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| 1 | An Introductory Overview of Earthquake Early Warning显示文摘Earthquake early warning(EEW)is discriminated from earthquake prediction by using initial seismic waves to predict the severity of ground motion and issue the warning information to potential affected area.The warning information is useful to mitigate the disaster and decrease the losses of life and economy.We reviewed the development history of EEW worldwide and summarized the methodologies using in different systems.Some new sensors came and are coming into EEW giving more developing potential to future implementation.The success of earthquake disaster mitigation relies on the cooperation of the whole society. | SUN Li DENG Wenze DAI Danqing | 2019 | Earthquake Research in China2019，33，4： | 2 |
| 2 | Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration显示文摘 | Yujing Zhang Danqing Liu Xi Chen Jing Li Limin Li Zhen Bian Fei Sun Jiuwei Lu Yuan Yin Xing Cai Qi Sun Kehui Wang Yi Ba Qiang Wang Dongjin Wang Junwei Yang Pingsheng Liu Tao Xu Qiao Yan Junfeng Zhang Ke Zen Chen-Yu Zhang | 2010 | Molecular Cell2010，，1： | 2 |
| 3 | Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration显示文摘 | Yujing Zhang Danqing Liu Xi Chen Jing Li Limin Li Zhen Bian Fei Sun Jiuwei Lu Yuan Yin Xing Cai Qi Sun Kehui Wang Yi Ba Qiang Wang Dongjin Wang Junwei Yang Pingsheng Liu Tao Xu Qiao Yan Junfeng Zhang Ke Zen Chen-Yu Zhang | 2010 | Molecular Cell2010，，1： | 1 |
| 4 | Microbiota of a seepage face at the mouth of a subterranean estuary:diversity,distribution and substrate dependence显示文摘Subterranean estuaries,i.e.,the mixing zone between terrestrial groundwater and recirculated seawater,host a wide range of microbiota.Here,field campaigns were conducted at the mouth of the subterranean estuary at the Sanggou Bay(Shandong Province,China)over four consecutive seasons at a seepage face(0−20 cm depth).The diversity of benthic microbiome was characterized via 16S rRNA gene sequencing and metagenomics,combined with physic-chemical parameters,e.g.,organic carbon,total nitrogen and sulfate contents in sediments.During spring,the dominant species were assigned to the phylum Proteobacteria.Important opportunistic species was assigned to Acidobacteria,Actinobacteria and Bacteroidetes.The key components were identified to be species of the genera Pseudoalteromonas,Colwellia and Sphingobium,indicating the involvement of sediment microbiota in the degradation of sedimentary organic carbon,particularly that of pelagic origin,e.g.,phytoplankton detritus and bivalve pseudo-feces.During spring,the microbial community was statistically similar along the depth profiles and among the three sampled stations.Similar spatial distributions were obtained in the remaining seasons.By contrast,the dominant species assemblages varied significantly among seasons,with key genera being Thioprofundum and Nitrosopumilus during summer and autumn and Thioprofundum and Ilumatobacter during winter.Network analysis revealed a seasonal shift in benthic nitrogen and sulfur metabolism associated with these variations in microbial community composition.Overall,our findings suggested that macro elements derived from pelagic inputs,particularly detrital phytoplankton,shaped the microbial community compositions at the seepage face,resulting in significant seasonal variations,while the influence of terrestrial materials transported by groundwater on the sediment microbiota at the seepage face found to be minor. | Yueming Wu Yongjun Wei Juan Severino Pino Ibánhez Danqing Sun Kaiqi Lu Qianqian Wang Jian Li Shan Jiang | 2023 | Acta Oceanologica Sinica2023，42，8： | 0 |
| 5 | A Distributed LRTCO Algorithm in Large-Scale DVE Multimedia Systems显示文摘In the large-scale Distributed Virtual Environment(DVE)multimedia systems,one of key challenges is to distributedly preserve causal order delivery of messages in real time.Most of the existing causal order control approaches with real-time constraints use vector time as causal control information which is closely coupled with system scales.As the scale expands,each message is attached a large amount of control information that introduces too much network transmission overhead to maintain the real-time causal order delivery.In this article,a novel Lightweight Real-Time Causal Order(LRTCO)algorithm is proposed for large-scale DVE multimedia systems.LRTCO predicts and compares the network transmission times of messages so as to select the proper causal control information of which the amount is dynamically adapted to the network latency variations and unconcerned with system scales.The control information in LRTCO is effective to preserve causal order delivery of messages and lightweight to maintain the real-time property of DVE systems.Experimental results demonstrate that LRTCO costs low transmission overhead and communication bandwidth,reduces causal order violations efficiently,and improves the scalability of DVE systems. | Hangjun Zhou Guang Sun Sha Fu Wangdong Jiang Tingting Xie Danqing Duan | 2018 | Computers, Materials & Continua2018，，7： | 0 |
