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| 1 | Efficacy and safety evaluation of intravenous infusion of cervus and cucumis polypeptides for treatment of avascular necrosis of the femoral head: a randomized clinical trial显示文摘OBJECTIVE: To investigate the efficacy and safety of intravenous cervus and cucumis polypeptides for treating avascular necrosis of the femoral head(ANFH) in regard to pain and hip function in a randomized clinical trial.METHODS: A total of 96 subjects with ANFH who were recruited at the Orthopaedic Hospital Affiliated with Hebei United University and Qian Hai Femoral Head Hospital of Beijing were assigned by lottery to an intervention group(n = 48) or a control group(n = 48). All subjects underwent physical therapy and rehabilitation exercises. In addition,subjects in the intervention group were given intravenous infusions of cervus and cucumis polypeptides. Visual analogue scale(VAS), Harris hip score,and radiography or magnetic resonance imaging were applied to assess all subjects at the beginning of treatment and 3, 6, and 9 months afterward. All the subjects were followed up for 2 years.RESULTS: At the beginning of treatment, there were no statistically significant differences between the two groups in terms of the general condition of patients or the VAS and Harris hip scores(all P > 0.05). At 3, 6, and 9 months after treatment,however, the VAS score decreased and the Harris hip score increased in all patients, with the improvement of intervention group significantly greater than that of the control group(P < 0.05).The total effectiveness rates for the intervention and control groups were 89.58% and 70.83%, respectively, with the difference being statistically significant(P < 0.05). There was no statistically significant difference between the two groups in terms of the safety of the injections(P > 0.05).CONCLUSION: Intravenous infusion of cervus and cucumis polypeptides relieved pain and improved hip function of subjects with ANFH.Thus, the intravenous infusion of cervus and cucumis polypeptides was a safe, effective treatment for ANFH. | Wei Liyou Zhang Hongwei Li Xinmin Yang Chunyan Wang Guoqiang Zhang Lifeng Cui Mingwu Han Lijun | 2016 | Journal of Traditional Chinese Medicine2016，36，1： | 15 |
| 2 | Wheat genomic study for genetic improvement of traits in China显示文摘Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestication of wheat,and the genetic basis of agronomically important traits,which promote the breeding of elite varieties.In this review,we focus on progress that has been made in genomic research and genetic improvement of traits such as grain yield,end-use traits,flowering regulation,nutrient use efficiency,and biotic and abiotic stress responses,and various breeding strategies that contributed mainly by Chinese scientists.Functional genomic research in wheat is entering a new era with the availability of multiple reference wheat genome assemblies and the development of cutting-edge technologies such as precise genome editing tools,highthroughput phenotyping platforms,sequencing-based cloning strategies,high-efficiency genetic transformation systems,and speed-breeding facilities.These insights will further extend our understanding of the molecular mechanisms and regulatory networks underlying agronomic traits and facilitate the breeding process,ultimately contributing to more sustainable agriculture in China and throughout the world. | Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong | 2022 | Science China(Life Sciences)2022，65，9： | 9 |
| 3 | Advances in alternating electromagnetic field data processing for earthquake monitoring in China显示文摘The alternating electromagnetic(EM) field is one of the most sensitive physical fields related to earthquakes. There have been a number of publications reporting EM anomalies associated with earthquakes. With increasing applications and research of artificial-source extremely low frequency EM and satellite EM technologies in earthquake studies, the amount of observed data from the alternating EM method increases rapidly and exponentially, so it is imperative to develop suitable and effective methods for processing and analyzing the influx of big data. This paper presents research on the self-adaptive filter and wavelet techniques and their applications to analyzing EM data obtained from ground measurements and satellite observations, respectively. Analysis results show that the self-adaptive filter method can identify both natural- and artificial-source EM signals, and enhance the ratio between signal and noise of EM field spectra, apparent resistivity, and others. The wavelet analysis is capable of detecting possible correlation between EM anomalies and seismic events. These techniques are effective in processing and analyzing massive data obtained from EM observations. | ZHAO GuoZe BI YaXin WANG LiFeng HAN Bing WANG Xiao XIAO QiBin CAI JunTao ZHAN Yan CHEN XiaoBin TANG Ji WANG JiJun | 2015 | Science China Earth Sciences2015，58，2： | 7 |
