|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Comprehensive and innovative techniques for livertransplantation in rats: A surgical guide显示文摘AIM: To investigate our learning curves of orthotopic liver transplantation (OLT) in rats and the most important factor for successful surgery. METHODS: We describe the surgical procedures for our rat OLT model, and determined the operator learning curves. The various factors that contributed to successful surgery were determined. The most important surgical factors were evaluated between successful and unsuccessful surgeries.RESULTS: Learning curve data indicated that 50 cases were required for operator training to start a study. Operative time, blood loss, warm ischemic time, anhepatic phase, unstable systemic hemodynamic state, and body temperature after surgery significantly affected surgery success by univariate analysis, while the anhepatic phase was the most critical factor for success by multivariate analysis. CONCLUSION: OLT in rats is the only liver transplantation model that provides clinically relevant and reliable results. Shortened anhepatic phase is key to success in this model. | Tomohide Hori Justin H Nguyen Yasuhiro Ogura Toshiyuki Hata Shintaro Yagi Ann-Marie T Baine Norifumi Ohashi Christopher B Eckman Aimee R Herdt Hiroto Egawa Yasutsugu Takada Fumitaka Oike Seisuke Saka-moto Mureo Kasahara Kohei Ogawa Koichiro Hata Taku Iida Yukihide Yonekawa Lena Sibulesky Kagemasa Kuribayashi Takuma Kato Kanako Saito Mie Torii Naruhiko Sahara Naoko Kamo Tomoko Sahara Motohiko Yasutomi Shinji Uemoto | 2010 | World Journal of Gastroenterology2010，16，25： | 14 |
| 2 | 自主神经功能检测对早期糖尿病自主神经功能损害的诊断价值显示文摘目的评价自主神经功能检测对早期糖尿病自主神经功能损害的诊断价值。方法50例2型糖尿病患者进行自主神经功能检查,即交感皮肤反应和心血管自主神经功能检测,并与30名健康人进行对比分析。结果糖尿病患者自主神经功能检测中交感皮肤反应,瓦氏比值和深呼吸时心率变异与对照组比较均有显著性差异(P<0.05),三者的异常率分别为70%,46%和50%;以交感皮肤反应的异常率最高,尤其以双下肢明显。立卧位血压差和冰水试验与对照组比较无显著性差异(P>0.05),其异常率分别为12%和16%。结论检测外周器官自主神经功能状态的方法中以交感皮肤反应的阳性率最高,可以作为检测早期糖尿病自主神经功能的常规筛选检查。 | 党静霞 Lena H Tay LB | 2006 | 西安交通大学学报(医学版)2006，27，2： | 7 |
| 3 | Treatment modalities for hypersplenism in liver transplant recipients with recurrent hepatitis C显示文摘Hepatitis C is the most common indication for orthotopic liver transplantation in the United States. Unfortunately, hepatitis C recurs universally in the transplanted liver and is the major cause of decreased graft and patient survival. The combination therapy of interferon and ribavirin has been shown to be the most effective therapy for recurrent hepatitis C. However, pre-and post-transplant hypersplenism often precludes patients from receiving the antiviral therapy. Splenectomy and partial splenic embolization are the two invasive modalities that can correct the cytopenia associated with hypersplenism. In this report we review the two treatment options, their associated outcomes and complications. | Lena Sibulesky Justin H Nguyen Ricardo Paz-Fumagalli C Burcin Taner Rolland C Dickson | 2009 | World Journal of Gastroenterology2009，15，40： | 5 |
| 4 | Cerebral venous thrombosis and heparin-induced thrombocytopenia in an 18-year old male with severe ulcerative colitis显示文摘The risk of thromboembolism is increased in inflammatory bowel disease and its symptoms may be overlooked. Furthermore, its treatment can be complex and is not without complications. We describe a case of an adolescent boy who developed a cerebral sinus venous thrombosis during a relapse of his ulcerative colitis and who, while on treatment with heparin, developed heparin-induced thrombocytopenia (HIT). The treatment was then switched to fondaparinux, a synthetic and selective inhibitor of activated factor . | Gudrun Scheving Thorsteinsson Maria Magnussson Lena M Hallberg Nils Gunnar Wahlgren Fredrik Lindgren Petter Malmborg Thomas H Casswall | 2008 | World Journal of Gastroenterology2008，14，28： | 4 |
| 5 | The cardiovascular health of residents in selected metropolitan cities in China显示文摘 | Frank H Fu Lena Fung | 2003 | Preventive Medicine2003，，4： | 1 |
| 6 | Development of NADPH-diaphorase expression in chemosensory systems of the opossum Monodelphis domestic显示文摘 | Lena SS Mimi H | 1998 | Developmental Brain Res1998，111，1： | 1 |
| 7 | A10Be-based reconstruction of the last deglaciation in southern Sweden显示文摘 | Johanna A Nicolaj K L Lena H | 2014 | Boreas2014，43，： | 1 |
| 8 | Lung macrophages and dendritic cells express HLA - G molecules in pulmonary diseases 显示文摘 | Pangault C Le Friec G Caulet - Maugendre S Lena H Amiot L Guilloux V Onno M Fauchet R | 2002 | Hum Immunol2002，63，2： | 1 |
| 9 | Chromatin remodelling during develop- ment 显示文摘 | Lena H Crabtree G R | 2010 | Nature2010，463，7280： | 1 |
| 10 | Azgos vein aneurysm: contribution of transesophageal echography 显示文摘 | Lena H Desrues B Heresbach H | 1996 | Ann Thorac Surg1996，61，4： | 1 |
| 11 | A study on the influence of fucosterol on thermal polymerization of purified high oleic sun-flower triacylglycerols显示文摘 | Anna M L Lena H D | 1999 | J Sci Food Agric1999，79，： | 1 |
