mechanisms of the application of essential oils as antibiotic alternatives in swine production.Although there are numerous studies demonstrating that essential oils have several properties, such as antimicrobial, antioxidative and antiinflammatory effects, feed palatability enhancement and improvement in gut growth and health, there is still a need of further investigations to elucidate the mechanisms underlying their functions.In the past,the results has been inconsistent in both laboratory and field studies because of the varied product compositions, dosages, purities and growing stages and conditions of animals.The minimal inhibitory concentration(MIC) of essential oils needed for killing enteric pathogens may not ensure the optimal feed intake and the essential oils inclusion cost may be too high in swine production.With the lipophilic and volatile nature of essential oils, there is a challenge in effective delivery of essential oils within pig gut and this challenge can partially be resolved by microencapsulation and nanotechnology.The effects of essential oils on inflammation, oxidative stress, microbiome, gut chemosensing and bacterial quorum sensing(QS) have led to better production performance of animals fed essential oils in a number of studies.It has been demonstrated that essential oils have good potential as antibiotic alternatives in feeds for swine production.The combination of different essential oils and other compounds(synergistic effect) such as organic acids seems to be a promising approach to improve the efficacy and safety of essential oils in applications.High-throughput systems technologies have been developed recently,which will allow us to dissect the mechanisms underlying the functions of essential oils and facilitate the use of essential oils in swine production. | Faith A.Omonijo Liju Ni Joshua Gong Qi Wang Ludovic Lahaye Chengbo Yang | 2018 | Animal Nutrition2018,,2: | 24 |
| 2 | Towards single-molecule optoelectronic devices显示文摘Benefiting from the development of molecular electronics and molecular plasmonics, the interplay of light and electronic transport in molecular junctions has attracted growing interest among researchers in both fields, leading to a new research direction of 'single-molecule optoelectronics'. Here, we review the latest developments of photo-modulated charge transport,electroluminescence and Raman spectroscopy from single-molecule junctions, and suggest future directions for single-molecule optoelectronics. | Lijue Chen Anni Feng Maoning Wang Junyang Liu Wenjing Hong Xuefeng Guo Dong Xiang | 2018 | Science China Chemistry2018,61,11: | 7 |
| 3 | ANALYTICAL MODEL ALGORITHM FOR DYNAMICS OF ROBOTIC MANIPULATORS显示文摘ANALYTICALMODELALGORITHMFORDYNAMICSOFROBOTICMANIPULATORSANALYTICALMODELALGORITHMFORDYNAMICSOFROBOTICMANIPULATORSXuLijuFanShou... | Xu Liju Fan ShouwenChengdu University of Science and TechnologyChen YongSouthwest Jiaotong University | 1995 | Chinese Journal of Mechanical Engineering1995,8,2: | 6 |
| 4 | Effect of TiO_2 nanoparticles on hydrogen evolution reaction activity of Ni coatings显示文摘The electrocatalytic activity of electrodeposited Ni and Ni–TiO_2 coatings with regard to the alkaline hydrogen evolution reaction(HER) was investigated. The Ni coatings were electrodeposited from an acid chloride bath at different current densities, and their HER activities were examined in a 1.0-mol·L^(-1) KOH medium. The variations in the HER activity of the Ni coatings with changes in surface morphology and composition were examined via the electrochemical dissolution and incorporation of nanoparticles. Electrochemical analysis methods were used to monitor the HER activity of the test electrodes; this activity was confirmed via the quantification of gases that evolved during the analysis. The obtained results demonstrated that the Ni–TiO_2 nanocomposite test electrode exhibited maximum activity toward the alkaline HER. The surface appearance, composition, and the phase structure of all developed coatings were analyzed using scanning electron microscopy(SEM), energy dispersive spectroscopy(EDS), and X-ray diffraction(XRD), respectively. The improvement in the electrocatalytic activity of Ni–TiO_2 nanocomposite coating toward HER was attributed to the variation in surface morphology and increased number of active sites. | Revanna Kullaiah Liju Elias Ampar Chitharanjan Hegde | 2018 | International Journal of Minerals,Metallurgy and Materials2018,25,4: | 5 |
