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12篇 您的检索式:作者名="Langsford"
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1Dysglycemia after renal transplantation:Definition,pathogenesis,outcomes and implications for management显示文摘New-onset diabetes after transplantation(NODAT) is major complication following renal transplantation. It commonly develops within 3-6 mo post-transplantation. The development of NODAT is associated with significant increase in risk of major cardiovascular events and cardiovascular death. Other dysglycemic states, such as impaired glucose tolerance are also associatedwith increasing risk of cardiovascular events. The pathogenesis of these dysglycemic states is complex. Older recipient age is a consistent major risk factor and the impact of calcineurin inhibitors and glucocorticoids has been well described. Glucocorticoids likely cause insulin resistance and calcineurin inhibitors likely cause β-cell toxicity. The impact of transplantation in incretin hormones remains to be clarified. The oral glucose tolerance test remains the best diagnostic test but other tests may be validated as screening tests. Possibly, NODAT can be prevented by administering insulin early in patients identified as high risk for NODAT. Once NODAT has been diagnosed altering immunosuppression may be acceptable, but creates the difficulty of balancing immunological with metabolic risk. With regard to hypoglycemic use, metformin may be the best option. Further research is needed to better understand the pathogenesis, identify high risk patients and to improve management options given the significant increased risk of major cardiovascular events and death.David Langsford Karen Dwyer 2015World Journal of Diabetes2015,6,10:6
2Effects of diagenesis on enhanced-resolution bulk density logs in Tertiary Gulf Coast sandstones:an example from the Lower Vicksburg Formation,McAllen Ranch field,south Texas显示文摘Grigsby J D Langsford R P 0,,11:1
3Effcets of diagenesis on enhanced- resolution bulk density logs in Tertiary Gulf Coast sandstones:An example form the Lower Vicksburg Formation, McAllen Ranch field, South Texas显示文摘Grigsby J D Langsford R P 1996AAPG Bulletin1996,80,11:1
4Effects of diagenesis on en-hanced-resolution bulk density logs in Tertiary Gulf Coast sandstones:An example from the Lower Vicksburg Forma-tion,McAllen Ranch field,south Texas显示文摘Grigsby J D Langsford R P 1996AAPG Bulletin1996,80,11:1
5Adoptive T cell immunotherapy for treatment of ganciclovir-resistant cy- tomegalovirus disease in a renal transplant recipient 显示文摘MACESIC N LANGSFORD D NICHOLLS K 2015Am J Transplant2015,15,3:1
6Effects of diagenesis on enhanced-resolution bulk density logs in Tertiary Gulf Coast sandstones: an example from the Lower Vicksburg Formation, McAllen Ranch field, south Texas显示文摘Grigsby J D Langsford R P 1996AAPG Bulletin1996,80,11:1
7Coping and psychological distress in children involved in road acci dents显示文摘Stellard P Velleman R Langsford J 2001Br J Clin Psychol2001,40,:1
8Measurement of ane- choic chanber reflections by time-domain techniques 显示文摘Clouston E N Langsford P A Evans S 1988IEEE PROCEEDINGS1988,135,2:1
9Coping and psychological distress in children involved in road traffic accidents显示文摘Stallard P Velleman R Langsford J 2001Br J C/in Psycho/2001,40,2:1
10Coping and pasy chlological distress in children involved in road traffic ac cidents显示文摘Stallard P Velleman R Langsford J 2001British Jouranl of Clinical Psychology2001,40,:1
11Effects of diagenesis on enhanced resolution bulk density logs in Tertiary Gulf Coast sand stones:An example from the Lower Vicksburg Formation , McAllen Ranch field, south Texas显示文摘Grigsby J D Langsford R P 1996AAPG Bulletin1996,80,11:1
12Adoptive T cell immu- notherapy for treatment of ganciclovir-resistant cytomegalov- irus disease in a renal transplant recipient显示文摘Naeesie N Langsford D Nicholls K 2015Am J Transplant2015,15,3:1
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