| 4 | Seismic attributes and integrated prediction of fractured and caved carbonate reservoirs in the Tarim Basin,China显示文摘The carbonate reservoirs in the Tarim Basin are characterized by anisotropy and strong heterogeneity.Combined with an integrated analysis of data from seismic,geology,and drilling results,a series of attributes which are suitable for fractured and caved carbonate reservoir prediction is discussed,including amplitude,coherence analysis,spectra decomposition,seismic absorption attenuation analysis and impedance inversion.Moreover,3-D optimization of these attributes is achieved by integration of multivariate discriminant analysis and principle component analysis,where the logging data are taken as training samples.Using the optimized results,the spatial distribution and configuration features of the caved reservoirs can be characterized in detail.This technique not only improves the understanding of the spatial distribution of current reservoirs but also provides a significant basis for the discovery and production of carbonate reservoirs in the Tarim Basin. | Liu Lifeng Sam Zandong Sun Yang Haijun Han Jianfa Gao Hongliang Jing Bing Zhu Xinghui | 2011 | Petroleum Science2011，8，4： | 6 |
| 5 | Consensus control of stochastic multi-agent systems: a survey显示文摘In this article, we provide a review of the consensus control problem for stochastic multi-agent systems(MASs). Recent advances are surveyed according to the method of occurrence of the stochasticity of the MASs. First, the consensus problem is discussed for MASs, wherein individual agents are corrupted by random noises, i.e., the dynamics of agents involve stochasticity in process and/or measurement equations. Both additive noises and multiplicative noises are surveyed in detail and special attention is paid to the MASs whose dynamics are governed by It?o differential equations. Moreover, particular effort is devoted to presenting the latest progress on the consensus problem for a special type of stochastic MAS with Markovian jump parameters. Subsequently,the relevant research is summarized for MASs with noisy communication environments and stochastic sampling.Further, we provide a systematic review of the consensus problems for MASs whose communication topology varies randomly in the process of data propagation among agents. Finally, conclusions are drawn and several potential future research directions are outlined. | Lifeng MA Zidong WANG Qing-Long HAN Yurong LIU | 2017 | Science China(Information Sciences)2017，60，12： | 5 |
| 6 | Mechanically reprogrammable Pancharatnam-Berry metasurface for microwaves显示文摘Metasurfaces have enabled the realization of several optical functionalities over an ultrathin platform,fostering the exciting field of flat optics.Traditional metasurfaces are achieved by arranging a layout of static meta-atoms to imprint a desired operation on the impinging wavefront,but their functionality cannot be altered.Reconfigurability and programmability of metasurfaces are the next important step to broaden their impact,adding customized on-demand functionality in which each meta-atom can be individually reprogrammed.We demonstrate a mechanical metasurface platform with controllable rotation at the meta-atom level,which can implement continuous Pancharatnam–Berry phase control of circularly polarized microwaves.As the proof-of-concept experiments,we demonstrate metalensing,focused vortex beam generation,and holographic imaging in the same metasurface template,exhibiting versatility and superior performance.Such dynamic control of electromagnetic waves using a single,low-cost metasurface paves an avenue towards practical applications,driving the field of reprogrammable intelligent metasurfaces for a variety of applications. | Quan Xu Xiaoqiang Su Xueqian Zhang Lijuan Dong Lifeng Liu Yunlong Shi Qiu Wang Ming Kang Andrea Alù Shuang Zhang Jiaguang Han Weili Zhang | 2022 | Advanced Photonics2022，4，1： | 5 |
| 7 | Eight darmarane-type saponins isolated from the roots of Panax notoginseng显示文摘Eight darmarane-type saponins,named as sanchirhinoside D(1),3β,6 α-20(S)-6,20-bis(β-D-glucopyranosyloxy)-3-hydroxy dammar-24-en-12-one(2),20(R)-ginsenoside Rg3(3),ginsenosides F2(4)and Rd(5),gypenoside XVII(6),ginsenosides Rb1(7)and ginsenoside V(8)were isolated from the 70%ethanol extract of Panax notoginseng roots by silica gel,octadecyl silane(ODS)column chromatography and HPLC,and identified by chemical and physical methods,especially by spectral analysis.Among them,1 was a new compound and 2 was a new natural product. | Kaunda Joseph Sakah Tao Wang Lili Liu Yue Chen Lifeng Han Yi Zhang | 2013 | Acta Pharmaceutica Sinica B2013，3，6： | 3 |