| 5 | NUMERICAL SIMULATIONS OF HIGHLY NONLINEAR STEADY AND UNSTEADY FREE SURFACE FLOWS显示文摘A numerical simulation model based on an open source Computational Fluid Dynamics (CFD) package-Open Field Operation and Manipulation (OpenFOAM) has been developed to study highly nonlinear steady and unsteady free surface flows. A two-fluid formulation is used in this model and the free surface is captured using the classical Volume Of Fluid (VOF) method. The incompressible Euler/Navier-Stokes equations are solved using a finite volume method on unstructured polyhedral cells. Both steady and unsteady free surface flows are simulated, which include: (1) a submerged NACA0012 2-D hydrofoil moving at a constant speed, (2) the Wigley hull moving at a constant speed, (3) numerical wave tank, (4) green water overtopping a fixed 2-D deck, (5) green water impact on a fixed 3-D body without or with a vertical wall on the deck. The numerical results obtained have been compared with the experimental measurements and other CFD results, and the agreements are satisfactory. The present numerical model can thus be used to simulate highly nonlinear steady and unsteady free surface flows. | YANG Chi HUANG Fuxin WANG Lijue WAN De-cheng | 2011 | Journal of Hydrodynamics2011,23,6: | 5 |
| 6 | Direct Manufacturing of Net-Shape Functional Components by Laser Consolidation Process (Invited Paper)显示文摘Laser consolidation(LC) is a novel computer-aided manufacturing process developed by the Industrial Materials Institute of National Research Council of Canada(NRC-IMI).This rapid manufacturing process produces net-shape functional metallic parts layer-by-layer directly from a computer aided design(CAD) model by using a laser beam to melt the injected powder and re-solidifying it on the substrate or previous layer.As an alternative to the conventional machining process,this novel manufacturing process builds net-shape functional parts or features on an existing part by adding instead of removing material.In this review paper,LC of CPM-9V tool steel,Ni-based IN-625 and IN-718 superalloys,and Ti-6Al-4V alloy will be discussed.The microstructures and functional properties of these laser consolidated materials will be examined along with several potential industrial applications. | Lijue Xue | 2009 | 中国激光2009,36,12: | 4 |
| 7 | Inhibitory effects of nisin-coated multi-walled carbon nanotube sheet on biofilm formation from Bacillus anthracis spores显示文摘Multi-walled carbon nanotube(MWCNT)sheet was fabricated from a drawable MWCNT forest and then deposited on poly(methyl methacrylate)film.The film was further coated with a natural antimicrobial peptide nisin.We studied the effects of nisin coating on the attachment of Bacillus anthracis spores,the germination of attached spores,and the subsequent biofilm formation from attached spores.It was found that the strong adsorptivity and the super hydrophobicity of MWCNTs provided an ideal platform for nisin coating.Nisin coating on MWCNT sheets decreased surface hydrophobicity,reduced spore attachment,and reduced the germination of attached spores by 3.5 fold,and further inhibited the subsequent biofilm formation by 94.6%compared to that on uncoated MWCNT sheet.Nisin also changed the morphology of vegetative cells in the formed biofilm.The results of this study demonstrated that the anti-adhesion and antimicrobial effect of nisin in combination with the physical properties of carbon nanotubes had the potential in producing effective anti-biofilm formation surfaces. | Xiuli Dong Eric McCoy Mei Zhang Liju Yang | 2014 | Journal of Environmental Sciences2014,26,12: | 4 |
| 8 | Origin,virological features,immune evasion and intervention of SARS-CoV-2 Omicron sublineages显示文摘Recently,a large number of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)variants continuously emerged and posed a major threat to global public health.Among them,particularly,Omicron variant(B.1.1.529),first identified in November 2021,carried numerous mutations in its spike protein(S),and then quickly spread around the world.Currently,Omicron variant has expanded into more than one hundred sublineages,such as BA.1,BA.2,BA.2.12.1,BA.4 and BA.5,which have already become the globally dominant variants.Different from other variants of concern(VOCs)of SARS-CoV-2,the Omicron variant and its sublineages exhibit increased transmissibility and immune escape from neutralizing antibodies generated through previous infection or vaccination,and have caused numerous re-infections and breakthrough infections.In this prospective,we have focused on the origin,virological features,immune evasion and intervention of Omicron sublineages,which will benefit the development of nextgeneration vaccines and therapeutics,including pan-sarbecovirus and universal anti-CoV therapeutics,to combat currently circulating and future emerging Omicron sublineages as well as other SARS-CoV-2 variants. | Shuai Xia Lijue Wang Yun Zhu Lu Lu Shibo Jiang | 2022 | Signal Transduction and Targeted Therapy2022,7,8: | 3 |
