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| 1 | Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer显示文摘AIM To determine the frequency and risk factors for colorectal cancer(CRC) development among individuals with resected advanced adenoma(AA)/traditional serrated adenoma(TSA)/advanced sessile serrated adenoma(ASSA). METHODS Data was collected from medical records of 14663 subjects found to have AA, TSA, or ASSA at screening or surveillance colonoscopy. Patients with inflammatory bowel disease or known genetic predisposition for CRC were excluded from the study. Factors associated with CRC developing after endoscopic management of high risk polyps were calculated in 4610 such patients who had at least one surveillance colonoscopy within 10 years following the original polypectomy of the incident advanced polyp. RESULTS84/4610(1.8%) patients developed CRC at the polypectomy site within a median of 4.2 years(mean 4.89 years), and 1.2%(54/4610) developed CRC in a region distinct from the AA/TSA/ASSA resection site within a median of 5.1 years(mean 6.67 years). Approximately, 30%(25/84) of patients who developed CRC at the AA/TSA/ASSA site and 27.8%(15/54) of patients who developed CRC at another site had colonoscopy at recommended surveillance intervals. Increasing age; polyp size; male sex; right-sided location; high degree of dysplasia; higher number of polyps resected; and piecemeal removal were associated with an increased risk for CRC developmentat the same site as the index polyp. Increasing age; right-sided location; higher number of polyps resected and sessile endoscopic appearance of the index AA/TSA/ASSA were significantly associated with an increased risk for CRC development at a different site. CONCLUSION Recognition that CRC may develop following AA/TSA/ASSA removal is one step toward improving our practice efficiency and preventing a portion of CRC related morbidity and mortality. | Mohamad A Mouchli Lidia Ouk Marianne R Scheitel Alisha P Chaudhry Donna Felmlee-Devine Diane E Grill Shahrooz Rashtak Panwen Wang Junwen Wang Rajeev Chaudhry Thomas C Smyrk Ann L Oberg Brooke R Druliner Lisa A Boardman | 2018 | World Journal of Gastroenterology2018，24，8： | 5 |
| 2 | A high-density, multi-parental SNP genetic map on apple validates a new mapping approach for outcrossing species显示文摘Quantitative trait loci(QTL)mapping approaches rely on the correct ordering of molecular markers along the chromosomes,which can be obtained from genetic linkage maps or a reference genome sequence.For apple(Malus domestica Borkh),the genome sequence v1 and v2 could not meet this need;therefore,a novel approach was devised to develop a dense genetic linkage map,providing the most reliable marker-loci order for the highest possible number of markers.The approach was based on four strategies:(i)the use of multiple full-sib families,(ii)the reduction of missing information through the use of HaploBlocks and alternative calling procedures for single-nucleotide polymorphism(SNP)markers,(iii)the construction of a single backcross-type data set including all families,and(iv)a two-step map generation procedure based on the sequential inclusion of markers.The map comprises 15417 SNP markers,clustered in 3 K HaploBlock markers spanning 1267 cM,with an average distance between adjacent markers of 0.37 cM and a maximum distance of 3.29 cM.Moreover,chromosome 5 was oriented according to its homoeologous chromosome 10.This map was useful to improve the apple genome sequence,design the Axiom Apple 480 K SNP array and perform multifamily-based QTL studies.Its collinearity with the genome sequences v1 and v3 are reported.To our knowledge,this is the shortest published SNP map in apple,while including the largest number of markers,families and individuals.This result validates our methodology,proving its value for the construction of integrated linkage maps for any outbreeding species. | Erica A Di Pierro Luca Gianfranceschi Mario Di Guardo Herma JJ Koehorst-van Putten Johannes W Kruisselbrink Sara Longhi Michela Troggio Luca Bianco Hélène Muranty Giulia Pagliarani Stefano Tartarini Thomas Letschka Lidia Lozano Luis Larisa Garkava-Gustavsson Diego Micheletti Marco CAM Bink Roeland E Voorrips Ebrahimi Aziz Riccardo Velasco François Laurens W Eric van de Weg | 2016 | Horticulture Research2016，3，1： | 3 |