| 8 | Earthquake Electromagnetic Precursor Anomalies Detected by a New Ground-based Observation Network显示文摘It is a debated topic if there are any observable precursor anomalies prior to the earthquake(EQ hereafter)and if the stronger EQ can be successfully predicted.During last few decades quite a lot of observable electromagnetic(EM)precursors were published by using techniques equipped in either satellites or on ground-based stations.But there are only a few cases that the shortterm precursor anomalies of EM field before earthquakes were observed by using alternate EM fields on ground.This paper will present a new EM observation network built in recent years and show a new finding of EM field with the variation of a one-year cycle observed using the network.As an example,the short-term precursor anomalies of apparent resistivity before the Yangbi EQ(Ms 5.1)occurred on March 27,2017 in Yunnan Province will be studied.The observed anomalous phenomena indicate that the anomaly before the EQ can be captured only if reasonable effective methods including sophisticated analytical techniques are used,and it is believed that continuously observed data on the fixed observation network for a long time is an effective means for studying anomalies that appeared before earthquakes.This network can also play an important role in studying the EM environment from space. | Bing HAN Guoze ZHAO Lifeng WANG Ji TANG Yaxin BI Yan ZHAN Xiaobin CHEN Qibin XIAO Jihong ZHANG | 2021 | Journal of Geodesy and Geoinformation Science2021，4，1： | 3 |
| 9 | Effect of Support Calcination Temperature on Ag Structure and Catalytic Activity for CO Oxidation显示文摘 | ZHANG Xiaodong DONG Han ZHAO Di WANG Yin WANG Yangang CUI Lifeng | 2016 | Chemical Research in Chinese Universities2016，32，3： | 3 |
| 10 | Mapping a mammalian adult adrenal gland hierarchy across species by microwell-seq显示文摘Recently,single-cell RNA-seq technologies have been rapidly updated,leading to a revolution in biology.We previously developed Microwell-seq,a cost-effective and high-throughput single cell RNA sequencing(scRNA-seq)method with a very simple device.Most cDNA libraries are sequenced using an expensive Illumina platform.Here,we present the first report showing combined Microwell-seq and BGI MGISEQ2000,a less expensive sequencing platform,to profile the whole transcriptome of 11,883 individual mouse adult adrenal gland cells and identify 18 transcriptionally distinct clusters.Moreover,we performed a single-cell comparative analysis of human and mouse adult adrenal glands to reveal the conserved genetic networks in these mammalian systems.These results provide new insights into the sophisticated adrenal gland hierarchy and provide a benchmark,low-cost strategy for highthroughput single-cell RNA study. | Shujing Lai Lifeng Ma Weigao E Fang Ye Haide Chen Xiaoping Han Guoji Guo | 2020 | Cell Regeneration2020，9，1： | 2 |
| 11 | Improved strength and ductility of AZ31B Mg alloy sheets processed by accumulated extrusion bonding with artificial cooling显示文摘In this study,accumulated extrusion bonding(AEB)process with application of artificial water cooling was successfully performed to fabricate fined-grains AZ31B Mg alloy sheets at 150℃,200℃ and 250℃.The resultant microstructure and mechanical properties are systematically investigated.It reveals that the processing temperature has an important effect on the microstructural evolution during extrusion.During AEB process at 150℃ and 200℃,{10-12}tensile twinning was activated at early stage of extrusion,and subsequently continuous dynamic recrystallization(CDRX)occurred and dominated the further deformation.However,for the sample extruded at 250℃,hardly any twins can be observed,and new fined dynamic recrystallized grains were found along grain boundaries.Artificial cooling was utilized to reduce the rate of grain growth out of the extrusion die,resulting the grains significantly refined from 11μm to 2.5μm.Local high dislocation density region was also observed in the microstructure of sample processed at 150℃ in artificial cooling condition,and the degree decreased with the processing temperature increase.The results summarized from tensile tests indicated that due to the grain refinement the strength and ductility was significantly enhanced(YS of 186 MPa vs.145 MPa,UTS of 391 MPa vs.336 MPa and FE of 31.5%vs.24.5%compared with the as-received sample).Subsequently,annealing treatment at different temperatures was applied to eliminate the high dislocation density.The sample annealed at 200℃ exhibited the best comprehensive mechanical property with YS of 179 MPa,UTS of 390 MPa and FE of 33.0%.As the annealing temperature increasing,the dislocation density was reduced by static recrystallization(SRX)and grain growth,leading to a decreased strength and ductility. | Tingzhuang Han Jingfeng Zou Guangsheng Huang Lifeng Ma Chaojie Che Weitao Jia Lifei Wang Fusheng Pan | 2021 | Journal of Magnesium and Alloys2021，9，5： | 2 |
