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3篇 您的检索式:作者名="Lanfeng LIN"
    题名 作者 年代 出处 被引量
1High Jc Epitaxial Superconducting YBa_2Cu_3O_(7-x) Thin Films显示文摘Excellent epitaxial growth of supercon-ducting YBa2 Cu3 O7-x thin films have beenrealized on(100)SrTiO3 and(100)ZrO2substrates by a planar rf or DC-magnetronsputtering apparatus with UHV system.Thequality of growth and the epitaxial orientationof the film strongly depended on substratetemperature,the substrate orientation and ox-ygen partial pressure.The films exhibitedsuperconducting onset at 92K and zero resist-ance at 90K with critical current densityChen Lanfeng Zhou Li Wang Chaoqun General Research Institute of Non-ferrous Metals.Beijing,China Li Lin Zhao Bairu Zhang Yinzi Qiu Xianggang Institute of Physics,Academia Sinica,Beijing.China Pang Shijing Beijing Laboratory of Vacuum Physics,China Kou Yuanheng Department of Physics.Peking University,Beijing,China 1990Rare Metals1990,10,1:0
2A human monoclonal antibody neutralizes SARS-CoV-2 Omicron variants bytargeting the upstream region of spikeprotein HR2 motif显示文摘The continuous emergence of new severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)variants meansthere is a need to explore additional strategies to develop broad-spectrum vaccines or therapeutics for individuals remaining at risk of coronavirus disease 2019(COVID-19).Neutralizing monoclonal antibody(mAb)that binds to theconserved S2 subunit of the SARS-CoV-2 spike(S)protein alone,or in combination with mAb that binds to the receptor-binding domain(RBD)of S protein,might be effective in eliciting protection from infection by a variety of SARS-CoV2 variants.Using high-throughput single-cell immunoglobulin sequencing of B cells from COVID-19-convalescent donors,we identified a high-affinity S2-specific mAb-39,that could inhibit original SARS-CoV-2 strain,Omicron BA.1,BA.2.86,BA.4,BA.5,and EG.5.1 S protein-mediated membrane fusion,leading to the neutralization of these pseudoviralinfections.Moreover,mAb-39 could also improve the neutralizing activity of anti-RBD antibody against the highlyneutralization-resistant Omicron variants.Molecular docking and point mutation analyses revealed that mAb-39 recognized epitopes within the conserved upstream region of the heptad repeat 2(HR2)motif of the S2 subunit.Collectively,these findings demonstrate that targeting the conserved upstream region of the HR2 motif(e.g.,using mAbs)provides anovel strategy for preventing the infection of SARS-CoV-2 and its variants.Hang Su Jun Zhang Zhenfei Yi Sajid Khan Mian Peng Liang Ye Alan Bao Han Zhang Guangli Suo Qian Li Housheng Zheng Dandan Wu Thomas J.Kipps Lanfeng Wang Zhenghong Lin Suping Zhang 2024hLife2024,2,3:0
3A 17–26.5 GHz 42.5 dBm broadband and highly efficient gallium nitride power amplifier design显示文摘A gallium nitride(GaN)power amplifier monolithic microwave integrated circuit(MMIC)with a wide band and high efficiency in the microwave frequency band is proposed in this study.The power amplifier MMIC uses a 0.15^im GaN high electron mo-bility transistor(HEMT)process.The operating frequency band of the amplifier can cover the whole K-band,i.e.,17-26.5 GHz.Ming LI Zhiqun LI Quan ZHENG Lanfeng LIN Hongqi TAO 2022Frontiers of Information Technology & Electronic Engineering2022,23,2:0
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