4篇
您的检索式：作者名="Li Fanbiao"
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| 1 | Nonfragile outputtracking control of hypersonic air-breathing vehicleswith an LPV model显示文摘 | Wu Ligang Yang Xuebo Li Fanbiao | 2013 | IEEE-ASME Transactions onMechatronics2013，18，4： | 1 |
| 2 | Integral Event-Triggered Attack-Resilient Control of Aircraft-on-Ground Synergistic Turning System With Uncertain Tire Cornering Stiffness显示文摘This article proposes an integral-based event-triggered attack-resilient control method for the aircraft-on-ground(AoG) synergistic turning system with uncertain tire cornering stiffness under stochastic deception attacks. First, a novel AoG synergistic turning model is established with synergistic reverse steering of the front and main wheels to decrease the steering angle of the AoG fuselage, thus reducing the steady-state error when it follows a path with some large curvature. Considering that the tire cornering stiffness of the front and main wheels vary during steering, a dynamical observer is designed to adaptively identify them and estimate the system state at the same time.Then, an integral-based event-triggered mechanism(I-ETM) is synthesized to reduce the transmission frequency at the observerto-controller end, where stochastic deception attacks may occur at any time with a stochastic probability. Moreover, an attackresilient controller is designed to guarantee that the closed-loop system is robust L2-stable under stochastic attacks and external disturbances. A co-design method is provided to get feasible solutions for the observer, controller, and I-ETM simultaneously. An optimization program is further presented to make a tradeoff between the robustness of the control scheme and the saving of communication resources. Finally, the low-and high-probability stochastic deception attacks are considered in the simulations. The results have illustrated that the AoG synergistic turning system with the proposed control method follows a path with some large curvature well under stochastic deception attacks. Furthermore,compared with the static event-triggered mechanisms, the proposed I-ETM has demonstrated its superiority in saving communication resources. | Chenglong Du Fanbiao Li Yang Shi Chunhua Yang Weihua Gui | 2023 | IEEE/CAA Journal of Automatica Sinica2023，10，5： | 1 |
| 3 | N-cadherin regulates osteogenesis and migration of bone marrow-derived mesenchymal stem cells显示文摘 | Liangliang Xu Fanbiao Meng Ming Ni Yukwai Lee Gang Li | 2013 | Molecular Biology Reports2013，，： | 1 |
| 4 | Inhibition of apoptosis-regulatory protein Siva-1 reverses multidrug resistance in gastric cancer by targeting PCBP1显示文摘Introduction:Siva-1,as a pro-apoptotic protein,has been shown to induce extensive apoptosis in a number of different cell lines.In our previous study,we showed that overexpressed Siva-1 decreased the apoptosis of gastric cancer cells.So,we believe that it can also work as an anti-apoptotic protein.The present study aimed to determine the specific role of Siva-1 in anticancer drug resistance in gastric cancer in vivo and in vitro and preliminarily reveal the mechanism.Materials and Methods:A vincristine-resistant MKN-28/VCR gastric cancer cell line with stably downregulated Siva-1 was established.The effect of Siva-1 downregulation on chemotherapeutic drug resistance was assessed by measuring the IC50 and pump rate of doxorubicin.Proliferation,apoptosis of cells,and cell cycle were detected via colony formation assay andflow cytometry,respectively.Additionally,migration and invasion of cells was detected via wound healing and transwell assays.Moreover,we determined in vivo effects of LV-Siva-1-RNAi on tumor size,and apoptotic cells in tumor tissues were detected using TUNEL and hematoxylin and eosin staining.Results:Siva-1 downregulation reduced the pump rate of doxorubicin and enhanced the response to drug treatment.Siva-1 negatively regulated proliferation and promoted apoptosis of cells by potentiality G2-M phase arresting.Inhibition of Siva-1 expression in MKN-28/VCR cells significantly weakened wound healing ability and decreased invasion ability.Poly(C)-binding protein 1(PCBP1)was identified as a Siva-1-interacting protein in yeast two-hybrid screening.Semiquantitative RT-PCR and western blotting revealed that Siva-1 downregulation could inhibit expression of PCBP1,Akt,and NF-κB and eventually decrease the expression of MDR1 and MRP1.Conclusion:The current study demonstrated that the downregulation of Siva-1,which functions as a regulator of MDR1 and MRP1 gene expression in gastric cancer cells by inhibiting PCBP1/Akt/NF-κB signaling pathway expression,enhanced the sensitivity of gastric cancer cells to certain chemotherapies. | FANBIAO KONG KUN WU LIMING PANG YULIANG HUANG LEI LI JING XU FEITONG LI YAN QING ZHONGYU WANG XIURONG HUANG SHENG XU XIAOGANG ZHONG ZHOU ZHU XIAOTONG WANG JIANRONG YANG | 2022 | Oncology Research2022，30，6： | 0 |
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