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| 1 | A model for coupling reservoir inflow and wellbore flow in fishbone wells显示文摘A coupling model is proposed in this paper by using the Green Function and Newman's product principle, and the solution method is provided here as well. This model can be used to describe the reservoir inflow and wellbore flow for fishbone wells in an unsteady flow or pseudo-steady flow state. A case study indicates that the bottom hole pressure declines quickly in the unsteady flow period which is very short. The pressure drop per unit time remains unchanged under the pseudo-steady flow conditions. The distribution of flow rate along the main wellbore shows a wave shape under the unsteady flow condition, and the flow rate distribution in each branch is similar. The flow rate distribution along the main wellbore is irregular 'U' shaped under the pseudo-steady flow condition, and the space-symmetrical branches have the same flow distribution pattern. In the initial production period, the flow rate increases significantly as the length of branches and the angle between branches and the main wellbore increase. As the production continues, the length and angle of branches have only a slight effect on the flow in fishbone wells. | Lian Peiqing Cheng Linsong Tan Xuequn Li Linlin | 2012 | Petroleum Science2012，9，3： | 4 |
| 2 | EGFR signaling augments TLR4 cell surface expression and function in macrophages via regulation of Rab5a activation显示文摘Dear Editor,oll-like receptor 4(TLR4)is a key receptor sensing bacterial lipopolysaccharide(LPS),and is the most investigated member of the Tol-like receptor family(Kawai and Akira,2007;Kayagaki et al,2013;Klein et al.,2015).Cell surface TLR4 expression is determined by the balance between receptor trafficking from the Golgi apparatus to the cell membrane,and internalization of the cell surface receptor into endosomal compartments(Saltoh,2009).In bone mar-row-derived macrophages(BMDM),we observed LPS-in-duced EGFR phosphorylation on the surface of BMDM,and this was inhibited by pretreatment with PD168393 or TAPI-1(Fig.S1).Next,we measured dynamic changes in cell sur-face TLR4 expression after LPS treatment.At6,12,and 24 h after LPS treatment,TLR4 expression on the surface of BMDM was increased^2-,~6-,and^9-fold,respectively,as compared with controls. | Jing Tang Bowei Zhou Melanie JScott Linsong Chen Dengming Lai Erica KFan Yuehua Li Qiang Wu Timothy RBilliar Mark AWilson Ping Wang Jie Fan | 2020 | Protein & Cell2020，11，2： | 2 |
| 3 | High quality ZnSe and ZnS nanocrystals formed by activating zinc carboxylate precurs ors显示文摘 | Li Linsong Narayan Pradhan Wang Yunjun | 2004 | Nano Letters2004，4，11： | 1 |
| 4 | Genesis of Kaolinite Deposits in the Jungar Coalfield,North China:Petrological,Mineralogical and Geochemical Evidence显示文摘Petrological,mineralogical and geochemical studies carried out on kaolinite deposits in Haerwusu surface mine,Jungar Coalfield,northern Ordos Basin,North China,define their characteristics,ore genesis and economic interest.Based on the crystalline size,two different types of kaolinite rocks,cryptocrystalline and grainy,were identified under the microscope.XRD data show that kaolinite is the predominant mineral,associated with boehmite,magnesite,anatase,pyrite,diaspore and calcite.However,high boehmite content(mean 70%)shows up in the middle layers.Kaolinite minerals present homogeneous shape and a good crystallinity(HI=0.96–1.26).Geochemical studies show that the SiO_(2)/Al_(2)O_(3)molar ratio of kaolinite is close to the theoretical value,and the contents of Na_(2)O,K_(2)O,CaO,Mg O are less,suggesting a strong chemical weathering environment.The REE and Eu anomalies show a close relationship between kaolinite and the Yinshan Oldland granite.A Ce anomaly reflects a continental sedimentary environment with shallow water.A temperature range of 26.7–34℃was calculated on the basis of the isotopic signatures(δ18O,δD)of the kaolinite rocks.All these data indicate that the formation of the kaolinite is caused mainly by the dissolution,coagulation,precipitation and recrystallization of aluminosilicate clastics in acidic conditions.The formation of boehmite in the middle layers indicates that the source rocks have changed.Boehmite is mainly formed by dehydration and compaction of an aluminum-rich colloid which transported into peat swamp during diagenesis.In addition,it formed by desiliconization of kaolinite under acidic conditions.Due to its high kaolinite content(up to 90%)and low iron mineral content(less than 1%),and good crystallinity,kaolinite deposits occurred at Haerwusu surface mine probably have great economical value in the future. | LIU Linsong ZHANG Tongjun LIU Jianping LIU Qinfu LI Kuo LIU Di LIU Wanyue | 2021 | Acta Geologica Sinica(English Edition)2021，95，2： | 1 |
| 5 | Lowvelocity non-linear flow in ultra-low permeabilityreservoir 显示文摘 | ZENG Baoquan CHENG Linsong LI Chunlan | 2011 | Journal of Petroleum Science andEngineering2011，80，1： | 1 |
| 6 | High quality ZnSe and ZnS nanocrystals formed by activating zinc carboxylate precursors 显示文摘 | Li Linsong Narayan Pradhan Wang Yunjun | 2004 | Nano Letters2004，4，11： | 1 |