| 12 | Health care professionals ' ex- periences of parental presence and participation in neonatal inten- sive care unit显示文摘 | Helena W Marie B Anna - lena H | 2007 | International Journal of Qualitative Studies on Health and Well - being2007，2，： | 1 |
| 13 | Increase in macrophage elastase(MMP-12)in lungs from patients with chronic obstructive pulmonary disease显示文摘 | MOLET S BELLEGUIC C LENA H | 2005 | Inflamm Res2005，54，1： | 1 |
| 14 | Pemetrexed and cisplatin as first-line chemotherapy for advanced non-small-cell lung cancer ( NSCLC ) with asymptomatic inoperable brain metastases:a multicenter phase Ⅱ trial (GFPC 07 01)显示文摘 | Barlesi F Gervais R Lena H | 2011 | Ann Oncol2011，22，11： | 1 |
| 15 | Survival of patients with bronchiectasis after the first ICU stay for respiratory failure显示文摘 | Dupont M Gacouin A Lena H | 2004 | Chest2004，125，5： | 1 |
| 16 | Outcomes following liver transplantation in intensive care unit patients显示文摘AIM:To determine feasibility of liver transplantation in patients from the intensive care unit (ICU) by estimating graft and patient survival.METHODS:This single center retrospective study included 39 patients who had their first liver transplant directly from the intensive care unit and 927 non-ICU patients who were transplanted from hospital ward or home between January 2005 and December 2010.RESULTS:In comparison to non-ICU patients,ICU patients had a higher model for end-stage liver disease (MELD) at transplant (median:37 vs 20,P < 0.001).Fourteen out of 39 patients (36%) required vasopressor support immediately prior to liver transplantation (LT) with 6 patients (15%) requiring both vasopressin and norepinephrine.Sixteen ICU patients (41%) were ventilator dependent immediately prior to LT with 9 patients undergoing percutaneous tracheostomy prior to transplantation.Twenty-five ICU patients (64%) required dialysis preoperatively.At 1,3 and 5 years after LT,graft survival was 76%,68% and 62% in ICU patients vs 90%,81% and 75% in non-ICU patients.Patient survival at 1,3 and 5 years after LT was 78%,70% and 65% in ICU patients vs 94%,85% and 79% in non-ICU patients.When formally comparing graft survival and patient survival between ICU and nonICU patients using Cox proportional hazards regression models,both graft survival [relative risk (RR):1.94,95%CI:1.09-3.48,P=0.026] and patient survival (RR:2.32,95%CI:1.26-4.27,P=0.007) were lower in ICU patients vs non-ICU patients in single variable analysis.These findings were consistent in multivariable analysis.Although not statistically significant,graft survival was worse in both patients with cryptogenic cirrhosis (RR:3.29,P=0.056) and patients who received donor after cardiac death (DCD) grafts (RR:3.38,P=0.060).These findings reached statistical significance when considering patient survival,which was worse for patients with cryptogenic cirrhosis (RR:3.97,P=0.031) and patients who were transplanted with DCD livers (RR:4.19,P=0.033).Graft survival and patient survival were not significantly worse for patients on mechanical ventilation (RR:0.91,P=0.88 in graft loss;RR:0.69,P=0.56 in death) or patients on vasopressors (RR:1.06,P=0.93 in graft loss;RR:1.24,P=0.74 in death) immediately prior to LT.Trends toward lower graft survival and patient survival were observed for patients on dialysis immediately before LT,however these findings did not approach statistical significance (RR:1.70,P=0.43 in graft loss;RR:1.46,P=0.58 in death).CONCLUSION:Although ICU patients when compared to non-ICU patients have lower survivals,outcomes are still acceptable.Pre-transplant ventilation,hemodialysis,and vasopressors were not associated with adverse outcomes. | Lena Sibulesky Michael G Heckman C Burcin Taner Juan M Canabal Nancy N Diehl Dana K Perry Darren L Willingham Surakit Pungpapong Barry G Rosser David J Kramer Justin H Nguyen | 2013 | World Journal of Hepatology2013，5，1： | 1 |
| 17 | Pemetrexed and cisplatin as first-line chemotherapy for advanced non-small-cell lung cancer (NSCLC) with asymptomatic inoperable brain metastases: a multicenter phase II trial (GFPC 07-01 ) 显示文摘 | Barlesi F Gervais R Lena H | 2011 | Ann Oncol2011，22，11： | 1 |
| 18 | Pemetrexed and cisplatin as fi rst-line chemotherapy for advanced non-small-cell lung cancer (NSCLC) with asymptomatic inoperable brain metastases: a multi- center phase Ⅱ trial(GFPC07-01)显示文摘 | Barlesi F Gervais R Lena H | 2011 | Ann Oncol2011，22，11： | 1 |
| 19 | Radical-scavenging and antioxidant activity of avenanthramides显示文摘 | Amelie Fagerlund Kerstln Sunnerheim Lena H Dimberg | | Food Chemistry0，113，： | 1 |
| 20 | Four years of ozone exposure at high or low phosphorus reduced biomass in Norway spruce显示文摘 | Susanne Ottosson G?ran Wallin Lena Sk?rby Per-Erik Karlsson Eva-Lena Medin Mats R?ntfors H?kan Pleijel Gun Selldén | 2003 | Trees2003，，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员