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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community based study显示文摘 | Nieto F J Young TB Lind BK Shahar E Samet JM Redline S D’ Agostino RB Newman AB Lebowitz MD Picketing TG | 2000 | JAMA2000，283，： | 1 |
| 3 | Tensile and compressive properties of cancellous bone 显示文摘 | Rohl L Larsen E Linde F | 1991 | J Biomech1991，24，： | 1 |
| 4 | The in vi- vo function of a noncanonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiation显示文摘 | LU L F AHONEN C L LIND E F | 2007 | Blood2007，110，： | 1 |
| 5 | Fixation of displaced femoral neck fractures 显示文摘 | Madsen F Linde F Anecerson E | 1987 | Acta Orthop Scand1987，，58： | 1 |
| 6 | The MACH 2 study: role of omeprazole in eradication of Helicobacter pylori with 1-week triple therapies显示文摘 | Lind T Megraud F Unge P Bayerdorffer E OMOrain C Spiller C | 1999 | Gastroenterology1999，116，2： | 1 |
| 7 | Hxation of displaced femoral neck fractures A comparison between sliding screw plate and four cancellous bone screws显示文摘 | Madsen F Linde F Andersen E et at | | 0，，03： | 1 |
| 8 | Hydrogen-What are the cost显示文摘 | STOLL R E von LINDE F | 2000 | Hydrocarbon Process2000，79，12： | 1 |
| 9 | The role of oxygen in camphorquinone-initiated photopolymerizationl显示文摘 | Andrzejewska E Lindén L A Rabek J F | 1998 | Macromo Chem Commun1998，119，： | 1 |
| 10 | Mast cells are essential intermediaries in regulatory T-cell tolerance显示文摘 | Lu L F Lind E F Gondek D C | 2006 | Nature2006，442，7106： | 1 |
| 11 | The in vivo function of a non- canonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiation 显示文摘 | Lu L F Ahonen C L Lind E F | 2007 | Blood2007，110，1： | 1 |
| 12 | Fatal interstitial lung disease after erlotinib for non-small cell lung cancer 显示文摘 | Lind J S Smit E F Grunberg K | 2008 | J Thorac Oncol2008，3，9： | 1 |
| 13 | Effect of low-density lipoprotein cholesterol on angiotensin Ⅱ sensitivity : a randomized trial with fluvastatin 显示文摘 | Van der Linde NA Sijbrands E J Boomsma F | 2006 | Hypertension2006，47，6： | 1 |
| 14 | Hydrogen-what are the cost显示文摘 | Stoll R E von Linde F | 2000 | Hydrocarbon Process2000，79，12： | 1 |
| 15 | Phase I study of concurrent whole brain radiotherapy and erlotin- ib for multiple brain metastases from non - small - cell lung cancer 显示文摘 | Lind J S Lagerwaard F J Smit E F | 2009 | Int J Radiat Oncol Biol Phys2009，74，5： | 1 |
| 16 | Nonscarring inflammatory alopeeia associated with the epidermal growth factor receptor inhibitor gefitinib显示文摘 | Graves J E Jones B F Lind A C et a l | 2006 | J Am Acad Dermatol2006，55，2： | 1 |
| 17 | No postpran- dial increase of plasma adiponectin in obese subjects 显示文摘 | KARLSSON F A ENGSTROM B E LIND L | 2004 | Obes Res2004，12，6： | 1 |
| 18 | Mast cells are essential intermediaries in regulatory T cell tolerance显示文摘 | LU L F Lind E F Gondek D C | 2006 | Nature2006，442，7106： | 1 |
| 19 | Mast cells are essential intermediaries in regulatory- T cell tolerance显示文摘 | Lu L F Lind E F Gondek D C | 2006 | Nature2006，442，： | 1 |
| 20 | A holistic approach to the integration of safety applications:The INSAFES subproject within the European framework programmne 6 integrating project PReVENT显示文摘 | AMDITIS A BERTOLAZZI E BIMPAS M BIRAL F BOSETTI P LIO D M DANIELSSON L GALLIONE A LIND H SAROLDI A SJOGREN A | | 0，，03： | 1 |
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