| 7 | Low velocity non-linear flow in ul-tra-low permeability reservoir显示文摘 | Baoquan Zeng Linsong Cheng Chunlan Li | | 0，，01： | 1 |
| 8 | Bright, Multicoloured Light-Emitting Diodes Based on Quantum Dots 显示文摘 | SUN Qingjiang Wang Y A LI Linsong | 2007 | Nature Photonics2007，1，12： | 1 |
| 9 | Qualitative and Quantitative Analysis of Iridoid Glycosides in the Flower Buds of Loniceraspecies by Capillary High Performance Liquid Chromatography Coupled with Mass Spectrometric Detector显示文摘 | SONG Yue LI Linsong WU Menghua | 2006 | Analytica Chimica Acta2006，564，： | 1 |
| 10 | Correction to:EGFR signaling augments TLR4 cell surface expression and function in macrophages via regulation of Rab5a activation显示文摘Figure 1.EGFR activation promotes TLR4 phosphorylation and cell surface expression of TLR4 in response to LPS.(A and B)BMDM were treated with LPS(1μg/mL)for 6,12,or 24 h in the presence or absence of pretreatment of PD or TAPI-1.(A)Flow cytometry analysis of cell surface TLR4 intensity in BMDM.(B)Flow cytometry analysis of cell surface TLR4 intensity in BMDM.(C and D)WT(C57BL76)mice were treated with LPS(10 mg/kg,i.p.).In some groups,mice were pretreated with erlotinib(100 mg/kg,gavage administration)at 30 min prior to LPS i.p. | Jing Tang Bowei Zhou Melanie J.Scott Linsong Chen Dengming Lai Erica K.Fan Yuehua Li Qiang Wu Timothy R.Billiar Mark A.Wilson Ping Wang Jie Fan | 2020 | Protein & Cell2020，11，8： | 0 |
| 11 | ZBTB7A governs 2-DG-inhibited glycolysis by regulating GLUT1 in nasopharyngeal carcinoma显示文摘Our previous studies suggested a potential interaction between the POK erythroid myeloid ontogenic factor ZBTB7A and glucose transporter 1(GLUT1)in nasopharyngeal carcinoma(NPC).This study was designed to confirm the interaction and further evaluate the precise mechanism by which ZBTB7A and GLUT1 regulate NPC development.The binding sites between ZBTB7A and the promoter of GLUT1 were predicted by bioinformatics.Gene expression was measured by quantitative real-time polymerase chain reaction(qPCR),western blotting,and immunohistochemistry.The activities of key glycolysis enzymes,including hexokinase(HK),pyruvate kinase(PK),lactate dehydrogenase(LDH),and lactate,were detected using specific enzyme-linked immunosorbent assay kits.The connection between ZBTB7A and GLUT1 was analyzed by dual-luciferase reporter assay and chromatin immunoprecipitation-qPCR.The vitality,proliferation,and tumorigenicity of the cells expressing different levels of ZBTB7A were tested by adding the glycolysis inhibitor 2-deoxy-D-glucose(2-DG),followed by MTT,colorimetric focus forming,and xenograft assays,respectively.Our results showed that high expression of GLUT1 was associated with late-stage NPC.After constructing stably transfected cells with lentiviruses,ZBTB7A was effectively knocked down in 5-8F cells(RNAi-5-8F)and overexpressed in 6-10B cells(ZBTB7A-6-10B).The up-or downregulation of GLUT1 secondary to ZBTB7A changes was also limited.The vitality and proliferation of the cells expressing low ZBTB7A were notably blocked by 2-DG.The cells expressing high ZBTB7A were not very sensitive to 2-DG.The growth of RNAi-5-8F xenografts was strongly suppressed by 2-DG.The activities of HK,PK,and LDH were suppressed by 2-DG in the cells expressing low ZBTB7A.RNAi-5-8F cells had the lowest 2-DG-induced lactate production.ZBTB7A directly suppressed the promoter region of GLUT1 to regulate GLUT1 expression.Thus,ZBTB7A controls the 2-DG-induced inhibition of glycolysis by affecting GLUT1. | FEI LIU JIAZHANG WEI JIAO LAN YONGLI WANG JIANXIANG YE CHENG SU MINGZHENG MO FENGZHU TANG BING LI MIN LI WEIMING DENG LINSONG YE WENLIN HUANG JINGJIN WENG WEI JIAO SHENHONG QU | 2022 | BIOCELL2022，46，12： | 0 |
| 12 | Preparation of sodium titanate nanotubes modified by CdSe quantum dots and their photovoltaic characteristics显示文摘Sodium titanate nanotubes have been prepared and modified chemically with CdSe quantum dots (QDs) using bifunctional modifiers (HS-COOH). Their photovoltaic characteristics have also been studied. The results indicate that the surface photovoltage response of nanotubes extends to the visible light region, and the intensity of surface photovoltage is enhanced after modification with CdSe QDs. The field-induced surface photovoltage spectroscopy (FISPS) shows that sodium titanate nanotubes have different photovoltaic response before and after modification. That is, the surface photovoltaic re-sponse of pure sodium titanate nanotubes increases with the enhancement of positive applied bias and decreases with the enhancement of negative applied bias. Meanwhile, the surface photovoltaic re-sponse of CdSe modified sodium titanate nanotubes is different from that of the pure sodium titanate nanotubes. The whole spectrum increases with the enhancement of applied bias at the first stage. However, when the applied bias reaches a certain value, the surface photovoltage response keeps in-creasing in some spectrum regions, while decreasing in other spectrum regions. This novel phe-nomenon is explained by using an electric field induced dipole model. | ZHANG HongMei CHENG Ke JI YanLing LIU XiaoLan LI LinSong ZHANG XingTang DU ZuLiang | 2008 | Science China Chemistry2008，51，10： | 0 |
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