| 9 | Exponential stability of impulsive jump linear systems with Markov process显示文摘The exponential stability is investigated for a class of continuous time linear systems with a finite state Markov chain form process and the impulsive jump at switching moments. The conditions, based on the average dwell time and the ratio of expectation of the total time running on all unstable subsystems to the expectation of the total time running on all stable subsystems, assure the exponential stability with a desired stability degree of the system irrespective of the impact of impulsive jump. The uniformly bounded result is realized for the case in which switched system is subjected to the impulsive effect of the excitation signal at some switching moments. | Gao Liju Wu Yuqiang | 2007 | Journal of Systems Engineering and Electronics2007,18,2: | 3 |
| 10 | Life History Recorded in the Vagino-cervical Microbiome Along with Multi-omes显示文摘The vagina contains at least a billion microbial cells,dominated by lactobacilli.Here we perform metagenomic shotgun sequencing on cervical and fecal samples from a cohort of 516 Chinese women of reproductive age,as well as cervical,fecal,and salivary samples from a second cohort of 632 women.Factors such as pregnancy history,delivery history,cesarean section,and breastfeeding were all more important than menstrual cycle in shaping the microbiome,and such information would be necessary before trying to interpret differences between vagino-cervical microbiome data.Greater proportion of Bifidobacterium breve was seen with older age at sexual debut.The relative abundance of lactobacilli especially Lactobacillus crispatus was negatively associated with pregnancy history.Potential markers for lack of menstrual regularity,heavy flow,dysmenorrhea,and contraceptives were also identified.Lactobacilli were rare during breastfeeding or post-menopause.Other features such as mood fluctuations and facial speckles could potentially be predicted from the vagino-cervical microbiome.Gut and salivary microbiomes,plasma vitamins,metals,amino acids,and hormones showed associations with the vagino-cervical microbiome.Our results offer an unprecedented glimpse into the microbiota of the female reproductive tract and call for international collaborations to better understand its long-term health impact other than in the settings of infection or pre-term birth. | Zhuye Jie Chen Chen Lilan Hao Fei Li Liju Song Xiaowei Zhang Jie Zhu Liu Tian Xin Tong Kaiye Cai Zhe Zhang Yanmei Ju Xinlei Yu Ying Li Hongcheng Zhou Haorong Lu Xuemei Qiu Qiang Li Yunli Liao Dongsheng Zhou Heng Lian Yong Zuo Xiaomin Chen Weiqiao Rao Yan Ren Yuan Wang Jin Zi Rong Wang Na Liu Jinghua Wu Wei Zhang Xiao Liu Yang Zong Weibin Liu Liang Xiao Yong Hou Xun Xu Huanming Yang Jian Wang Karsten Kristiansen Huijue Jia | 2022 | Genomics, Proteomics & Bioinformatics2022,20,2: | 2 |
| 11 | Electrical/electrochemical impedance for rapid detection of foodborne pathogenic bacteria显示文摘 | Liju Yang Rashid Bashir | 2007 | Biotechnology Advances2007,,2: | 2 |
| 12 | Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant显示文摘Dear Editor,Most recently,a new SARS-CoV-2 variant of concern(VOC)Z Omicron(B.1.1.529),was first reported to the World Health Organization(WHO)from South Africa and then quickly spread to many countries,1,2 posing a serious threat to current vaccine prevention and antibody therapeutic strategies.Several studies have reported that the Omicron variant successfully escapes from neutralizing antibodies elicited by COVID-19 vaccines or from COVID-19 convalescent patients. | Shuai Xia Jasper Fuk-Woo Chan Lijue Wang Fanke Jiao Kenn Ka-Heng Chik Hin Chu Qiaoshuai Lan Wei Xu Qian Wang Chao Wang Kwok-Yu ng Yuen Lu Lu Shibo Jiang | 2022 | Cell Research2022,32,4: | 2 |