| 3 | Effect of n ? 3 HUFA level in broodstock diets on egg quality of gilthead sea bream ( Sparus aurata L.)显示文摘 | Hipólito Fernández-Palacios María Soledad Izquierdo Lidia Robaina Antonio Valencia María Salhi JoséM. Vergara | 1995 | Aquaculture1995，，3： | 2 |
| 4 | Biodegradable polyesters reinforced with surface-modified vegetable fibers 显示文摘 | Elisa Z Massimo B Lidia A | 2004 | Macromolecular Bioseience2004，，4： | 1 |
| 5 | Mandarin peel wastespretreatment with steam explosion for bioethanol production显示文摘 | MARIA B A LIDIA G V FAYINY P G C | 2010 | Bioresource Technology2010，101，10： | 1 |
| 6 | G-protein-poupled receptor 30 and estrogen receptor-a are involved in the proliferative effects induced by atrazine in ovarian cancer ceils 显示文摘 | Lidia A Rosamaria L Antonio M | 2008 | Environ Health Perspect2008，116，12： | 1 |
| 7 | U-shaped slope gully systems and sediment waves on the passive margin of Gabon (West Africa) 显示文摘 | LIDIA L NUR H J CHRISTOPHER A L | 2013 | Marine Geology2013，，337： | 1 |
| 8 | Characterization of elemental and polycyclic aromatic hydrocarbon compositions of urban air in Brisbane显示文摘 | McKenzie C H Lim Godwin A Ayoko Lidia Morawska | 2005 | Atmospheric Environment2005，39，： | 1 |
| 9 | Fingerprinting of mixed bacterial strains and BIOLOG gram-negative (GN) substrate communities by enterobacterial repeti- tive intergenic consensus sequence-PCR (ERIC-PCR)显示文摘 | George D Giovanni D Lidia S a/ | 1999 | Current Microbiology1999，38，4： | 1 |
| 10 | Changes in manganese superoxide dismutase expression after exposure of the retina to intense light 显示文摘 | Yamamoto M Lidia K Gong H Onitsuka S Kotani T Ohira A | 1999 | Histochem J1999，31，2： | 1 |
| 11 | Histone deacetylase inhibitors: mechanism of action and therapeutic use in cancer显示文摘 | Olaia Martínez-Iglesias Lidia Ruiz-Llorente Ruth Sánchez-Martínez Laura García Alberto Zambrano Ana Aranda | | 0，2008，： | 1 |
| 12 | Inhibitors of human histone deacetylase:synthesis and enzyme and cellular activity of straight chain hydroxamates显示文摘 | Stacy WR Lidia CS Peter A | 2002 | J Med Chem2002，45，4： | 1 |
| 13 | Effect of Ginkgo biloba extract EGb 761 on the nonspecific and humoral immune responses in a hypothalamic–pituitary–adrenal axis activation model显示文摘 | Mar??a Martha Villase?or-Garc??a Xavier Lozoya Lidia Osuna-Torres Juan Manuel Viveros-Paredes Lucila Sandoval-Ram??rez Ana Mar??a Puebla-Pérez | 2004 | International Immunopharmacology2004，，9： | 1 |
| 14 | RecruitingHighly Educated Graduates:A Study on the Relationship BetweenRecruitment Information Sources,the Theory of Planned Behav-ior,and Actual Job Pursuit显示文摘 | Yasmina Jaidi Edwin A J Van Hooft Lidia R Arends | 2011 | Human Performance2011，24，： | 1 |
| 15 | Recent trends on nanocomposites based on Cu, Ag and Au clusters: A closer look 显示文摘 | Lidia A Davide B Gregorlo B | 2006 | Coordination Chemistry Reviews2006，250，1112： | 1 |
| 16 | Luminescent prop-erties of Eu - doped lanthanum oxyfl uoride Sol Gel thin films 显示文摘 | Lidia A Gregorio B Laura B | 2009 | J Phys Chem C2009，113，14： | 1 |
| 17 | Histone deacetylase inhibitors: mechanism of action and therapeutic use in cancer显示文摘 | Olaia Martínez-Iglesias Lidia Ruiz-Llorente Ruth Sánchez-Martínez Laura García Alberto Zambrano Ana Aranda | 2008 | Clinical and Translational Oncology2008，，7： | 1 |
| 18 | Human papillomavirus type 16 molecular variants in Guarani Indian women from Misiones, Argentina显示文摘 | Sergio Andrés Tonon Jorge Basiletti Ines Badano Lidia Virginia Alonio Luisa Lina Villa Angélica Rita Teyssie María Alejandra Picconi | 2006 | International Journal of Infectious Diseases2006，，： | 1 |
| 19 | Bis-chelated palladium(II) complexes with nitrogen-donor chelating ]igands 显示文摘 | Barbara M Anna A Lidia V | 1997 | Organometallies1997，16，23： | 1 |
| 20 | Length of optimal path in random networks with strong disorder显示文摘 | Sergey V Buldyrev Lidia A Braunstein Reuven Cohen | 2003 | Physica A2003，330，2： | 1 |
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