| 12 | Student Deep Participation in Library Work: A Chinese Academic Library’s Experience显示文摘 | Lifeng Han Yuan Wang Lili Luo | 2014 | The Journal of Academic Librarianship2014，，5： | 1 |
| 13 | A prozctive approach for simultaneous berth and quay crane scheduling problem with stochastic arrival and han- dling time显示文摘 | HAN Xiaole LU Zhiqiang XI Lifeng | 2010 | European Journal of Operational Re- search2010，207，： | 1 |
| 14 | A heuristic for the quay crane scheduling problem based on contiguous bay crane operations显示文摘 | LU Zhiqiang HAN Xiaole XI Lifeng | 2012 | Computers & Operations Research2012，39，12： | 1 |
| 15 | Preparation of chitosan/grapheme oxide composite film with enhanced mechan- ical strength in the wet state显示文摘 | Han Donglin Yan Lifeng Chen Wufeng | 2011 | Carbohydrate Polymers2011，83，： | 1 |
| 16 | Establishment of the ELF Network in Yunnan and Electromagnetic Precursory Monitoring Results of the Yangbi MS5.1 Earthquake on March 27,2017显示文摘This paper summarizes the layout of the Yunnan seismic ELF electromagnetic observation network,site selection,ELF electromagnetic instrument system,data processing and other construction. The principle and method of using the ELF electromagnetic wave technique to monitor and predict earthquakes are expounded. The long term monitoring of ELF electromagnetic fields is carried out in the Yunnan earthquake prone area,and at the same time,the changes in electrical parameters and spatial electromagnetic fields of the regional crustal medium structure are monitored. The functions such as automatic,quasi real time, remote monitoring, network monitoring, data processing specialization, data service,data sharing and industrialization of the ELF electromagnetic observation data have been realized. In order to capture the deep electromagnetic precursory information of the earthquakes,service for earthquake prediction research,which has broad application prospects and development potential. Through the research of the seismicity of Yunnan in the trial run period of the project,the preliminary results of the extreme low frequency electromagnetic observation of the Yunnan earthquake in recent years are given. The electromagnetic precursors and the electromagnetic effects of the Yangbi earthquake are recorded. In the 3-month period before the earthquake,the power spectrum of the electric and magnetic fields,the apparent resistivity and the impedance phase in the observed signals are all abnormal,and gradually increased with time. The maximum value is reached 20 days before the earthquake,and an earthquake occurs when the change is restored to normal. | Zhang Ping Zhao Guoze Tang Ji Liu Feng Sun Weihuai Han Bing Wang Lifeng Zhang Li | 2018 | Earthquake Research in China2018，32，2： | 1 |
| 17 | Bi-channel near-and far-field optical vortex generator based on a single plasmonic metasurface显示文摘With the recent development of the metasurface,generating an optical vortex in optical far or near fields is realized in various ways.However,to generate vortices in both the near and far fields simultaneously is still a challenge,although it has great potential in the future compact and versatile photonic system.Here,a bi-channel optical vortex generator in both the near and far fields is proposed and demonstrated within a single metasurface,where the surface plasmon vortex and the far-field optical vortex can be simultancously generated under circularly polarized light.The ability of generating vortices with arbitrary topological charges is experimentally demon-strated,which agrces well with simulations.This approach provides great freedom to integrate different vortex generators in a single device and ofers new opprtunities for integrated optical communications,trapping,and other related fields. | QIAO JIANG YANJUN BAO JING LI LIFENG TIAN ToNG CUI LIN SUN BOWEN DU BOWEN LI BENFENG BAI JIA WANG HONGBO SUN Bo SHEN HAN ZHANG FENG LIN XING ZHU ZHEYU FANG | 2020 | Photonics Research2020，8，6： | 1 |
| 18 | Airflow and temperature distribution inside the maxillary sinus: A computational fluid dynamics simulation显示文摘 | Hongrui Zang Yingxi Liu Demin Han Luo Zhang Tong Wang Xiuzhen Sun Lifeng Li | 2012 | Acta Oto-Laryngologica2012，，6： | 1 |
| 19 | Information and Reference Services in the Digital Library显示文摘 | Han Lifeng Goulding A | 2003 | Information Services and Use2003，23，4： | 1 |
| 20 | Research on the hydraulic system of hydraulic rolling shear显示文摘 | HAN Heyong HUANG Qingxue MA Lifeng | 2011 | Journal of Sichuan University2011，43，23： | 1 |
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