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| 1 | New Insights into Aluminum Tolerance in Rice: The ASR5 Protein Binds the STAR1 Promoter and Other Aluminum-Responsive Genes显示文摘在植物的铝(艾尔) 毒性是在庄稼生产的主要限制之一。艾尔 3+, 最艾尔的有毒的形式,在酸的条件和原因下面被释放进土壤植物的广泛的损坏, especiallyin 根。在米饭,艾尔忍耐要求 ASR5 基因,而是 ASR5 的分子的功能仍然保持未知。这里,我们执行染色体宽的分析在米饭识别 ASR5-dependentAl-responsive 基因。在植物把 silencing 基于 ASR5_RNAi,全球 transcriptome 分析识别了全部的 of961 对在野类型的米饭根的艾尔处理应答的基因。这些基因, 909 没在 ASR5_RNAiplants 对艾尔作出回应,显示为在 Al 应答的基因表示的 ASR5 的一个中央角色。在正常条件下面,没有艾尔处理, ASR5_RNAi 植物与野类型的植物相比表示了 1.756 基因差别,并且在野类型的植物的 446 这些基因 respondedto 艾尔处理。深定序跟随的染色质 immunoprecipitation 识别了被对他们的倡导者有约束力的 ASR5 直接调整的 104 putativetarget 基因,包括 STAR1 基因,它编码为艾尔忍耐要求的 ABC transporter。有约束力的山峰序列的主题分析为 ASR5 揭示了 thebinding 主题,它在 vitro 被证实经由用 STAR1 倡导者的 DNA 有约束力的试金。这些结果证明 ASR5 充当在 rice.Key 词为 Al 应答的 geneexpression 和艾尔忍耐是必要的一个关键抄写因素: | Rafael Augusto Arenhart Yang Bai Luiz Felipe Valter de Oliveira Lauro Bucker Neto Mariana Schunemann Felipe dos Santos Maraschin Jorge Mariath Adriano Silverio Gilberto Sachetto-Martins Rogerio Margis Zhi-Yong Wang Marcia Margis-Pinheiro | 2014 | Molecular Plant2014，7，4： | 12 |
| 2 | Prophylaxis for venous thromboembolism after resection of hepatocellular carcinoma on cirrhosis: Is it necessary?显示文摘AIM: To assess the safety and effectiveness of prophylaxis for venous thromboembolism (VTE) in a large population of patients with hepatocellular carcinoma (HCC) on cirrhosis.METHODS: Two hundred and twenty nine consecutive cirrhotic patients with HCC who underwent hepatic resection were retrospectively evaluated to assess whether there was any difference in the incidence of thrombotic or hemorrhagic complications between those who received and those who did not receive prophylaxis with low-molecular weight heparin.Differences and possible effects of the following parameters were investigated: age,sex,Child-Pugh and model for end-stage liver disease (MELD) score,platelet count,presence of esophageal varices,type of hepatic resection,duration of surgery,intraoperative transfusion of blood and fresh frozen plasma (FFP),body mass index,diabetes and previous cardiovascular disease.RESULTS: One hundred and fifty seven of 229 (68.5%) patients received antithromboembolic prophylaxis (group A) while the remaining 72 (31.5%) patients did not (group B).Patients in group B had higher Child-Pugh and MELD scores,lower platelet counts,a higher prevalence of esophageal varices and higher requirements for intraoperative transfusion of FFP.The incidence of VTE and postoperative hemorrhage was 0.63% and 3.18% in group A and 1.38% and 1.38% in group B,respectively;these differences were not significant.None of the variables analyzed including prophylaxis proved to be risk factors for VTE,and only the presence of esophageal varices was associated with an increased risk of bleeding.CONCLUSION: Prophylaxis is safe in cirrhotic patients without esophageal varices;the real need for prophylaxis should be better assessed. | Marco Vivarelli Matteo Zanello Chiara Zanfi Alessandro Cucchetti Matteo Ravaioli Massimo Del Gaudio Matteo Cescon Augusto Lauro Eva Montanari Gian Luca Grazi Antonio Daniele Pinna | 2010 | World Journal of Gastroenterology2010，16，17： | 6 |