| 13 | Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation显示文摘The COVID-19 pandemic poses a global threat to public health and economy.The continuously emerging SARS-CoV-2 variants present a major challenge to the development of antiviral agents and vaccines.In this study,we identified that EK1 and cholesterol-coupled derivative of EK1,EK1C4,as pan-CoV fusion inhibitors,exhibit potent antiviral activity against SARS-CoV-2 infection in both lung-and intestine-derived cell lines(Calu-3 and Caco2,respectively).They are also effective against infection of pseudotyped SARS-CoV-2 variants B.1.1.7(Alpha)and B.l.1.248(Gamma)as well as those with mutations in S protein,including N417T,E484K,N501Y,and D614G,which are common in South African and Brazilian variants.Crystal structure revealed that EK1 targets the HR1 domain in the SARS-CoV-2 S protein to block virus-cell fusion and provide mechanistic insights into its broad and effective antiviral activity.Nasal administration of EK1 peptides to hACE2 transgenic mice significantly reduced viral titers in lung and intestinal tissues.EK1 showed good safety profiles in various animal models,supporting further clinical development of EK1-based pan-CoV fusion inhibitors against SARS-CoV-2 and its variants. | Shuai Xia Qiaoshuai Lan Yun Zhu Chao Wang Wei Xu Yutang Li Lijue Wang Fanke Jiao Jie Zhou Chen Hua Qian Wang Xia Cai Yang Wu Jie Gao Huan Liu Ge Sun Jan Munch Frank Kirchhoff Zhenghong Yuan Youhua Xie Fei Sun Shibo Jiang Lu Lu | 2021 | Signal Transduction and Targeted Therapy2021,6,8: | 2 |
| 14 | Morphological properties of medial amygdala-projecting retinal ganglion cells in the Mongolian gerbil显示文摘The amygdala is a limbic structure that is involved in many brain functions, including emotion, learning and memory. It has been reported that melanopsin-expressing retinal ganglion cells(ip RGCs) innervate the medial amygdala(Me A). However, whether conventional RGCs(c RGCs) project to the Me A remains unknown. The goal of this study was to determine if c RGCs project to the Me A and to determine the morphological properties of Me A-projecting RGCs(Me A-RGCs). Retrogradely labeled RGCs in whole-mount retinas were intracellularly injected to reveal their dendritic morphologies. Immunohistochemical staining was performed to selectively label ip RGCs(Me A-ip RGCs) and c RGCs(Me A-c RGCs). The results showed that 95.7% of the retrogradely labeled cells were c RGCs and that the rest were ip RGCs. Specifically, Me A-c RGCs consist of two morphological types. The majority of them exhibit small but dense dendritic fields and diffuse ramification patterns as previously reported in RG_(B2)(95%), while the rest exhibit small but sparse dendritic branching patterns resembling those of RG_(B3) cells(5%). Me Aip RGCs consist of M1 and M2 subtypes. The Me A-RGCs showed an even retinal distribution patterns. The soma and dendritic field sizes of the Me A-RGCs did not vary with eccentricity. In conclusion, the present results suggest that Me A-RGCs are structurally heterogeneous. These direct RGCs that input to the Me A could be important for regulating amygdala functions. | Liju Luan Chaoran Ren Wenyao Wang Yan Nan Jie Gao Mingliang Pu | 2018 | Science China(Life Sciences)2018,61,6: | 2 |
| 15 | Antioxidant, Anti-inflammatory and Antinociceptive Properties of Black Pepper Essential Oil (Piper nigrum Linn)显示文摘 | JEENA K LIJU V B UMADEVI N P | 2014 | J Essent Oil Bear Pl2014,,17: | 1 |
| 16 | Synthesis and characterization of folate conjugated chitosan and cellular uptake of its nanoparticles in HT-29 cells显示文摘 | Puwang Li Yichao Wang Fanbo Zeng Lijue Chen Zheng Peng Ling Xue Kong | 2011 | Carbohydrate Research2011,,6: | 1 |
| 17 | Simultaneous detection of Escherichia coli O157:H7 and Salmonella typhimurium using quantum dots asfluorescence labels显示文摘 | YANG Liju LI Yanbin | 2006 | Analyst2006,131,3: | 1 |
| 18 | An over- view on fabrication of three-dimensional woven textile preforms for composites 显示文摘 | CHEN Xiaogang TAYLOR L W TSAI Liju | 2011 | Textile Research Journal2011,,1: | 1 |
| 19 | Inactivation of bacterial pathogens by carbon nanotubes in suspensions显示文摘 | ARIAS L R YANG Liju | 2009 | Langmuir2009,25,5: | 1 |
| 20 | Analytical Model Method for Dynamics of N-celled Tetrahedran-tetrabedran Variable Geometry truss Manipulator 显示文摘 | XU Liju FAN Shouwen HONG Li | 2001 | Mechanism and Machine Theory2001,36,: | 1 |