| 6 | The regulators of BCR signaling during B cell activation显示文摘B lymphocytes produce antibodies under the stimulation of specific antigens,thereby exerting an immune effect.B cells identify antigens by their surface B cell receptor(BCR),which upon stimulation,directs the cell to activate and differentiate into antibody generating plasma cells.Activation of B cells via their BCRs involves signaling pathways that are tightly controlled by various regulators.In this review,we will discuss three major BCR mediated signaling pathways(the PLC-g2 pathway,PI3K pathway and MAPK pathway)and related regulators,which were roughly divided into positive,negative and mutual-balanced regulators,and the specific regulators of the specific signaling pathway based on regulatory effects. | Yue Wen Yukai Jing Lu Yang Danqing Kang Panpan Jiang Na Li Jiali Cheng Jingwen Li Xingbo Li Zican Peng Xizi Sun Heather Miller Zhiwei Sui Quan Gong Boxu Ren Wei Yin Chaohong Liu | 2019 | Blood Science2019，1，2： | 0 |
| 7 | Liver spheroids on chips as emerging platforms for drug screening显示文摘Liver plays a critical role in drug metabolism and nowadays multi-cellular culture systems aiming at imitating liver-specific morphology and functionality are advancing robustly.Numerous immortalized or stem cell-induced hepatic cell lines have been investigated to enhance the hepatic phenotype in establishing co-culture systems.Owing to the robust progresses of microtechnology and bioengineering,two-dimensional(2D)co-cultures such as sandwich culture and micropatterned co-culture systems have emerged.Controllably arranging the hepatocytes and fibroblasts allows bio-mimic homotypic and heterotypic interactions,and the miniaturized co-culture platform realizes high-throughput and sensitive drug screening.Yet,to address the rapid dedifferentiation and the decreased maintenance of hepatic functions existing in 2D cellular systems,various three-dimensional(3D)and dynamic hepatocyte co-culturing formats have been established to obtain more physiologically relevant liver microsystems and prolonged hepatic functionalities,such as spheroid barcodes,liver organoids,bioengineered hepatic spheroids,and microfluidic perfused liver-on-a-chip.In this review,we first introduce the typical structural color spheroid barcodes which facilitate multiple screening and testing.Then we sketch various advances in liver-imitating cellular co-culture protocols through representative examples.Meanwhile,we summarize current difficulties and propose the prospects of bioengineered liver-on-barcode systems for reliable and high-throughput drug screening. | Danqing Huang Xiaoxuan Zhang Xiao Fu Yan Zu Weijian Sun Yuanjin Zhao | 2021 | Engineered Regeneration2021，2，1： | 0 |
| 8 | Practice of reperfusion in patients with ST-segment elevation myocardial infarction in China:findings from the Improving Care for Cardiovascular Disease in China–Acute Coronary Syndrome project显示文摘Background:Reperfusion therapy is fundamental for ST-segment elevation myocardial infarction(STEMI).However,the details of contemporary practice and factors associated with reperfusion therapy in China are largely unknown.Therefore,this study aimed to explore reperfusion practice and its associated factors among hospitalized patients with STEMI in China.Methods:Patients with STEMI who were admitted to 159 tertiary hospitals from 30 provinces in China were included in the Improving Care for Cardiovascular Disease in China–Acute Coronary Syndrome project from November 2014 to December 2019.The associations of the characteristics of patients and hospitals with reperfusion were examined using hierarchical logistic regression.The associations between therapies and in-hospital major adverse cardiovascular events were examined with a mixed effects Cox regression model.Results:Among the 59,447 patients,37,485(63.1%)underwent reperfusion,including 4556(7.7%)receiving fibrinolysis and 32,929(55.4%)receiving primary percutaneous coronary intervention(PCI).The reperfusion rate varied across geographical regions(48.0%–73.5%).The overall rate increased from 60.0%to 69.7%from 2014 to 2019,mainly due to an increase in primary PCI within 12 h of symptom onset.Timely PCI,but not fibrinolysis alone,was associated with a decreased risk of inhospital major adverse cardiovascular events compared with no reperfusion,with an adjusted hazard ratio(95%confidence interval)of 0.64(0.54,0.76)for primary PCI at<12 h,0.53(0.37,0.74)for primary PCI at 12 to 24 h,0.46(0.25,0.82)for the pharmaco-invasive strategy,and 0.79(0.54,1.15)for fibrinolysis alone.Conclusions:Nationwide quality improvement initiatives should be strengthened to increase the reperfusion rate and reduce inequality in China.Trial registration:www.ClinicalTrials.gov,NCT02306616。 | Yiqian Yang Yongchen Hao Jun Liu Na Yang Danqing Hu Zhaoqing Sun Dong Zhao Jing Liu on behalf of the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome(CCC-ACS)Investigators | 2022 | Chinese Medical Journal2022，135，23： | 0 |
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