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| 1 | Enhancement of vitamin A combined vitamin D supplementation on immune response to Bacille Calmette-Guerin vaccine revaccinated in Chinese infants显示文摘Objective:To investigate whether there is an association between diameter of bacille CalmetteGuerin(BCG)sears and effect of purified protein derivative(PPD)reaction anil to determine whether vitamin A(VA)combined vitamin I)(VD)supplementation influences the immune response to BCG revueeinated in Chinese infants.Methods:A cross-section and 3-month community-randomised trial was conducted.A total of 5 629 infants at 3,6 and 12 months of age in Junan County of China were examined for BCG scar fonnation.Then,597 revuccinated infants were randomly assigned to supplementation(n=307)and control(n=290)groups.The supplementation group were daily assigned to 1 500 IU VA and 500 IU VD for 3 months.Then all infants were subjected to skin test with PPD.Results:The diameter of BCG sears was positively con-elated with diameter of skin indurations of PPD(r=0.17,P<0.05)in the 5 629 infants.The rate of positive response to PP1)was higher in the supplementation group than in the control group(96.1%versus 89.7%,P<0.05,prevalence ratio 1.07.95%CI 1.02-1.12).The prevalence ralio of PPD response for the supplementation group compared with that for the control group was 1.07(95%CI 1.01-1.13)for the males and 1.08(95%CI 1.00-1.17)for the females.For the supplementation group,the males got larger tuberculin induration than the females[(0.73±0.2l)cm versus(0.67±0.20)cm.P<0.05)after intervention.Conclusions:The diameter of BCG scars was effectively correlated with PPD response,which indicates BCG scar formation may be an useful tool Io evaluate the effect of tuberculosis prevention.VA combined VD supplementation may play an immunoregulatory rale in BCG revuecination.This may contribute to the prevention of childhood tuberculosis. | Ying Zheng Xue-Gang Li Qiu-Zhen Wang Ai-Guo Ma Ib Christian Bygbjerg Yong-Ye Sun Yong Li Ming-Ci Zheng Xi Wang | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，2： | 3 |
| 2 | Hypoxia induces escape from innate immunity in cancer ceils via increased expression of ADAM10: role of nitric oxide显示文摘 | Barsoum IB Hamilton TK Li X | 2011 | Cancer Res2011，71，24： | 1 |
| 3 | Protein kinase C beta enhances growth and expression of cyclin D1 in human breast cancer cells 显示文摘 | Li H Weinstein IB | 2006 | Cancer Res2006，66，11： | 1 |
| 4 | Hypoxia induces escapefrom innate immunity in cancer cells via increased expression ofADAM10:role of nitric oxide显示文摘 | Barsoum IB Hamilton TK Li X | 2011 | Cancer Res2011，71，24： | 1 |
| 5 | Coordinated regulation of anthocyanin biosynthesis in Chinese bayberry (Myrica rubra) fruit by a R2R3 MYB transcription factor显示文摘 | Niu SS Xu CJ Zhang WS Zhang B Li X Lin-Wang K Ferguson IB Allan AC Chen KS | 2010 | Planta2010，231，4： | 1 |
| 6 | Asthma in childrenand adolescents:socio -economic and psycho -somatic considera-tions显示文摘 | ChivuRD Chivu LI Iamandescu IB | 2007 | Pneumologia2007，56，3： | 1 |
| 7 | Partial discharge monitoring forpower transformers using UHF sensors part2:field experience显示文摘 | Judd M D Yang Li Hunter IB | 2005 | IEEE Electrical Insulation Magazine2005，21，3： | 1 |
| 8 | Extraction of total RNA from Chrysanthemumcontaining high levels of phenolic and carbohydrates显示文摘 | Wang DH Wang BC Li IB | 2004 | Colloid Surfaces B:Biointerfaces2004，36，： | 1 |
| 9 | Comparison of antiretroviral ad- herence questions 显示文摘 | Berg KM Wilson IB Li X | 2012 | AIDS and behavior2012，16，2： | 1 |
| 10 | The effect of shoe sole tread groove depth on the friction coefficient with different tread groove widths, floors and contaminants 显示文摘 | LI K W Ib'U H H LIN Y C | 2006 | Applied Ergonomics2006，37，6： | 1 |
| 11 | Histidine triad nucleotide-binding protein 1 up-regulates cellular levels of p27KIP1 by targeting ScfSKP2 ubiquitin ligase and Src显示文摘 | Cen B Li H Weinstein IB | 2009 | J Biol Chem2009，284，8： | 1 |
| 12 | Protein kinase C beta enhances growth and expression of cyclin D1 in human breast cancer cells 显示文摘 | Li H Weinstein IB | 2006 | Cancer Res2006，66，11： | 1 |
| 13 | Characterization of Rice black-streaked dwaoe virus- and Rice stripe virus-Derived siRNAs in singly and doubly infected insect vector Laodelphax striatellus显示文摘 | Li JM Andika IB Shen JF | 2013 | PLoS One2013，8，66： | 1 |
| 14 | Microbiota of a seepage face at the mouth of a subterranean estuary:diversity,distribution and substrate dependence显示文摘Subterranean estuaries,i.e.,the mixing zone between terrestrial groundwater and recirculated seawater,host a wide range of microbiota.Here,field campaigns were conducted at the mouth of the subterranean estuary at the Sanggou Bay(Shandong Province,China)over four consecutive seasons at a seepage face(0−20 cm depth).The diversity of benthic microbiome was characterized via 16S rRNA gene sequencing and metagenomics,combined with physic-chemical parameters,e.g.,organic carbon,total nitrogen and sulfate contents in sediments.During spring,the dominant species were assigned to the phylum Proteobacteria.Important opportunistic species was assigned to Acidobacteria,Actinobacteria and Bacteroidetes.The key components were identified to be species of the genera Pseudoalteromonas,Colwellia and Sphingobium,indicating the involvement of sediment microbiota in the degradation of sedimentary organic carbon,particularly that of pelagic origin,e.g.,phytoplankton detritus and bivalve pseudo-feces.During spring,the microbial community was statistically similar along the depth profiles and among the three sampled stations.Similar spatial distributions were obtained in the remaining seasons.By contrast,the dominant species assemblages varied significantly among seasons,with key genera being Thioprofundum and Nitrosopumilus during summer and autumn and Thioprofundum and Ilumatobacter during winter.Network analysis revealed a seasonal shift in benthic nitrogen and sulfur metabolism associated with these variations in microbial community composition.Overall,our findings suggested that macro elements derived from pelagic inputs,particularly detrital phytoplankton,shaped the microbial community compositions at the seepage face,resulting in significant seasonal variations,while the influence of terrestrial materials transported by groundwater on the sediment microbiota at the seepage face found to be minor. | Yueming Wu Yongjun Wei Juan Severino Pino Ibánhez Danqing Sun Kaiqi Lu Qianqian Wang Jian Li Shan Jiang | 2023 | Acta Oceanologica Sinica2023，42，8： | 0 |
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