| 3 | Femtosecond laser-assisted deep anterior lamellar keratoplasty in phototherapeutic keratectomy versus the big-bubble technique in keratoconus显示文摘AIM:To compare the functional and anatomic results of femtosecond laser(FSL)-assisted deep anterior lamellar keratoplasty(DALK) associated with phototherapeutic keratectomy(PTK) and FSL-assisted DALK performed using the big-bubble technique in keratoconus.METHODS:During the first phase of the study,an electron microscopy histopathology pilot study was conducted that included four unsuitable donor corneas divided into two groups:in FSL group,FSL lamellar cuts were performed on two corneas and in FSL+PTK group,PTK was performed at the stromal beds of two corneas after FSL lamellar cuts were made.During the second phase of the study,a randomized clinical trial was conducted that included two treatment groups of patients with keratoconus:group 1(n=14 eyes) underwent FSL-assisted DALK associated with PTK and group 2(n=12 eyes) underwent FSL-assisted DALK associated with the bigbubble technique.The main outcome measures were the postoperative visual acuity(VA) and optical coherence tomography(OCT) measurements,confocal microscopic findings,and contrast sensitivity.RESULTS:In the pilot study,histopathology showed a more regular stromal bed in the FSL+PTK group.In the clinical trial,group 1 had significantly worse best spectaclecorrected VA and contrast sensitivity(P<0.05 for both comparisons).The residual stromal bed measured by OCT was significantly(P<0.05) thicker in group 1.Confocal microscopy detected opacities only at the donor-receptor interface in group 1.CONCLUSION:Patients with keratoconus treated with FSL-assisted DALK performed using the big-bubble technique fare better than treated with FSL-assisted DALK associated with PTK. | Jarbas Pereira de Macedo Lauro Augusto de Oliveira Flavio Hirai Luciene Barbosa de Sousa | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 2 |
| 4 | Fractalkine: multiple strategies to counteract glutamate receptors activation leading to neuroprotection显示文摘Glutamate(Glu)is the main excitatory amino acid in the brain and plays a pivotal role in many neurophysiological functions.Nevertheless,an excess and prolonged exposure to Glu determines the overactivation of glutamate receptors(Glu Rs)with consequent impairment of cellular calcium(Ca2+)homeostasis,leading to the dysregulation of intracellular pathways and resulting in neuronal dysfunction | Clotilde Lauro | 2015 | Neural Regeneration Research2015，10，8： | 2 |
| 5 | Liver Transplantation for Hepatocellular Carcinoma Under Calcineurin Inhibitors: Reassessment of Risk Factors for Tumor Recurrence显示文摘 | Marco Vivarelli Alessandro Cucchetti Giuliano La Barba Matteo Ravaioli Massimo Del Gaudio Augusto Lauro Gian Luca Grazi Antonio Daniele Pinna | 2008 | Annals of Surgery2008，，5： | 2 |
| 6 | 影响口腔种植美学效果的因素:生物学 临床 手术及修复方面显示文摘目的分析影响口腔种植美学效果的因素,评价不需要黏膜切开及翻瓣的即刻种植方法对种植成功及美学效果的影响。方法55例患者接受即刻种植手术,共种植87枚种植体,术后3个月行临时冠修复,4个月后行永久修复。术后2年内行定期临床及影像学检查。结果脱落3枚种植体,即刻种植成功率96.6%,失败率3.4%。结论不切开黏膜及翻瓣的即刻种植方法,能够保留更多的种植区软、硬组织,确保种植体周围组织愈合。唇颊侧骨壁的高度和厚度是影响种植美学效果的最重要因素。 | Gilberto Sammartino Gaetano Marenzi Alessandro Espedito di Lauro 张翀 邓春富 | 2008 | 中国实用口腔科杂志2008，1，2： | 2 |
| 7 | Acidic heteroxylans from medicinal plants and their anti-ulcer activity显示文摘 | Thales R. Cipriani Caroline G. Mellinger Lauro M. de Souza Cristiane H. Baggio Cristina S. Freitas Maria C.A. Marques Philip A.J. Gorin Guilherme L. Sassaki Marcello Iacomini | 2008 | Carbohydrate Polymers2008，，2： | 2 |
