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| 1 | 18F-氟脱氧葡萄糖的摄取作为原发性宫颈癌放疗后的预后指标显示文摘Purpose. We evaluated the prognostic significance of tumor metabolic activity on pretreatment positron emission tomography using the glucose analog F- 18 fluorodeoxyglucose (FDG- PET) in patients with carcinoma of the cervix undergoing radiotherapy with or without concurrent chemotherapy. Methods. We studied 96 consecutive patients who underwent FDG- PET prior to initiation of radiotherapy with or without concurrent chemotherapy for carcinoma of the cervix. Pretreatment FDG uptake of the primary tumor was assessed with the semiquantitative standardized uptake value (SUV) and correlated with di-sease- free and overall survival. Survival was estimated by the Kaplan- Meier method. Univariate and multivariate analyses were performed with the logistic likelihood ratio test and the Cox proportional hazards model, respectively. Results. Five-year disease- free survivals in patients with maximal SUV < 10.2 and ≥ 10.2 were 71% and 52% (P = 0.0289)- respectively, while overall survivals were 72% and 69% (P = 0.4), respectively. On multivariate analysis, lymph node metastasis on FDG- PET was found to be predictive of disease- free survival (P < 0.0001). Both the SUV for FDG and FIGO Stage I disease were found to be marginally predictive of disease- free survival (P = 0.055 and P = 0.058, respectively). Conclusions. FDG uptake within primary cervical cancer, as measured by SUV, is predictive of disease- free survival in patients undergoing radiotherapy for cervical cancer. High FDG uptake may be useful in identifying patients who may require more aggressive initial therapy. | Dehdashti F. P.W. Grigsby 李奎 | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，2，9： | 2 |
| 2 | Cervix carcinoma,concurrent chemoradiotherapy,and salvage of isolated paraaortic lymph node recurrence显示文摘 | Singh AK Grigsby PW Rader JS | 2005 | Int J Radiat Oncol Biol Phys2005，61，2： | 1 |
| 3 | Childhood and adolescent thyroid carcinoma 显示文摘 | Grigsby PW Gal-or A Michalski JM | 2002 | Cancer2002，95，4： | 1 |
| 4 | Radiation therapy morbidity in carcinoma of the uterine cervix: Dosimetric and clinical correlation显示文摘 | PEREZ C A GRIGSBY P W LOCKETr M A | 1999 | Int J Radiat Oncol Biol Phys1999，44，4： | 1 |
| 5 | PET-guided IMRT for cervical carcinoma with positive para-aortic lymph nodes-a dose-escalation treatment planning study 显示文摘 | Mutic S Malyapa RS Grigsby PW | 2003 | International Journal of Radiation Oncology Bioliogu Physics2003，55，1： | 1 |
| 6 | 2ntensity-modulated radiation therapy (IMRT) reduces small bowel, rectum, and bladder doses in patients with cervical cancer receiving pelvic and para-aortic irradiation显示文摘 | Portelance L Chao KS Grigsby PW | 2001 | 2nt J Radiat Oncol Biol Phys2001，51，1： | 1 |
| 7 | Regional expression of prostaglandin E2 and F2 α receptors in human myometrium, amnion, and choriodecidua with advancing gestation and labor 显示文摘 | Grigsby PL Sooranna SR Adu-Amankwa B | 2006 | Biol Reprod2006，75，2： | 1 |
| 8 | Radiation therapy for carcinoma of the cervix with biopsy-proven positive para-aortic lymph nodes显示文摘 | Grigsby PW Perez CA Chao KS | 2001 | Int J Radiat Oncol Biol Phys2001，49，3： | 1 |
| 9 | Intensity-modula- ted radiation therapy (IMRT) reduces small bowel, rec- tum, and bladder doses in patients with cervical cancer re- ceiving pelvic and para-aortic irradiation 显示文摘 | Portelance L Chao KS Grigsby PW | 2001 | Int J Radiat Oncol Biol Phys2001，51，1： | 1 |
| 10 | Intensity-modulated radiation therapy(IMRT)reduces small bowel,rectum,and bladder doses in patients with cervical cancer receiving pelvic and para-aortic irradiation显示文摘 | Portalance L Chao KS Grigsby PW | 2001 | Int J Radiat Oncol Biol Phys2001，51，1： | 1 |
| 11 | Assessing tumor hypoxia in cervical cancer by positron emission tomography with 60Cu-ATSM:relationship to therapeutic response-a preliminary report显示文摘 | Dehdashti F Grigsby P W Mintun MA | 2003 | Int J Radiat Oncol Biol Phys2003，55，5： | 1 |
| 12 | Comparison of molecular markers of hypoxia and Imaging with (60) Cu-ATSM in cancer of the uterine cervix 显示文摘 | Grigsby PW Malyapa RS Higashikubo R | 2007 | Mol Imaging Biol2007，13，： | 1 |
| 13 | Tumor volume discrepancies between FDG-PET and MRI for cervical cancer显示文摘 | Ma DJ Zhu JM Grigsby PW | 2011 | Radiother Oncol2011，98，1： | 1 |
| 14 | Effects of diagenesis on enhanced-resolution bulk density logs in Tertiary Gulf Coast sandstones:an example from the Lower Vicksburg Formation,McAllen Ranch field,south Texas显示文摘 | Grigsby J D Langsford R P | | 0，，11： | 1 |
| 15 | PET guided IMRT for cervical carcinoma with positive para-aortic lymphnodes: A dose-escalation treatment planning study显示文摘 | Mutic S Malyapa RS Grigsby PW | 2003 | Int J Radiat Oncol Biol Phys2003，55，1： | 1 |
| 16 | Quartz dissolution kine- tics from 100-200C as a function of pH and ionic strength显示文摘 | Worley W G Tester J W Grigsby C O | 1996 | AICHE J1996，42，12： | 1 |
| 17 | Prevalence of anxiety in adults with diabetes: a systematic review 显示文摘 | Grigsby AB Anderson RJ Freedland KE | 2002 | J Psycbesom Res2002，53，6： | 1 |
| 18 | Evaluation oflatex adhesives containing hydrophobic cores and poly(vinyl acetate)shells: potential to improve poly (vinyl acetate)performance 显示文摘 | Grigsby W J Ferguson C J Franich R A | 2005 | International Journal of Adhesion andAdhesives2005，25，2： | 1 |
| 19 | Modification of the radiation respons of patients with carcinoma of the uterine cervix显示文摘 | | 1999 | Cancer Control1999，6，： | 1 |
| 20 | Postoperative vaginal brachytherapy alone is the treatment of choice for grade 1-2,stage Ⅰ C endometrial cancer显示文摘 | Cengiz M Singh AK Grigsby PW | 2005 | Int J Gynecol Cancer2005，15，： | 1 |
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