| 8 | Surgeon's perspective on short bowel syndrome: Where are we?显示文摘Short bowel syndrome(SBS) is due to a massive loss of small bowel: the reduction of gut function is below the minimum necessary to maintain health(in adults) and growth(in children) so intravenous supplementation is required. Parenteral nutrition represents the milestone of treatment and surgical attempts should be limited only when the residual bowel is sufficient to increase absorption, reducing diarrhea and slowing the transit time of nutrients, water and electrolytes. The surgical techniques lengthen the bowel(tapering it) or reverse a segment of it: developed in children, nowadays are popular also among adults. The issue is mainly represented by the residual length of the small bowel where ileum has shown increased adaptive function than jejunum, but colon should be considered because of its importance in the digestive process. These concepts have been translated also in intestinal transplantation, where a colonic graft is nowadays widely used and the terminal ileum is the selected segment for a livingrelated donation. The whole replacement by a bowel or multivisceral transplant is still affected by poor long term outcome and must be reserved to a select population of SBS patients, affected by intestinal failure associated with irreversible complications of parenteral nutrition. | Ignazio R Marino Augusto Lauro | 2018 | World Journal of Transplantation2018，8，6： | 2 |
| 9 | α-Amylolysis of large barley starch granules显示文摘 | Lauro M Forssol P M Suortti M T | 1992 | Cereal Chemistry1992，76，6： | 1 |
| 10 | The genome sequence of the psychrophilic archaeon, Methanococcoides burtonii: the role of genome evolution in cold adaptation显示文摘 | Allen M A Lauro F M Williams T J | 2009 | ISME J2009，3，9： | 1 |
| 11 | PLS Path Model- ing显示文摘 | Tenenhaus M Vinzi V.E Chatelin Y.M Lauro C | | 0，，01： | 1 |
| 12 | A unique combination of transcription factors controls differentiation of thyroid cells显示文摘 | Damante G Tell G Di Lauro R | 2001 | Progress Nucleic Acid Res Mol Biol2001，66，： | 1 |
| 13 | Incidence and management of abdominal closure-related complications in adult intestinal transplantation显示文摘 | Zanfi C Cescon M Lauro A | 2008 | Transplantation2008，85，11： | 1 |
| 14 | Monocyte chemotac-tic protein-3 induces human coronary smooth muscle cell proliferation显示文摘 | Maddaluno M Di Lauro M Di Pascale A | 2011 | Atherosclerosis2011，217，1： | 1 |
| 15 | Effects of Fungal Laccase Immobilization Procedures for the Development of a Biosensor for Phenol Compounds显示文摘 | Renato S Freire Nelson Dura′n Lauro T | 2001 | Talanta2001，，54： | 1 |
| 16 | The microstructure,thermal fatigue,and failure analysis of near-ternary eutectic Sn-Ag-Cu solder joints显示文摘 | KANG S K LAURO P SHIH D Y | | 0，，3： | 1 |
| 17 | Idiom Comprehen- sion: A Prefrontal Task? 显示文摘 | Lauro L J R Tettamanti M Cappa S | 2008 | Cerebral Cortext2008，，18： | 1 |
| 18 | Effect of flavonoids on the Ap(25-35)-phospholipid bilayers interaction显示文摘 | Tedeschi A D'Errico G Lauro MR | 2010 | Eur J Med Chem2010，45，9： | 1 |
| 19 | Thyroid development and its disorders:genetics and molecular mechanisms显示文摘 | DE FELICE M DI LAURO R | 2004 | Endocr Rev2004，25，： | 1 |
| 20 | Photoinactivation ofbacterial strains involved in periodontal diseases sensitized byporphycene polylysine conjugates显示文摘 | Lauro FM Pretto P Covolo L | 2002 | Photochemistry andPhotobiology Sciences2002，1，7： | 1 |
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